Photo of Kevin Joseph Staley, MD

Kevin Joseph Staley, MD

  • Unit Chief, Pediatric Neurology


Accepting New Patients




Centers & Specialties

MassGeneral Hospital for Children

Clinical Interests
  • Epilepsy
  • Neonatal seizures
  • Neurology
  • Pediatric Neurology
Medical Education
  • MD, UC San Diego School of Medicine
  • Residency, UC San Diego Main Campus|Residency, University of Colorado Health Center
  • Fellowship, Stanford University Medical Center
Board Certifications
  • Neurology with Special Qualifications in Child Neurology
  • Boston: Massachusetts General Hospital
Existing Patients
Patient Gateway
Insurances Accepted
  • Aetna Health Inc.
  • AllWays Health (NHP) - ACD
  • AllWays Health (NHP) - PBO
  • Beech Street
  • Blue Cross Blue Shield - Blue Care 65
  • Blue Cross Blue Shield - Indemnity
  • Blue Cross Blue Shield - Managed Care
  • Blue Cross Blue Shield - Partners Plus
  • BMC HealthNet Mass Health MCO/ACO
  • Cigna (PAL #'s)
  • Commonwealth Care Alliance
  • Fallon Community HealthCare
  • Great-West Healthcare (formally One Health Plan)
  • Harvard Pilgrim Health Plan - ACD
  • Harvard Pilgrim Health Plan - PBO
  • Health Care Value Management (HCVM)
  • Humana/Choice Care PPO
  • Maine Community Health Options (MCHO)
  • MassHealth
  • Medicare
  • Medicare - ACD
  • OSW - Connecticut
  • OSW - Maine
  • OSW - New Hampshire
  • OSW - Rhode Island
  • OSW - Vermont
  • Private Health Care Systems (PHCS)
  • Railroad Medicare
  • Railroad Medicare - ACD
  • Senior Whole Health
  • TriCare
  • Tufts Health Plan
  • Unicare
  • United Healthcare (non-HMO) - ACD
  • United Healthcare (non-HMO) - PBO
  • Well Sense Pediatrics

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.

Patient Age Group
Provider Gender


Kevin J. Staley

Joseph P. and Rose F. Kennedy Professor of Child Neurology and Mental Retardation, Harvard Medical School 

Unit Chief, Pediatric Neurology, Mass General Hospital Department of Neurology

Kevin Staley received his MD degree from the University of California, San Diego. He completed his postdoctoral research training at Stanford University School of Medicine. Dr Staley studies neuronal ion transport in neonatal seizures and neural network dysfunction in epilepsy. He has served as Chair of the Investigator's Workshop Committee and the Research and Training Committee of the American Epilepsy Society, as Chair of the Research Council of the Epilepsy Foundation of America, as co-chair of the inaugural Gordon Conference on Mechanisms of Epilepsy and Neuronal Synchronization, and as an Associate Editor for the Journal of Neuroscience.

He is currently the Chief of Pediatric Neurology at Massachusetts General Hospital and the Joseph P. and Rose F. Kennedy Professor of Child Neurology and Mental Retardation, Harvard Medical School.

Research & Publications

Research Summary

Pediatric Epilepsy Research Lab

Neurology Research Investigator Profile

Our long-term research goal is the development of new approaches to the treatment of epilepsy based on a clearer understanding of the necessary steps in seizure initiation and propagation.

The two major themes in the lab are neuronal ion transport and the spread of activity in neural networks. Neuronal ion transport underlies signaling at all fast synapses. The importance of neuronal ion transport was underscored by our recent discovery that reversed ion transport in the immature brain was blocking the effects of the anticonvulsants most commonly used to treat neonatal seizures, and that a safe and well-characterized diuretic could ameliorate this condition.

Our work on the spread of excitation in neural networks combines fluorescent imaging of network activity with computerized analysis and modeling to understand how normal and abnormal signaling progresses through neural networks. We have found evidence for reentrant or circular patterns of neural activity that resemble cardiac fibrillation and precede seizures. We are currently testing whether this reentrant activation of neural circuits is the earliest stage of a seizure, and the stage at which intervention is most effective. We are also testing whether long-term reductions in the strength of synaptic connections between neurons in epileptic networks can reduce the probability of seizures.


View my most recent publications at PubMed

  1. Glykys, J, Staley, KJ. Diazepam effect during early neonatal development correlates with neuronal CL. Annals of Clinical Neurology, September 16, 2015, doi: 10.10002/acn7.259
  2. Shapiro, KA, McGuone, D, Deshpande, V, Sadow, PM, Stemmer-Rachamimov, A, Staley, KJ. Failure to detect human papillomavirus in focal cortical dysplasia type II, Annals of Neurology, Volume 78, Number 1, 1 July 2015, pp. 63-67
  3.  Dzhala V, Staley KJ. Acute and Chronic Efficacy of Bumetanide in an in vitro Model of Posttraumatic Epileptogenesis. CNS Neurosci Ther. 2015 Feb; 21(2):173-80.
  4. Lillis KP, Wang Z, Berdichevsky Y, Mail M, Zhao G, Bacskai B, Staley KJ, Evolution of network synchronization during early epileptogenesis parallels synaptic circuit alterations. J Neurosci., 2015 Jul 8; 35(27):9920-34
  5. Kyung-Il Park, Volodymyr Dzhala, Yero Saponjian, Kevin J. Staley, what elements of the inflammatory system are necessary for epileptogenesis In Vitro. eNeuro. Mar 2015, 2 (2) DOI: 10.1523/ENEURO.0027-14.2015
  6. Lillis KP, Dulla C, Maheshwari A, Coulter D, Mody I, Heinemann U, Armbruster M, ?iburkus J.,WONOEP appraisal: Molecular and cellular imaging in epilepsy. Epilepsia 56:505?513. 2015
  7. Kevin Staley, Molecular Mechanisms of Epilepsy. Nature Neuroscience. 18, 367-372, doi:10.1038/nn 3947, 2015

News & Events


  • Neurology Bicentennial Celebration, 2011 Part I

    Neurology Bicentennial Celebration, October 13, 2011. Past History of MGH Neurology; Overview of MGH Neurology; Telestroke and Acute Stroke Service; Neurodegenerative Disorders; Pediatric Neurology.


Pediatric Neurology
55 Fruit Street
WAC 708-D
Boston, MA 02114-2696
Phone: 617-726-3877
Fax: 617-724-7860

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