Photo of happy, healthy child

Pediatric Cystic Fibrosis Center

The Joey O'Donnell Cystic Fibrosis Center at MassGeneral Hospital for Children is committed to providing first-class, individualized care for each patient with cystic fibrosis.

CF clinic main number: 617-726-8707

Contact the CF nurse line at 617-643-2223

Overview

Cystic fibrosis(CF) is a complex, inherited disease that causes a defect in the electrolyte transport system, leading to problems in the function of many organ systems such as the lungs and gastrointestinal tract. CF affects about 30,000 people in the United States. Although there is no cure yet, comprehensive care has led to improved prognoses for many individuals living with CF and research is providing new insights and new therapies.

The Pediatric Cystic Fibrosis Program at MassGeneral Hospital for Children (MGHfC) is a Cystic Fibrosis Foundation (CFF) accredited pediatric CF clinic committed to providing first-class, individualized care for each patient. We have an established multidisciplinary team to provide preventive care, active management of lung health, nutrition support and psychological support. Optimal treatment is accomplished through frequent outpatient visits with the CF care team, direct communication with families, and educational programs.

The Massachusetts General Hospital (MGH) Cystic Fibrosis Center is comprised of the Pediatric CF Program and the Adult CF Program. Members of these care teams work closely to provide optimal care across all ages, with a fluid transition from the pediatric program to the adult program. For more information on the adult CF program, please visit theAdult Cystic Fibrosis Center page.

For families coping with a positive result from a CF newborn screening test, we offer a state-of-the-art system for CF diagnostic testing (sweat chloride testing), and our CF specialists will meet with you the same day to discuss the test results.
For sweat test appointments please call: 617-724-0703 or 617-724-2992. Orders can be faxed to 617-724-2803 (ATTN: Sweat Test Laboratory)

Our CF Care Team

Our CF Care Team: Comprehensive Services and Multidisciplinary Health Professionals

The Cystic Fibrosis Center is staffed with a dedicated multidisciplinary team of cystic fibrosis specialists including:

Physicians certified in pediatric pulmonology

Fracchia, Mary Shannon, MD

617-726-8707

Accepting New Patients 

Clinical Interests

  • Cystic fibrosis
  • Asthma 
  • Pediatric lung disease 
  • Aerodigestive disorders

Board Certifications

  • Pediatrics, American Board of Pediatrics 
  • Pediatric Pulmonology, American Board of Pediatrics

Locations

  • Boston: Pediatric Pulmonary
  • Newton: Newton Wellesley Hospital
  • Braintree: Blue Hills Medical Center

Yonker, Lael M., MD

617-726-8707

Accepting New Patients    

Clinical Interests

  • Pediatric pulmonary disease 
  • Cystic fibrosis
  • Childhood interstitial lung disease (ChILD)
  • Genetic pulmonary diseases
  • Asthma
  • Chronic cough
  • Recurrent pneumonia 

Board Certifications

  • Pediatrics, American Board of Pediatrics
  • Pediatric Pulmonology, American Board of Pediatrics 

Locations

  • Boston: Pediatric Pulmonary, MGHfC Pediatric Cystic Fibrosis Center

Lapey, Allen, MD

617-726-8707

Accepting New Patients 

Clinical Interests

  • Asthma (adult and pediatric)
  • Clinical allergy
  • Cystic fibrosis
  • Immunodeficiency
  • Bronchiectasis 
  • Asthma
  • Allergies
  • Show 2 More

Board Certifications

  • Allergy & Immunology, American Board of Internal Medicine
  • Pediatrics, American Board of Pediatrics 

Locations

  • Boston: Pediatric Pulmonary, MGHfC Pediatric Cystic Fibrosis Center
  • Boston: Pediatric Allergy and Immunology 

Kinane, Thomas Bernard, MD

617-726-8707

Accepting New Patients

Clinical Interests

  • Pulmonary disorders
  • Asthma
  • Bronchopulmonary dysplasia
  • Interstitial lung disease
  • Congenital pulmonary disease 
  • Exercise physiology (particularly exercise intolerance)
  • Obstructive sleep apnea
  • Respiratory disorders affecting sleep and exercise
  • Primary ciliary dyskinesia
  • Congenital central hypoventilation syndrome
  • Sleep/Breathing Disorders
  • Cystic fibrosis
  • Show 7 More 

Board Certifications

  • Pediatric Pulmonology, American Board of Pediatrics
  • Sleep Medicine, American Board of Internal Medicine

Locations

  • Boston: Pediatric Pulmonary, MGHfC Pediatric Cystic Fibrosis Center 
  • Boston: Pediatric Sleep Lab 
  • Boston: Administrative Office
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 Psychiatry Clinicians

Georgiopoulos, Anna Maria, MD

617-724-5600

Accepting New Patients

Clinical Interests

  • Cystic fibrosis
  • Psychiatry

Board Certifications

  • Psychiatry, American Board of Psychiatry and Neurology
  • Child & Adolescent Psychiatry, American Board of Psychiatry and Neurology
  • Psychosomatic Medicine, American Board of Psychiatry and Neurology

Locations

  • Boston: Psychiatry Department

Friedman, Deborah R., PhD

617-724-6300

Accepting New Patients

Clinical Interests

  • Cystic fibrosis 

Locations

  • Boston: Psychiatry Department 
  • Boston: Child and Adolescent Cognitive Behavioral Therapy Program


Nurses   

Anita St. John, RN, -AE-C 

Nutritionists

Gretchen M. Garlow, MS, RD, LDN, CNSC

Physical Therapists

Jessica Garton, DT, DPT, OCS

Respiratory Therapists

Pat Costello, RRT, CPFT 

Pediatric Pulmonary Function Testing Laboratory

The Pulmonary Function Testing Laboratory at MGHfC has comprehensive state-of-the-art facilities for performing and interpreting pulmonary function testing in children. The lab is registered with the American Thoracic Society and serves the Cystic Fibrosis Foundation Accredited Care Center.

For testing appointments please call: 617-724-0703 or 617-724-2992Orders can be faxed to 617-724-2803 (ATTN: Pulmonary Function Laboratory)

Social workers

Caitlin Miller, LICSW

The other medical needs of our patients are assessed by a comprehensive group of pediatric specialists at MGHfC, including:

Pediatric Ear, Nose and Throat (ENT) Specialists  are available from the adjoining Massachusetts Eye and Ear Infirmary.

Conditions & Diseases

  • Cystic Fibrosis

    Cystic fibrosis (CF) is an inherited chronic disease that affects the lungs and digestive system. CF causes the body to produce thick, sticky mucus that leads to progressive lung infection and difficulty gaining weight.

Patient Resources

A Tradition of Caring

At MGHfC, we know that the time of your child’s diagnosis and treatment is a very stressful one and we strive to provide an open, welcoming environment. We believe that no one knows a child as well as their parent does. Parents and caregivers, along with primary care providers, become our partners in a child's care and have an active voice in all treatment plans.

Infection Prevention

An important issue related to patient care involves preventing the spread of harmful bacteria. We follow the CFF Infection Prevention and Control Care Guidelines in order to protect our CF patients in the clinic and hospital setting.

Inpatient Care

Individuals with CF may need to stay in the hospital (inpatient) for the management of a chest infection or other complications of their disease. Children and adolescents are admitted to the pediatric inpatient units at the MGHfC, which are located on the 17thand 18thfloors of the Ellison Building at MGH. More information regarding inpatient visits at MGHfCcan be found here. Specifically, we encourage our CF patients to bring all of their home medications with them for admission, as well as sneakers and athletic gear or comfortable clothing for our young patients and adolescents to fully participate in chest physical therapy.

Lung Transplant

For patients with advanced lung disease, one life-lengthening treatment option to consider is lung transplant. We work closely with patients, families, and the lung transplant team at MGH to promote patient education regarding this surgical procedure and to ensure a smooth transition to lung transplant evaluation when indicated.

Transition Program

As children with cystic fibrosis get older, they have different needs. We partner with families to facilitate teenagers’ transition to self-care, which includes a gradual transition to the Adult Cystic Fibrosis Program. The MGH Cystic Fibrosis Center is in the unique position to follow patients from infancy into adulthood and offer smooth continuity of care for patients as they transition from a pediatric to an adult CF provider.

Clinical Trials

Cutting-Edge Clinical and Basic Research

MGHfC is a Cystic Fibrosis Foundation supported therapeutic development center and part of the nationwide therapeutic development network. Critical cutting-edge clinical research forms the basis of therapeutic advances, and our program is involved in most major clinical trials. Currently, we offer over 15 clinical therapeutic trials for CF patients, with therapeutic treatments targeting CFTR modulation (“correctors”), inflammation, and airway mucociliary clearance. If you are interested in participating in any of these clinical trials, please contact our research team at 617-726-3716 or mghfcclinicalresearch@partners.org or email our senior clinical research coordinator, Hanna Pinsky athpinsky@mgh.harvard.edu.

To find a clinical trial that is right for you, go to the CFF Clinical Trial Finder.

MGH has a strong history of leading the field in basic, translational and clinical research. CF-specific research programs at MGH include groups focused on:

Additional Resources

News

  • MGHfC highlights innovations in pediatric research at 11th Annual Research Day - 5/9/2019, Mass General

    This past May marked the 11th anniversary of MGHfC Research Day, an annual event that recognizes the pioneering research of investigators throughout the hospital whose discoveries help to better understand childhood health and disease. The focus of this years’ event was on innovation and taking children’s health and medicine even farther into the future with cutting edge care and research.

  • Simple Steps to Cure a Complex Disease - 3/23/2017, Mass General

    Laura Williams, RN, of the Ellison 18 pediatric inpatient unit, will take on the Boston Marathon April 17 to benefit the Joey O'Donnell Cystic Fibrosis Center at MassGeneral Hospital for Children.

  • Success for Mass General Marathon Teams - 4/25/2014, Mass General

    The 2014 Boston Marathon marked a triumphant return for the Mass General Marathon teams.

  • Breakthrough cystic fibrosis drug gives hope, transforms lives - 12/6/2012, Mass General

    Praised by experts as a breakthrough for patients with a particular form of cystic fibrosis, ivacaftor was approved by the United States Food and Drug Administration (FDA) in January 2012 and is the first of its kind to treat the underlying defects of the disease, rather than manage its symptoms.

  • Going the distance - 4/20/2012, Mass General

    Crossing the finish line of a marathon is a feat in itself, but completing the race and supporting a good cause is a triumph times two.

  • Mass General Researchers Take Major Step Toward a Treatment for Cystic Fibrosis - 4/5/2012, Mass General

    Researchers in the Center for Regenerative Medicine at Massachusetts General Hospital and the Harvard Stem Cell Institute have taken a critical step toward a treatment for Cystic fibrosis and other fatal lung diseases.

Contact

CONTACT US

MGHfC Pediatric Cystic Fibrosis Center

MGH Professional Office Building

275 Cambridge Street, Suite 530Boston, MA 02114

  •  Near Public Transit
  •  Accessible
  • Phone: 617-726-8707

HOURS

8 am – 5 pm, Monday – Friday

Appointment Line: 617-726-8707

MGH New Patient Registration: 866-211-6588

MGHfC New Patient Appointments (Access Center): 888-644-3248

Nurse Line: 617-643-2223Fax: 617-724-2803

Pulmonary Function and Sweat Chloride Testing Laboratory

For testing appointments please call: 617-724-0703 or 617-724-2992

Orders can be faxed: 617-724-2803 (ATTN: Pulmonary Function Laboratory)

Follow us on Facebook @Mass General Hospital for Children Cystic Fibrosis Center.

CF clinic main number: 617-726-8707

Contact the CF nurse line at 617-643-2223

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