There are no distinct patient symptoms, although many patients do present with pathologic fracture. It is important to have blood tests taken to rule out leukemia. Lymphomas of bone are similar to Ewing's sarcoma and on x-ray appear as distinctive lesions not well defined with breakage of the cortex and soft tissue mass. The tumor cells are large and round varying in size and shape. Treatment consists of radiation with surgical fixation of pathologic fractures if necessary, and adjuvant chemotherapy.