Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
11 results
  • Ovarian Cancer, Gastric (Stomach) Cancer, Sarcoma

24-169          Phase I

A Molecularly Driven Phase 1b Dose Escalation and Dose Expansion Study of the DNA-PK Inhibitor Peposertib (M3814) in Combination with the ATR Inhibitor M1774

  • Pancreatic Cancer, Esophageal Cancer, Gastric (Stomach) Cancer

21-385          Phase I

A PHASE 1 STUDY OF TJ033721 IN SUBJECTS WITH ADVANCED OR METASTATIC SOLID TUMORS

  • Prostate Cancer, Pancreatic Cancer, Melanoma, Lung Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Esophageal Cancer, Colorectal Cancer, Cervical Cancer, Breast Cancer, Bladder Cancer, Ovarian Cancer

25-287          Phase I

A Phase 1, Open-label, Multi-center Study of the Safety, Tolerability, and Efficacy of IPH4502 as a Single Agent in Advanced Solid Tumors

  • Pancreatic Cancer, Bladder Cancer, Endometrial Cancer, Esophageal Cancer, Sarcoma, Liver Cancer, Gastric (Stomach) Cancer

20-544          Phase II

A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation

  • Gastric (Stomach) Cancer, Lung Cancer, Colorectal Cancer

23-340          Phase II

A Phase 1/2 Study of FOG-001 in Participants with Locally Advanced or Metastatic Solid Tumors

  • Lung Cancer, Kidney Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Bladder Cancer, Pancreatic Cancer, Esophageal Cancer, Cervical Cancer, Colorectal Cancer

25-448          Phase II

A Phase 1/2 Study of GEN1286 in Patients with Advanced Solid Tumors

  • Thymoma, Ovarian Cancer, Melanoma, Lung Cancer, Kidney Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Rectal Cancer, Esophageal Cancer, Colorectal Cancer

23-423          Phase I

A Phase I, Open-label, Multi-center Study of KFA115 as a Single Agent and in Combination with Pembrolizumab in Patients with Select Advanced Cancers

  • Esophageal Cancer, Gastric (Stomach) Cancer

24-486          Phase III

A Phase III Multi-center, Open-label, Sponsor-blinded, Randomized Study of AZD0901 Monotherapy Compared with Investigator’s Choice of Therapy in Second- or Later-Line Adult Participants with Advanced/Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

  • Esophageal Cancer, Gastric (Stomach) Cancer

24-242          Phase II

A Single-Arm, Multicenter Phase 2 Study of Neoadjuvant Pembrolizumab with Trastuzumab and Chemotherapy in Resectable HER2+ Esophagogastric Tumors

  • Metastatic/Advanced Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Endometrial Cancer, Colorectal Cancer, Cervical Cancer, Breast Cancer, Ovarian Cancer

23-618          Phase I

A Study to Evaluate the Safety and Tolerability of the Covalent Phosphoinositide-3-Kinase (PI3K)-alpha Inhibitor, TOS-358, in Adult Subjects with Select Solid Tumors

Showing 1 - 10 of 11 results