Lauren Corduck and her father Bob Cooperstein speak about how their lives have been impacted by having tested positive for a BRCA gene mutation.
Breast and Ovarian Cancer Genetics Clinic
55 Fruit Street, YAW 10B
Boston, MA 02114
If you are interested in a consultation with the Breast and Ovarian Cancer Risk Assessment team, you can make an appointment at one of four locations:
- Mass General Cancer Center main campus (Yawkey Building, Suite 10B, 55 Fruit St., Boston); call 617-724-1971
- Mass General/North Shore Cancer Center (102 Endicott St., Danvers, MA); call 978-882-6370
- Mass General Cancer Center at Emerson Hospital – Bethke (133 Old Road to Nine Acre Corner, Concord, MA); call 978-371-4805
- Mass General Waltham (52 Second Ave., Suite 1110, Waltham, MA 02451); call 781-487-6100
Explore the Breast and Ovarian Cancer Genetics Clinic
The Breast and Ovarian Cancer Genetics Clinic was the first disease program established within the Center for Cancer Risk Assessment (CCRA). Under the direction of Leif W. Ellisen, MD, PhD, our staff includes specialists in both breast oncology and genetics. We also work closely with the gynecology/oncology group at Massachusetts General Hospital.
Patients interested in an evaluation for hereditary breast or ovarian cancer meet first with a genetic counselor. During the initial genetics consultation, family history is carefully reviewed. If your personal or family history suggests a possible genetic risk, we will discuss the option of genetic testing.
Each patient's history is reviewed with Dr. Ellisen and the Breast and Ovarian Cancer Genetics team. When appropriate, we will make medical management recommendations. If you are identified as high-risk based on genetic testing and/or family history, you can choose to be followed by one of our high-risk specialists, Drs. Ellisen and Micalizzi, or other members of the high-risk team at the Mass General Cancer Center.
Should You Consider Genetic Counseling?
A visit to our clinic may be appropriate if you have a personal or family history of one or more of the following:
- Breast cancer diagnosed before age 45
- Breast cancer in three or more people on one side (maternal or paternal) of the family
- Bilateral breast cancer diagnosis
- Breast cancer in an individual of Ashkenazi Jewish descent
- Ovarian cancer
- Family history of:
- Breast and ovarian cancer
- Breast, thyroid and uterine cancer
- Breast, sarcoma, leukemia, adrenal cortical cancer and brain cancer
- Breast cancer and diffuse gastric cancer
- Breast and pancreatic cancer
Hereditary Breast/Ovarian Cancer Diseases
The conditions most commonly discussed with patients in our clinic include:
- Hereditary breast and ovarian cancer syndrome (BRCA1/2 genes)
- Li-Fraumeni syndrome (TP53 gene)
- Cowden syndrome, also known at PTEN-hamartoma tumor syndrome (PTEN gene)
- Hereditary diffuse gastric cancer syndrome (CDH1 gene)
Patient Education and Resources