Explore This Lab

About the Lab

The Molecular Pathology Unit, located in newly renovated facilities on the 6th and 7th floors of Building 149 in the Charlestown Navy Yard, is the largest research unit of the MGH Pathology Service. The Unit is composed of nine independent investigators and over 60 scientists. Research interests of the PIs range from basic science to translational research with a primary emphasis on cancer biology. Most faculty also have dual appointments with the MGH Cancer Center. We are growing into newly renovated space on the 7th floor of Building 149 and are actively recruiting additional faculty.

Research Projects

Mechanisms Driving Progression and Relapse in Pediatric Tumors

  • Mechanisms of progression and relapse in T-cell acute lymphoblastic leukemia
  • Functional consequences of tumor cell heterogeneity in embryonal rhabdomyosarcoma
  • Optimized cell transplantation using immune compromised fish

Group Members

Meet our research team:
  • David Langenau, PhD, Director
  • Martin Aryee, PhD
  • John Iafrate, MD, PhD
  • J. Keith Joung, MD, PhD
  • David Louis, MD
  • Miguel Rivera, MD
  • Dennis Sgroi, MD
  • Anat Stemmer-Rachamimov, MD
  • Mario Suva, MD, PhD
  • Francesca S. Gazzaniga, Ph.D.