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Dr. Kinane in pediatric pulmonologist who is an international expert in pediatric respiratory conditions.
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MassGeneral Hospital for Children
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Dr. Kinane graduated from University College Dublin in 1983 with an MB. He completed Pediatric Residencies in Dublin (1987) and at the University of Texas South Western Medical School (1989). Following the completion of a Pediatric Pulmonary Fellowship at the Massachusetts General Hospital in 1992, he joined the faculty. He was appointed Chief of Pediatric Pulmonary (2000). In addition, he holds a number of leadership positions including Associate Chief for Education and Director of the Pediatric Sleep Program.Since joining the faculty, Dr. Kinane has provided cutting edge clinical care to patients with a variety of pulmonary conditions including asthma, interstitial lung disease, sleep disorders, pneumonia, primary ciliary dyskinesia and pulmonary congenital abnormalities. He is seen as a International Expert on the genetic basis and treatment of interstitial lung disease, lung developmental abnormalities and the regulation of breathing.His research focuses on the basic cause of interstitial lung disease and asthma. His sleep research focuses on the regulation of respiration and safe transportation of infants in car seats. Dr. Kinane is also committed to the education of medical students, trainees and patients. He has won numerous teaching awards since joining the faculty. He has a particular focus on the use of social media to educate teenagers about a healthy lifestyle and asthma management.
Dr. Kinane's research focuses on 3 distinct areas:Regulation of cell migration:- Dr. Kinane's group focuses on transduction pathways that regulate cell migration and lung development. He has identified novel regulators of lung cell and inflammatory migration including Netrins. He found that these Netrin like molecules are critical in regulation of lung development and inflammatory responses. This research has broad implications for congenital lung malformation, blood vessel inflammation including coronary artery disease and autoimmune disease. Regulation of the control of breathing:- In patients with central congenital hypoventilation syndrome, his group identified one of the molecular mechanisms of this syndrome. Recently he has extended this work to the regulation of breathing in common physiological conditions. He has recently focused his studies on airway obstruction in infants while placed in a car seat. This work has resulted in a number of highly cited manuscripts.
Pediatric interstitial lung disease:- Dr. Kinane's group works on the genetic basis, classification and treatment of interstitial disease. He has developed a genetics clinic in pulmonary to support this work.
At 5 weeks old, Natalia Boidi was rushed to the emergency room where doctors diagnosed her with SMA, a rare genetic disorder in which the nerves in the spinal cord slowly die off. After months in the PICU and a novel treatment called Spinraza, Natalia can breathe on her own and is learning to stand - things that were once almost impossible with her disease.
Education is central to the mission of MassGeneral Hospital for Children. The education mission stretches the spectrum from medical students to residents to fellows to faculty. Indeed some of the techniques used to teach these medical learners are now used in pediatric patient education.
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