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Deborah Mitchell, MD, is a clinician in the MGHfC Pediatric Endocrine Unit and a clinical investigator in the Endocrine Division of Mass General. She is the Associate Director of the pediatric endocrine training program at MGHfC and the Co-Director of the pediatric bone and mineral metabolism clinic.
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MassGeneral Hospital for Children
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Deborah Mitchell, MD, is a pediatric endocrinologist with particular interests in calcium and bone metabolism. She completed pediatric residency at Massachusetts General Hospital for Children (MGHfC) in 2009, and a fellowship in pediatric endocrinology at MGHfC in 2012. She is the Associate Director of the pediatric endocrine training program at MGHfC and co-director of the pediatric Bone and Mineral Metabolism Clinic.
Dr. Mitchell's research is concerned with factors which promote optimal bone growth and mineralization during childhood and adolescence, with a goal of preventing osteoporosis and fractures in adults. She is currently investigating bone accrual and microarchitecture in children with type 1 diabetes, a condition known to increase the risk of bone fragility. Her goal is to better understand why patients with diabetes are at increased risk of fracture in order to be able to design and test therapies to strengthen bones in this population.
In addition, Dr. Mitchell is interested in rare disorders of calcium and phosphate metabolism including hypoparathyroidism, pseudohypoparathyroidism, and X-linked hypophosphatemic rickets. In particular, her research has demonstrated extremely high rates of kidney disease among patients treated for hypoparathyroidism. Ongoing studies are investigating determinants of renal disease in this population as well as novel, targeted therapies.
Learn more about research at the Pediatric Endocrine Program and Diabetes Center.
View my most recent publications at PubMed
Selected Research Articles:
Childhood is a critical time for bone health. Approximately 90% of peak bone mass is acquired by age 18, with about 50% of this acquired during the pubertal growth spurt. As a pediatrician, my research goal is to better understand the factors which impact bone growth and mineralization during this important window in order to maximize long-term bone health.
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