Radiation oncologists demonstrate in an early clinical trial that the radiation beam can be carefully “sculpted” to deliver the majority of a dose directly to the tumor while effectively sparing tissues in the side of the esophagus away from the affected lung.
Departments, Centers, & Programs:
Clark Center for Radiation Oncology
100 Blossom Street
Boston, MA 02114-2606
- MD, Northwestern University, Feinberg School of Medicine
- PhD, University of Michigan Medical School
- Residency, Brigham and Women's Hospital
- Residency, MGH/Harvard Radiation Oncology Program
American Board Certifications
- Radiation Oncology, American Board of Radiology
Accepted Insurance Plans
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Dr. Khandekar's clinical research activities focus on the application of stereotactic body radiation therapy (SBRT) in patients with early-stage and metastatic NSCLC as well as lung metastases and optimizing the role of radiation therapy in the management of brain metastases from NSCLC
Dr. Khandekar's lab research aims to understand the effects of alterations of the systemic physiology of the patient, including comorbidities such as hypertension, diabetes and obesity on the tumor and tumor microenviroment. He hopes to repurpose drugs developed to treat these conditions, including anti-diabetic agents that modulate PPAR-gamma as well as anti-hypertensives that block renin-angiotensin signaling to identify optimal combinations of systemic therapy and radiation that will improve the chance to cure lung cancer and other thoracic cancers.