Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
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18 results
  • Pancreatic Cancer, Breast Cancer, Colorectal Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Liver Cancer, Ovarian Cancer

25-747          Phase I

A Dose Escalation and Dose Optimization Phase 1a/1b Study to Evaluate Safety, Tolerability and Dosimetry of Radioligand Therapy with LY4337713 in Adults with FAP-Positive Solid Tumors (FiREBOLT)

  • Endometrial Cancer, Gastric (Stomach) Cancer, Lung Cancer, Gallbladder and Bile Duct Cancers, Pancreatic Cancer, Liver Cancer, Colorectal Cancer

26-175          Phase I

A First-in-Human Phase 1 Dose-Escalation Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KST-6051 in Patients With Advanced or Metastatic Solid Tumors With a KRAS Mutation

  • Gastric (Stomach) Cancer, Ovarian Cancer, Sarcoma

24-169          Phase I

A Molecularly Driven Phase 1b Dose Escalation and Dose Expansion Study of the DNA-PK Inhibitor Peposertib (M3814) in Combination with the ATR Inhibitor M1774

  • Endometrial Cancer, Pancreatic Cancer, Colorectal Cancer, Cervical Cancer, Lung Cancer, Bladder Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Head and Neck Cancer

25-816          Phase I

A Phase 1 Open-Label Study to Evaluate Safety, Pharmacokinetics, and Preliminary anti-Tumor Activity of STRO-004 in Adults with Refractory/Recurrent Metastatic Solid Tumors

  • Gastric (Stomach) Cancer, Esophageal Cancer, Pancreatic Cancer

21-385          Phase I

A PHASE 1 STUDY OF TJ033721 IN SUBJECTS WITH ADVANCED OR METASTATIC SOLID TUMORS

  • Melanoma, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer, Bladder Cancer, Breast Cancer, Cervical Cancer, Colorectal Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Head and Neck Cancer, Lung Cancer

25-287          Phase I

A Phase 1, Open-label, Multi-center Study of the Safety, Tolerability, and Efficacy of IPH4502 as a Single Agent in Advanced Solid Tumors

  • Endometrial Cancer, Bladder Cancer, Esophageal Cancer, Gastric (Stomach) Cancer, Liver Cancer, Sarcoma, Pancreatic Cancer

20-544          Phase II

A Phase 1/2 Open-label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of PC14586 in Patients with Advanced Solid Tumors Harboring a p53 Y220C Mutation

  • Colorectal Cancer, Gastric (Stomach) Cancer, Lung Cancer

23-340          Phase II

A Phase 1/2 Study of FOG-001 in Participants with Locally Advanced or Metastatic Solid Tumors

  • Breast Cancer, Metastatic/Advanced Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Cervical Cancer

25-075          Phase II

A Phase 1/2, Open-label, Global, Multicenter, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Combination with Pembrolizumab in Participants with Advanced Solid Tumors

  • Lung Cancer, Head and Neck Cancer, Gastric (Stomach) Cancer, Ovarian Cancer, Cervical Cancer, Endometrial Cancer, Esophageal Cancer, Breast Cancer

26-124          Phase I

A Phase 1a/1b Study of NRM-823 as Monotherapy and in Combination with Immune Checkpoint Inhibition in Participants with Locally Advanced or Metastatic Refractory Solid Tumors

Showing 1 - 10 of 18 results