MGH Research Scholars Program
The MGH Research Scholars Program was established to support early career researchers with innovative yet unproven ideas that have the potential to transform the future of medicine. Funded 100% through philanthropy, this program gives researchers the freedom and flexibility they need to follow the science wherever it leads. History has shown that brilliant scientists who are given free rein to explore new frontiers make the greatest, often unexpected, advances.
The Talkowski Lab studies the genetics of disorders affecting prenatal, neonatal, and early childhood development, particularly autism spectrum disorder (ASD) and related neurodevelopmental and psychiatric disorders.
Translational Genomics in the Laboratory and in the Clinic
The Talkowski Laboratory is interested in understanding the consequence of genomic variation on human disease.
We study the genetic etiology of disorders affecting prenatal, neonatal, and early childhood development, particularly autism spectrum disorder (ASD) and related neurodevelopmental and psychiatric disorders.
Our research program integrates a molecular genomics wet laboratory with a computational genomics group.
The lab is composed of undergraduate and graduate students, post-baccalaureate researchers, postdoctoral fellows, and senior staff scientists performing human genomic research in four primary domains:
- Delineation of genomic variation and genome biology
- Discovery of genes that can contribute to human disease when altered
- Functional genomic characterization of genetic lesions and the networks that they disrupt
- Translation of genomics technology development into new genetic diagnostic methods