“Weekend Warrior” Physical Activity Provides Similar Heart-Related Benefits As More Regular Exercise
Study results suggest that engaging in some physical activity, regardless of pattern, helps protect against a range of cardiovascular conditions.
Corrigan Minehan Heart Center
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Structural heart diseases encompass defects and disorders that affect the structure of the heart. Often, these diseases are present from birth (congenital), but they can also develop later in life. Our clinical and translational research efforts broadly seek to improve the clinical diagnosis and management of patients with structural and adult congenital heart diseases. Much of our research specifically targets the development and improvement of minimally invasive, catheter-based procedures to treat structural and adult congenital heart diseases and translational research studies to expand our understanding of the natural history and biology of these unique diseases.
CORCINCH-HF: Randomized Clinical Evaluation of the AccuCinch® Ventricular Restoration System in Patients who Present with Symptomatic Heart Failure with Reduced Ejection Fraction (HFrEF)
Summary: The purpose of this clinical study is to evaluate the safety and efficacy of the AccuCinch Ventricular Restoration System in patients with heart failure and reduced ejection fraction (HFrEF).
Summary: The intent of the Global cVAD Study is to utilize observational data of hemodynamic support devices in real-world settings to drive best practice usage patterns identified through study analysis.
Novel Markers of Myocardial Injury
Summary: Patients undergoing alcohol septal ablation for hypertrophic cardiomyopathy have blood collected at certain time points for analysis.
Summary: Randomized controlled study of the Occlutech Flex II PFO closure device, compared to Amplatzer or Gore PFO closure devices, in patients with a patent foramen ovale who have suffered from a cryptogenic stroke or transient ischemic attack.
REDUCE PAS: GSO 18-01. GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients with Patent Foramen Ovale (PFO): The REDUCE Post Approval Study
Summary: The REDUCE PAS study is for patients with a history of cryptogenic stroke (stroke of unknown cause) who also have a patent foramen ovale, or a small hole between the two upper chambers of the heart. With a device that is fed up into the heart through vessels in the groin, doctors can close the PFO, which helps prevent future strokes. Gore REDUCE PAS is a post-market approval study, meaning the closure device used in the study has already been approved by the U.S. Food and Drug Administration. The purpose of the research is to continue to collecting data on the device, even after FDA approval, and to learn more about PFO closure.
RELIEF: GORE® CARDIOFORM Septal Occluder Migraine Clinical Study: A Study to Evaluate the Safety and Efficacy of Transcatheter Closure of Patent Foramen Ovale for Relief of Migraine Headaches
Summary: RELIEF is a multi-center, prospective, randomized, placebo- and sham-controlled study to evaluate the GORE® CARDIOFORM Septal Occluder for migraine headache relief in patients with a presence of PFO who experience migraine headaches.
Study results suggest that engaging in some physical activity, regardless of pattern, helps protect against a range of cardiovascular conditions.
The findings could help in identifying new interventions that reduce the brain’s stress activity without the negative health effects of alcohol.
The Heart Transplant Program successfully completed its 750th transplant on Sunday, April 30. Since the hospital’s first heart transplant in 1985, the Heart Transplant Program has grown into the highest annual volume program in New England.
Tips for Caregivers to Maximize a Child’s Heart Health for a Lifetime
The workshop outlined research opportunities to identify and treat patients with mitral valve prolapse (MVP) who are at risk of sudden cardiac arrest and death.
Learn more about our research opportunities and open clinical trials.