Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
33 results
  • Colorectal Cancer, Lung Cancer, Pancreatic Cancer

25-110          Phase I

3263-001: A Phase 1/1b Multiple Cohort Trial of ALTA3263 in Patients With Advanced Solid Tumors With KRAS Mutations

  • Pancreatic Cancer, Ovarian Cancer, Liver Cancer, Breast Cancer, Colorectal Cancer, Esophageal Cancer, Gastric (Stomach) Cancer

25-747          Phase I

A Dose Escalation and Dose Optimization Phase 1a/1b Study to Evaluate Safety, Tolerability and Dosimetry of Radioligand Therapy with LY4337713 in Adults with FAP-Positive Solid Tumors (FiREBOLT)

  • Gastric (Stomach) Cancer, Pancreatic Cancer, Gallbladder and Bile Duct Cancers, Lung Cancer, Liver Cancer, Colorectal Cancer, Endometrial Cancer

26-175          Phase I

A First-in-Human Phase 1 Dose-Escalation Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KST-6051 in Patients With Advanced or Metastatic Solid Tumors With a KRAS Mutation

  • Melanoma, Pancreatic Cancer, Colorectal Cancer, Leukemia, Lung Cancer

26-113          Phase I

A First-in-human Study of RLY-8161 for Treatment of Advanced NRAS-Mutant Melanoma and Other Solid Tumors

  • Colorectal Cancer

24-643          Phase II

A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

  • Prostate Cancer, Colorectal Cancer, Esophageal Cancer, Sarcoma, Bladder Cancer, Pancreatic Cancer, Head and Neck Cancer

25-464          Phase I

A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of GSK5764227 in Participants with Advanced Solid Tumors

  • Head and Neck Cancer, Cervical Cancer, Bladder Cancer, Endometrial Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Pancreatic Cancer, Lung Cancer, Colorectal Cancer

25-816          Phase I

A Phase 1 Open-Label Study to Evaluate Safety, Pharmacokinetics, and Preliminary anti-Tumor Activity of STRO-004 in Adults with Refractory/Recurrent Metastatic Solid Tumors

  • Colorectal Cancer, Prostate Cancer, Lung Cancer

25-695          Phase I

A Phase 1 Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors

  • Prostate Cancer, Lung Cancer, Colorectal Cancer, Breast Cancer, Bladder Cancer

23-452          Phase I

A Phase 1, First-in-Human, Dose Escalation and Expansion Study of FX-909 in Patients with Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

  • Pancreatic Cancer, Lung Cancer, Colorectal Cancer

25-022          Phase I

A Phase 1, Open-Label Dose Escalation and Expansion Study of PT0253 in Participants with KRAS G12D Mutated Advanced Solid Tumors

Showing 1 - 10 of 33 results