Graduate Students

Visiting Graduate Student

The Harris Orthopedic Laboratory (HOL) at MGH specializes in translational research for orthopedic biomaterials and implants. HOL is looking to train MD/PhD and PhD students in polymeric material development and translational research in orthopaedics. The laboratory is a focal point in the orthopedic research community for development of new materials, designs and clinically relevant testing methodology for total joint replacements, which are implanted in over 1 million patients in the US alone each year. This is a great opportunity for science and engineering students looking for hands-on experience in biomedical applications.

We are interested in a variety of topics pertaining to orthopaedics such as improving the performance of materials, designs and developing methodologies to help bridge the gap between in vitro testing and in vivo performance of implantable devices. We are interested in treating orthopaedic conditions such as post-traumatic arthritis, peri-prosthetic osteolysis, peri-prosthetic and post-traumatic infection, and pain management.

We are open to collaborations where graduate students already enrolled in a PhD program in science or engineering with the pertinent experience can incorporate 1-2 years of laboratory training at the HOL into their thesis work.

Contact Person: Ebru Oral, PhD (eoral@mgh.harvard.edu)


Post-Doctoral Fellowships

There are no available openings at this time


Material Engineering & Preclinical Research

There are no available openings at this time.


Clinical Studies

There are no available openings at this time.


Clinical Fellowships

There are no available openings at this time.


Undergraduate Internships

Overview
Harris Orthopaedics Laboratory is focused on the development of polymeric and hybrid materials for applications in orthopaedics. A Spring semester-long Research Intern, 16 hours per week position with a $275/week stipend is available from January 2022 to May 2022. As this is a hands-on research opportunity, all research will be conducted at the lab. Based on performance, the candidate will also be considered for a full-time summer internship from mid-May 2022 - August 2022. The internship will include an introduction to material formulation and testing of drug delivery devices in orthopaedic applications such as joint arthroplasty and trauma. The intern will have the opportunity to be exposed to the translational research environment through interaction with other members of the Harris Orthopaedics Laboratory and gain insight into design of medical devices, pre-clinical testing of safety and efficacy and clinical follow-up research of implanted materials.

Depending on the specific project, responsibilities will include some of the following activities:

  • Laboratory formulation including preparation of polymers, blends of polymers, photo and thermal polymerization, polymeric consolidation, nano- and micro-particle synthesis
  • Chemical characterization of polymers, byproducts and drugs including elution testing using NMR, LC/MS and UV-Vis spectroscopy analysis
  • Antibacterial characterization of polymeric materials in a BSL-2 setting
  • May include support for pre-clinical testing including preparing animal tissue and blood specimens for post-surgical analysis and characterization of retrieved implants

General laboratory functions:

  • Assembly, operation, maintaining standard operation protocols, and some maintenance of used equipment
  • Maintaining clean equipment, glassware, and laboratory space
  • Working alongside research technologists, MD students, PhD students and post-doctoral fellows following institution and laboratory standards

Administrative/reporting functions:

  • Organizing and accurately maintaining written records of procedures and data
  • Generating and compiling experimental information/results in graphs, charts, and reports
  • Preparing written and/or verbal reports for supervisor and/or senior research personnel

Skills/Abilities/Qualifications:

  • The ideal candidate will be a rising senior (pre-med track is welcome), majoring preferably in Chemical/Biomedical Engineering who has demonstrated strong academic performance (minimum 3.3 GPA is preferred).
  • Coursework and/or internship experience in polymeric materials a plus.
  • Robust written and oral communication skills, attention to detail, and strong organizational skills are all expected. Independence, self-motivation, and a willingness to learn new skills are also vital for succeeding in this position.

How to Apply
Please submit your resume, cover letter, and your unofficial transcript to Slav Lerner, vlerner@mgh.harvard.edu by January 15, 2022. We will start reviewing the applications as we receive them. Earlier applicants will receive priority.