Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
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31 results
  • Colorectal Cancer, Lung Cancer, Pancreatic Cancer

25-110          Phase I

3263-001: A Phase 1/1b Multiple Cohort Trial of ALTA3263 in Patients With Advanced Solid Tumors With KRAS Mutations

  • Liver Cancer, Ovarian Cancer, Pancreatic Cancer, Breast Cancer, Colorectal Cancer, Esophageal Cancer, Gastric (Stomach) Cancer

25-747          Phase I

A Dose Escalation and Dose Optimization Phase 1a/1b Study to Evaluate Safety, Tolerability and Dosimetry of Radioligand Therapy with LY4337713 in Adults with FAP-Positive Solid Tumors (FiREBOLT)

  • Colorectal Cancer

24-643          Phase II

A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

  • Head and Neck Cancer, Bladder Cancer, Sarcoma, Prostate Cancer, Pancreatic Cancer, Esophageal Cancer, Colorectal Cancer

25-464          Phase I

A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of GSK5764227 in Participants with Advanced Solid Tumors

  • Bladder Cancer, Cervical Cancer, Colorectal Cancer, Lung Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Head and Neck Cancer, Endometrial Cancer, Pancreatic Cancer

25-816          Phase I

A Phase 1 Open-Label Study to Evaluate Safety, Pharmacokinetics, and Preliminary anti-Tumor Activity of STRO-004 in Adults with Refractory/Recurrent Metastatic Solid Tumors

  • Colorectal Cancer, Lung Cancer, Prostate Cancer

25-695          Phase I

A Phase 1 Study of XB628 in Participants With Recurrent Advanced or Metastatic Solid Tumors

  • Prostate Cancer, Lung Cancer, Colorectal Cancer, Breast Cancer, Bladder Cancer

23-452          Phase I

A Phase 1, First-in-Human, Dose Escalation and Expansion Study of FX-909 in Patients with Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

  • Lung Cancer, Colorectal Cancer, Pancreatic Cancer

25-022          Phase I

A Phase 1, Open-Label Dose Escalation and Expansion Study of PT0253 in Participants with KRAS G12D Mutated Advanced Solid Tumors

  • Colorectal Cancer, Lung Cancer, Pancreatic Cancer

25-812          Phase I

A Phase 1, Open-Label Dose Escalation and Expansion Study of PT0511 in Participants with KRAS Mutated or Amplified Advanced Solid Tumors

  • Prostate Cancer, Pancreatic Cancer, Ovarian Cancer, Melanoma, Lung Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Esophageal Cancer, Colorectal Cancer, Cervical Cancer, Breast Cancer, Bladder Cancer

25-287          Phase I

A Phase 1, Open-label, Multi-center Study of the Safety, Tolerability, and Efficacy of IPH4502 as a Single Agent in Advanced Solid Tumors

Showing 1 - 10 of 31 results