Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
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37 results
  • Pancreatic Cancer, Lung Cancer, Colorectal Cancer

25-110          Phase I

3263-001: A Phase 1/1b Multiple Cohort Trial of ALTA3263 in Patients With Advanced Solid Tumors With KRAS Mutations

  • Ovarian Cancer, Liver Cancer, Breast Cancer, Esophageal Cancer, Pancreatic Cancer, Gastric (Stomach) Cancer, Colorectal Cancer

25-747          Phase I

A Dose Escalation and Dose Optimization Phase 1a/1b Study to Evaluate Safety, Tolerability and Dosimetry of Radioligand Therapy with LY4337713 in Adults with FAP-Positive Solid Tumors (FiREBOLT)

  • Pancreatic Cancer, Colorectal Cancer, Liver Cancer, Endometrial Cancer, Gastric (Stomach) Cancer, Lung Cancer, Gallbladder and Bile Duct Cancers

26-175          Phase I

A First-in-Human Phase 1 Dose-Escalation Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KST-6051 in Patients With Advanced or Metastatic Solid Tumors With a KRAS Mutation

  • Pancreatic Cancer, Melanoma, Lung Cancer, Colorectal Cancer, Leukemia

26-113          Phase I

A First-in-human Study of RLY-8161 for Treatment of Advanced NRAS-Mutant Melanoma and Other Solid Tumors

  • Colorectal Cancer

24-643          Phase II

A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

  • Bladder Cancer, Sarcoma, Prostate Cancer, Pancreatic Cancer, Head and Neck Cancer, Esophageal Cancer, Colorectal Cancer

25-464          Phase I

A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of GSK5764227 in Participants with Advanced Solid Tumors

  • Thyroid Cancer, Pancreatic Cancer, Lung Cancer, Colorectal Cancer

26-272          Phase I

A Phase 1 First-in-human Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of ERAS-0015 Monotherapy and in Combination in Patients with Advanced Solid Tumors

  • Gastric (Stomach) Cancer, Head and Neck Cancer, Lung Cancer, Pancreatic Cancer, Colorectal Cancer, Endometrial Cancer, Bladder Cancer, Esophageal Cancer, Cervical Cancer

25-816          Phase I

A Phase 1 Open-Label Study to Evaluate Safety, Pharmacokinetics, and Preliminary anti-Tumor Activity of STRO-004 in Adults with Refractory/Recurrent Metastatic Solid Tumors

  • Colorectal Cancer, Prostate Cancer, Lung Cancer

25-695          Phase I

A Phase 1 Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors

  • Colorectal Cancer, Prostate Cancer, Bladder Cancer, Breast Cancer, Lung Cancer

23-452          Phase I

A Phase 1, First-in-Human, Dose Escalation and Expansion Study of FX-909 in Patients with Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

Showing 1 - 10 of 37 results