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Accumulation of amyloid-β and tau proteins are related to brain network changes years before symptoms
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Dr. Quiroz is Associate Professor in the Departments of Psychiatry and Neurology at Massachusetts General Hospital, Harvard Medical School. She is a Clinical Neuropsychologist and serves as Director of the Multicultural Assessment and Research Center-MARC. She is also the Director of the Multicultural Alzheimer's Prevention Program (MAPP) and the Familial Dementia Neuroimaging Lab, where she leads several research studies on aging, Alzheimer's disease and other dementias.
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Dr. Quiroz is Associate Professor in the Departments of Psychiatry and Neurology. Her research is focused on the study of age-related cognitive and brain changes that may predispose individuals to develop dementia later in life. Understanding the pathophysiology of neurodegeneration and identifying biomarkers for early diagnosis of dementia, especially as measured by neuropsychology , biofluids and neuroimaging, are fundamental goals of her research. Her current studies use multimodal neuroimaging (e.g. PET, sMRI, fMRI, DTI) and integrate genetics, molecular and neuropsychological data to characterize some of the earliest changes associated with increased risk for Alzheimer's disease and other dementias.
Arboleda-Velasquez JF, Lopera F, O'Hare M, ... Johnson KA, Reiman EM, Quiroz YT. Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report. Nat Med. 2019 Nov;25(11):1680-1683. doi: 10.1038/s41591-019-0611-3. Epub 2019 Nov 4. PubMed PMID: 31686034; PubMed Central PMCID: PMC6898984.
Quiroz YT, Sperling RA, Norton DJ, Baena A, Arboleda-Velasquez JF, Cosio D, Schultz A, Lapoint M, Guzman-Velez E, Miller JB, Kim LA, Chen K, Tariot PN, Lopera F, Reiman EM, Johnson KA. Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease. JAMA Neurol. 2018 May 1;75(5):548-556. doi: 10.1001/jamaneurol.2017.4907. PubMed PMID: 29435558; PubMed Central PMCID: PMC5885174.
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Accumulation of amyloid-β and tau proteins are related to brain network changes years before symptoms
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Research at the MGH is interwoven throughout more than 30 departments, centers and units and is conducted with the support and guidance of the MGH Research Institute. The Research Roundup is a monthly series highlighting studies, news and events.
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Multicultural Neuropsychology Program Changes Outcomes for Latino Population