Synovial Sarcoma
Contact Information
Orthopaedic Oncology Service
Mass General - Boston
55 Fruit Street
Yawkey Building, Suite 3B
Boston,
MA
02114
Phone: 617-724-3700
Fax: 617-726-6823
Explore Synovial Sarcoma
Synovial Sarcoma is a malignant soft tissue tumor that arises near, but not, as the name implies, in the joint itself. About 10% of soft tissue sarcomas are synovial sarcomas.
The patient usually presents with a painful mass next to a joint which is growing in size. It usually occurs in teenagers or patients under 40 years of age, most often in the lower leg around the knee. Lower grade synovial sarcomas tend to be found on the hands or feet, and may be confused with a benign ganglion. X-rays show a soft tissue thick shadow with calcifications (deposits of calcium salts in normal bone or in soft tissue (less common)) in it. A biopsy is necessary to rule out the many other possible soft tissue masses that have calcifications but are benign. Metastases to lymph nodes are more common with synovial sarcoma than other types of soft tissue sarcomas. The tumor may also spread to the lungs in more advanced cases. Treatment consists of radical or wide excision of the tumor with adjuvant therapy (chemotherapy and/or radiation therapy). Small, low-grade tumors may do well with excision only.
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- Acting Chief, Orthopaedic Oncology Service
- Program Director, Musculoskeletal Oncology Fellowship Program
- Assistant Professor of Orthopaedic Surgery, Harvard Medical School
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Santiago Lozano Calderon, MD, PhD
- Orthopaedic Oncology Surgeon
- Instructor in Orthopaedic Surgery, Harvard Medical School
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- Orthopaedic Oncology Surgeon
- Instructor in Orthopaedic Surgery, Harvard Medical School
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- Chief, Orthopaedic Spine Surgery
- Director, Spine Oncology & Co-Director, Stephan L. Harris Chordoma Center
- Associate Professor of Orthopedic Surgery, Harvard Medical School
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- Nurse Practitioner, Doctor of Nursing, Clinical Administrator for Orthopaedic Oncology Service
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- Inpatient Nurse Practitioner
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