Research labs at the Center for Immunology and Inflammatory Diseases at Massachusetts General Hospital.
Principal Investigators
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Robert Anthony, PhDThe Anthony Laboratory investigates the role and regulation of immunoglobulin glycosylation. |
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Donald Bloch, MDThe Bloch Laboratory investigates the role of the bone morphogenetic protein signal transduction pathway in a broad spectrum of human diseases. |
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Shannon Bromley, PhDThe Bromley Laboratory investigates lymphocyte migration, with an emphasis on the mechanisms that regulate the accumulation of T cells within normal and inflamed non-lymphoid tissues. |
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Joseph El Khoury, MDThe El Khoury Laboratory investigates the role of the innate immune system in neurodegeneration, inflammation and host defense against infectious pathogens. |
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Sabina Islam, MDThe Islam Laboratory investigates mechanisms regulating skin immunity and inflammation, and chemokine and associated pathways in chronic skin inflammation and host immunity. |
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David Lagares, PhDThe Lagares Laboratory investigates the fundamental mechanisms that balance tissue regeneration and fibrosis following injury. |
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Bo Li, PhDThe Li Laboratory focuses on developing standard operating procedures for single-cell genomics data analysis, building on state-of-the-art big data, machine learning and graphics processing unit computing technologies, and application of single-cell genomics to immunology questions. |
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Andrew D. Luster, MD, PhDThe Luster Laboratory investigates chemokines, lipid chemoattractants and their receptors in normal physiology and disease. |
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Benjamin Medoff, MDThe Medoff Laboratory studies the pathogenesis of pulmonary inflammation in a number of important lung diseases such as asthma, COPD, lung transplant rejection and viral infections. |
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Thorsten R. Mempel, MD, PhDThe Mempel Laboratory investigates cell migration and intercellular communication in the adaptive immune system through direct dynamic in vivo visualization of immune cell behavior using multiphoton intravital microscopy in mice. |
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James Moon, PhDThe Moon Laboratory focuses on basic issues of CD4+ T cell tolerance studied by directly tracking antigen-specific populations in mouse and human models. |
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Sarita Patil, MDThe Patil Laboratory is focused on the study of allergen-specific antibodies in allergic diseases. |
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Wayne Shreffler, MD, PhDThe Shreffler Laboratory is interested in the mechanisms regulating both primary sensitization and the subsequent balance between immune progression or regulation that determines either clinical sensitivity or tolerance to mucosal allergens. |
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Caroline Sokol, MD, PhDThe Sokol Laboratory investigates the innate and adaptive immune interactions that initiate the allergic immune response. |
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Allen Steere, MDThe Steere Laboratory does translational studies using samples from patients with Lyme arthritis or rheumatoid arthritis to delineate mechanisms involved in the pathogenesis of these diseases, to identify biomarkers of disease activity and to develop diagnostic tests. |
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Alexandra-Chloe Villani, PhDThe Villani Lab is developing and implementing single-cell 'omics' strategies and systems immunology approaches to human immune response regulation as a foundation for deciphering human traits and diseases. |
Associate Members
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Nir Hacohen, PhDThe Hacohen Laboratory develops new and unbiased strategies to understand basic immune processes and immune-mediated diseases. |
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Shiv Pillai, MD, PhDThe Pillai Laboratory investigates the biology of the immune system and human genetics. |
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