Search Cancer Clinical Trials

Mass General Brigham Cancer Institute offers patients access to a wide variety of clinical trials of promising new therapies. Use the search tool to find open protocols for your type of cancer.
31 results
  • Pancreatic Cancer, Lung Cancer, Colorectal Cancer

25-110          Phase I

3263-001: A Phase 1/1b Multiple Cohort Trial of ALTA3263 in Patients With Advanced Solid Tumors With KRAS Mutations

  • Ovarian Cancer, Liver Cancer, Breast Cancer, Esophageal Cancer, Pancreatic Cancer, Gastric (Stomach) Cancer, Colorectal Cancer

25-747          Phase I

A Dose Escalation and Dose Optimization Phase 1a/1b Study to Evaluate Safety, Tolerability and Dosimetry of Radioligand Therapy with LY4337713 in Adults with FAP-Positive Solid Tumors (FiREBOLT)

  • Pancreatic Cancer, Colorectal Cancer, Liver Cancer, Endometrial Cancer, Gastric (Stomach) Cancer, Lung Cancer, Gallbladder and Bile Duct Cancers

26-175          Phase I

A First-in-Human Phase 1 Dose-Escalation Study Evaluating the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of KST-6051 in Patients With Advanced or Metastatic Solid Tumors With a KRAS Mutation

  • Pancreatic Cancer, Melanoma, Lung Cancer, Colorectal Cancer, Leukemia

26-113          Phase I

A First-in-human Study of RLY-8161 for Treatment of Advanced NRAS-Mutant Melanoma and Other Solid Tumors

  • Ovarian Cancer, Lung Cancer, Sarcoma, Breast Cancer, Kidney Cancer, Head and Neck Cancer, Liver Cancer, Pancreatic Cancer, Thyroid Cancer

23-301          Phase I

A First-in-Human, Open-label, Multicenter, Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of PYX-201 in Participants with Advanced Solid Tumors

  • Bladder Cancer, Sarcoma, Prostate Cancer, Pancreatic Cancer, Head and Neck Cancer, Esophageal Cancer, Colorectal Cancer

25-464          Phase I

A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of GSK5764227 in Participants with Advanced Solid Tumors

  • Thyroid Cancer, Pancreatic Cancer, Lung Cancer, Colorectal Cancer

26-272          Phase I

A Phase 1 First-in-human Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of ERAS-0015 Monotherapy and in Combination in Patients with Advanced Solid Tumors

  • Gastric (Stomach) Cancer, Head and Neck Cancer, Lung Cancer, Pancreatic Cancer, Colorectal Cancer, Endometrial Cancer, Bladder Cancer, Esophageal Cancer, Cervical Cancer

25-816          Phase I

A Phase 1 Open-Label Study to Evaluate Safety, Pharmacokinetics, and Preliminary anti-Tumor Activity of STRO-004 in Adults with Refractory/Recurrent Metastatic Solid Tumors

  • Esophageal Cancer, Pancreatic Cancer, Gastric (Stomach) Cancer

21-385          Phase I

A PHASE 1 STUDY OF TJ033721 IN SUBJECTS WITH ADVANCED OR METASTATIC SOLID TUMORS

  • Pancreatic Cancer

25-131          Phase I

A Phase 1, First-in-Human, Open Label, Dose Escalation and Cohort Expansion Study of MGC028 in Participants with Advanced Solid Tumors

Showing 1 - 10 of 31 results