Largest study of its kind reveals that many psychiatric disorders arise from common genes
In the largest-ever study of its kind researchers identified more than 100 genetic variants that affect the risk for more than one mental health condition.
Jordan Smoller, MD, is a psychiatrist, epidemiologist and geneticist whose research focus has been understanding the genetic and environmental determinants of psychiatric disorders across the lifespan and using big data to advance precision mental health including improved methods to reduce risk and enhance resilience.
Dr. Smoller earned his undergraduate degree summa cum laude at Harvard University and his medical degree at Harvard Medical School. After completing residency training in psychiatry at McLean Hospital, he received masters and doctoral degrees in epidemiology at the Harvard School of Public Health.
Dr. Smoller is the Massachusetts General Hospital Trustees Endowed Chair in Psychiatric Neuroscience, professor of Psychiatry at Harvard Medical School and professor in the Department of Epidemiology at the Harvard School of Public Health in Boston. He is associate chief for research in the Mass General Department of Psychiatry, director of the Center for Precision Psychiatry, and director of the Psychiatric and Neurodevelopmental Genetics Unit in the Mass General Center for Genomic Medicine. Dr. Smoller is a Tepper Family MGH Research Scholar and also serves as director of the Omics Unit of the Mass General Division of Clinical Research and co-director of the Mass General Brigham Biobank. He is director of the Mass General Brigham Training Program in Precision and Genomic Medicine, an associate member of the Broad Institute, co-chair of the Cross-Disorder Workgroup of the Psychiatric Genomics Consortium, and president of the International Society of Psychiatric Genetics.
He has played a leading role in national and international efforts to advance precision medicine. He is a Principal Investigator (PI) in the eMERGE (Electronic Medical Records and Genomics) network, founding PI of the PsycheMERGE Consortium and lead PI of the New England Precision Medicine Consortium as part of the NIH All of Us Research Program and co-Chair of the All of Us Science Committee. Dr. Smoller is an author of more than 400 scientific publications and is also the author of The Other Side of Normal (HarperCollins/William Morrow, 2012).
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