Recent Publications List
For more information on the Center's faculty, visit the Our Team page. 


Stein MB, Jain S, Campbell-Sills L, Ware EB, Choi KW, He F, Ge T, Gelernter J, Smoller JW, Kessler RC, Ursano RJ. Polygenic risk for major depression is associated with lifetime suicide attempt in US soldiers independent of personal and parental history of major depression. Am J Med Genet B Neuropsychiatr Genet. 2021 Dec;186(8):469-475. doi: 10.1002/ajmg.b.32868. Epub 2021 Jul 21. PMID: 34288400; PMCID: PMC8692314.

Bentley KH, Madsen EM, Song E, Zhou Y, Castro V, Lee H, Lee YH, Smoller JW. Determining Distinct Suicide Attempts From Recurrent Electronic Health Record Codes: Classification Study. JMIR Form Res. 2024 Jan 8;8:e46364. doi: 10.2196/46364. PMID: 38190236; PMCID: PMC10804255.

Walsh CG, Ripperger MA, Hu Y, Sheu YH, Lee H, Wilimitis D, Zheutlin AB, Rocha D, Choi KW, Castro VM, Kirchner HL, Chabris CF, Davis LK, Smoller JW. Development and multi-site external validation of a generalizable risk prediction model for bipolar disorder. Transl Psychiatry. 2024 Jan 25;14(1):58. doi: 10.1038/s41398-023-02720-y. PMID: 38272862; PMCID: PMC10810911.


Burke TA, Bettis AH, Walsh RFL, Levin RY, Lawrence HR, Sheehan AE, Turnamian MR, Liu RT. Nonsuicidal Self-Injury in Preadolescents. Pediatrics. 2023 Dec 1;152(6):e2023063918. doi: 10.1542/peds.2023-063918. PMID: 37916265; PMCID: PMC10657775.

Ross EL, Bossarte RM, Dobscha SK, Gildea SM, Hwang I, Kennedy CJ, Liu H, Luedtke A, Marx BP, Nock MK, Petukhova MV, Sampson NA, Zainal NH, Sverdrup E, Wager S, Kessler RC. Estimated Average Treatment Effect of Psychiatric Hospitalization in Patients With Suicidal Behaviors: A Precision Treatment Analysis. JAMA Psychiatry. 2024 Feb 1;81(2):135-143. doi: 10.1001/jamapsychiatry.2023.3994. PMID: 37851457; PMCID: PMC10585585.

Kachuri L, Chatterjee N, Hirbo J, Schaid DJ, Martin I, Kullo IJ, Kenny EE, Pasaniuc B, PRIMED Consortium Methods Working Group, Witte JS, Ge T.  Principles and Methods for Transferring Polygenic Risk Scores Across Global PopulationsNat Rev Genet (2023).

Tubbs JD
, Sham PC. Preliminary Evidence for Genetic Nurture in Depression and Neuroticism Through Polygenic Scores. JAMA Psychiatry. 2023 Jun 7:e231544. doi: 10.1001/jamapsychiatry.2023.1544. Epub ahead of print. PMID: 37285136; PMCID: PMC10248817.

Choi KW, Lee YH, Liu Z, Fatori D, Bauermeister JR, Luh RA, Clark CR, Brunoni AR, Bauermeister S, Smoller JW. Social support and depression during a global crisisNat. Mental Health 1, 428–435 (2023).

Grotzinger AD, Singh K, Miller-Fleming TW, Lam M, Mallard TT, Chen Y, Liu Z, Ge T, Smoller JW. Transcriptome-Wide Structural Equation Modeling of 13 Major Psychiatric Disorders for Cross-Disorder Risk and Drug Repurposing. JAMA Psychiatry. 2023 Jun 14:e231808. doi: 10.1001/jamapsychiatry.2023.1808. Epub ahead of print. PMID: 37314780; PMCID: PMC10267850.

Sheu YH, Magdamo C, Miller M, Das S, Blacker D, Smoller JW. AI-assisted prediction of differential response to antidepressant classes using electronic health records. NPJ Digit Med. 2023 Apr 26;6(1):73. doi: 10.1038/s41746-023-00817-8. PMID: 37100858; PMCID: PMC10133261.

Sheu YH, Sun J, Lee H, Castro VM, Barak-Corren Y, Song E, Madsen EM, Gordon WJ, Kohane IS, Churchill SE, Reis BY, Cai T, Smoller JW. An efficient landmark model for prediction of suicide attempts in multiple clinical settings. Psychiatry Res. 2023 May;323:115175. doi: 10.1016/j.psychres.2023.115175. Epub 2023 Mar 21. PMID: 37003169.

Grotzinger AD, Mallard TT, Liu Z, Seidlitz J, Ge T, Smoller JW. Multivariate genomic architecture of cortical thickness and surface area at multiple levels of analysis. Nat Commun. 2023 Feb 20;14(1):946. doi: 10.1038/s41467-023-36605-x. PMID: 36806290; PMCID: PMC9941500.

Mallard TT, Grotzinger AD, Smoller JW. Examining the shared etiology of psychopathology with genome-wide association studies. Physiol Rev. 2023 Apr 1;103(2):1645-1665. doi: 10.1152/physrev.00016.2022. Epub 2023 Jan 12. PMID: 36634217; PMCID: PMC9988537.


Kleiman EM, Bentley KH, Wacha-Montes A, Taylor ME, Lozy O, Conti K, Reese Mayer W. A Pilot Implementation-Effectiveness Trial of a Single-Session Telehealth Workshop and Smartphone-Based Cognitive Behavioral Intervention for Managing Emotions Among College Students. Behav Ther. 2022 Sep;53(5):1024-1036. doi: 10.1016/j.beth.2022.04.008. Epub 2022 Apr 29. PMID: 35987533.

Lee YH, Liu Z, Fatori D, Bauermeister JR, Luh RA, Clark CR, Bauermeister S, Brunoni AR, Smoller JW. Association of Everyday Discrimination With Depressive Symptoms and Suicidal Ideation During the COVID-19 Pandemic in the All of Us Research Program. JAMA Psychiatry. 2022 Sep 1;79(9):898-906. doi: 10.1001/jamapsychiatry.2022.1973. PMID: 35895053; PMCID: PMC9330278.

Lee PH, Doyle AE, Silberstein M, Jung JY, Liu R, Perlis RH, Roffman J, Smoller JW, Fava M, Kessler RC. Associations Between Genetic Risk for Adult Suicide Attempt and Suicidal Behaviors in Young Children in the US. JAMA Psychiatry. 2022 Aug 31:e222379. doi: 10.1001/jamapsychiatry.2022.2379. Epub ahead of print. PMID: 36044238; PMCID: PMC9434482.

Boutin NT, Schecter SB, Perez EF, Tchamitchian NS, Cerretani XR, Gainer VS, Lebo MS, Mahanta LM, Karlson EW, Smoller JW. The Evolution of a Large Biobank at Mass General Brigham. J Pers Med. 2022 Aug 17;12(8):1323. doi: 10.3390/jpm12081323. PMID: 36013271; PMCID: PMC9410531.

Nesi J, Burke TA, Caltabiano A, Spirito A, Wolff JC. Digital media-related precursors to psychiatric hospitalization among youth. J Affect Disord. 2022 Aug 1;310:235-240. doi: 10.1016/j.jad.2022.05.013. Epub 2022 May 6. PMID: 35533775.

Burke TA, Domoff SE, Croarkin PE, Romanowicz M, Borgen A, Wolff J, Nesi J. Reactions to naturalistic smartphone deprivation among psychiatrically hospitalized adolescents. J Psychiatr Res. 2022 Aug 1;155:17-23. doi: 10.1016/j.jpsychires.2022.07.061. Epub ahead of print. PMID: 35977433.

Choi KW
, Wilson M, Ge T, Kandola A, Patel CJ, Lee SH, Smoller JW. Integrative analysis of genomic and exposomic influences on youth mental health. J Child Psychol Psychiatry. 2022 Aug 10. doi: 10.1111/jcpp.13664. Epub ahead of print. PMID: 35946823.

Liu RT, Walsh RFL, Sheehan AE, Cheek SM, Sanzari CM. Prevalence and Correlates of Suicide and Nonsuicidal Self-injury in Children: A Systematic Review and Meta-analysis. JAMA Psychiatry. 2022 Jul 1;79(7):718-726. doi: 10.1001/jamapsychiatry.2022.1256. PMID: 35612875; PMCID: PMC9134039.

Koh, K. A., Montgomery, A. E., O'Brien, R. W., Kennedy, C. J., Luedtke, A., Sampson, N. A., ... & Kessler, R. C. (2022). Predicting Homelessness Among US Army Soldiers No Longer on Active Duty. American Journal of Preventive Medicine, in press.

Ge T, Irvin MR, Patki A, Srinivasasainagendra V, Lin YF, Tiwari HK, Armstrong ND, Benoit B, Chen CY, Choi KW, Cimino JJ, Davis BH, Dikilitas O, Etheridge B, Feng YA, Gainer V, Huang H, Jarvik GP, Kachulis C, Kenny EE, Khan A, Kiryluk K, Kottyan L, Kullo IJ, Lange C, Lennon N, Leong A, Malolepsza E, Miles AD, Murphy S, Namjou B, Narayan R, O'Connor MJ, Pacheco JA, Perez E, Rasmussen-Torvik LJ, Rosenthal EA, Schaid D, Stamou M, Udler MS, Wei WQ, Weiss ST, Ng MCY, Smoller JW, Lebo MS, Meigs JB, Limdi NA, Karlson EW. Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations. Genome Med. 2022 Jun 29;14(1):70. doi: 10.1186/s13073-022-01074-2. PMID: 35765100; PMCID: PMC9241245.

Sachdeva, P. S., Barreto, R., von Vacano, C., & Kennedy, C. J. (2022). Assessing Annotator Identity Sensitivity via Item Response Theory: A Case Study in a Hate Speech Corpus. In 2022 ACM Conference on Fairness, Accountability, and Transparency (pp. 1585-1603).

Kennedy, C. J., Marwaha, J. S., Beaulieu-Jones, B. R., Scalise, P. N., Robinson, K. A., Booth, B., ... & Brat, G. A. (2022). Machine learning nonresponse adjustment of patient-reported opioid consumption data to enable consumption-informed postoperative opioid prescribing guidelines. Surgery in Practice and Science, 100098.

Burke TA, Hamilton JL, Seigel D, Kautz M, Liu RT, Alloy LB, Barker DH. Sleep irregularity and nonsuicidal self-injurious urges and behaviors. Sleep. 2022 Jun 13;45(6):zsac084. doi: 10.1093/sleep/zsac084. PMID: 35397476; PMCID: PMC9189944.

Liu RT, Walsh RFL, Sheehan AE, Cheek SM, Sanzari CM. Prevalence and Correlates of Suicide and Nonsuicidal Self-injury in Children: A Systematic Review and Meta-analysis. JAMA Psychiatry. 2022 May 25:e221256. doi: 10.1001/jamapsychiatry.2022.1256. Epub ahead of print. PMID: 35612875; PMCID: PMC9134039.

Choi KW, Lee YH, Liu Z, Fatori D, Bauermeister JR, Luh RA, Clark CR, Brunoni AR, Bauermeister S, Smoller JW. Effects of social support on depression risk during the COVID-19 pandemic: What support types and for whom? medRxiv [Preprint]. 2022 May 16:2022.05.15.22274976. doi: 10.1101/2022.05.15.22274976. PMID: 35611337; PMCID: PMC9128784.

Ruan, Y., Lin, YF., Feng, YC.A. et al. Improving polygenic prediction in ancestrally diverse populations. Nat Genet 54, 573–580 (2022).

Grotzinger AD, Mallard TT, Akingbuwa WA, Ip HF, Adams MJ, Lewis CM, McIntosh AM, Grove J, Dalsgaard S, Lesch KP, Strom N, Meier SM, Mattheisen M, Børglum AD, Mors O, Breen G; iPSYCH; Tourette Syndrome and Obsessive Compulsive Disorder Working Group of the Psychiatric Genetics Consortium; Bipolar Disorder Working Group of the Psychiatric Genetics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genetics Consortium; Schizophrenia Working Group of the Psychiatric Genetics Consortium, Lee PH, Kendler KS, Smoller JW, Tucker-Drob EM, Nivard MG. Genetic architecture of 11 major psychiatric disorders at biobehavioral, functional genomic and molecular genetic levels of analysis. Nat Genet. 2022 May;54(5):548-559. doi: 10.1038/s41588-022-01057-4. Epub 2022 May 5. PMID: 35513722; PMCID: PMC9117465.

Choi KW, Denckla CA, Hoffman N, Budree S, Goddard L, Zar HJ, Stern M, Stein DJ. Influence of Maternal Childhood Trauma on Perinatal Depression, Observed Mother-Infant Interactions, and Child Growth. Matern Child Health J. 2022 Aug;26(8):1649-1656. doi: 10.1007/s10995-022-03417-2. Epub 2022 May 5. PMID: 35508679.

Smoller JW. What can genetics tell us about the schizophrenia construct? Schizophr Res. 2022 Apr;242:126-129. doi: 10.1016/j.schres.2021.12.008. Epub 2022 Feb 4. PMID: 35125284.

Mealer RG, Williams SE, Noel M, Yang B, D'Souza AK, Nakata T, Graham DB, Creasey EA, Cetinbas M, Sadreyev RI, Scolnick EM, Woo CM, Smoller JW, Xavier RJ, Cummings RD. The schizophrenia-associated variant in SLC39A8 alters protein glycosylation in the mouse brain. Mol Psychiatry. 2022 Mar;27(3):1405-1415. doi: 10.1038/s41380-022-01490-1. Epub 2022 Mar 8. PMID: 35260802; PMCID: PMC9106890.

Bentley KH, Zuromski KL, Fortgang RGMadsen EM, Kessler D, Lee H, Nock MK, Reis BY, Castro VM, Smoller JW. Implementing Machine Learning Models for Suicide Risk Prediction in Clinical Practice: Focus Group Study With Hospital Providers. JMIR Form Res. 2022 Mar 11;6(3):e30946. doi: 10.2196/30946. PMID: 35275075; PMCID: PMC8956996.

Williams SE, Noel M, Lehoux S, Cetinbas M, Xavier RJ, Sadreyev RI, Scolnick EM, Smoller JW, Cummings RD, Mealer RG. Mammalian brain glycoproteins exhibit diminished glycan complexity compared to other tissues. Nat Commun. 2022 Jan 12;13(1):275. doi: 10.1038/s41467-021-27781-9. PMID: 35022400; PMCID: PMC8755730.



Burke TA, Bettis AH, Barnicle SC, Wang SB, Fox KR. Disclosure of Self-Injurious Thoughts and Behaviors Across Sexual and Gender Identities. Pediatrics. 2021 Oct;148(4):e2021050255. doi: 10.1542/peds.2021-050255. Epub 2021 Sep 14. PMID: 34521728; PMCID: PMC9115868.

Lawrence HR, Burke TA, Sheehan AE, Pastro B, Levin RY, Walsh RFL, Bettis AH, Liu RT. Prevalence and correlates of suicidal ideation and suicide attempts in preadolescent children: A US population-based study. Transl Psychiatry. 2021 Sep 22;11(1):489. doi: 10.1038/s41398-021-01593-3. PMID: 34552053; PMCID: PMC8458398.

Burke TA, Allen KJD, Carpenter RW, Siegel DM, Kautz MM, Liu RT, Alloy LB. Emotional response inhibition to self-harm stimuli interacts with momentary negative affect to predict nonsuicidal self-injury urges. Behav Res Ther. 2021 Jul;142:103865. doi: 10.1016/j.brat.2021.103865. Epub 2021 Apr 18. PMID: 33940222; PMCID: PMC8523023.

Liu RT. The epidemiology of non-suicidal self-injury: lifetime prevalence, sociodemographic and clinical correlates, and treatment use in a nationally representative sample of adults in England. Psychol Med. 2021 May 7:1-9. doi: 10.1017/S003329172100146X. Epub ahead of print. PMID: 33960286.