The goal of the Ellisen Lab is to understand transcription factor deregulation as a means to therapeutically target and identify biomarkers of treatment response in a broad spectrum of human cancers.

The p53 Family of Transcription Factors in Development, Cancer Pathogenesis and Development

Leif Ellisen, MD, PhD
Leif Ellisen, MD, PhD
Weissman Family MGH Research Scholar 2014-2019
Physician Investigator, Mass General Cancer Center
Professor of Medicine, Harvard Medical School

I am a basic and translational cancer researcher and practicing medical oncologist at the Massachusetts General Hospital Cancer Center, and an Associate Professor of Medicine at Harvard Medical School. I also direct the breast and ovarian cancer genetics program at Mass General.

The majority of my time is spent on basic research, the goal of which is to understand transcription factor deregulation as a means to therapeutically target and identify biomarkers of treatment response in a broad spectrum of human cancers.

As co-Executive Director of the Translational Research Laboratory (TRL) for tumor molecular profiling at the Mass General Cancer Center, our translational research focuses developing and implementing technologies for tumor molecular analysis to advance the goal of individualized cancer treatment.