The Alessandrini Lab in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital studies regulatory T cells and plasmacytoid dendritic cells, and the roles they play in the induction of transplantation tolerance.
CTS Research Labs
The Cellular and Molecular Immunology Laboratory in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital studies the immune mechanisms underlying the allorecognition and alloresponse by T and B cells in transplant rejection and tolerance.
The Cardiothoracic Transplantation Lab uses molecular and cellular techniques to study transplantation tolerance, acute/chronic rejection, innate immunity, xenotransplantation and whole organ bioengineering for heart/lung transplantation.
Robert B. Colvin, MD
The Cosimi/Kawai Laboratory focuses on allograft tolerance induction in nonhuman primates and humans, with the goal of developing safe and reliable tolerance-inducing regimens for clinical transplantation.
The Hematopoietic Cell Transplantation Lab studies the immunology of hematopoietic cell transplantation to eliminate immunological barriers in patients with cancers and other diseases that affect the blood, bone marrow and lymph nodes.
The Hoggatt Laboratory focuses on stem cell biology and the development of novel therapies for cancer and tissue regeneration.
The Molecular Biology Laboratory in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital focuses on deciphering the role of major histocompatibility class II molecules in the modulation of T cell responses to self and foreign antigens.
The Markmann Laboratory in the Center for Transplantation Sciences (CTS) at Massachusetts General Hospital examines the hypothesis that a small subset of B cells plays a beneficial or regulatory role in transplant tolerance within the elderly population.
The Laboratory of Richard Pierson, MD, and Agnes Azimzadeh, PhD at Massachusetts General Hospital centers around understanding and preventing the mechanisms of rejected organs through two main research areas: immunomodulation and xenotransplantation.