The Praxis-MGH Neuroscience Clinical Research Scholars Program provides an opportunity for talented clinical or translational researchers to actively participate in a drug development program at Praxis Precision Medicines (Boston, MA). The Praxis pipeline stems from insights into the genetics of epilepsy and the application of those insights to broader neurological and psychiatric diseases. Current clinical stage programs focus on pediatric epilepsies, mood and anxiety disorders, movement disorders, headache, and pain. Scholars who are selected for this program will engage in all aspects of therapeutics development including translational medicine and biomarker development, toxicology and pharmacovigilance, clinical pharmacology, clinical trial design and execution, and regulatory affairs and will have the opportunity to focus on specific independent projects. This training will prepare candidates for leadership roles in clinical research in academic medicine or industry. 

Scholars will be selected by a joint Praxis-MGH committee. Candidates should have an MD or PhD, with clinical or translational research experience in a therapeutic area related to areas of interest listed above, and should be eligible for appointments within the department of Psychiatry or Neurology at Mass General Brigham. The selected Scholars will divide their time approximately equally over two years between their academic and clinical commitments at MGB and their drug development work at Praxis. Scholars will receive salary support and benefits from Praxis in accordance with their percent effort.

Interested applicants should send their CV and a brief (approximately 1 page) cover letter describing their interest in the program to Erica Ratti, Program Coordinator (eratti1@bwh.harvard.edu). Interviews will be scheduled accordingly, and the entire application process is expected to take approximately 45 days. Applications will be accepted on a rolling basis and up to two positions will be filled.

Questions or requests for additional information may be directed to Dr. Andrew Cole, Praxis Scholar Program Director (cole.andrew@mgh.harvard.edu).