Publication word cloud

In 2021, the Mass General Neurology faculty published more than 1,500 papers in journals like Neurology, Stroke, Nature, the New England Journal of Medicine and JAMA Neurology, and we are on track to surpass that record for 2022. Our research efforts advance our mission to rapidly discover new treatments to reduce and eliminate the devastating impact of neurological disorders. A selection of publications is below:

Racial and Ethnic Disparities Associated with Traumatic Brain Injury Across the Continuum of Care: a Narrative Review and Directions for Future Research.
Saadi A, Bannon S, Watson E, Vranceanu AM. J Racial Ethn Health Disparities. 2022 Jun;9(3):786-799. doi: 10.1007/s40615-021-01017-4.


Drivers of US Healthcare Spending for Persons with Seizures and/or Epilepsies, 2010-2018.
Moura LMVR, Karakis I, Zack MM, Tian N, Kobau R, Howard D. Epilepsia. 2022 May 17. doi: 10.1111/epi.17305.


Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial.
Paganoni S, Hendrix S, Dickson SP, Knowlton N, Berry JD, Elliott MA, Maiser S, Karam C, Caress JB, Owegi MA, Quick A, Wymer J, Goutman SA, Heitzman D, Heiman-Patterson TD, Jackson C, Quinn C, Rothstein JD, Kasarskis EJ, Katz J, Jenkins L, Ladha SS, Miller TM, Scelsa SN, Vu TH, Fournier C, Johnson KM, Swenson A, Goyal N, Pattee GL, Babu S, Chase M, Dagostino D, Hall M, Kittle G, Eydinov M, Ostrow J, Pothier L, Randall R, Shefner JM, Sherman AV, Tustison E, Vigneswaran P, Yu H, Cohen J, Klee J, Tanzi R, Gilbert W, Yeramian P, Cudkowicz M. J Neurol Neurosurg Psychiatry. 2022 May 16:jnnp-2022-329024. doi: 10.1136/jnnp-2022-329024.


Teleneurology and Health Disparities.
Saadi A, Mendizabal A, Mejia NI. Semin Neurol. 2022 Feb;42(1):60-66. doi: 10.1055/s-0041-1742194. Epub 2022 May 16.


Use of Artificial Intelligence in Clinical Neurology.
Hillis JM, Bizzo BC. Semin Neurol. 2022 Feb;42(1):39-47. doi: 10.1055/s-0041-1742180. Epub 2022 May 16.


Utilization of Telestroke Prior to and Following the COVID-19 Pandemic.
Turner AC, Etherton MR. Semin Neurol. 2022 Feb;42(1):3-11. doi: 10.1055/s-0041-1742181. Epub 2022 May 16.


Disease modifying therapy management of multiple sclerosis after stem cell therapies: A retrospective case series.
Manzano GS, Holroyd KB, Kaplan T, Bhattacharyya S, Chitnis T, Hotan G, Zurawski J, Galetta KM, Mateen FJ. Mult Scler Relat Disord. 2022 May 10;63:103861. doi: 10.1016/j.msard.2022.103861.


Comparison of common outcome measures for assessing independence in patients diagnosed with disorders of consciousness: A Traumatic Brain Injury Model Systems Study.
Snider SB, Kowalski RG, Hammond FM, Izzy S, Shih SL, Rovito C, Edlow BL, Zafonte RD, Giacino J, Bodien YG. J Neurotrauma. 2022 May 9. doi: 10.1089/neu.2022.0076


Survival Analyses From the CENTAUR Trial in Amyotrophic Lateral Sclerosis: Evaluating the Impact of Treatment Crossover on Outcomes.
Paganoni S, Watkins C, Cawson M, Hendrix S, Dickson SP, Knowlton N, Timmons J, Manuel M, Cudkowicz M. Muscle Nerve. 2022 May 4. doi: 10.1002/mus.27569. Online ahead of print. PMID: 35508892


A cultural approach to dementia - insights from US Latino and other minoritized groups.
Vila-Castelar C, Fox-Fuller JT, Guzmán-Vélez E, Schoemaker D, Quiroz YT. Nat Rev Neurol. 2022 May;18(5):307-314. doi: 10.1038/s41582-022-00630-z.


Understanding Delays in MRI-based Selection of Large Vessel Occlusion Stroke Patients for Endovascular Thrombectomy.
Regenhardt RW, Nolan NM, Rosenthal JA, McIntyre JA, Bretzner M, Bonkhoff AK, Snider SB, Das AS, Alotaibi NM, Vranic JE, Dmytriw AA, Stapleton CJ, Patel AB, Rost NS, Leslie-Mazwi TM. Clin Neuroradiol. 2022 Apr 29. doi: 10.1007/s00062-022-01165-y.


Regulatory Approval in ALS; When Is a Single Study Enough?
Cudkowicz ME, Shefner JM. Ann Neurol. 2022 Apr 28. doi: 10.1002/ana.26371. Online ahead of print. PMID: 35478359 No abstract available.


Targeting IDH-Mutant Glioma.
Miller JJ. Neurotherapeutics. 2022 Apr 27. doi: 10.1007/s13311-022-01238-3.


Anti-SARS-CoV-2 monoclonal antibodies for the treatment of active COVID-19 in multiple sclerosis: An observational study.
Manzano GS, Rice DR, Klawiter EC, Matiello M, Gillani RL, Tauhid SS, Bakshi R, Mateen FJ. Mult Scler. 2022 Apr 27:13524585221092309. doi: 10.1177/13524585221092309.


Chronic Circadian Disruption and Sleep Restriction Influence Subjective Hunger, Appetite, and Food Preference.
McHill AW, Hull JT, Klerman EB. Nutrients. 2022 Apr 26;14(9):1800. doi: 10.3390/nu14091800. PMID: 35565768


Longitudinal EEG model detects antisense oligonucleotide treatment effect and increased UBE3A in Angelman syndrome
Spencer ER, Shi W, Komorowski RW, Gilbert JP, Ostrowski LM, Byrd LM, Thibert R, Bao C, Molloy F, Calhoun M, Koirala S, Jafar-nejad P, Rigo F, Kramer MA, Chu CJ. Brain Communications. 2022 Apr 26. doi: /10.1093/braincomms/fcac106


Increased levels of the synaptic proteins PSD-95, SNAP-25, and neurogranin in the cerebrospinal fluid of patients with Alzheimer's disease.
Kivisäkk P, Carlyle BC, Sweeney T, Quinn JP, Ramirez CE, Trombetta BA, Mendes M, Brock M, Rubel C, Czerkowicz J, Graham D, Arnold SE. Alzheimers Res Ther. 2022 Apr 23;14(1):58. doi: 10.1186/s13195-022-01002-x.


High efficacy treatment is not enough in MS: Socioeconomic factors are key to improving outcomes.
Yeh EA, Giovannoni G, Hawkes C, Lechner-Scott J, Levy M. Mult Scler Relat Disord. 2022 Apr 22;61:103816. doi: 10.1016/j.msard.2022.103816.


Evaluation of Claims-Based Ascertainment of Alzheimer Disease and Related Dementias Across Health Care Settings
Festa N, Price M, Moura LMVR; Blacker D Normand S, Newhouse JP, Hsu J. JAMA Health Forum. 2022 Apr 22;3(4):e220653. doi:10.1001/jamahealthforum.2022.0653


Electrophysiological correlates of thalamocortical function in acute severe traumatic brain injury.
Curley WH, Bodien YG, Zhou DW, Conte MM, Foulkes AS, Giacino JT, Victor JD, Schiff ND, Edlow BL. Cortex. 2022 Apr 15;152:136-152. doi: 10.1016/j.cortex.2022.04.007.


Unmasked Facies.
Ferenczi EA. JAMA. 2022 Apr 14. doi: 10.1001/jama.2022.6307.


Development and Impact of a Progressive Parental Leave Policy in a Neurology Residency.
Conway SE, Vaswani PA, Budhu JA, Kett LR, Eaton SH, Wang W, Bowley MP, Prasad S. Neurology. 2022 Apr 13:10.1212/WNL.0000000000200729.


Amyloid-β and tau pathologies relate to distinctive brain dysconnectomics in preclinical autosomal-dominant Alzheimer's disease.
Guzmán-Vélez E, Diez I, Schoemaker D, Pardilla-Delgado E, Vila-Castelar C, Fox-Fuller JT, Baena A, Sperling RA, Johnson KA, Lopera F, Sepulcre J, Quiroz YT. Proc Natl Acad Sci U S A. 2022 Apr 12;119(15):e2113641119. doi: 10.1073/pnas.2113641119.


Tissue-specific and repeat length-dependent somatic instability of the X-linked dystonia parkinsonism-associated CCCTCT repeat.
Campion LN, Meijia Maza A, Yadav R, Penney EB, Murcar MG, Correia K, Gillis T, Fernandez-Cerado C, Velasco-Andrada MS, Legarda GP, Ganza-Bautista NG, Lagarde JBB, Acuña PJ, Multhaupt-Buell T, Aldykiewicz G, Supnet ML, De Guzman JK, Go C, Sharma N, Munoz EL, Ang MC, Diesta CCE, Bragg DC, Ozelius LJ, Wheeler VC. Acta Neuropathol Commun. 2022 Apr 8;10(1):49. doi: 10.1186/s40478-022-01349-0.


Should consistent command-following be added to the criteria for emergence from the minimally conscious state?
Golden K, Erler KS, Wong J, Giacino JT, Bodien YG. Arch Phys Med Rehabil. 2022 Apr 6:S0003-9993(22)00294-5. doi: 10.1016/j.apmr.2022.03.010.


Optimal deep brain stimulation sites and networks for cervical vs. generalized dystonia.
Horn A, Reich MM, Ewert S, Li N, Al-Fatly B, Lange F, Roothans J, Oxenford S, Horn I, Paschen S, Runge J, Wodarg F, Witt K, Nickl RC, Wittstock M, Schneider GH, Mahlknecht P, Poewe W, Eisner W, Helmers AK, Matthies C, Krauss JK, Deuschl G, Volkmann J, Kühn AA. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2114985119. doi: 10.1073/pnas.2114985119.


Case Report of Spinal Cord Involvement in Susac Syndrome Masquerading as a Multiple Sclerosis Mimic
Song KW, Manzano GS, Kharal GA, Venna N.The Neurohospitalist. April 2022.


Return to Work Within Four Months of Grade 3 Diffuse Axonal Injury.
Young MJ, Sanders WR, Marujo R, Bodien YG, Edlow BL. Neurohospitalist. 2022 Apr;12(2):280-284. doi: 10.1177/19418744211051459


Quantifying seizure termination patterns reveals limited pathways to seizure end.
Salami P, Borzello M, Kramer MA, Westover MB, Cash SS. Neurobiol Dis. 2022 Apr;165:105645. doi: 10.1016/j.nbd.2022.105645.


Plasma IL-12/IFN-γ axis predicts cognitive trajectories in cognitively unimpaired older adults.
Yang HS, Zhang C, Carlyle BC, Zhen SY, Trombetta BA, Schultz AP, Pruzin JJ, Fitzpatrick CD, Yau WW, Kirn DR, Rentz DM, Arnold SE, Johnson KA, Sperling RA, Chhatwal JP, Tanzi RE. Alzheimers Dement. 2022 Apr;18(4):645-653. doi: 10.1002/alz.12399.


Return to Work Within Four Months of Grade 3 Diffuse Axonal Injury.
Young MJ, Sanders WR, Marujo R, Bodien YG, Edlow BL. Neurohospitalist. 2022 Apr;12(2):280-284. doi: 10.1177/19418744211051459


Neuroprognostication: a conceptual framework.
Fischer D, Edlow BL, Giacino JT, Greer DM. Nat Rev Neurol. 2022 Mar 29. doi: 10.1038/s41582-022-00644-7.


Subthalamic and pallidal deep brain stimulation: are we modulating the same network?
Sobesky L, Goede L, Odekerken VJJ, Wang Q, Li N, Neudorfer C, Rajamani N, Al-Fatly B, Reich M, Volkmann J, de Bie RMA, Kühn AA, Horn A. Brain. 2022 Mar 29;145(1):251-262. doi: 10.1093/brain/awab258.


Evaluating the Impacts of Patient Engagement on Health Services Research Teams: Lessons from the Veteran Consulting Network.
Merker VL, Hyde JK, Herbst A, Solch AK, Mohr DC, Gaj L, Dvorin K, Dryden EM. J Gen Intern Med. 2022 Mar 29. doi: 10.1007/s11606-021-06987-z.


Consider Myocarditis When Patients Treated with Immune Checkpoint Inhibitors Present with Ocular Symptoms
Rhee JY, Torun N, Neilan TG, Guidon AC. The Oncologist. 2022 Mar 28. doi: 10.1093/oncolo/oyac033


Cost-effectiveness of Aducanumab and Donanemab for Early Alzheimer Disease in the US.
Ross EL, Weinberg MS, Arnold SE. JAMA Neurol. 2022 Mar 28. doi: 10.1001/jamaneurol.2022.0315.


Transverse endoplasmic reticulum expansion in hereditary spastic paraplegia corticospinal axons.
Zhu PP, Hung HF, Batchenkova N, Nixon-Abell J, Henderson J, Zheng P, Renvoisé B, Pang S, Xu CS, Saalfeld S, Funke J, Xie Y, Svara F, Hess HF, Blackstone C. Hum Mol Genet. 2022 Mar 26:ddac072. doi: 10.1093/hmg/ddac072.


Neuro-Ophthalmological Complications of the COVID-19 Vaccines: A Systematic Review.
Lotan I, Lydston M, Levy M. J Neuroophthalmol. 2022 Mar 25. doi: 10.1097/WNO.0000000000001537.


Association of Emerging β-Amyloid and Tau Pathology With Early Cognitive Changes in Clinically Normal Older Adults. Papp KV, Buckley RF, Jacobs HIL, Schultz AP, Properzi MJ, Vannini P, Hanseeuw BJ, Rentz DM, Johnson KA, Sperling RA. Neurology. 2022 Mar 25:10.1212/WNL.0000000000200137. doi: 10.1212/WNL.0000000000200137.


In a hub-and-spoke network, spoke-administered thrombolysis reduces mechanical thrombectomy procedure time and number of passes.
Kraft AW, Awad A, Rosenthal JA, Dmytriw AA, Vranic JE, Bonkhoff AK, Bretzner M, Hirsch JA, Rabinov JD, Stapleton CJ, Schwamm LH, Rost NS, Leslie-Mazwi TM, Patel AB, Regenhardt RW. Interv Neuroradiol. 2022 Mar 23:15910199221087498. doi: 10.1177/15910199221087498.


Regional variability and genotypic and pharmacodynamic effects on PrP concentration in the CNS.
Mortberg MA, Zhao HT, Reidenbach AG, Gentile JE, Kuhn E, O'Moore J, Dooley PM, Connors TR, Mazur C, Allen SW, Trombetta BA, McManus A, Moore MR, Liu J, Cabin DE, Kordasiewicz HB, Mathews J, Arnold SE, Vallabh SM, Minikel EV. JCI Insight. 2022 Mar 22;7(6):e156532. doi: 10.1172/jci.insight.156532


Autoimmune and Paraneoplastic Chorea: A Review of the Literature.
Kyle K, Bordelon Y, Venna N, Linnoila J. Front Neurol. 2022 Mar 18;13:829076. doi: 10.3389/fneur.2022.829076.


Genetic modifiers of Huntington disease differentially influence motor and cognitive domains.
Lee JM, Huang Y, Orth M, Gillis T, Siciliano J, Hong E, Mysore JS, Lucente D, Wheeler VC, Seong IS, McLean ZL, Mills JA, McAllister B, Lobanov SV, Massey TH, Ciosi M, Landwehrmeyer GB, Paulsen JS, Dorsey ER, Shoulson I, Sampaio C, Monckton DG, Kwak S, Holmans P, Jones L, MacDonald ME, Long JD, Gusella JF. Am J Hum Genet. 2022 Mar 18:S0002-9297(22)00100-8. doi: 10.1016/j.ajhg.2022.03.004.


Implications of Low-Titer MOG Antibodies.
Levy M, Yeh EA, Hawkes CH, Lechner-Scott J, Giovannoni G. Mult Scler Relat Disord. 2022 Mar 17;59:103746. doi: 10.1016/j.msard.2022.103746.


Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease.
Jacobs HIL, Becker JA, Kwong K, Munera D, Ramirez-Gomez L, Engels-Domínguez N, Sanchez JS, Vila-Castelar C, Baena A, Sperling RA, Johnson KA, Lopera F, Quiroz YT. Alzheimers Dement. 2022 Mar 17. doi: 10.1002/alz.12656.


Racial and socioeconomic status differences in stress, posttraumatic growth, and mental health in an older adult cohort during the COVID-19 pandemic.
Willey B, Mimmack K, Gagliardi G, Dossett ML, Wang S, Udeogu OJ, Donovan NJ, Gatchel JR, Quiroz YT, Amariglio R, Liu CH, Hyun S, ElTohamy A, Rentz D, Sperling RA, Marshall GA, Vannini P. EClinicalMedicine. 2022 Mar 13;45:101343. doi: 10.1016/j.eclinm.2022.101343.


Body imaging for newly diagnosed CNS lymphoma: Evaluating the utility of the evaluation.
Miller JJ, Wang N. Neuro Oncol. 2022 Mar 12;24(3):492-493. doi: 10.1093/neuonc/noab305.


Association of Modified Rankin Scale With Recovery Phenotypes in Patients With Upper Extremity Weakness After Stroke.
Erler KS, Wu R, DiCarlo JA, Petrilli MF, Gochyyev P, Hochberg LR, Kautz SA, Schwamm LH, Cramer SC, Finklestein SP, Lin DJ. Neurology. 2022 Mar 11:10.1212/WNL.0000000000200154. doi: 10.1212/WNL.0000000000200154.


Long-Term Blood Pressure Variability and Major Adverse Cardiovascular and Cerebrovascular Events After Intracerebral Hemorrhage.
Castello JP, Teo KC, Abramson JR, Keins S, Takahashi CE, Leung IYH, Leung WCY, Wang Y, Kourkoulis C, Pavlos Myserlis E, Warren AD, Henry J, Chan KH, Cheung RTF, Ho SL, Gurol ME, Viswanathan A, Greenberg SM, Anderson CD, Lau KK, Rosand J, Biffi A. J Am Heart Assoc. 2022 Mar 5:e024158. doi: 10.1161/JAHA.121.024158.


Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2.
Prokopenko D, Lee S, Hecker J, Mullin K, Morgan S, Katsumata Y; Alzheimer’s Disease Neuroimaging Initiative (ADNI), Weiner MW, Fardo DW, Laird N, Bertram L, Hide W, Lange C, Tanzi RE. Mol Psychiatry. 2022 Mar 4. doi: 10.1038/s41380-022-01475-0.


Discovery and Optimization of Tau Targeted Protein Degraders Enabled by Patient Induced Pluripotent Stem Cells-Derived Neuronal Models of Tauopathy.
Silva MC, Nandi G, Donovan KA, Cai Q, Berry BC, Nowak RP, Fischer ES, Gray NS, Ferguson FM, Haggarty SJ. Front Cell Neurosci. 2022 Mar 3;16:801179. doi: 10.3389/fncel.2022.801179.


Enhancing demethylation-induced differentiation in IDH-mutant glioma.
Miller JJ, Cahill DP, Arrillaga-Romany I. Neuro Oncol. 2022 Mar 3:noac056. doi: 10.1093/neuonc/noac056.


End the use of "excited delirium" as a cause of death in police custody.
Saadi A, Naples-Mitchell J, da Silva Bhatia B, Heisler M. Lancet. 2022 Mar 2:S0140-6736(22)00410-X. doi: 10.1016/S0140-6736(22)00410-X.


Local and distant cortical responses to single pulse intracranial stimulation in the human brain are differentially modulated by specific stimulation parameters.
Paulk AC, Zelmann R, Crocker B, Widge AS, Dougherty DD, Eskandar EN, Weisholtz DS, Richardson RM, Cosgrove GR, Williams ZM, Cash SS. Brain Stimul. 2022 Mar 2:S1935-861X(22)00045-6. doi: 10.1016/j.brs.2022.02.017.


Maximizing Brain Health After Hemorrhagic Stroke: Bugher Foundation Centers of Excellence.
Sheth KN, Anderson CD, Biffi A, Dlamini N, Falcone GJ, Fox CK, Fullerton HJ, Greenberg SM, Hemphill JC, Kim A, Kim H, Ko NU, Roland JL, Sansing LH, van Veluw SJ, Rosand J. Stroke. 2022 Mar;53(3):1020-1029. doi: 10.1161/STROKEAHA.121.036197.


Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer's Symposium.
Quiroz YT, Solis M, Aranda MP, Arbaje AI, Arroyo-Miranda M, Cabrera LY, Carrasquillo MM, Corrada MM, Crivelli L, Diminich ED, Dorsman KA, Gonzales M, González HM, Gonzalez-Seda AL, Grinberg LT, Guerrero LR, Hill CV, Jimenez-Velazquez IZ, Guerra JJL, Lopera F, Maestre G, Medina LD, O'Bryant S, Peñaloza C, Pinzon MM, Mavarez RVP, Pluim CF, Raman R, Rascovsky K, Rentz DM, Reyes Y, Rosselli M, Tansey MG, Vila-Castelar C, Zuelsdorff M, Carrillo M, Sexton C. Alzheimers Dement. 2022 Feb 24. doi: 10.1002/alz.12589.


Neuropsychiatric Treatment Approaches for Functional Neurological Disorder: A How to Guide.
Finkelstein SA, Adams C, Tuttle M, Saxena A, Perez DL. Semin Neurol. 2022 Feb 21. doi: 10.1055/s-0042-1742773.


Genetic Architecture of Stroke of Undetermined Source: Overlap with Known Stroke Etiologies and Associations with Modifiable Risk Factors.
Georgakis MK, Parodi L, Frerich S, Mayerhofer E, Tsivgoulis G, Pirruccello JP, Slowik A, Rundek T, Malik R, Dichgans M, Rosand J, Anderson CD; NINDS Stroke Genetics Network (SiGN). Ann Neurol. 2022 Feb 17. doi: 10.1002/ana.26332.


A Neural Circuit for Spirituality and Religiosity Derived From Patients With Brain Lesions.
Ferguson MA, Schaper FLWVJ, Cohen A, Siddiqi S, Merrill SM, Nielsen JA, Grafman J, Urgesi C, Fabbro F, Fox MD. Biol Psychiatry. 2022 Feb 15;91(4):380-388. doi: 10.1016/j.biopsych.2021.06.016.


Personalizing deep brain stimulation using advanced imaging sequences.
Neudorfer C, Kroneberg D, Al-Fatly B, Goede L, Kübler D, Faust K, van Rienen U, Tietze A, Picht T, Herrington TM, Middlebrooks EH, Kühn A, Schneider GH, Horn A. Ann Neurol. 2022 Feb 14. doi: 10.1002/ana.26326.


Awareness and agreement with neurofibromatosis care guidelines among U.S. neurofibromatosis specialists.
Merker VL, Knight P, Radtke HB, Yohay K, Ullrich NJ, Plotkin SR, Jordan JT. Orphanet J Rare Dis. 2022 Feb 10;17(1):44. doi: 10.1186/s13023-022-02196-x.


Reply to Neupane et al.: Replication study of AD-associated rare variants.
Prokopenko D, Morgan SL, Lange C, Hide W, Bertram L, Tanzi RE. Alzheimers Dement. 2022 Feb 9. doi: 10.1002/alz.12584.


PrP concentration in the central nervous system: regional variability, genotypic effects, and pharmacodynamic impact.
Mortberg MA, Zhao HT, Reidenbach AG, Gentile JE, Kuhn E, O'Moore J, Dooley PM, Connors TR, Mazur C, Allen SW, Trombetta BA, McManus AJ, Moore MR, Liu J, Cabin DE, Kordasiewicz HB, Mathews J, Arnold SE, Vallabh SM, Minikel EV. JCI Insight. 2022 Feb 8:e156532. doi: 10.1172/jci.insight.156532.


Alpha-delta sleep pattern in an acute functional neurological patient with no perception of sleep.
Christian F, Pollak A, Sullivan L. J Clin Sleep Med. 2022 Feb 7. doi: 10.5664/jcsm.9924.


Biological and Social Determinants of Hypertension Severity Before vs After Intracerebral Hemorrhage.
Abramson JR, Castello JP, Keins S, Kourkoulis C, Rodriguez-Torres A, Myserlis EP, Alabsi H, Warren AD, Henry JQA, Gurol ME, Viswanathan A, Greenberg SM, Towfighi A, Skolarus L, Anderson CD, Rosand J, Biffi A. Neurology. 2022 Feb 7:10.1212/WNL.0000000000200003. doi: 10.1212/WNL.0000000000200003.


Histopathological correlates of haemorrhagic lesions on ex vivo magnetic resonance imaging in immunized Alzheimer's disease cases.
Scherlek AA, Kozberg MG, Nicoll JAR, Perosa V, Freeze WM, van der Weerd L, Bacskai BJ, Greenberg SM, Frosch MP, Boche D, van Veluw SJ. Brain Commun. 2022 Feb 3;4(1):fcac021. doi: 10.1093/braincomms/fcac021.


Using the Biopsychosocial Model to Guide Patient-Centered Neurological Treatments.
Saxena A, Paredes-Echeverri S, Michaelis R, Popkirov S, Perez DL. Semin Neurol. 2022 Feb 3. doi: 10.1055/s-0041-1742145.


Adult-Onset Leukoencephalopathy With Axonal Spheroids and Pigmented Glia: Review of Clinical Manifestations as Foundations for Therapeutic Development.
Papapetropoulos S, Pontius A, Finger E, Karrenbauer V, Lynch DS, Brennan M, Zappia S, Koehler W, Schoels L, Hayer SN, Konno T, Ikeuchi T, Lund T, Orthmann-Murphy J, Eichler F, Wszolek ZK. Front Neurol. 2022 Feb 3;12:788168. doi: 10.3389/fneur.2021.788168.


Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer's disease.
Muñoz-Castro C, Noori A, Magdamo CG, Li Z, Marks JD, Frosch MP, Das S, Hyman BT, Serrano-Pozo A. J Neuroinflammation. 2022 Feb 2;19(1):30. doi: 10.1186/s12974-022-02383-4.


Sex-specific lesion pattern of functional outcomes after stroke.
Bonkhoff AK, Bretzner M, Hong S, Schirmer MD, Cohen A, Regenhardt RW, Donahue KL, Nardin MJ, Dalca AV, Giese AK, Etherton MR, Hancock BL, Mocking SJT, McIntosh EC, Attia J, Benavente OR, Bevan S, Cole JW, Donatti A, Griessenauer CJ, Heitsch L, Holmegaard L, Jood K, Jimenez-Conde J, Kittner SJ, Lemmens R, Levi CR, McDonough CW, Meschia JF, Phuah CL, Rolfs A, Ropele S, Rosand J, Roquer J, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Söderholm M, Sousa A, Stanne TM, Strbian D, Tatlisumak T, Thijs V, Vagal A, Wasselius J, Woo D, Zand R, McArdle PF, Worrall BB, Jern C, Lindgren AG, Maguire J, Fox MD, Bzdok D, Wu O, Rost NS; MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium. Brain Commun. 2022 Feb 2;4(2):fcac020. doi: 10.1093/braincomms/fcac020.


Ethical Considerations in Clinical Trials for Disorders of Consciousness.
Young MJ, Bodien YG, Edlow BL. Brain Sci. 2022 Feb 2;12(2):211. doi: 10.3390/brainsci12020211.


FastSurferVINN: Building Resolution-Independence into Deep Learning Segmentation Methods - A Solution for HighRes Brain MRI.
Henschel L, Kügler D, Reuter M. Neuroimage. 2022 Feb 2:118933. doi: 10.1016/j.neuroimage.2022.118933.


Sex differences in cognitive resilience in preclinical autosomal-dominant Alzheimer's disease carriers and non-carriers: Baseline findings from the API ADAD Colombia Trial.
Vila-Castelar C, Tariot PN, Sink KM, Clayton D, Langbaum JB, Thomas RG, Chen Y, Su Y, Chen K, Hu N, Giraldo-Chica M, Tobón C, Acosta-Baena N, Luna E, Londoño M, Ospina P, Tirado V, Muñoz C, Henao E, Bocanegra Y, Alvarez S, Rios-Romenets S, Ghisays V, Goradia D, Lee W, Luo J, Malek-Ahmadi MH, Protas HD, Lopera F, Reiman EM, Quiroz YT; API ADAD Colombia Trial Group. Alzheimers Dement. 2022 Feb 1. doi: 10.1002/alz.12552.


Variant-dependent heterogeneity in amyloid beta burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study. Chhatwal JP, Schultz SA, McDade E, Schultz AP, Liu L, Hanseeuw BJ, Joseph-Mathurin N, Feldman R, Fitzpatrick CD, Sparks KP, Levin J, Berman SB, Renton AE, Esposito BT, Fernandez MV, Sung YJ, Lee JH, Klunk WE, Hofmann A, Noble JM, Graff-Radford N, Mori H, Salloway SM, Masters CL, Martins R, Karch CM, Xiong C, Cruchaga C, Perrin RJ, Gordon BA, Benzinger TLS, Fox NC, Schofield PR, Fagan AM, Goate AM, Morris JC, Bateman RJ, Johnson KA, Sperling RA; Dominantly Inherited Alzheimer's Network Investigators. Lancet Neurol. 2022 Feb;21(2):140-152. doi: 10.1016/S1474-4422(21)00375-6.


Systematic review of human post-mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease.
Viejo L, Noori A, Merrill E, Das S, Hyman BT, Serrano-Pozo A. Neuropathol Appl Neurobiol. 2022 Feb;48(1):e12753. doi: 10.1111/nan.12753.


Large-scale neural recordings with single neuron resolution using Neuropixels probes in human cortex.
Paulk AC, Kfir Y, Khanna AR, Mustroph ML, Trautmann EM, Soper DJ, Stavisky SD, Welkenhuysen M, Dutta B, Shenoy KV, Hochberg LR, Richardson RM, Williams ZM, Cash SS. Nat Neurosci. 2022 Jan 31. doi: 10.1038/s41593-021-00997-0.


Association of Infarct Topography and Outcome After Endovascular Thrombectomy in Patients With Acute Ischemic Stroke.
Regenhardt RW, Bonkhoff AK, Bretzner M, Etherton MR, Das AS, Hong S, Alotaibi NM, Vranic JE, Dmytriw AA, Stapleton CJ, Patel AB, Leslie-Mazwi TM, Rost NS. Neurology. 2022 Jan 31:10.1212/WNL.0000000000200034. doi: 10.1212/WNL.0000000000200034.


Emerging Subspecialties in Neurology: Neuroethics: An Emerging Career Path in Neurology.
Young MJ, Bernat JL. Neurology. 2022 Jan 31:10.1212/WNL.0000000000200054. doi: 10.1212/WNL.0000000000200054.


Aura Type and Outcome Following Anterior Temporal Lobectomy.
Rendon LF, Bick SK, Cash SS, Cole AJ, Eskandar EN, Williams ZM. World Neurosurg. 2022 Jan 30:S1878-8750(22)00117-6. doi: 10.1016/j.wneu.2022.01.103.


Is EBV the cause of multiple sclerosis?
Giovannoni G, Hawkes CH, Lechner-Scott J, Levy M, Yeh EA, Gold J. Mult Scler Relat Disord. 2022 Jan 29;58:103636. doi: 10.1016/j.msard.2022.103636.


Effect of vascular amyloid on white matter disease is mediated by vascular dysfunction in cerebral amyloid angiopathy.
Gokcal E, Horn MJ, Becker JA, Das AS, Schwab K, Biffi A, Rost N, Rosand J, Viswanathan A, Polimeni JR, Johnson KA, Greenberg SM, Gurol ME. J Cereb Blood Flow Metab. 2022 Jan 28:271678X221076571. doi: 10.1177/0271678X221076571.


Imbalance and dizziness caused by unilateral vestibular schwannomas correlate with vestibulo-ocular reflex precision and bias.
King S, Dahlem K, Karmali F, Stankovic KM, Welling DB, Lewis RF. J Neurophysiol. 2022 Jan 26. doi: 10.1152/jn.00725.2020.


Diagnosis and management of functional neurological disorder.
Aybek S, Perez DL. BMJ. 2022 Jan 24;376:o64. doi: 10.1136/bmj.o64


Episodic Memory Impairment Mediates the Loss of Awareness in Mild Cognitive Impairment.
Gagliardi G, Vannini P. Front Aging Neurosci. 2022 Jan 21;13:802501. doi: 10.3389/fnagi.2021.802501.


Human brain mapping with multithousand-channel PtNRGrids resolves spatiotemporal dynamics.
Tchoe Y, Bourhis AM, Cleary DR, Stedelin B, Lee J, Tonsfeldt KJ, Brown EC, Siler DA, Paulk AC, Yang JC, Oh H, Ro YG, Lee K, Russman SM, Ganji M, Galton I, Ben-Haim S, Raslan AM, Dayeh SA. Sci Transl Med. 2022 Jan 19;14(628):eabj1441. doi: 10.1126/scitranslmed.abj1441.


Disorders of Consciousness Associated With COVID-19: A Prospective Multimodal Study of Recovery and Brain Connectivity.
Fischer D, Snider SB, Barra ME, Sanders WR, Rapalino O, Schaefer P, Foulkes AS, Bodien YG, Edlow BL. Neurology. 2022 Jan 18;98(3):e315-e325. doi: 10.1212/WNL.0000000000013067.


VE-CAM-S: Visual EEG-Based Grading of Delirium Severity and Associations With Clinical Outcomes.
Tesh RA, Sun H, Jing J, Westmeijer M, Neelagiri A, Rajan S, Krishnamurthy PV, Sikka P, Quadri SA, Leone MJ, Paixao L, Panneerselvam E, Eckhardt C, Struck AF, Kaplan PW, Akeju O, Jones D, Kimchi EY, Westover MB. Crit Care Explor. 2022 Jan 18;4(1):e0611. doi: 10.1097/CCE.0000000000000611.


Integration of Waiting Room "Know Your Rights" Education into Medical Care of Immigrant Patients in a Federally Qualified Health Center: A Case Study.
Franco-Vásquez A, Lemus S, Castillo K, Isaac M, Saadi A. Health Equity. 2022 Jan 17;6(1):13-20. doi: 10.1089/heq.2020.0145


A brain network for deep brain stimulation induced cognitive decline in Parkinson's disease.
Reich MM, Hsu J, Ferguson M, Schaper FLWVJ, Joutsa J, Roothans J, Nickl RC, Frankemolle-Gilbert A, Alberts J, Volkmann J, Fox MD. Brain. 2022 Jan 17:awac012. doi: 10.1093/brain/awac012.


Measuring expertise in identifying interictal epileptiform discharges.
Harid NM, Jing J, Hogan J, Nascimento FA, Ouyang A, Zheng WL, Ge W, Zafar SF, Kim JA, Lam AD, Herlopian A, Maus D, Karakis I, Ng M, Hong S, Zhu Y, Kaplan PW, Cash S, Shafi M, Martz G, Halford JJ, Westover MB. Epileptic Disord. 2022 Jan 14. doi: 10.1684/epd.2021.1409.


Monthly At-Home Computerized Cognitive Testing to Detect Diminished Practice Effects in Preclinical Alzheimer's Disease.
Jutten RJ, Rentz DM, Fu JF, Mayblyum DV, Amariglio RE, Buckley RF, Properzi MJ, Maruff P, Stark CE, Yassa MA, Johnson KA, Sperling RA, Papp KV. Front Aging Neurosci. 2022 Jan 13;13:800126. doi: 10.3389/fnagi.2021.800126.


A neural network for tics: insights from causal brain lesions and deep brain stimulation.
Ganos C, Al-Fatly B, Fischer JF, Baldermann JC, Hennen C, Visser-Vandewalle V, Neudorfer C, Martino D, Li J, Bouwens T, Ackermanns L, Leentjens AFG, Pyatigorskaya N, Worbe Y, Fox MD, Kühn AA, Horn A. Brain. 2022 Jan 13:awac009. doi: 10.1093/brain/awac009.


Neuronal subtype-specific growth cone and soma purification from mammalian CNS via fractionation and fluorescent sorting for subcellular analyses and spatial mapping of local transcriptomes and proteomes.
Engmann AK, Hatch JJ, Nanda P, Veeraraghavan P, Ozkan A, Poulopoulos A, Murphy AJ, Macklis JD. Nat Protoc. 2022 Jan 12. doi: 10.1038/s41596-021-00638-7.


Neuroethics in the Era of Teleneurology.
Young MJ. Semin Neurol. 2022 Jan 11. doi: 10.1055/s-0041-1741496.


Body imaging for newly diagnosed CNS lymphoma: evaluating the utility of the evaluation.
Miller JJ, Wang N. Neuro Oncol. 2022 Jan 10:noab305. doi: 10.1093/neuonc/noab305.


The use of bracing in the management of lumbar spondylolysis.
Ibiebele A, Scott D, D'Hemecourt P, Meehan WP 3rd. PM R. 2022 Jan 10. doi: 10.1002/pmrj.12756.


Neuropathology of Vascular Brain Health: Insights From Ex Vivo Magnetic Resonance Imaging-Histopathology Studies in Cerebral Small Vessel Disease.
van Veluw SJ, Arfanakis K, Schneider JA. Stroke. 2022 Jan 10:STROKEAHA121032608. doi: 10.1161/STROKEAHA.121.032608.


Natural language processing in psychiatry: the promises and perils of a transformative approach.
Rezaii N, Wolff P, Price BH. Br J Psychiatry. 2022 Jan 7:1-3. doi: 10.1192/bjp.2021.188.


Middle meningeal artery embolization: preventing subdural hematoma recurrence and saving money?
Regenhardt RW, Dmytriw AA, Vranic JE, Patel AB, Stapleton CJ. J Neurointerv Surg. 2022 Jan 5:neurintsurg-2021-018441. doi: 10.1136/neurintsurg-2021-018441


Optimal Spindle Detection Parameters for Predicting Cognitive Performance.
Adra N, Sun H, Ganglberger W, Ye EM, Dümmer LW, Tesh RA, Westmeijer M, Cardoso MDS, Kitchener E, Ouyang A, Salinas J, Rosand J, Cash SS, Thomas RJ, Westover MB. Sleep. 2022 Jan 4:zsac001. doi: 10.1093/sleep/zsac001.


Examining the Association Between Childhood Trauma, Brain Injury, and Neurobehavioral Symptoms Among Survivors of Intimate Partner Violence: A Cross-Sectional Analysis.
Saadi A, Chibnik L, Valera E. J Head Trauma Rehabil. 2022 Jan-Feb 01;37(1):24-33. doi: 10.1097/HTR.0000000000000752.


Quantifying the relationship between disability progression and quality of life in patients treated for NMOSD: Insights from the SAkura studies.
Levy M, Haycox AR, Becker U, Costantino C, Damonte E, Klingelschmitt G, von Büdingen HC, Wallenstein G, Maio DD, Szczechowski L. Mult Scler Relat Disord. 2022 Jan;57:103332. doi: 10.1016/j.msard.2021.103332.


Differentiation of Human Induced Pluripotent Stem Cells into Cortical Neurons to Advance Precision Medicine.
Silva MC, Nandi G, Haggarty SJ. Methods Mol Biol. 2022;2429:143-174. doi: 10.1007/978-1-0716-1979-7_10.


Sensitivity of the Preclinical Alzheimer's Cognitive Composite (PACC), PACC5, and Repeatable Battery for Neuropsychological Status (RBANS) to Amyloid Status in Preclinical Alzheimer's Disease -Atabecestat Phase 2b/3 EARLY Clinical Trial.
Papp KV, Rofael H, Veroff AE, Donohue MC, Wang S, Randolph C, Grober E, Brashear HR, Novak G, Ernstrom K, Raman R, Aisen PS, Sperling R, Romano G, Henley D. J Prev Alzheimers Dis. 2022;9(2):255-261. doi: 10.14283/jpad.2022.17.


Functional MRI evidence for reorganization of language networks after stroke.
Li R, Mukadam N, Kiran S. Handb Clin Neurol. 2022;185:131-150. doi: 10.1016/B978-0-12-823384-9.00007-4.


The Mind After Midnight: Nocturnal Wakefulness, Behavioral Dysregulation, and Psychopathology.
Tubbs AS, Fernandez FX, Grandner MA, Perlis ML, Klerman EB. Front Netw Physiol. 2022;1:830338. doi: 10.3389/fnetp.2021.830338.

Earlier Publications