Person’s living with HIV (PLWHIV) are at an increased risk of cardiovascular disease. The risk of heart failure among men living with HIV is increased. There are little data about the risk of heart failure among women living with HIV. Leveraging data from a large US health care system-based cohort, Dr. Neilan and colleagues found that heart failures outcomes differ markedly by HIV status among women. Specifically, women with HIV with heart failure have higher rates of heart failure hospitalization, longer heart failure hospitalizations, and higher rates of all-cause and cardiovascular mortality. This study is the first to report heart failure outcome differences among women with and without HIV. In this era of effective ART, understanding how HIV status influences the development of heart failure and heart failure outcomes in women will be of critical public health importance to the 14 million women aging with HIV worldwide.