Center for Cancer Research
Advancing Cancer Research
The mission of the Mass General Center for Cancer Research is to conduct fundamental basic and translational research on cancer, through a highly innovative, multi-disciplinary and collaborative environment. We are committed to teaching and training the next generation of cancer researchers, within a diverse and inclusive research community. Through scientific innovation, we strive for global impact on the treatment, early diagnosis and prevention of all forms of cancer.
View a welcome message from Daniel Haber, MD, PhD, Director, Center for Cancer Research.
The Center for Cancer Research has a dedicated faculty of over 40 independent investigators using state-of-the-art tools in a variety of fields.
News & Events
View research highlights, news and featured publications from the Center for Cancer Research.
The mutation-independent immunogenic effect of environmental carcinogens blocks cancer metastasis
In a June 2021 Science Advances paper, Li et al. describe a distinct consequence of exposure to carcinogen that can have significant immunologic implications: the nongenetic induction of a chemokine called CCL21 in breast cancer cells that developed following an exposure to a chemical carcinogen.
Lee Zou, PhD and Raul Mostoslavsky, MD, PhD Named Scientific co-Directors
Congratulations to Lee Zou, PhD and Raul Mostoslavsky, MD, PhD who will serve as Scientific co-Directors of the Mass General Cancer Center and Center for Cancer Research.
Ultrahigh-throughput magnetic sorting of large blood volumes for epitope-agnostic isolation of circulating tumor cells
A team at Mass General has devised a new ultrahigh-throughput microfluidic chip (the LPCTC-iCHIP) that improves sensitivity of CTC-based assays 100-fold as compared to existing approaches. The team’s paper appeared recently in the May 2020 issue of Proceedings of the National Academy of Sciences.
Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma
Cancer researchers have identified changes in lung cancer-promoting genes that may allow the disease to metastasize to the brain. Their work, which points to possible therapies for preventing or treating brain metastases from lung cancer, is described in the March 2020 issue of Nature Genetics.
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
In a Feb 2020 paper published in Nature, CCR faculty members Gad Getz and Esther Rheinbay, together with their colleagues, studied the landscape of protein-coding and non-coding regulatory driver events in cancer.
ATR Protects the Genome against R Loops through a MUS81-Triggered Feedback Loop
In a February 2020 paper published in Molecular Cell, Matos and colleagues in the Zou laboratory reported that the ATR kinase is a key sensor of R loops and a suppressor of R loop-associated DNA damage.
Leading-edge Science Coupled with Innovative Care
Our vision is to contribute toward the eradication of cancer and lessen its burden across all communities, through scientific innovation and the rapid application of new discoveries.
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#1 Research Hospital in America
Mass General is the #1 Research Hospital in America and the only hospital to be recognized in all 16 specialties assessed by U.S. News & World Report.
Education & Training at the Cancer Center
A world leader in cancer research & comprehensive cancer treatment, we are dedicated to educating the next generation of cancer specialists.
Data Analyst Position
Unique opportunity to join an interdisciplinary team bridging the Harvard Medical School, the Massachusetts General Hospital, and the Broad Institute of Harvard and MIT. The Rheinbay Lab and Lawrence Lab at the Mass General Cancer Center seek well-qualified candidates to join a team of computational biologists working at the forefront of cancer research and treatment. We use computation as a powerful microscope to study both the fundamental biology of cancer initiation and progression, as well the diagnosis and treatment of cancer patients in the hospital setting. Learn more on the Rheinbay Lab and Lawrence Lab pages.
Postdoc Fellow Positions
- Postdoctoral Research Position in the Ting Lab
- Postdoctoral Research Position in the Rheinbay Lab
- Postdoctoral Research Position in the Haas Lab
- Postdoctoral Research Fellowships in Cancer Immunology
- Postdoctoral Research Position in the Iliopoulos Lab