Key Takeaways

  • Duodenal atresia occurs during development and causes a blockage in the baby’s intestine.
  • With a bowel obstruction, the baby cannot digest food normally.

What is Duodenal Atresia?

Duodenal atresia is a condition in which there is a developmental problem with a baby’s duodenum. The duodenum is the part of the small intestine that connects the stomach to the rest the intestine. Atresia means that there is a blockage in this passageway. This limits food and fluid from leaving your baby’s stomach.

The blockages (also known as the atretic area) can be partial or complete.

  • Partial blockages mean that the duodenum is narrow so very little stomach contents can pass through into the intestines.
  • Complete atresia separates the duodenum into 2 sections. The stomach and intestines are no longer connected, and no contents can pass out of the stomach.

Is Duodenal Atresia Common?

Duodenal atresia is the most common duodenal obstruction (blockage) in newborns. It is found in about 1 in every 7,500 babies. Duodenal atresia can occur as an isolated condition (by itself with no other birth defects) or with other conditions.

In about 1 out of every 3 cases, babies with duodenal atresia also have a genetic condition called trisomy 21 (Down syndrome).

What Causes Duodenal Atresia in Babies?

Doctors do not know exactly what causes duodenal atresia. They do know, however, that genetics may play a role. During pregnancy, your baby’s duodenum normally develops from a solid form into a hollow tube in a process called recanalization. If recanalization is interrupted, the duodenum does not form into a tube and the remaining solid parts are the cause of the atresia.

What Are the Symptoms of Duodenal Atresia?

Before birth:

  • Extra amniotic fluid in the uterus (also called polyhydramnios, which happens when your baby is not swallowing and digesting amniotic fluid properly) 

After birth:

  • Swelling of your baby’s stomach
  • Passing stool less often than babies without duodenal atresia
  • Vomiting (often green-colored)
  • Not tolerating feedings (vomiting or not feeding well)
  • No weight gain