About Thomas Kinane, MD

Dr. Kinane graduated from University College Dublin in 1983 with an MB. He completed Pediatric Residencies in Dublin (1987) and at the University of Texas South Western Medical School (1989). Following the completion of a Pediatric Pulmonary Fellowship at the Massachusetts General Hospital in 1992, he joined the faculty. He was appointed Chief of Pediatric Pulmonary (2000).  In addition, he holds a number of leadership positions including Associate Chief for Education and Director of the Pediatric Sleep Program.

Since joining the faculty, Dr. Kinane has provided cutting edge clinical care to patients with a variety of pulmonary conditions including asthma, interstitial lung disease, sleep disorders, pneumonia, primary ciliary dyskinesia and pulmonary congenital abnormalities. He is seen as a International Expert on the genetic basis and treatment of interstitial lung disease, lung developmental abnormalities and the regulation of breathing.

His research focuses on the basic cause of interstitial lung disease and asthma.  His sleep research focuses on the regulation of respiration and safe transportation of infants in car seats.

Dr. Kinane is also committed to the education of medical students, trainees and patients.  He has won numerous teaching awards since joining the faculty.  He has a particular focus on the use of social media to educate teenagers about a healthy lifestyle and asthma management.

Clinical Interests:

Treats:

Locations

Pediatric Pulmonary
275 Cambridge Street
POB 275
Boston, MA 02114
617-726-8707
Fax: 617-724-2803

Pediatric Sleep Lab
55 Fruit Street
Warren 905
Boston, MA 02114-2696
617-643-4454
Fax: 617-643-4462

Administrative Office
5th Floor
175 Cambridge Street
Boston, Ma 02481
617-724-2893

Medical Education

  • MD, University College Dublin School of Medicine
  • Residency, Children's Medical Center
  • Residency, Our Lady Hospital for Sick Children
  • Fellowship, Massachusetts General Hospital

American Board Certifications

  • Pediatric Pulmonology, American Board of Pediatrics
  • Sleep Medicine, American Board of Internal Medicine

Accepted Insurance Plans

Note: This provider may accept more insurance plans than shown; please call the practice to find out if your plan is accepted.


Research

Dr. Kinane's research focuses on 3 distinct areas:

Regulation of cell migration:-
Dr. Kinane's group focuses on transduction pathways that regulate cell migration and lung development.  He has identified novel regulators of lung cell and inflammatory migration including Netrins. He found that these Netrin like molecules are critical in regulation of lung development and inflammatory responses. This research has broad implications for congenital lung malformation, blood vessel inflammation including coronary artery disease and autoimmune disease. 

Regulation of the control of breathing:-
In patients with central congenital hypoventilation syndrome, his group identified one of the molecular mechanisms of this syndrome. Recently he has extended this work to the regulation of breathing in common physiological conditions.  He has recently focused his studies on airway obstruction in infants while placed in a car seat. This work has resulted in a number of highly cited manuscripts. 

Pediatric interstitial lung disease:- Dr. Kinane's group works on the genetic basis, classification and treatment of interstitial disease. He has developed a genetics clinic in pulmonary to support this work.

Publications

    1. Kinane TB. Lung development and implications for hypoplasia found in congenital diaphragmatic hernia. Am J Med Genet C Semin Med Genet (2007); 145(2): 117-24.
    2. Canapari CA, Hoppin AG, Kinane TB, Thomas BJ, Torriani M, Katz ES.(2011) Relationship between Sleep Apnea, Fat Distribution, and Insulin Resistance in Obese Children. J Clin Sleep Med 7(3):268-273
    3. Yonker LM, Kinane TB. Pediatric interstitial lung disease: TTF-1 mutations and their phenotype potpourri  Chest 2013 Sep;144(3):728-30
    4. Yonker LM, Zan S, Scirica CV, Jethwani K, Kinane TB . "Friending" Teens:Systematic Review of Social Media in Adolescent and Young Adult Health Care. J Med Internet Res. 2015 Jan 5;17(1):e4.
    5. Diercks GR, Keamy D, Kinane TB, Skotko B, Schwartz A, Grealish E, Dobrowski J,Soose R, Hartnick CJ. Hypoglossal Nerve Stimulator Implantation in an Adolescent With Down Syndrome and Sleep Apnea. Pediatrics. 2016 May;137(5).
    6. Denman LA, Yonker LM, Kinane TB. The Classification of ATP-binding Cassette Subfamily A Member 3 (ABCA3) Mutations Using The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Classification System. In Press Pediatric Investigation
    7. Kinane TB, Mayer OH, Duda PW, Lowes LP, Moody SL, Mendell JR Long- Term Pulmonary Function In Patients with Duchenne Muscular Dystrophy: Comparison of Eteplirsen-Treated Patients to Natural History. J Neuromuscul Dis. 2017 Dec 20. doi: 10.3233/JND-170272