About Joshua Goldstein, MD, PhD

Dr. Goldstein is an emergency physician who specializes in neurologic emergencies. He received both his M.D. and Ph.D. from the University of Connecticut in 2000, and completed his residency at the Harvard Affiliated Emergency Medicine Residency in 2005. He then completed a research fellowship in Vascular and Critical Care Neurology at Massachusetts General Hospital and Brigham & Women’s Hospital. He is currently the Vice Chair for Faculty Affairs and the Co-Director of the Center for Neurologic Emergencies in the Department of Emergency Medicine at Massachusetts General Hospital; a Professor of Emergency Medicine at Harvard Medical School; and the MGH Endowed Chair in Emergency Medicine Research. 

He is a Fellow of the Neurocritical Care Society, the American Heart Association, the American College of Emergency Physicians, and the American Academy of Emergency Medicine. 

Dr. Goldstein manages clinical research program integrating neurology, hematology, neurocritical care, and emergency medicine. He has been continually NIH funded since 2009, and receives funding from foundations and industry, and consults for multiple pharmaceutical and biotech companies on drug development and clinical trial management. 

He currently serves as the hub PI for the New England SIREN group, an NIH funded national network that performs large phase III clinical trials in emergency and critical care (published in journals such as NEJM and Lancet).

He has served as an invited speaker at many national and international forums, and has published over 200 peer reviewed articles in journals such as Stroke, Neurology, and Lancet, and over 40 reviews and book chapters. He is a co- Editor of the textbook Neurologic Emergencies, and directs CME courses on Neurologic Emergencies that draw hundreds of participants from across the world annually. 

Departments, Centers, & Programs:

Clinical Interests:



Mass General Emergency Medicine: Center for Vascular Emergencies
Zero Emerson Place
Suite 3B
Boston, MA 02114
Phone: 617-724-3290

Medical Education

  • MD, University of Connecticut School of Medicine
  • Residency, Brigham and Women's Hospital
  • Fellowship, Massachusetts General Hospital

American Board Certifications

  • Emergency Medicine, American Board of Emergency Medicine

Accepted Insurance Plans

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Dr. Goldstein currently manages a research program focused on improving the care of patients with neurological emergencies. With support from NIH, industry, and nonprofit sources, his team performs clinical trials in diseases such as stroke, intracerebral hemorrhage, and emergency anticoagulation reversal. He is the Principal Investigator for a New England-wide consortium of centers for the NIH-funded SIREN network of emergency care clinical trials. Dr Goldstein has lectured nationally and internationally, and has published over 140 original peer-reviewed research articles in the medical literature.

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