Lower Hydroxychloroquine Dosing is Less Effective in Preventing Lupus Flares

When patients with lupus received lower dosing of hydroxychloroquine—in accordance with current ophthalmology guidelines—they had a higher risk of lupus flares than when they were taking a higher dose of the medication.

Racial and Sex Disparities in the Prevalence of Gout Among US Adults

In this nationally representative race- and sex-specific cross-sectional study of US adults, gout was more prevalent in adults self-reporting Black race during a recent 10-year period compared with their White counterparts.

Understanding Infant Mortality Rate and Risk Factors in Nigeria

An increasing rate of infant mortality in Nigeria indicates that Nigeria is not on track to achieving the Sustainable Development Goal (SDG) target of reducing child mortality by 2030.

Could a Blood Pressure Hormone Work as a Treatment for Immune Dysregulation in Sepsis?

Angiotensin-II substantially increased bacterial clearance and enhanced immune function without worsening organ injury in a mouse model of sepsis, whereas norepinephrine, the current first line treatment for septic shock, did not.

Learning More About Treatment Resistance in A Highly Fatal Form of Pancreatic Cancer

A high-resolution molecular framework sheds light on the inter- and intratumoral diversity of pancreatic cancer, spatial organization into discrete communities, treatment-associated remodeling and clinically relevant prognostication.