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In 2020, the Mass General Neurology faculty published more than 1,000 papers in journals like Neurology, Stroke, and JAMA Neurology, and we are on track to surpass that record for 2021. Our research efforts advance our mission to rapidly discover new treatments to reduce and eliminate the devastating impact of neurological disorders.

Re-CHARGE-AF: Recalibration of the CHARGE-AF Model for Atrial Fibrillation Risk Prediction in Patients With Acute Stroke.
Ashburner JM, Wang X, Li X, Khurshid S, Ko D, Trisini Lipsanopoulos A, Lee PR, Carmichael T, Turner AC, Jackson C, Ellinor PT, Benjamin EJ, Atlas SJ, Singer DE, Trinquart L, Lubitz SA, Anderson CD. J Am Heart Assoc. 2021 Oct 20:e022363. doi: 10.1161/JAHA.121.022363.


ALSUntangled #63: ketogenic diets.
Bedlack R, Barkhaus PE, Barnes B, Beauchamp M, Bertorini T, Bromberg MB, Carter GT, Chaudry V, Cudkowicz M, Jackson C, Levitsky G, Lund I, McDermott C, Novella S, Olby N, Ostrow L, Pattee GL, Heiman-Patterson T, Ratner D, Salmon K, Steves S, Terrelonge M, Wicks P, Wills AM. Amyotroph Lateral Scler Frontotemporal Degener. 2021 Oct 14:1-5. doi: 10.1080/21678421.2021.1990346.


Frequency and Prognostic Significance of Clinical Fluctuations Before Hospital Arrival in Stroke.
Romano JG, Gardener H, Smith EE, Campo-Bustillo I, Khan Y, Tai S, Riley N, Sacco RL, Khatri P, Alger HM, Mac Grory B, Gulati D, Sangha NS, Olds KE, Benesch CG, Kelly AG, Brehaut SS, Kansara AC, Schwamm LH; MaRISS Investigators. Stroke. 2021 Oct 14:STROKEAHA121034124. doi: 10.1161/STROKEAHA.121.034124.


Long-Term Recovery from Disordered Consciousness Associated with COVID-19.
Fischer D, Edlow BL. Neurocrit Care. 2021 Oct 12:1-3. doi: 10.1007/s12028-021-01367-1.


Sociodemographic and clinical factors associated with depression, anxiety, and general mental health in people with multiple sclerosis during the COVID-19 pandemic. Uhr L, Rice DR, Mateen FJ. Mult Scler Relat Disord. 2021 Oct 11;56:103327. doi: 10.1016/j.msard.2021.103327.


On the dynamic and even reversible nature of Leigh syndrome: Lessons from human imaging and mouse models.
Walker MA, Miranda M, Allred A, Mootha VK. Curr Opin Neurobiol. 2021 Oct 13;72:80-90. doi: 10.1016/j.conb.2021.09.006.


Altered adipokine levels are associated with dimethyl fumarate treatment in multiple sclerosis patients.
Baharnoori M, Wilson R, Saxena S, Gonzalez CT, Sotiropoulos MG, Keyhanian K, Healy BC, Chitnis T. Mult Scler Relat Disord. 2021 Oct 4;56:103311. doi: 10.1016/j.msard.2021.103311.


Early Rehabilitation for Patients with Disorders of Consciousness after Severe COVID-19.
Edlow BL. Neurocrit Care. 2021 Oct 6:1-3. doi: 10.1007/s12028-021-01361-7.


Diagnosing Level of Consciousness: The Limits of the Glasgow Coma Scale Total Score.
Bodien Y, Barra A, Temkin N, Barber J, Foreman B, Vassar M, Robertson CS, Taylor SR, Markowitz AJ, Manley GT, Giacino J, Edlow BL. J Neurotrauma. 2021 Oct 4. doi: 10.1089/neu.2021.0199.


Central Nervous System Complications Among Oncology Patients.
Winter SF, Jo J, Schiff D, Dietrich J. Hematol Oncol Clin North Am. 2021 Oct 2:S0889-8588(21)00108-8. doi: 10.1016/j.hoc.2021.08.005.


Seizures, Status Epilepticus, and Continuous EEG in the Intensive Care Unit.
Rosenthal ES. Continuum (Minneap Minn). 2021 Oct 1;27(5):1321-1343. doi: 10.1212/CON.0000000000001012.


Posterior Reversible Encephalopathy Syndrome and Reversible Cerebral Vasoconstriction Syndrome as Syndromes of Cerebrovascular Dysregulation.
Singhal AB. Continuum (Minneap Minn). 2021 Oct 1;27(5):1301-1320. doi: 10.1212/CON.0000000000001037.


Editorial: Vestibular Contributions to Health and Disease, Volume II-Dedicated to Bernard Cohen.
Lewis RF, Strupp M. Front Neurol. 2021 Oct 1;12:760822. doi: 10.3389/fneur.2021.760822. eCollection 2021.


Safety and efficacy of oral levosimendan in people with amyotrophic lateral sclerosis (the REFALS study): a randomised, double-blind, placebo-controlled phase 3 trial.
Cudkowicz M, Genge A, Maragakis N, Petri S, van den Berg L, Aho VV, Sarapohja T, Kuoppamäki M, Garratt C, Al-Chalabi A; REFALS investigators. Lancet Neurol. 2021 Oct;20(10):821-831. doi: 10.1016/S1474-4422(21)00242-8.


Evaluation and Management of Delirium.
Ryan SL, Kimchi EY. Semin Neurol. 2021 Oct;41(5):572-587. doi: 10.1055/s-0041-1733791. Epub 2021 Oct 7.


Unsupervised mobile cognitive testing for use in preclinical Alzheimer's disease.
Papp KV, Samaroo A, Chou HC, Buckley R, Schneider OR, Hsieh S, Soberanes D, Quiroz Y, Properzi M, Schultz A, García-Magariño I, Marshall GA, Burke JG, Kumar R, Snyder N, Johnson K, Rentz DM, Sperling RA, Amariglio RE. Alzheimers Dement (Amst). 2021 Sep 30;13(1):e12243. doi: 10.1002/dad2.12243.


Cerebral Small Vessel Disease and Depression Among Intracerebral Hemorrhage Survivors.
Castello JP, Pasi M, Kubiszewski P, Abramson JR, Charidimou A, Kourkoulis C, DiPucchio Z, Schwab K, Anderson CD, Gurol ME, Greenberg SM, Rosand J, Viswanathan A, Biffi A. Stroke. 2021 Sep 30:STROKEAHA121035488. doi: 10.1161/STROKEAHA.121.035488.


Association of cortical microstructure with amyloid-β and tau: impact on cognitive decline, neurodegeneration, and clinical progression in older adults
Rodriguez-Vieitez E, Montal V, Sepulcre J, Lois C, Hanseeuw B, Vilaplana E, Schultz AP, Properzi MJ, Scott MR, Amariglio R, Papp KV, Marshall GA, Fortea J, Johnson KA, Sperling RA, Vannini P. Mol Psychiatry. 2021 Sep 29. doi: 10.1038/s41380-021-01290-z.


Evolving phenotypes of non-hospitalized patients that indicate long COVID.
Estiri H, Strasser ZH, Brat GA, Semenov YR; Consortium for Characterization of COVID-19 by EHR (4CE), Patel CJ, Murphy SN. BMC Med. 2021 Sep 27;19(1):249. doi: 10.1186/s12916-021-02115-0.


Physiological Assessment of Delirium Severity: The Electroencephalographic Confusion Assessment Method Severity Score (E-CAM-S).
van Sleuwen M, Sun H, Eckhardt C, Neelagiri A, Tesh RA, Westmeijer M, Paixao L, Rajan S, Velpula Krishnamurthy P, Sikka P, Leone MJ, Panneerselvam E, Quadri SA, Akeju O, Kimchi EY, Westover MB. Crit Care Med. 2021 Sep 24. doi: 10.1097/CCM.0000000000005224.


Shedding Light on the Causes and Characteristics of Stroke in Lebanon: A Systematic Review of Literature.
Gifford A, Biffi A, Gelaye B, Chemali Z. J Geriatr Psychiatry Neurol. 2021 Sep 23:8919887211044753. doi: 10.1177/08919887211044753.


In vivo and neuropathology data support locus coeruleus integrity as indicator of Alzheimer's disease pathology and cognitive decline.
Jacobs HIL, Becker JA, Kwong K, Engels-Domínguez N, Prokopiou PC, Papp KV, Properzi M, Hampton OL, d'Oleire Uquillas F, Sanchez JS, Rentz DM, El Fakhri G, Normandin MD, Price JC, Bennett DA, Sperling RA, Johnson KA. Sci Transl Med. 2021 Sep 22;13(612):eabj2511. doi: 10.1126/scitranslmed.abj2511


Epilepsy stigma in the Republic of Guinea and its socioeconomic and clinical associations: A cross-sectional analysis.
Rice DR, Cisse FA, Djibo Hamani AB, Tassiou NR, Sakadi F, Bah AK, Othon GC, Conde ML, Diawara K, Traoré M, Doumbouya I, Koudaye C, Mateen FJ; Guinea Epilepsy Project. Epilepsy Res. 2021 Sep 21;177:106770. doi: 10.1016/j.eplepsyres.2021.106770.


Increased Blood Pressure Variability and the Risk of Probable Dementia or Mild Cognitive Impairment: A Post Hoc Analysis of the SPRINT MIND Trial.
de Havenon A, Anadani M, Prabhakaran S, Wong KH, Yaghi S, Rost N. J Am Heart Assoc. 2021 Sep 21;10(18):e022206. doi: 10.1161/JAHA.121.022206.


Reemergence of the language network during recovery from severe traumatic brain injury: A pilot functional MRI study.
Coffey BJ, Threlkeld ZD, Foulkes AS, Bodien YG, Edlow BL. Brain Inj. 2021 Sep 21:1-11. doi: 10.1080/02699052.2021.1972455.


Chronic Relapsing Inflammatory Optic Neuropathy (CRION).
Mukharesh L, Douglas VP, Chwalisz BK. Curr Opin Ophthalmol. 2021 Sep 20. doi: 10.1097/ICU.0000000000000804.


A Research Domain Criteria Approach to Gambling Disorder and Behavioral Addictions: Decision-Making, Response Inhibition, and the Role of Cannabidiol.
Pallanti S, Marras A, Makris N. Front Psychiatry. 2021 Sep 17;12:634418. doi: 10.3389/fpsyt.2021.634418.


Investigating Language and Domain-General Processing in Neurotypicals and Individuals With Aphasia - A Functional Near-Infrared Spectroscopy Pilot Study.
Gilmore N, Yücel MA, Li X, Boas DA, Kiran S. Front Hum Neurosci. 2021 Sep 17;15:728151. doi: 10.3389/fnhum.2021.728151. eCollection 2021.


Association between Hypothyroidism Onset and Alzheimer Disease Onset in Adults with Down Syndrome.
Lai F, Mercaldo ND, Wang CM, Hersch MS, Hersch GG, Rosas HD. Brain Sci. 2021 Sep 16;11(9):1223. doi: 10.3390/brainsci11091223.


Family Perspectives on Clinical Research for Pediatric Multiple Sclerosis: Enhancing Equity.
Mandel LA, O'Donnell E, Canenguez K, Castro-Mendoza PB, Lotze T, Waubant E, Weinstock-Guttmann B, Chitnis T. J Patient Exp. 2021 Sep 15;8:23743735211039319. doi: 10.1177/23743735211039319.


Treatment of Primary CNS Lymphoma: Maximizing Clinical Benefit, Minimizing Neurotoxicity.
Song KW, Batchelor T. Curr Oncol Rep. 2021 Sep 15;23(11):132. doi: 10.1007/s11912-021-01116-9.


Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial. Parkinson Study Group SURE-PD3 Investigators, Schwarzschild MA, Ascherio A, Casaceli C, Curhan GC, Fitzgerald R, Kamp C, Lungu C, Macklin EA, Marek K, Mozaffarian D, Oakes D, Rudolph A, Shoulson I, Videnovic A, Scott B, Gauger L, Aldred J, Bixby M, Ciccarello J, Gunzler SA, Henchcliffe C, Brodsky M, Keith K, Hauser RA, Goetz C, LeDoux MS, Hinson V, Kumar R, Espay AJ, Jimenez-Shahed J, Hunter C, Christine C, Daley A, Leehey M, de Marcaida JA, Friedman JH, Hung A, Bwala G, Litvan I, Simon DK, Simuni T, Poon C, Schiess MC, Chou K, Park A, Bhatti D, Peterson C, Criswell SR, Rosenthal L, Durphy J, Shill HA, Mehta SH, Ahmed A, Deik AF, Fang JY, Stover N, Zhang L, Dewey RB Jr, Gerald A, Boyd JT, Houston E, Suski V, Mosovsky S, Cloud L, Shah BB, Saint-Hilaire M, James R, Zauber SE, Reich S, Shprecher D, Pahwa R, Langhammer A, LaFaver K, LeWitt PA, Kaminski P, Goudreau J, Russell D, Houghton DJ, Laroche A, Thomas K, McGraw M, Mari Z, Serrano C, Blindauer K, Rabin M, Kurlan R, Morgan JC, Soileau M, Ainslie M, Bodis-Wollner I, Schneider RB, Waters C, Ratel AS, Beck CA, Bolger P, Callahan KF, Crotty GF, Klements D, Kostrzebski M, McMahon GM, Pothier L, Waikar SS, Lang A, Mestre T. JAMA. 2021 Sep 14;326(10):926-939. doi: 10.1001/jama.2021.10207.


A category-selective semantic memory deficit for animate objects in semantic variant primary progressive aphasia.
Henderson SK, Dev SI, Ezzo R, Quimby M, Wong B, Brickhouse M, Hochberg D, Touroutoglou A, Dickerson BC, Cordella C, Collins JA. Brain Commun. 2021 Sep 14;3(4):fcab210. doi: 10.1093/braincomms/fcab210.


Diazepam induced sleep spindle increase correlates with cognitive recovery in a child with epileptic encephalopathy. Stoyell SM, Baxter BS, McLaren J, Kwon H, Chinappen DM, Ostrowski L, Zhu L, Grieco JA, Kramer MA, Morgan AK, Emerton BC, Manoach DS, Chu CJ. BMC Neurol. 2021 Sep 14;21(1):355. doi: 10.1186/s12883-021-02376-5.


Radiomic signature of DWI-FLAIR mismatch in large vessel occlusion stroke.
Regenhardt RW, Bretzner M, Zanon Zotin MC, Bonkhoff AK, Etherton MR, Hong S, Das AS, Alotaibi NM, Vranic JE, Dmytriw AA, Stapleton CJ, Patel AB, Kuchcinski G, Rost NS, Leslie-Mazwi TM. J Neuroimaging. 2021 Sep 10. doi: 10.1111/jon.12928.


Excessive White Matter Hyperintensity Increases Susceptibility to Poor Functional Outcomes After Acute Ischemic Stroke.
Hong S, Giese AK, Schirmer MD, Bonkhoff AK, Bretzner M, Rist P, Dalca AV, Regenhardt RW, Etherton MR, Donahue KL, Nardin M, Mocking SJT, McIntosh EC, Attia J, Benavente OR, Cole JW, Donatti A, Griessenauer CJ, Heitsch L, Holmegaard L, Jood K, Jimenez-Conde J, Roquer J, Kittner SJ, Lemmens R, Levi CR, McDonough CW, Meschia JF, Phuah CL, Rolfs A, Ropele S, Rosand J, Rundek T, Sacco RL, Schmidt R, Enzinger C, Sharma P, Slowik A, Sousa A, Stanne TM, Strbian D, Tatlisumak T, Thijs V, Vagal A, Wasselius J, Woo D, Zand R, McArdle PF, Worrall BB, Wu O, Jern C, Lindgren AG, Maguire J, Tomppo L, Golland P, Rost NS; MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium. Front Neurol. 2021 Sep 10;12:700616. doi: 10.3389/fneur.2021.700616. eCollection 2021.


A Longitudinal Analysis of Early Lesion Growth in Presymptomatic Patients with Cerebral Adrenoleukodystrophy.
Mallack EJ, Askin G, van de Stadt S, Caruso PA, Musolino PL, Engelen M, Niogi SN, Eichler FS. AJNR Am J Neuroradiol. 2021 Sep 9. doi: 10.3174/ajnr.A7250.


Intracerebral hemorrhage and small vessel disease.
Li Q, Wang ZJ, Viswanathan A. Chin Med J (Engl). 2021 Sep 9. doi: 10.1097/CM9.0000000000001620.


A Primer on EEG Spectrograms.
Ng MC, Jing J, Westover MB. J Clin Neurophysiol. 2021 Sep 8. doi: 10.1097/WNP.0000000000000736.


Impact of Sterilization Methods on the Seeding Ability of Human Tau Proteopathic Seeds.
Fernandes AR, Dujardin S, Maté de Gérando A, Hyman BT, Frosch MP. J Neuropathol Exp Neurol. 2021 Sep 8:nlab087. doi: 10.1093/jnen/nlab087.


Association of External Ventricular Drain Wean Strategy with Shunt Placement and Length of Stay in Subarachnoid Hemorrhage: A Prospective Multicenter Study.
Chung DY, Thompson BB, Kumar MA, Mahta A, Rao SS, Lai JH, Tadevosyan A, Kessler K, Locascio JJ, Patel AB, Mohamed W, Olson DM, John S, Rordorf GA. Neurocrit Care. 2021 Sep 8. doi: 10.1007/s12028-021-01343-9.


The Utility of Quantitative EEG in Detecting Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage.
Baang HY, Chen HY, Herman AL, Gilmore EJ, Hirsch LJ, Sheth KN, Petersen NH, Zafar SF, Rosenthal ES, Westover MB, Kim JA. J Clin Neurophysiol. 2021 Sep 8. doi: 10.1097/WNP.0000000000000754.


Decoding the Spectrogram Rainbow.
Ng MC, Westover MB. J Clin Neurophysiol. 2021 Sep 8. doi: 10.1097/WNP.0000000000000741.


Adalimumab for CNS sarcoidosis: single-center experience and literature review.
Hutto SK, Kyle K, Cavanagh JJ, Reda H, Venna N. J Neurol. 2021 Sep 6. doi: 10.1007/s00415-021-10793-2.


Neurologic complications in patients with lymphoid cancer.
Nayak L, Batchelor TT. Blood. 2021 Sep 3:blood.2019003690. doi: 10.1182/blood.2019003690.


Influence of Common Reference Regions on Regional Tau Patterns in Cross-Sectional and Longitudinal [18F]-AV-1451 PET Data.
Young CB, Landau SM, Harrison TM, Poston KL, Mormino EC; ADNI. Neuroimage. 2021 Sep 3:118553. doi: 10.1016/j.neuroimage.2021.118553.


Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryonic stem cells.
Sadegh C, Ebina W, Arvanites AC, Davidow LS, Rubin LL, Macklis JD. PLoS One. 2021 Sep 2;16(9):e0254113. doi: 10.1371/journal.pone.0254113.


Increasing Representation of Women as Editors in Medical Journals.
Jacobs EA, Ganguli I, Inouye SK. JAMA Netw Open. 2021 Sep 1;4(9):e2123364. doi: 10.1001/jamanetworkopen.2021.23364.


The Urgent Need for Rigorous Studies of Telehealth for Older Adults Who Are Homebound.
Moo LR, Schwartz AW. JAMA Netw Open. 2021 Sep 1;4(9):e2113451. doi: 10.1001/jamanetworkopen.2021.13451.


High-Resolution Ultrasound in the Diagnosis and Surgical Management of Ulnar Neuropathy at the Elbow.
Limbekar NS, Soong MC, Vytopil MM, Blanchet DT, Paci GM, Ho DT. Orthopedics. 2021 Sep-Oct;44(5):285-288. doi: 10.3928/01477447-20210819-06


From REM to orexin: clinical progress in narcolepsy - was it worth the wait? was it worth the "weight?".
Sassower KC. Arq Neuropsiquiatr. 2021 Sep;79(9):757-758. doi: 10.1590/0004-282X-anp-2021-E009.


Association of Short and Long Sleep Duration With Amyloid-β Burden and Cognition in Aging.
Winer JR, Deters KD, Kennedy G, Jin M, Goldstein-Piekarski A, Poston KL, Mormino EC. JAMA Neurol. 2021 Aug 30. doi: 10.1001/jamaneurol.2021.2876.


Neutralizing antibody evasion and transduction with purified extracellular vesicle-enveloped AAV vectors.
Cheng M, Dietz L, Gong Y, Eichler F, Nammour J, Ng C, Grimm D, Maguire CA. Hum Gene Ther. 2021 Aug 27. doi: 10.1089/hum.2021.122.


Targeting lipid droplets for autophagic degradation by ATTEC.
Fu Y, Lu B. Autophagy. 2021 Aug 26:1-3. doi: 10.1080/15548627.2021.1967616.


EXPRESS: Idiopathic Primary Intraventricular Hemorrhage and Cerebral Small Vessel Disease. Das AS, Regenhardt RW, Gokcal E, Horn MJ, Daoud N, Schwab KM, Rost NS, Viswanathan A, Kimberly WT, Goldstein JN, Biffi A, Schwamm L, Rosand J, Greenberg SM, Gurol ME. Int J Stroke. 2021 Aug 24:17474930211043663. doi: 10.1177/17474930211043663.


High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy.
Cheng C, Reis SA, Adams ET, Fass DM, Angus SP, Stuhlmiller TJ, Richardson J, Olafson H, Wang ET, Patnaik D, Beauchamp RL, Feldman DA, Silva MC, Sur M, Johnson GL, Ramesh V, Miller BL, Temple S, Kosik KS, Dickerson BC, Haggarty SJ. Sci Rep. 2021 Aug 23;11(1):17029. doi: 10.1038/s41598-021-96227-5.


Deep learning assisted quantitative assessment of histopathological markers of Alzheimer's disease and cerebral amyloid angiopathy.
Perosa V, Scherlek AA, Kozberg MG, Smith L, Westerling-Bui T, Auger CA, Vasylechko S, Greenberg SM, van Veluw SJ. Acta Neuropathol Commun. 2021 Aug 21;9(1):141. doi: 10.1186/s40478-021-01235-1.


Vesicle trafficking and pathways to neurodegeneration.
Blackstone C, Elwood F, Plun-Favreau H, Lewis PA. Mol Neurodegener. 2021 Aug 21;16(1):56. doi: 10.1186/s13024-021-00480-1.


B-Cell Targeted Treatments for Neuromyelitis Optica Spectrum Disorder: A Focus on CD19 and CD20.
Levy M, Mealy MA. Immunotargets Ther. 2021 Aug 20;10:325-331. doi: 10.2147/ITT.S255722. eCollection 2021.


Treating epilepsy in forcibly displaced persons: timely, necessary, affordable.
Mateen FJ. Nat Rev Neurol. 2021 Aug 19. doi: 10.1038/s41582-021-00548-y.


Sleep apnea and respiratory anomaly detection from a wearable band and oxygen saturation.
Ganglberger W, Bucklin AA, Tesh RA, Da Silva Cardoso M, Sun H, Leone MJ, Paixao L, Panneerselvam E, Ye EM, Thompson BT, Akeju O, Kuller D, Thomas RJ, Westover MB. Sleep Breath. 2021 Aug 18. doi: 10.1007/s11325-021-02465-2.


Clinical Correlation Between Vertical Gaze Palsy and Midbrain Volume in Progressive Supranuclear Palsy.
Buch KA, Bouffard MA, Kardon RH, Wills AA, Privitera CM, Sharma M, Wray SH. J Neuroophthalmol. 2021 Aug 17. doi: 10.1097/WNO.0000000000001393.


Stroke Genetics: Turning Discoveries into Clinical Applications.
Dichgans M, Beaufort N, Debette S, Anderson CD. Stroke. 2021 Aug 17:STROKEAHA121032616. doi: 10.1161/STROKEAHA.121.032616.


The development and implementation of teleneuropsychology in an academic lifespan neuropsychology center: Lessons learned from the COVID-19 pandemic.
Pulsifer MB, Grieco JA, Burstein SM, Parsons MW, Gardner MM, Sherman JC. J Clin Exp Neuropsychol. 2021 Aug 13:1-12. doi: 10.1080/13803395.2021.1963683.


Retrospective Analysis of Safety and Outcomes of Rituximab for Myasthenia Gravis in Patients ≥ 65 Years Old.
Doughty CT, Suh J, David WS, Amato AA, Guidon AC. Muscle Nerve. 2021 Aug 11. doi: 10.1002/mus.27393.


Automated olfactory bulb segmentation on high resolutional T2-weighted MRI.
Estrada S, Lu R, Diers K, Zeng W, Ehses P, Stöcker T, Breteler MMB, Reuter M. Neuroimage. 2021 Aug 10;242:118464. doi: 10.1016/j.neuroimage.2021.118464.


Electronic pill bottles to monitor and promote medication adherence for people with multiple sclerosis: A randomized, virtual clinical trial.
Rice DR, Kaplan TB, Hotan GC, Vogel AC, Matiello M, Gillani RL, Hutto SK, Ham AS, Klawiter EC, George IC, Galetta K, Mateen FJ. J Neurol Sci. 2021 Aug 8;428:117612. doi: 10.1016/j.jns.2021.117612.


Preliminary Neurocognitive Results Post Hypoglossal Nerve Stimulation in Patients With Down Syndrome.
Grieco JA, Hartnick CJ, Skotko BG, Yu PK, Pulsifer MB. Laryngoscope. 2021 Aug 7. doi: 10.1002/lary.29808.


National Trends in Telestroke Utilization in a US Commercial Platform Prior to the COVID-19 Pandemic.
Zachrison KS, Sharma R, Wang Y, Mehrotra A, Schwamm LH. J Stroke Cerebrovasc Dis. 2021 Aug 7;30(10):106035. doi: 10.1016/j.jstrokecerebrovasdis.2021.106035.


Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions.
Pereira JD, DuBreuil DM, Devlin AC, Held A, Sapir Y, Berezovski E, Hawrot J, Dorfman K, Chander V, Wainger BJ. Nat Commun. 2021 Aug 6;12(1):4744. doi: 10.1038/s41467-021-24776-4.


De novo DNA methyltransferases DNMT3A and DNMT3B are essential for XIST silencing for erosion of dosage compensation in pluripotent stem cells.
Fukuda A, Hazelbaker DZ, Motosugi N, Hao J, Limone F, Beccard A, Mazzucato P, Messana A, Okada C, San Juan IG, Qian M, Umezawa A, Akutsu H, Barrett LE, Eggan K. Stem Cell Reports. 2021 Aug 5:S2213-6711(21)00381-7. doi: 10.1016/j.stemcr.2021.07.015.


The neuroethics of disorders of consciousness: a brief history of evolving ideas.
Young MJ, Bodien YG, Giacino JT, Fins JJ, Truog RD, Hochberg LR, Edlow BL. Brain. 2021 Aug 4:awab290. doi: 10.1093/brain/awab290


Reader Response: Critical Illness-Associated Cerebral Microbleeds in COVID-19 Acute Respiratory Distress Syndrome.
Edlow BL, Conklin J, Huang SY. Neurology. 2021 Aug 3;97(5):254. doi: 10.1212/WNL.0000000000012364.


Corrigendum to "Stress, resilience, and coping strategies in a sample of community-dwelling older adults during COVID-19" [J. Psychiatr. Res. 138 (2021) 176-185].
Vannini P, Gagliardi GP, Kuppe M, Dossett ML, Donovan NJ, Gatchel JR, Quiroz YT, Premnath PY, Amariglio R, Sperling RA, Marshall GA. J Psychiatr Res. 2021 Aug 3;142:167-170. doi: 10.1016/j.jpsychires.2021.07.045.


Dopaminergic modulation of human consciousness via default mode network connectivity.
Edlow BL. Proc Natl Acad Sci U S A. 2021 Aug 3;118(31):e2111268118. doi: 10.1073/pnas.2111268118.


Association Between Hospital Volumes and Clinical Outcomes for Patients With Nontraumatic Subarachnoid Hemorrhage.
Leifer D, Fonarow GC, Hellkamp A, Baker D, Hoh BL, Prabhakaran S, Schoeberl M, Suter R, Washington C, Williams S, Xian Y, Schwamm LH. J Am Heart Assoc. 2021 Aug 3;10(15):e018373. doi: 10.1161/JAHA.120.018373


Association of Social Support With Brain Volume and Cognition.
Salinas J, O'Donnell A, Kojis DJ, Pase MP, DeCarli C, Rentz DM, Berkman LF, Beiser A, Seshadri S. JAMA Netw Open. 2021 Aug 2;4(8):e2121122. doi: 10.1001/jamanetworkopen.2021.21122.


Microscale dynamics of electrophysiological markers of epilepsy.
Yang JC, Paulk AC, Salami P, Lee SH, Ganji M, Soper DJ, Cleary D, Simon M, Maus D, Lee JW, Nahed BV, Jones PS, Cahill DP, Cosgrove GR, Chu CJ, Williams Z, Halgren E, Dayeh S, Cash SS. Clin Neurophysiol. 2021 Aug 2:S1388-2457(21)00670-2. doi: 10.1016/j.clinph.2021.06.024.


Patient-reported safety and tolerability of the COVID-19 vaccines in persons with rare neuroimmunological diseases.
Lotan I, Romanow G, Levy M. Mult Scler Relat Disord. 2021 Aug 2;55:103189. doi: 10.1016/j.msard.2021.103189.


Radiologically isolated syndrome: A single-center, retrospective cohort study.
George IC, Rice DR, Chibnik LB, Mateen FJ. Mult Scler Relat Disord. 2021 Aug 2;55:103183. doi: 10.1016/j.msard.2021.103183.


Detection of Leptomeningeal Disease Using Cell-Free DNA From Cerebrospinal Fluid.
White MD, Klein RH, Shaw B, Kim A, Subramanian M, Mora JL, Giobbie-Hurder A, Nagabhushan D, Jain A, Singh M, Kuter BM, Nayyar N, Bertalan MS, Stocking JH, Markson SC, Lastrapes M, Alvarez-Breckenridge C, Cahill DP, Gydush G, Rhoades J, Rotem D, Adalsteinsson VA, Mahar M, Kaplan A, Oh K, Sullivan RJ, Gerstner E, Carter SL, Brastianos PK. JAMA Netw Open. 2021 Aug 2;4(8):e2120040. doi: 10.1001/jamanetworkopen.2021.20040.


The Changing Face of Osmotic Demyelination Syndrome: A Retrospective, Observational Cohort Study.
Fitts W, Vogel AC, Mateen FJ. Neurol Clin Pract. 2021 Aug;11(4):304-310. doi: 10.1212/CPJ.0000000000000932.


Radicava/Edaravone Findings in Biomarkers From Amyotrophic Lateral Sclerosis (REFINE-ALS): Protocol and Study Design.
Berry J, Brooks B, Genge A, Heiman-Patterson T, Appel S, Benatar M, Bowser R, Cudkowicz M, Gooch C, Shefner J, Westra J, Agnese W, Merrill C, Nelson S, Apple S. Neurol Clin Pract. 2021 Aug;11(4):e472-e479. doi: 10.1212/CPJ.0000000000000968.


Telehealth Disparities: The Authors Reply.
Rodriguez JA, Bates DW, Samal L, Saadi A, Schwamm LH. Health Aff (Millwood). 2021 Aug;40(8):1340. doi: 10.1377/hlthaff.2021.01041.


Palliative Care for Polio and Postpolio Syndrome.
Rhee JY, Brizzi K. Phys Med Rehabil Clin N Am. 2021 Aug;32(3):569-579. doi: 10.1016/j.pmr.2021.02.008.


Case 292: Lyme Neuroborreliosis.
Douglas VP, Douglas KAA, Reinshagen KL, Chwalisz BK. Radiology. 2021 Aug;300(2):484-488. doi: 10.1148/radiol.2021201715.


'Drip-and-ship' intravenous thrombolysis and outcomes for large vessel occlusion thrombectomy candidates in a hub-and-spoke telestroke model.
Regenhardt RW, Rosenthal JA, Awad A, Martinez-Gutierrez JC, Nolan NM, McIntyre JA, Whitney C, Alotaibi NM, Dmytriw AA, Vranic JE, Stapleton CJ, Patel AB, Rost NS, Schwamm LH, Leslie-Mazwi TM. J Neurointerv Surg. 2021 Jul 29:neurintsurg-2021-017819. doi: 10.1136/neurintsurg-2021-017819.


Knowledge assessment and psychological impact of genetic counseling in people at risk for familial FTD.
Wong B, Lucente D, Krivensky S, Krahn E, Karlawish J, Dickerson BC. Alzheimers Dement (Amst). 2021 Jul 28;13(1):e12225. doi: 10.1002/dad2.12225.


Multimorbidity networks associated with frailty among middle aged and older people with HIV.
Lorenz DR, Mukerji SS, Misra V, Uno H, Gelman BB, Moore DJ, Singer EJ, Morgello S, Gabuzda D. AIDS. 2021 Jul 28. doi: 10.1097/QAD.0000000000003040.


Opinion & Special Articles: Preventive Neurology: An Emerging Field Toward Brain Health.
Sabayan B, Isaacson R, Rost N. Neurology. 2021 Jul 27:10.1212/WNL.0000000000012554. doi: 10.1212/WNL.0000000000012554.


COVID-19 vaccine hesitancy in multiple sclerosis: A cross-sectional survey.
Uhr L, Mateen FJ. Mult Scler. 2021 Jul 27:13524585211030647. doi: 10.1177/13524585211030647.


Seizure Prophylaxis After Spontaneous Intracerebral Hemorrhage.
Jones FJS, Sanches PR, Smith JR, Zafar SF, Blacker D, Hsu J, Schwamm LH, Newhouse JP, Westover MB, Moura LMVR. JAMA Neurol. 2021 Jul 26. doi: 10.1001/jamaneurol.2021.2249.


Free-Living Motor Activity Monitoring in Ataxia-Telangiectasia.
Khan NC, Pandey V, Gajos KZ, Gupta AS. Cerebellum. 2021 Jul 24:1-12. doi: 10.1007/s12311-021-01306-y.


Systematic review of human post-mortem immunohistochemical studies and bioinformatics analyses unveil the complexity of astrocyte reaction in Alzheimer's disease.
de Navas LV, Noori A, Merrill E, Das S, Hyman BT, Serrano-Pozo A. Neuropathol Appl Neurobiol. 2021 Jul 23. doi: 10.1111/nan.12753.


Treat or Retreat: Reasons for Deferral of Endovascular Therapy for Large Vessel Occlusion Stroke.
Camargo E, Jadhav AP. Stroke. 2021 Jul 22:STROKEAHA121034361. doi: 10.1161/STROKEAHA.121.034361.


Impaired Cerebrovascular Reactivity in Huntington's Disease.
Chan ST, Mercaldo ND, Kwong KK, Hersch SM, Rosas HD. Front Physiol. 2021 Jul 21;12:663898. doi: 10.3389/fphys.2021.663898.


Current advances in digital cognitive assessment for preclinical Alzheimer's disease.
Öhman F, Hassenstab J, Berron D, Schöll M, Papp KV. Alzheimers Dement (Amst). 2021 Jul 20;13(1):e12217. doi: 10.1002/dad2.12217.


Reply: Looking beyond indirect lesion network mapping of prosopagnosia: direct measures required.
Cohen AL, Fox MD. Brain. 2021 Jul 17:awab277. doi: 10.1093/brain/awab277.


Opinion & Special Articles: Maximizing Inclusiveness and Diversity Through Virtual Residency Applications and Interviews.
Budhu J, Velazquez AI, Said RR, Jordan JT. Neurology. 2021 Jul 15:10.1212/WNL.0000000000012487. doi: 10.1212/WNL.0000000000012487.


Association between Inflammatory Conditions and Alzheimer's Disease Age of Onset in Down Syndrome.
Lai F, Mercaldo N, Wang CM, Hersch GG, Rosas HD. J Clin Med. 2021 Jul 15;10(14):3116. doi: 10.3390/jcm10143116.


FAIRSCAPE: a Framework for FAIR and Reproducible Biomedical Analytics.
Levinson MA, Niestroy J, Al Manir S, Fairchild K, Lake DE, Moorman JR, Clark T. Neuroinformatics. 2021 Jul 15. doi: 10.1007/s12021-021-09529-4.


Freedom of Speech.
Hochberg LR, Cash SS. N Engl J Med. 2021 Jul 15;385(3):278-279. doi: 10.1056/NEJMe2106392.


CLN3, at the crossroads of endocytic trafficking.
Cotman SL, Lefrancois S. Neurosci Lett. 2021 Jul 15:136117. doi: 10.1016/j.neulet.2021.136117.


FDA Approval of Aduhelm Paves a New Path for Alzheimer's Disease.
Tanzi RE. ACS Chem Neurosci. 2021 Jul 14. doi: 10.1021/acschemneuro.1c00394.


Validation of an internationally derived patient severity phenotype to support COVID-19 analytics from electronic health record data.
Klann JG, Estiri H, Weber GM, Moal B, Avillach P, Hong C, Tan ALM, Beaulieu-Jones BK, Castro V, Maulhardt T, Geva A, Malovini A, South AM, Visweswaran S, Morris M, Samayamuthu MJ, Omenn GS, Ngiam KY, Mandl KD, Boeker M, Olson KL, Mowery DL, Follett RW, Hanauer DA, Bellazzi R, Moore JH, Loh NW, Bell DS, Wagholikar KB, Chiovato L, Tibollo V, Rieg S, Li ALLJ, Jouhet V, Schriver E, Xia Z, Hutch M, Luo Y, Kohane IS; Consortium for Clinical Characterization of COVID-19 by EHR (4CE) (CONSORTIA AUTHOR), Brat GA, Murphy SN. J Am Med Inform Assoc. 2021 Jul 14;28(7):1411-1420. doi: 10.1093/jamia/ocab018.


MRI Radiomic Signature of White Matter Hyperintensities Is Associated With Clinical Phenotypes.
Bretzner M, Bonkhoff AK, Schirmer MD, Hong S, Dalca AV, Donahue KL, Giese AK, Etherton MR, Rist PM, Nardin M, Marinescu R, Wang C, Regenhardt RW, Leclerc X, Lopes R, Benavente OR, Cole JW, Donatti A, Griessenauer CJ, Heitsch L, Holmegaard L, Jood K, Jimenez-Conde J, Kittner SJ, Lemmens R, Levi CR, McArdle PF, McDonough CW, Meschia JF, Phuah CL, Rolfs A, Ropele S, Rosand J, Roquer J, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Sousa A, Stanne TM, Strbian D, Tatlisumak T, Thijs V, Vagal A, Wasselius J, Woo D, Wu O, Zand R, Worrall BB, Maguire JM, Lindgren A, Jern C, Golland P, Kuchcinski G, Rost NS. Front Neurosci. 2021 Jul 12;15:691244. doi: 10.3389/fnins.2021.691244.


Intracranial pressure spikes trigger spreading depolarizations.
Oka F, Sadeghian H, Yaseen MA, Fu B, Kura S, Qin T, Sakadžić S, Sugimoto K, Inoue T, Ishihara H, Nomura S, Suzuki M, Ayata C. Brain. 2021 Jul 10:awab256. doi: 10.1093/brain/awab256.


Brain stimulation and brain lesions converge on common causal circuits in neuropsychiatric disease.
Siddiqi SH, Schaper FLWVJ, Horn A, Hsu J, Padmanabhan JL, Brodtmann A, Cash RFH, Corbetta M, Choi KS, Dougherty DD, Egorova N, Fitzgerald PB, George MS, Gozzi SA, Irmen F, Kuhn AA, Johnson KA, Naidech AM, Pascual-Leone A, Phan TG, Rouhl RPW, Taylor SF, Voss JL, Zalesky A, Grafman JH, Mayberg HS, Fox MD. Nat Hum Behav. 2021 Jul 8. doi: 10.1038/s41562-021-01161-1.


The Long-Term Public Health Impact of Social Distancing on Brain Health: Topical Review.
Kumar A, Salinas J. Int J Environ Res Public Health. 2021 Jul 8;18(14):7307. doi: 10.3390/ijerph18147307.


Therapies to Restore Consciousness in Patients with Severe Brain Injuries: A Gap Analysis and Future Directions.
Edlow BL, Sanz LRD, Polizzotto L, Pouratian N, Rolston JD, Snider SB, Thibaut A, Stevens RD, Gosseries O; Curing Coma Campaign and its contributing members. Neurocrit Care. 2021 Jul;35(Suppl 1):68-85. doi: 10.1007/s12028-021-01227-y. Epub Jul 8.


The Long-Term Public Health Impact of Social Distancing on Brain Health: Topical Review.
Kumar A, Salinas J. Int J Environ Res Public Health. 2021 Jul 8;18(14):7307. doi: 10.3390/ijerph18147307.


Genome-encoded cytoplasmic double-stranded RNAs, found in C9ORF72 ALS-FTD brain, propagate neuronal loss.
Rodriguez S, Sahin A, Schrank BR, Al-Lawati H, Costantino I, Benz E, Fard D, Albers AD, Cao L, Gomez AC, Evans K, Ratti E, Cudkowicz M, Frosch MP, Talkowski M, Sorger PK, Hyman BT, Albers MW. Sci Transl Med. 2021 Jul 7;13(601):eaaz4699. doi: 10.1126/scitranslmed.aaz4699.


Automated annotation of epileptiform burden and its association with outcomes.
Zafar SF, Rosenthal ES, Jing J, Ge W, Tabaeizadeh M, Aboul Nour H, Shoukat M, Sun H, Javed F, Kassa S, Edhi M, Bordbar E, Gallagher J, Moura V, Ghanta M, Shao YP, An S, Sun J, Cole AJ, Westover MB. Ann Neurol. 2021 Jul 7. doi: 10.1002/ana.26161.


A Model of Metabolic Supply-Demand Mismatch Leading to Secondary Brain Injury.
Song J, Kim JA, Struck AF, Zhang R, Westover MB. J Neurophysiol. 2021 Jul 7. doi: 10.1152/jn.00674.2020.


Mapping a memory disorder using functional network analysis.
Edlow BL. Acta Neurol Scand. 2021 Jul 6. doi: 10.1111/ane.13494.


Enhancing Neurofibromatosis Clinical Trial Outcome Measures Through Patient Engagement: Lessons From REiNS.
Merker VL, Lessing AJ, Moss I, Hussey M, Oberlander B, Rose T, Thalheimer R, Wirtanen T, Wolters PL, Gross AM, Plotkin SR; REiNS International Collaboration. Neurology. 2021 Jul 6:10.1212/WNL.0000000000012430. doi: 10.1212/WNL.0000000000012430.


Role of Interleukin-1 Receptor-Like 1 (ST2) in Cerebrovascular Disease.
Sastre C, Bevers MB, Kimberly WT. Neurocrit Care. 2021 Jul 6. doi: 10.1007/s12028-021-01284-3.  


Off-label use of aducanumab for cerebral amyloid angiopathy.
Greenberg SM, Cordonnier C, Schneider JA, Smith EE, van Buchem MA, van Veluw SJ, Verbeek MM, Viswanathan A, Werring DJ. Lancet Neurol. 2021 Jul 5:S1474-4422(21)00213-1. doi: 10.1016/S1474-4422(21)00213-1.


Fenfluramine for seizures associated with Sunflower syndrome.
Geenen KR, Doshi SP, Patel S, Sourbron J, Falk A, Morgan A, Vu U, Bruno PL, Thiele EA. Dev Med Child Neurol. 2021 Jul 3. doi: 10.1111/dmcn.14965.


Characterization of mononeuropathy of the lateral cutaneous nerve of the calf.
Oaklander AL, Van Houten T, Sabouri AS. Muscle Nerve. 2021 Jul 1. doi: 10.1002/mus.27367.


Finding a Place for Candidate Gene Studies in a Genome-Wide Association Study World.
Menon DK, Rosand J. JAMA Netw Open. 2021 Jul 1;4(7):e2118594. doi: 10.1001/jamanetworkopen.2021.18594.


Helping the Public Understand Adverse Events Associated With COVID-19 Vaccinations: Lessons Learned From Functional Neurological Disorder.
Kim DD, Kung CS, Perez DL. JAMA Neurol. 2021 Jul 1;78(7):789-790. doi: 10.1001/jamaneurol.2021.1042.


Clinical Electroencephalography Findings and Considerations in Hospitalized Patients With Coronavirus SARS-CoV-2.
Ayub N, Cohen J, Jing J, Jain A, Tesh R, Mukerji SS, Zafar SF, Westover MB, Kimchi EY. Neurohospitalist. 2021 Jul;11(3):204-213. doi: 10.1177/1941874420972237.


Teleneurology Comprehensive Inpatient Consultations Expedite Access to Care and Decreases Hospital Length of Stay.
McCormick R, Estrada J, Whitney C, Hinrichsen M, Lee PT, Cohen AB, Schwamm L, Matiello M. Neurohospitalist. 2021 Jul;11(3):229-234. doi: 10.1177/19418744211000951.


Putting memory complaints in context matters.
Amariglio R. Int Psychogeriatr. 2021 Jul;33(7):645-646. doi: 10.1017/S1041610220001672.


Diffuse Cerebral Edema After Moyamoya Disease-Related Intracerebral Hemorrhage: A Case Report.
Das AS, Regenhardt RW, Patel N, Feske SK, Bevers MB, Vaitkevicius H, Izzy S. Neurohospitalist. 2021 Jul;11(3):251-254. doi: 10.1177/1941874420980611.


Consensus disease definitions for neurologic immune-related adverse events of immune checkpoint inhibitors.
Guidon AC, Burton LB, Chwalisz BK, Hillis J, Schaller TH, Amato AA, Betof Warner A, Brastianos PK, Cho TA, Clardy SL, Cohen JV, Dietrich J, Dougan M, Doughty CT, Dubey D, Gelfand JM, Guptill JT, Johnson DB, Juel VC, Kadish R, Kolb N, LeBoeuf NR, Linnoila J, Mammen AL, Martinez-Lage M, Mooradian MJ, Naidoo J, Neilan TG, Reardon DA, Rubin KM, Santomasso BD, Sullivan RJ, Wang N, Woodman K, Zubiri L, Louv WC, Reynolds KL. J Immunother Cancer. 2021 Jul;9(7):e002890. doi: 10.1136/jitc-2021-002890.


Greater Neural Differentiation in the Ventral Visual Cortex Is Associated with Youthful Memory in Superaging.
Katsumi Y, Andreano JM, Barrett LF, Dickerson BC, Touroutoglou A. Cereb Cortex. 2021 Jun 30:bhab157. doi: 10.1093/cercor/bhab157.


Solriamfetol for Excessive Daytime Sleepiness in Parkinson's Disease: Phase 2 Proof-of-Concept Trial.
Videnovic A, Amara AW, Comella C, Schweitzer PK, Emsellem H, Liu K, Sterkel AL, Gottwald MD, Steinerman JR, Jochelson P, Zomorodi K, Hauser RA. Mov Disord. 2021 Jun 30. doi: 10.1002/mds.28702.


A Neural Circuit for Spirituality and Religiosity Derived From Patients With Brain Lesions.
Ferguson MA, Schaper FLWVJ, Cohen A, Siddiqi S, Merrill SM, Nielsen JA, Grafman J, Urgesi C, Fabbro F, Fox MD. Biol Psychiatry. 2021 Jun 29:S0006-3223(21)01403-7. doi: 10.1016/j.biopsych.2021.06.016.


Clinical Reasoning: A 28-Year-Old Woman With Vision Loss and an Unusual Gait.
Dohlman JC, Chwalisz BK, Stephen CD. Neurology. 2021 Jun 29:10.1212/WNL.0000000000012446. doi: 10.1212/WNL.0000000000012446.


SNO and EANO practice guideline update: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors.
Walbert T, Harrison RA, Schiff D, Avila EK, Chen M, Kandula P, Lee JW, Le Rhun E, Stevens GHJ, Vogelbaum MA, Wick W, Weller M, Wen PY, Gerstner ER. Neuro Oncol. 2021 Jun 26:noab152. doi: 10.1093/neuonc/noab152.


Building clinically relevant outcomes across the Alzheimer's disease spectrum.
Rentz DM, Wessels AM, Annapragada AV, Berger AK, Edgar CJ, Gold M, Miller DS, Randolph C, Ryan JM, Wunderlich G, Zoschg MC, Trépel D, Knopman DS, Staffaroni AM, Bain LJ, Carrillo MC, Weber CJ. Alzheimers Dement (N Y). 2021 Jun 26;7(1):e12181. doi: 10.1002/trc2.12181.


Pathological correlates of impaired self-awareness of memory function in Alzheimer's disease.
Gagliardi G, Kuppe M, Lois C, Hanseeuw B, Vannini P; Alzheimer’s Disease Neuroimaging Initiative. Alzheimers Res Ther. 2021 Jun 25;13(1):118. doi: 10.1186/s13195-021-00856-x.


Early Brain Injury and Soluble ST2 After Nontraumatic Subarachnoid Hemorrhage.
Schleicher RL, Bevers MB, Rubin DB, Koch MJ, Bache S, Lissak IA, Patel AB, Rosenthal ES, Møller K, Kimberly WT. Stroke. 2021 Jun 25:STROKEAHA121035372. doi: 10.1161/STROKEAHA.121.035372.


Huntington's disease: Nearly four decades of human molecular genetics.
Gusella JF, Lee JM, MacDonald ME. Hum Mol Genet. 2021 Jun 24:ddab170. doi: 10.1093/hmg/ddab170.


Psychiatry's modern role in functional neurological disorder: join the renaissance.
Bègue I, Nicholson TR, Kozlowska K, LaFrance WC, Levenson JL, Rapaport MH, Carson AJ, Perez DL. Psychol Med. 2021 Jun 24:1-3.


Review of Phase III Clinical Trials Outcomes in Patients with Secondary Progressive Multiple Sclerosis.
McAdams M, Stankiewicz JM, Weiner HL, Chitnis T. Mult Scler Relat Disord. 2021 Jun 24;54:103086. doi: 10.1016/j.msard.2021.103086.


Plasma IL-12/IFN-γ axis predicts cognitive trajectories in cognitively unimpaired older adults.
Yang HS, Zhang C, Carlyle BC, Zhen SY, Trombetta BA, Schultz AP, Pruzin JJ, Fitzpatrick CD, Yau WW, Kirn DR, Rentz DM, Arnold SE, Johnson KA, Sperling RA, Chhatwal JP, Tanzi RE. Alzheimers Dement. 2021 Jun 23. doi: 10.1002/alz.12399.


Association Analysis of Chromosome X to Identify Genetic Modifiers of Huntington's Disease.
Hong EP, Chao MJ, Massey T, McAllister B, Lobanov S, Jones L, Holmans P, Kwak S, Orth M, Ciosi M, Monckton DG, Long JD, Lucente D, Wheeler VC, MacDonald ME, Gusella JF, Lee JM. J Huntingtons Dis. 2021 Jun 22. doi: 10.3233/JHD-210485.


Obtusaquinone: A Cysteine-Modifying Compound That Targets Keap1 for Degradation.
Badr CE, da Hora CC, Kirov AB, Tabet E, Amante R, Maksoud S, Nibbs AE, Fitzsimons E, Boukhali M, Chen JW, Chiu NHL, Nakano I, Haas W, Mazitschek R, Tannous BA. ACS Chem Biol. 2020 Jun 19;15(6):1445-1454. doi: 10.1021/acschembio.0c00104.


Do Triphasic Waves and Nonconvulsive Status Epilepticus Arise From Similar Mechanisms? A Computational Model.
Ligtenstein S, Song J, Jin J, Sun H, Paixao L, Zafar S, Westover MB. J Clin Neurophysiol. 2021 Jun 18. doi: 10.1097/WNP.0000000000000719


Computational Evidence for a Competitive Thalamocortical Model of Spikes and Spindle Activity in Rolandic Epilepsy.
Li Q, Westover MB, Zhang R, Chu CJ. Front Comput Neurosci. 2021 Jun 18;15:680549. doi: 10.3389/fncom.2021.680549.


Clinical Reasoning: An 81-Year-Old Woman Who Insisted the Hospital Was Her Home.
Carlisle TC, Stanley MPH, Singhal AB, Caplan DN. Neurology. 2021 Jun 18:10.1212/WNL.0000000000012392. doi: 10.1212/WNL.0000000000012392.


Gait Difficulties and Postural Instability in Adrenoleukodystrophy.
Godbole NP, Sadjadi R, DeBono MA, Grant NR, Kelly DC, James PF, Stephen CD, Balkwill MD, Lewis RF, Eichler FS. Front Neurol. 2021 Jun 17;12:684102. doi: 10.3389/fneur.2021.684102. eCollection 2021.


Evaluation of serological lateral flow assays for severe acute respiratory syndrome coronavirus-2.
Trombetta BA, Kandigian SE, Kitchen RR, Grauwet K, Webb PK, Miller GA, Jennings CG, Jain S, Miller S, Kuo Y, Sweeney T, Gilboa T, Norman M, Simmons DP, Ramirez CE, Bedard M, Fink C, Ko J, De León Peralta EJ, Watts G, Gomez-Rivas E, Davis V, Barilla RM, Wang J, Cunin P, Bates S, Morrison-Smith C, Nicholson B, Wong E, El-Mufti L, Kann M, Bolling A, Fortin B, Ventresca H, Zhou W, Pardo S, Kwock M, Hazra A, Cheng L, Ahmad QR, Toombs JA, Larson R, Pleskow H, Luo NM, Samaha C, Pandya UM, De Silva P, Zhou S, Ganhadeiro Z, Yohannes S, Gay R, Slavik J, Mukerji SS, Jarolim P, Walt DR, Carlyle BC, Ritterhouse LL, Suliman S. BMC Infect Dis. 2021 Jun 16;21(1):580. doi: 10.1186/s12879-021-06257-7.


Correction to: Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder.
Zimmerman AW, Singh K, Connors SL, Liu H, Panjwani AA, Lee LC, Diggins E, Foley A, Melnyk S, Singh IN, Jill James S, Frye RE, Fahey JW. Mol Autism. 2021 Jun 16;12(1):44. doi: 10.1186/s13229-021-00451-9.


Cognitive effects of rapid-acting treatments for resistant depression: Just adverse, or contributing to clinical efficacy?
Guinjoan SM, Bär KJ, Camprodon JA. J Psychiatr Res. 2021 Jun 15;140:512-521. doi: 10.1016/j.jpsychires.2021.06.026.


The AAV9 variant capsid AAV-F mediates widespread transgene expression in non-human primate spinal cord after intrathecal administration.
Beharry A, Gong Y, Kim J, Hanlon KS, Nammour J, Hieber K, Eichler F, Cheng M, Stemmer-Rachamimov A, Stankovic K, Welling B, Ng C, Maguire CA. Hum Gene Ther. 2021 Jun 15. doi: 10.1089/hum.2021.069.


Anticonvulsant Primary and Secondary Prophylaxis for Acute Ischemic Stroke Patients: A Decision Analysis.
Jones FJS, Sanches PR, Smith JR, Zafar SF, Hernandez-Diaz S, Blacker D, Hsu J, Schwamm LH, Westover MB, Moura LMVR. Stroke. 2021 Jun 15:STROKEAHA120033299. doi: 10.1161/STROKEAHA.120.033299.


A REDCap-based model for online interventional research: Parent sleep education in autism.
Malow BA, Galion A, Lu F, Kennedy N, Lawrence CE, Tassone A, O'Neal L, Wilson TM, Parker RA, Harris PA, Neumeyer AM. J Clin Transl Sci. 2021 Jun 14;5(1):e138. doi: 10.1017/cts.2021.798.


Patient characteristics associated with the successful transition to virtual care: Lessons learned from the first million patients.
Zachrison KS, Yan Z, Sequist T, Licurse A, Tan-McGrory A, Erskine A, Schwamm LH. J Telemed Telecare. 2021 Jun 13:1357633X211015547. doi: 10.1177/1357633X211015547.


Unexpected Findings During Double-blind Discontinuation of Acetylcholinesterase Inhibitor Medications.
Moo LR, Martinez E, Padala K, Dunay MA, Scali RR, Chen S, Thielke SM. Clin Ther. 2021 Jun 12:S0149-2918(21)00225-3. doi: 10.1016/j.clinthera.2021.05.010.


Development and Validation of a Patient-Reported Outcome Measure of Ataxia.
Schmahmann JD, Pierce S, MacMore J, L'Italien GJ. Mov Disord. 2021 Jun 11. doi: 10.1002/mds.28670.


A deep learning approach to identify gene targets of a therapeutic for human splicing disorders.
Gao D, Morini E, Salani M, Krauson AJ, Chekuri A, Sharma N, Ragavendran A, Erdin S, Logan EM, Li W, Dakka A, Narasimhan J, Zhao X, Naryshkin N, Trotta CR, Effenberger KA, Woll MG, Gabbeta V, Karp G, Yu Y, Johnson G, Paquette WD, Cutting GR, Talkowski ME, Slaugenhaupt SA. Nat Commun. 2021 Jun 7;12(1):3332. doi: 10.1038/s41467-021-23663-2.


Skeletal Muscle and Peripheral Nerve Histopathology in COVID-19.
Suh J, Mukerji SS, Collens SI, Padera RF Jr, Pinkus GS, Amato AA, Solomon IH. Neurology. 2021 Jun 7:10.1212/WNL.0000000000012344. doi: 10.1212/WNL.0000000000012344.


Outcome after acute ischemic stroke is linked to sex-specific lesion patterns.
Bonkhoff AK, Schirmer MD, Bretzner M, Hong S, Regenhardt RW, Brudfors M, Donahue KL, Nardin MJ, Dalca AV, Giese AK, Etherton MR, Hancock BL, Mocking SJT, McIntosh EC, Attia J, Benavente OR, Bevan S, Cole JW, Donatti A, Griessenauer CJ, Heitsch L, Holmegaard L, Jood K, Jimenez-Conde J, Kittner SJ, Lemmens R, Levi CR, McDonough CW, Meschia JF, Phuah CL, Rolfs A, Ropele S, Rosand J, Roquer J, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Söderholm M, Sousa A, Stanne TM, Strbian D, Tatlisumak T, Thijs V, Vagal A, Wasselius J, Woo D, Zand R, McArdle PF, Worrall BB, Jern C, Lindgren AG, Maguire J, Bzdok D, Wu O; MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium, Rost NS. Nat Commun. 2021 Jun 2;12(1):3289. doi: 10.1038/s41467-021-23492-3.


Nodular Pachymeningitis Associated With Relapsing Polychondritis and Crohn Disease Responsive to Adalimumab and Prednisone.
Hutto SK, Maher MD, Miloslavsky EM, Venna N. Neurol Neuroimmunol Neuroinflamm. 2021 Jun 2;8(5):e1022. doi: 10.1212/NXI.0000000000001022.


Outcome after acute ischemic stroke is linked to sex-specific lesion patterns.
Bonkhoff AK, Schirmer MD, Bretzner M, Hong S, Regenhardt RW, Brudfors M, Donahue KL, Nardin MJ, Dalca AV, Giese AK, Etherton MR, Hancock BL, Mocking SJT, McIntosh EC, Attia J, Benavente OR, Bevan S, Cole JW, Donatti A, Griessenauer CJ, Heitsch L, Holmegaard L, Jood K, Jimenez-Conde J, Kittner SJ, Lemmens R, Levi CR, McDonough CW, Meschia JF, Phuah CL, Rolfs A, Ropele S, Rosand J, Roquer J, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Söderholm M, Sousa A, Stanne TM, Strbian D, Tatlisumak T, Thijs V, Vagal A, Wasselius J, Woo D, Zand R, McArdle PF, Worrall BB, Jern C, Lindgren AG, Maguire J, Bzdok D, Wu O; MRI-GENIE and GISCOME Investigators and the International Stroke Genetics Consortium, Rost NS. Nat Commun. 2021 Jun 2;12(1):3289. doi: 10.1038/s41467-021-23492-3.


Effect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease: The STROKE-AF Randomized Clinical Trial.
Bernstein RA, Kamel H, Granger CB, Piccini JP, Sethi PP, Katz JM, Vives CA, Ziegler PD, Franco NC, Schwamm LH; STROKE-AF Investigators. JAMA. 2021 Jun 1;325(21):2169-2177. doi: 10.1001/jama.2021.6470.


Enhancing Aging and Ending Ageism: JAMA Network Open Call for Papers.
Inouye SK, Ganguli I, Jacobs EA. JAMA Netw Open. 2021 Jun 1;4(6):e2117621. doi: 10.1001/jamanetworkopen.2021.17621.


Dural Arteriovenous Fistula Presenting with Reversible Dementia.
Yoon JY, Regenhardt RW, Leslie-Mazwi TM. Ann Neurol. 2021 Jun 1. doi: 10.1002/ana.26138.


Legal Regulations and Institutional Policies Underlying Parental Leave in Graduate Medical Education.
Prasad S, Vaswani PA, Budhu JA, Conway SE, Kett LR, Eaton SHM, Bowley MP. J Grad Med Educ. 2021 Jun;13(3):349-354. doi: 10.4300/JGME-D-20-01083.1.


Assessment and Management of Cognitive Symptoms in Patients With Brain Tumors.
Parsons MW, Dietrich J. Am Soc Clin Oncol Educ Book. 2021 Jun;41:e90-e99. doi: 10.1200/EDBK_320813.


Factors Influencing Barriers and Facilitators to In-home Video Telehealth for Dementia Management.
Gately ME, Tickle-Degnen L, McLaren JE, Ward N, Ladin K, Moo LR. Clin Gerontol. 2021 Jun 6:1-14. doi: 10.1080/07317115.2021.1930316.


Expanding the therapeutic toolkit in functional neurological disorder: consensus recommendations for speech and language therapy.
Perez DL. J Neurol Neurosurg Psychiatry. 2021 Jul 1:jnnp-2021-327213. doi: 10.1136/jnnp-2021-327213.


An Update From the American Stroke Association and the Stroke Council.
Schwamm LH, Panagos PD, Mohl SM. Stroke. 2021 Jun;52(6):e269-e271. doi: 10.1161/STROKEAHA.121.034827.


Covid-19: a call for mobilizing geriatric expertise.
O'Hanlon S, Dhesi J, Aronson L, Inouye SK. Eur Geriatr Med. 2021 Jun;12(3):597-600. doi: 10.1007/s41999-021-00500-9.


Motor tract reorganization after acute central nervous system injury: a translational perspective.
Takase H, Regenhardt RW. Neural Regen Res. 2021 Jun;16(6):1144-1149. doi: 10.4103/1673-5374.300330.  


Decreased Basal Ganglia Volume in Cerebral Amyloid Angiopathy.
Fotiadis P, Pasi M, Charidimou A, Warren AD, Schwab KM; Alzheimer’s Disease Neuroimaging Initiative, Rosand J, van der Grond J, van Buchem MA, Viswanathan A, Gurol ME, Greenberg SM. J Stroke. 2021 May;23(2):223-233. doi: 10.5853/jos.2020.04280. Epub 2021 May 31.


Sex-specific differences in presentations and determinants of outcomes after endovascular thrombectomy for large vessel occlusion stroke.
Regenhardt RW, Turner AC, Hirsch JA, Young MJ, Alotaibi NM, Stapleton CJ, Patel AB, Leslie-Mazwi TM, Rost NS, Etherton MR. J Neurol. 2021 May 29. doi: 10.1007/s00415-021-10628-0.


The long-term efficacy of cannabidiol in the treatment of refractory epilepsy.
Patel S, Grinspoon R, Fleming B, Skirvin LA, Wade C, Wolper E, Bruno PL, Thiele EA. Epilepsia. 2021 May 29. doi: 10.1111/epi.16936.


A classification approach to estimating human circadian phase under circadian alignment from actigraphy and photometry data.
Brown LS, St Hilaire MA, McHill AW, Phillips AJK, Barger LK, Sano A, Czeisler CA, Doyle FJ 3rd, Klerman EB. J Pineal Res. 2021 May 29:e12745. doi: 10.1111/jpi.12745.


Relapse recovery in multiple sclerosis: Effect of treatment and contribution to long-term disability.
Sotiropoulos MG, Lokhande H, Healy BC, Polgar-Turcsanyi M, Glanz BI, Bakshi R, Weiner HL, Chitnis T. Mult Scler J Exp Transl Clin. 2021 May 28;7(2):20552173211015503. doi: 10.1177/20552173211015503.


Delta power robustly predicts cognitive function in Angelman syndrome.
Ostrowski LM, Spencer ER, Bird LM, Thibert R, Komorowski RW, Kramer MA, Chu CJ. Ann Clin Transl Neurol. 2021 May 28. doi: 10.1002/acn3.51385.


Location of Subcortical Microbleeds and Recovery of Consciousness After Severe Traumatic Brain Injury.
Bianciardi M, Izzy S, Rosen B, Wald LL, Edlow BL. Neurology. 2021 May 28:10.1212/WNL.0000000000012192. doi: 10.1212/WNL.0000000000012192.


Neuromyelitis Optica Spectrum Disorder: Clinical Burden and Cost of Relapses and Disease-Related Care in US Clinical Practice.
Royston M, Kielhorn A, Weycker D, Shaff M, Houde L, Tanvir I, Bhattacharyya S, Levy M. Neurol Ther. 2021 May 27. doi: 10.1007/s40120-021-00253-4.


Cognitive Impairment and Dementia After Stroke: Design and Rationale for the DISCOVERY Study.
Rost NS, Meschia JF, Gottesman R, Wruck L, Helmer K, Greenberg SM; DISCOVERY Investigators. Stroke. 2021 May 27:STROKEAHA120031611. doi: 10.1161/STROKEAHA.120.031611.


Focal Subcortical White Matter Lesions Disrupt Resting State Cortical Interhemispheric Functional Connectivity in Mice.
Aykan SA, Xie H, Lai JH, Zheng Y, Chung DY, Kura S, Anzabi M, Sugimoto K, McAllister LM, Yaseen MA, Boas DA, Whalen MJ, Sakadzic S, Ayata C. Cereb Cortex. 2021 May 25:bhab134. doi: 10.1093/cercor/bhab134.


Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder.
Zimmerman AW, Singh K, Connors SL, Liu H, Panjwani AA, Lee LC, Diggins E, Foley A, Melnyk S, Singh IN, James SJ, Frye RE, Fahey JW. Mol Autism. 2021 May 25;12(1):38. doi: 10.1186/s13229-021-00447-5.


Targeting Protein Arginine Methylation to Death.
Miller JJ. Neuro Oncol. 2021 May 25:noab123. doi: 10.1093/neuonc/noab123.


The Woven EndoBridge device for ruptured intracranial aneurysms: international multicenter experience and updated meta-analysis.
Harker P, Regenhardt RW, Alotaibi NM, Vranic J, Robertson FC, Dmytriw AA, Ku JC, Koch M, Stapleton CJ, Leslie-Mazwi TM, Serna N, Pabon B, Mejia JA, Patel AB. Neuroradiology. 2021 May 25. doi: 10.1007/s00234-021-02727-6.


Rare Missense Functional Variants at COL4A1 and COL4A2 in Sporadic Intracerebral Hemorrhage.
Chung J, Hamilton G, Kim M, Marini S, Montgomery B, Henry J, Cho AE, Brown DL, Worrall BB, Meschia JF, Silliman SL, Selim M, Tirschwell DL, Kidwell CS, Kissela B, Greenberg SM, Viswanathan A, Goldstein JN, Langefeld CD, Rannikmae K, Sudlow CL, Samarasekera N, Rodrigues M, Al-Shahi Salman R, Prendergast JGD, Harris SE, Deary I, Woo D, Rosand J, Van Agtmael T, Anderson CD. Neurology. 2021 May 24:10.1212/WNL.0000000000012227. doi: 10.1212/WNL.0000000000012227.


Teaching NeuroImages: Notched Delta and Angelman Syndrome.
Nascimento FA, Thiele EA, Thibert RL. Neurology. 2021 May 24:10.1212/WNL.0000000000012201. doi: 10.1212/WNL.0000000000012201.


Altered maturation and atypical cortical processing of spoken sentences in autism spectrum disorder.
Alho J, Bharadwaj H, Khan S, Mamashli F, Perrachione TK, Losh A, McGuiggan N, Joseph RM, Hämäläinen MS, Kenet T. Prog Neurobiol. 2021 May 22:102077.


Development and internal validation of a predictive model of cognitive decline 36 months following elective surgery.
Jones RN, Tommet D, Steingrimsson J, Racine AM, Fong TG, Gou Y, Hshieh TT, Metzger ED, Schmitt EM, Tabloski PA, Travison TG, Vasunilashorn SM, Abdeen A, Earp B, Kunze L, Lange J, Vlassakov K, Dickerson BC, Marcantonio ER, Inouye SK. Alzheimers Dement (Amst). 2021 May 21;13(1):e12201. doi: 10.1002/dad2.12201.


Telerehabilitation for Word Retrieval Deficits in Bilinguals With Aphasia: Effectiveness and Reliability as Compared to In-person Language Therapy.
Peñaloza C, Scimeca M, Gaona A, Carpenter E, Mukadam N, Gray T, Shamapant S, Kiran S. Front Neurol. 2021 May 20;12:589330. doi: 10.3389/fneur.2021.589330.


Patient-Tailored, Home-Based Non-invasive Brain Stimulation for Memory Deficits in Dementia Due to Alzheimer's Disease.
Bréchet L, Yu W, Biagi MC, Ruffini G, Gagnon M, Manor B, Pascual-Leone A. Front Neurol. 2021 May 20;12:598135. doi: 10.3389/fneur.2021.598135.


Cerebral Amyloid Angiopathy-Related Transient Focal Neurologic Episodes.
Smith EE, Charidimou A, Ayata C, Werring DJ, Greenberg SM. Neurology. 2021 May 20:10.1212/WNL.0000000000012234. doi: 10.1212/WNL.0000000000012234.


Altered connectivity of the default mode network in cognitively stable adults with Down syndrome: "Accelerated aging" or a prelude to Alzheimer's disease?
Rosas HD, Lewis LR, Mercaldo ND, Nasr S, Brickman AM, Siless V, Yassa M, Sathishkumar M, Lott I, Schupf N, Silverman W, Lai F; Alzheimer's Disease in Down Syndrome (ADDS) Consortium. Alzheimers Dement (Amst). 2021 May 20;13(1):e12105. doi: 10.1002/dad2.12105. eCollection 2021.


The natural history of Canavan disease: 23 new cases and comparison with patients from literature.
Bley A, Denecke J, Kohlschütter A, Schön G, Hischke S, Guder P, Bierhals T, Lau H, Hempel M, Eichler FS. Orphanet J Rare Dis. 2021 May 19;16(1):227. doi: 10.1186/s13023-020-01659-3.


Impact of revascularization therapies on outcome of posterior circulation ischemic stroke: The Indo-US stroke project.
Nair SS, Sylaja PN, Pandian J, Srivastava MVP, Khurana D, Kaul S, Arora D, Sarma PS, Khatter H, Singhal AB. J Neurol Sci. 2021 May 18;427:117499. doi: 10.1016/j.jns.2021.117499.


Predicting language treatment response in bilingual aphasia using neural network-based patient models.
Grasemann U, Peñaloza C, Dekhtyar M, Miikkulainen R, Kiran S. Sci Rep. 2021 May 18;11(1):10497.


Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes.
Bhattacharyya R, Black SE, Lotlikar MS, Fenn RH, Jorfi M, Kovacs DM, Tanzi RE. Cell Rep. 2021 May 18;35(7):109134. doi: 10.1016/j.celrep.2021.109134.


The impact of ocrelizumab on health-related quality of life in individuals with multiple sclerosis.
Glanz BI, Zurawski J, Casady EC, Shamah R, Weiner M, Chitnis T, Weiner HL, Healy BC. Mult Scler J Exp Transl Clin. 2021 May 18;7(2):20552173211007523. doi: 10.1177/20552173211007523.


Impact of Uncontrolled Hypertension at 3 Months After Intracerebral Hemorrhage.
Biffi A, Teo KC, Castello JP, Abramson JR, Leung IYH, Leung WCY, Wang Y, Kourkoulis C, Myserlis EP, Warren AD, Henry J, Chan KH, Cheung RTF, Ho SL, Anderson CD, Gurol ME, Viswanathan A, Greenberg SM, Lau KK, Rosand J. J Am Heart Assoc. 2021 May 15:e020392. doi: 10.1161/JAHA.120.020392.


Increased systemic HSP70B levels in spinal muscular atrophy infants.
Eichelberger EJ, Alves CRR, Zhang R, Petrillo M, Cullen P, Farwell W, Hurt JA, Staropoli JF, Swoboda KJ. Ann Clin Transl Neurol. 2021 May 15. doi: 10.1002/acn3.51377.


Cytoplasmic Mislocalization of RNA Polymerase II Subunit RPB1 in Alzheimer Disease Is Linked to Pathologic Tau.
Dickson JR, Yoon H, Frosch MP, Hyman BT. J Neuropathol Exp Neurol. 2021 May 15:nlab040. doi: 10.1093/jnen/nlab040.


Taming the Huntington's Disease Proteome: What Have We Learned?
Seeley C, Kegel-Gleason KB. J Huntingtons Dis. 2021 May 14. doi: 10.3233/JHD-200465.


Is It Time for Quotas to Achieve Racial and Ethnic Representation in Multiple Sclerosis Trials?
Mateen FJ. Front Neurol. 2021 May 13;12:680912. doi: 10.3389/fneur.2021.680912.


Effect of Patent Foramen Ovale (PFO) Closure After Stroke on Circulatory Biomarkers.
Deng W, McMullin D, Inglessis-Azuaje I, Locascio JJ, Palacios IF, Buonanno FS, Lo EH, Ning M. Neurology. 2021 May 13:10.1212/WNL.0000000000012188.


MRI Shrimp Sign in Cerebellar Progressive Multifocal Leukoencephalopathy: Description and Validation of a Novel Observation.
Adra N, Goodheart AE, Rapalino O, Caruso P, Mukerji SS, González RG, Venna N, Schmahmann JD. AJNR Am J Neuroradiol. 2021 May 13. doi: 10.3174/ajnr.A7145.


An Update From the American Stroke Association and the Stroke Council.
Schwamm LH, Panagos PD, Mohl SM. Stroke. 2021 May 13:STROKEAHA121034827. doi: 10.1161/STROKEAHA.121.034827.


Early Neurologic Recovery, Practice Pattern Variation, and the Risk of Endotracheal Intubation Following Established Status Epilepticus.
Rosenthal ES, Elm JJ, Ingles J, Rogers AJ, Terndrup TE, Holsti M, Thomas DG, Babcock L, Okada PJ, Lipsky RH, Miller JB, Hickey RW, Barra ME, Bleck TP, Cloyd JC, Silbergleit R, Lowenstein DH, Coles LD, Kapur J, Shinnar S, Chamberlain JM; Established Status Epilepticus Treatment Trial Study Group. Neurology. 2021 May 11;96(19):e2372-e2386. doi: 10.1212/WNL.0000000000011879.


Voluntary and magnetically evoked muscle contraction protocol in males with Duchenne muscular dystrophy: safety, feasibility, reliability, and validity.
Trost JP, Chen M, Stark MM, Hodges JS, Richter S, Lindsay A, Warren GL, Lowe DA, Kimberley TJ. Muscle Nerve. 2021 May 11. doi: 10.1002/mus.27323.


Wiring and plumbing: Oligodendrocyte precursors and angiogenesis in the oligovascular niche.
Arai K, Lo EH. J Cereb Blood Flow Metab. 2021 May 9:271678X211014979. doi: 10.1177/0271678X211014979.


Progress in Elucidating Pathophysiology of Mucolipidosis IV.
Misko A, Wood L, Kiselyov K, Slaugenhaupt S, Grishchuk Y. Neurosci Lett. 2021 May 6:135944. doi: 10.1016/j.neulet.2021.135944.


Responsive neurostimulation for focal motor status epilepticus.
Yang JC, Harid NM, Nascimento FA, Kokkinos V, Shaughnessy A, Lam AD, Westover MB, Leslie-Mazwi TM, Hochberg LR, Rosenthal ES, Cole AJ, Richardson RM, Cash SS. Ann Clin Transl Neurol. 2021 May 6. doi: 10.1002/acn3.51318.


Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease.
Liu G, Peng J, Liao Z, Locascio JJ, Corvol JC, Zhu F, Dong X, Maple-Grødem J, Campbell MC, Elbaz A, Lesage S, Brice A, Mangone G, Growdon JH, Hung AY, Schwarzschild MA, Hayes MT, Wills AM, Herrington TM, Ravina B, Shoulson I, Taba P, Kõks S, Beach TG, Cormier-Dequaire F, Alves G, Tysnes OB, Perlmutter JS, Heutink P, Amr SS, van Hilten JJ, Kasten M, Mollenhauer B, Trenkwalder C, Klein C, Barker RA, Williams-Gray CH, Marinus J; International Genetics of Parkinson Disease Progression (IGPP) Consortium, Scherzer CR. Nat Genet. 2021 May 6. doi: 10.1038/s41588-021-00847-6.


Telemedicine visits in myasthenia gravis: expert guidance and the myasthenia gravis core exam (MG-CE).
Guidon AC, Muppidi S, Nowak RJ, Guptill JT, Hehir MK, Ruzhansky K, Burton LB, Post D, Cutter G, Conwit R, Mejia NI, Kaminski HJ, Howard JF Jr. Muscle Nerve. 2021 May 6. doi: 10.1002/mus.27260.


Replication stress promotes cell elimination by extrusion.
Dwivedi VK, Pardo-Pastor C, Droste R, Kong JN, Tucker N, Denning DP, Rosenblatt J, Horvitz HR. Nature. 2021 May 5. doi: 10.1038/s41586-021-03526-y.


Venous Information in CT-Based Stroke Selection: The Only Way Out is Through.
Leslie-Mazwi T, Lin MP. Neurology. 2021 May 5:10.1212/WNL.0000000000012126. doi: 10.1212/WNL.0000000000012126.


Predictors of Outcomes in Patients With Mild Ischemic Stroke Symptoms: MaRISS.
Romano JG, Gardener H, Campo-Bustillo I, Khan Y, Tai S, Riley N, Smith EE, Sacco RL, Khatri P, Alger HM, Mac Grory B, Gulati D, Sangha NS, Craig JM, Olds KE, Benesch CG, Kelly AG, Brehaut SS, Kansara AC, Schwamm LH; MaRISS Investigators. Stroke. 2021 May 5:STROKEAHA120032809. doi: 10.1161/STROKEAHA.120.032809.


Clinical Reasoning: A 59-Year-Old Woman Presenting With Diplopia, Dysarthria, Right-Sided Weakness and Encephalopathy.
Manzano GS, Torre M, Luskin MR, Vaitkevicius H. Neurology. 2021 May 4:10.1212/WNL.0000000000012151. doi: 10.1212/WNL.0000000000012151.


Clinical Presentation and Management of SMART Syndrome.
Winter SF, Klein JP, Vaios EJ, Karschnia P, Lee EQ, Shih HA, Loebel F, Dietrich J. Neurology. 2021 May 4:10.1212/WNL.0000000000012150. doi: 10.1212/WNL.0000000000012150.


Expectations of Benefit in a Trial of a Candidate Disease-Modifying Treatment for Parkinson Disease.
Mestre TA, Macklin EA, Ascherio A, Ferreira JJ, Lang AE, Schwarzschild MA; Parkinson Study Group SURE-PD3 Investigators. Mov Disord. 2021 May 4. doi: 10.1002/mds.28630.


Circadian Biology and Stroke.
Lo EH, Albers GW, Dichgans M, Donnan G, Esposito E, Foster R, Howells DW, Huang YG, Ji X, Klerman EB, Lee S, Li W, Liebeskind DS, Lizasoain I, Mandeville ET, Moro MA, Ning M, Ray D, Sakadžić S, Saver JL, Scheer FAJL, Selim M, Tiedt S, Zhang F, Buchan AM. Stroke. 2021 May 4:STROKEAHA120031742. doi: 10.1161/STROKEAHA.120.031742.


Global Incidence of Neurological Manifestations Among Patients Hospitalized With COVID-19-A Report for the GCS-NeuroCOVID Consortium and the ENERGY Consortium.
Chou SH, Beghi E, Helbok R, Moro E, Sampson J, Altamirano V, Mainali S, Bassetti C, Suarez JI, McNett M; GCS-NeuroCOVID Consortium and ENERGY Consortium. JAMA Netw Open. 2021 May 3;4(5):e2112131. doi: 10.1001/jamanetworkopen.2021.12131.


Editorial: Epidemiology of Atypical Demyelinating Diseases.
Rotstein D, Kim SH, Hacohen Y, Levy M. Front Neurol. 2021 May 3;12:662353. doi: 10.3389/fneur.2021.662353. eCollection 2021.


Artificial Intelligence in Clinical Neurosurgery: More than Machinery.
Tewarie IA, Hulsbergen AFC, Gormley WB, Peul WC, Broekman MLD. World Neurosurg. 2021 May;149:302-303. doi: 10.1016/j.wneu.2021.02.057.


Aneurysmal Subarachnoid Hemorrhage.
Chung DY, Abdalkader M, Nguyen TN. Neurol Clin. 2021 May;39(2):419-442. doi: 10.1016/j.ncl.2021.02.006.


A Shortage of Neurologists We Must Act Now: A Report From the AAN 2019 Transforming Leaders Program.
Majersik JJ, Ahmed A, Chen IA, Shill H, Hanes GP, Pelak VS, Hopp JL, Omuro A, Kluger B, Leslie-Mazwi T. Neurology. 2021 Apr 30:10.1212/WNL.0000000000012111. doi: 10.1212/WNL.0000000000012111.


#RadialFirst and #RadialForNeuro: A descriptive analysis of Twitter conversations regarding transradial access.
Robertson FC, Linzey JR, Alotaibi NM, Regenhardt RW, Harker P, Vranic J, Dmytriw AA, Koch MJ, Stapleton CJ, Leslie-Mazwi TM, Patel AB. Neuroradiol J. 2021 Apr 30:19714009211012363. doi: 10.1177/19714009211012363.


Local and Distant responses to single pulse electrical stimulation reflect different forms of connectivity.
Crocker B, Ostrowski L, Williams ZM, Dougherty DD, Eskandar EN, Widge AS, Chu CJ, Cash SS, Paulk AC. Neuroimage. 2021 Apr 30:118094. doi: 10.1016/j.neuroimage.2021.118094.


Correction to: Sleep Neurology's Toolkit at the Crossroads: Challenges and Opportunities in Neurotherapeutics Lost and Found in Translation.
St Louis EK, Videnovic A. Neurotherapeutics. 2021 Apr 30. doi: 10.1007/s13311-021-01059-w.


ED-DEL: Development of a change package and toolkit for delirium in the emergency department.
Kennedy M, Webb M, Gartaganis S, Hwang U, Biese K, Stuck A, Lesser A, Hshieh T, Inouye SK. J Am Coll Emerg Physicians Open. 2021 Apr 29;2(2):e12421. doi: 10.1002/emp2.12421. eCollection


Generalized periodic discharges with triphasic morphology: to treat or not to treat?
Nascimento FA, Chen PM, Cohen J, Westover BM. Epileptic Disord. 2021 Apr 29. doi: 10.1684/epd.2021.1272


Novel botanical therapeutic NB-02 effectively treats Alzheimer's neuropathophysiology in an APP/PS1 mouse model.
Lee YF, Lariviere L, Russ AN, Choi SZ, Bacskai BJ, Kastanenka KV. eNeuro. 2021 Apr 28:ENEURO.0389-20.2021. doi: 10.1523/ENEURO.0389-20.2021.


Video Telehealth Occupational Therapy Services for Older Veterans: National Survey Study.
Gately ME, Tickle-Degnen L, Voydetich DJ, Ward N, Ladin K, Moo LR. JMIR Rehabil Assist Technol. 2021 Apr 27;8(2):e24299. doi: 10.2196/24299.


Evolving Phenotypes of non-hospitalized Patients that Indicate Long Covid.
Estiri H, Strasser ZH, Brat GA, Semenov YR, Patel CJ, Murphy SN. medRxiv. 2021 Apr 27:2021.04.25.21255923. doi: 10.1101/2021.04.25.21255923.


COVID-19 in a patient treated with eculizumab for aquaporin-4 neuromyelitis optica.
Cabal-Herrera AM, Mateen FJ. J Neurol. 2021 Apr 27:1-4. doi: 10.1007/s00415-021-10578-7. 


Teaching NeuroImages: Increasing SPECTations for Ictal SPECT in Epilepsy Surgical Evaluation.
Nascimento FA, Cochran RL, Chow DZ, Scott JA, Chu CJ. Neurology. 2021 Apr 26:10.1212/WNL.0000000000012097. doi: 10.1212/WNL.0000000000012097. 


CNS demyelination with TNFα inhibitor exposure: A retrospective cohort study.
Hutto SK, Rice DR, Mateen FJ. J Neuroimmunol. 2021 Apr 26;356:577587. doi: 10.1016/j.jneuroim.2021.577587.


Risk Factors With Neurotoxicity After Chimeric Antigen Receptor T-Cell Therapy-Reply.
Rubin DB, Jacobson C, Vaitkevicius H. JAMA Neurol. 2021 Apr 26. doi: 10.1001/jamaneurol.2021.0893.


Overlapping and dissociable brain activations for fluid intelligence and executive functions.
Santarnecchi E, Momi D, Mencarelli L, Plessow F, Saxena S, Rossi S, Rossi A, Mathan S, Pascual-Leone A. Cogn Affect Behav Neurosci. 2021 Apr 26. doi: 10.3758/s13415-021-00870-4.


Identifying Medicare beneficiaries with dementia.
Moura LMVR, Festa N, Price M, Volya M, Benson NM, Zafar S, Weiss M, Blacker D, Normand SL, Newhouse JP, Hsu J. J Am Geriatr Soc. 2021 Apr 26. doi: 10.1111/jgs.17183.


Unique actions of GABA arising from cytoplasmic chloride microdomains.
Rahmati N, Normoyle KP, Glykys J, Dzhala VI, Lillis KP, Kahle KT, Raiyyani R, Jacob T, Staley KJ. J Neurosci. 2021 Apr 26:JN-RM-3175-20. doi: 10.1523/JNEUROSCI.3175-20.2021.


Ischaemic stroke on anticoagulation therapy and early recurrence in acute cardioembolic stroke: the IAC study.
Yaghi S, Henninger N, Giles JA, Leon Guerrero C, Mistry E, Liberman AL, Asad D, Liu A, Nagy M, Kaushal A, Azher I, Mac Grory B, Fakhri H, Brown Espaillat K, Pasupuleti H, Martin H, Tan J, Veerasamy M, Esenwa C, Cheng N, Moncrieffe K, Moeini-Naghani I, Siddu M, Scher E, Trivedi T, Furie KL, Keyrouz SG, Nouh A, de Havenon A, Khan M, Smith EE, Gurol ME. J Neurol Neurosurg Psychiatry. 2021 Apr 26:jnnp-2021-326166. doi: 10.1136/jnnp-2021-326166.


CNS demyelination with TNFα inhibitor exposure: A retrospective cohort study
Hutto SK, Rice DR, Mateen FJ. J. Neuroim. 2021 Apr 25. doi: 10.1016/j.jneuroim.2021.577587


Synaptic proteins associated with cognitive performance and neuropathology in older humans revealed by multiplexed fractionated proteomics.
Carlyle BC, Kandigian SE, Kreuzer J, Das S, Trombetta BA, Kuo Y, Bennett DA, Schneider JA, Petyuk VA, Kitchen RR, Morris R, Nairn AC, Hyman BT, Haas W, Arnold SE. Neurobiol Aging. 2021 Apr 24;105:99-114. doi: 10.1016/j.neurobiolaging.2021.04.012.


Afferent and Efferent Neuro-Ophthalmic Complications of Coronavirus Disease 19
Tisdale AK, Dinkin M, Chwalisz BK. J Neuroophthalmol. 2021 Apr 24. doi: 10.1097/WNO.0000000000001276


Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial.
Dawson J, Liu CY, Francisco GE, Cramer SC, Wolf SL, Dixit A, Alexander J, Ali R, Brown BL, Feng W, DeMark L, Hochberg LR, Kautz SA, Majid A, O'Dell MW, Pierce D, Prudente CN, Redgrave J, Turner DL, Engineer ND, Kimberley TJ. Lancet. 2021 Apr 24;397(10284):1545-1553. doi: 10.1016/S0140-6736(21)00475-X.


Meningeal Multipotent Cells: A Hidden Target for CNS Repair?
Hayakawa K, Snyder EY, Lo EH. Neuromolecular Med. 2021 Apr 24. doi: 10.1007/s12017-021-08663-1.


Off-Label Promotion of Transcranial Magnetic Stimulation on Provider Websites.
Wexler A, Nagappan A, Kopyto D, Santarnecchi E, Pascual-Leone A. Brain Stimul. 2021 Apr 23:S1935-861X(21)00083-8. doi: 10.1016/j.brs.2021.04.013.


Covid-19: a call for mobilizing geriatric expertise.
O'Hanlon S, Dhesi J, Aronson L, Inouye SK. Eur Geriatr Med. 2021 Apr 23:1-4. doi: 10.1007/s41999-021-00500-9.


Contribution of Racial and Ethnic Differences in Cerebral Small Vessel Disease Subtype and Burden to Risk of Cerebral Hemorrhage Recurrence.
Castello JP, Pasi M, Abramson JR, Rodriguez-Torres A, Marini S, Demel S, Gilkerson L, Kubiszewski P, Charidimou A, Kourkoulis C, DiPucchio Z, Schwab K, Gurol ME, Viswanathan A, Anderson CD, Langefeld CD, Flaherty ML, Towfighi A, Greenberg SM, Woo D, Rosand J, Biffi A. Neurology. 2021 Apr 21:10.1212/WNL.0000000000011932. doi: 10.1212/WNL.0000000000011932.


Intraoperative thalamocortical tract monitoring via direct cortical recordings during craniotomy.
Simon MV, Curry WT, Jones PS, Cahill DP, Carter BS, Rapalino O, Malik AN, Nahed BV. Clin Neurophysiol. 2021 Apr 21;132(7):1416-1432. doi: 10.1016/j.clinph.2021.02.404.


Continuous Monitoring of Tau-Induced Neurotoxicity in Patient-Derived iPSC-Neurons.
Oakley DH, Klickstein N, Commins C, Chung M, Dujardin S, Bennett RE, Hyman BT, Frosch MP. J Neurosci. 2021 Apr 20:JN-RM-2590-20. doi: 10.1523/JNEUROSCI.2590-20.2021.


Restrictive diet in a patient with irritable bowel syndrome leading to Wernicke encephalopathy.
Wang Q, Charmchi Z, George IC. BMC Gastroenterol. 2021 Apr 20;21(1):179. doi: 10.1186/s12876-021-01758-w.


To reduce the risk of dementia focus on the patient.
Pascual-Leone A. Ann Neurol. 2021 Apr 18. doi: 10.1002/ana.26086.  


A Novel Method to Measure Venular Perivascular Spaces in Patients with MS on 7T MRI.
George IC, Arrighi-Allisan A, Delman BN, Balchandani P, Horng S, Feldman R. AJNR Am J Neuroradiol. 2021 Apr 15. doi: 10.3174/ajnr.A7144.


Cognitive Demands Influence Upper Extremity Motor Performance During Recovery From Acute Stroke.
Lin DJ, Erler KS, Snider SB, Bonkhoff AK, DiCarlo JA, Lam N, Ranford J, Parlman K, Cohen A, Freeburn J, Finklestein SP, Schwamm LH, Hochberg LR, Cramer SC. Neurology. 2021 Apr 15:10.1212/WNL.0000000000011992. doi: 10.1212/WNL.0000000000011992. 


Ibudilast (MN-166) In Amyotrophic Lateral Sclerosis - an Open Label, Safety and Pharmacodynamic Trial
Babu S, Hightower BG, Chan J,  Zürcher NR,  Kivisäkk P, Tseng CJ, Sanders DL, Robichaud A,  Banno H, Evora A,  Ashokkumar A,  Pothier L,  Paganoni S,  Chew S,  Dojillo J,  Matsuda K,  Gudesblatt M, Berry JD,  Cudkowicz ME,  Hooker JM, Atassi N. NeuroImage: Clinical. 2021 April 15. doi: 10.1016/j.nicl.2021.102672


Brain insulin signaling and cerebrovascular disease in human postmortem brain.
Arvanitakis Z, Capuano AW, Wang HY, Schneider JA, Kapasi A, Bennett DA, Ahima RS, Arnold SE. Acta Neuropathol Commun. 2021 Apr 15;9(1):71. doi: 10.1186/s40478-021-01176-9.


Spreading depression as an innate antiseizure mechanism.
Tamim I, Chung DY, de Morais AL, Loonen ICM, Qin T, Misra A, Schlunk F, Endres M, Schiff SJ, Ayata C. Nat Commun. 2021 Apr 13;12(1):2206. doi: 10.1038/s41467-021-22464-x.


Confirmed disability progression provides limited predictive information regarding future disease progression in multiple sclerosis.
Healy BC, Glanz BI, Swallow E, Signorovitch J, Hagan K, Silva D, Pelletier C, Chitnis T, Weiner H. Mult Scler J Exp Transl Clin. 2021 Apr 11;7(2):2055217321999070. doi: 10.1177/2055217321999070.


Algorithm for automatic detection of self-similarity and prediction of residual central respiratory events during continuous positive airway pressure.
Oppersma E, Ganglberger W, Sun H, Thomas RJ, Westover MB. Sleep. 2021 Apr 9;44(4):zsaa215. doi: 10.1093/sleep/zsaa215.


Evidence-Based Medicine Training in US-based Physiatry Residency Programs.
Annaswamy TM, Rizzo JR, Schnappinger A, Morgenroth DC, Engkasan JP, Ilieva E, Arnold WD, Boninger M, Bean AC, Cirstea CM, Dicianno BE, Fredericson M, Jayabalan P, Raghavan P, Sawaki L, Suri P, Suskauer SJ, Wang QM, Hosseini M, Case C, Whyte J, Paganoni S. Am J Phys Med Rehabil. 2021 Apr 8. doi: 10.1097/PHM.0000000000001752.


A simple method for implanting free-floating microdevices into the nervous tissue.
Khalifa A, Eisape A, Coughlin B, Cash SS. J Neural Eng. 2021 Apr 7. doi: 10.1088/1741-2552/abf590. 


Prolonged Intubation in Patients With Prior Cerebrovascular Disease and COVID-19.
Mukerji SS, Das S, Alabsi H, Brenner LN, Jain A, Magdamo C, Collens SI, Ye E, Keller K, Boutros CL, Leone MJ, Newhouse A, Foy B, Li MD, Lang M, Anahtar MN, Shao YP, Ge W, Sun H, Triant VA, Kalpathy-Cramer J, Higgins J, Rosand J, Robbins GK, Westover MB. Front Neurol. 2021 Apr 9;12:642912. doi: 10.3389/fneur.2021.642912.


Sleep Neurology's Toolkit at the Crossroads: Challenges and Opportunities in Neurotherapeutics Lost and Found in Translation.
Louis EKS, Videnovic A. Neurotherapeutics. 2021 Apr 5:1-5. doi: 10.1007/s13311-021-01032-7.


Connecting TDP-43 Pathology with Neuropathy.
Klim JR, Pintacuda G, Nash LA, Guerra San Juan I, Eggan K. Trends Neurosci. 2021 Apr 5:S0166-2236(21)00040-0. doi: 10.1016/j.tins.2021.02.008.


MCOLN1 gene therapy corrects neurologic dysfunction in the mouse model of mucolipidosis IV.
De Rosa S, Salani M, Smith S, Sangster M, Miller-Browne V, Wassmer S, Xiao R, Vandenberghe L, Slaugenhaupt S, Misko A, Grishchuk Y. Hum Mol Genet. 2021 Apr 5:ddab093. doi: 10.1093/hmg/ddab093.


Identification of Personalized Transcranial Magnetic Stimulation Targets Based on Subgenual Cingulate Connectivity: An Independent Replication.
Siddiqi SH, Weigand A, Pascual-Leone A, Fox MD. Biol Psychiatry. 2021 Apr 2:S0006-3223(21)00119-0. doi: 10.1016/j.biopsych.2021.02.015. 


Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.
Prokopenko D, Morgan SL, Mullin K, Hofmann O, Chapman B, Kirchner R; Alzheimer's Disease Neuroimaging Initiative (ADNI), Amberkar S, Wohlers I, Lange C, Hide W, Bertram L, Tanzi RE. Alzheimers Dement. 2021 Apr 2. doi: 10.1002/alz.12319.


Stress, resilience, and coping strategies in a sample of community-dwelling older adults during COVID-19.
Vannini P, Gagliardi GP, Kuppe M, Dossett ML, Donovan NJ, Gatchel JR, Quiroz YT, Premnath PY, Amariglio R, Sperling RA, Marshall GA. J Psychiatr Res. 2021 Apr 2;138:176-185. doi: 10.1016/j.jpsychires.2021.03.050.


A high-content platform for physiological profiling and unbiased classification of individual neurons.
DuBreuil DM, Chiang BM, Zhu K, Lai X, Flynn P, Sapir Y, Wainger BJ. Cell Rep Methods. 2021 May 24;1(1):100004. doi: 10.1016/j.crmeth.2021.100004.


Editorial: Understanding factors that, beyond plaques and tangles, contribute to the heterogeneity of Alzheimer disease and implications for the development of biomarkers and design of interventions.
Gomez-Isla T. Curr Opin Neurol. 2021 Apr 1;34(2):226-227. doi: 10.1097/WCO.0000000000000915.


Arm Motor Recovery After Ischemic Stroke: A Focus on Clinically Distinct Trajectory Groups.
Kline DK, Lin DJ, Cloutier A, Sloane K, Parlman K, Ranford J, Picard-Fraser M, Fox AB, Hochberg LR, Kimberley TJ. J Neurol Phys Ther. 2021 Apr 1;45(2):70-78. doi: 10.1097/NPT.0000000000000350.


Emerging Consciousness at a Clinical Crossroads.
Young MJ, Edlow BL. AJOB Neurosci. 2021 Apr-Sep;12(2-3):148-150. doi: 10.1080/21507740.2021.1904032.


Regional Changes in Patterns of Stroke Presentation During the COVID-19 Pandemic.
Etherton MR, Zachrison KS, Yan Z, Sveikata L, Bretzner M, Estrada J, Viswanathan A, Singhal AB, Schwamm LH. Stroke. 2021 Apr;52(4):1398-1406. doi: 10.1161/STROKEAHA.120.031300.


Common Data Elements for COVID-19 Neuroimaging: A GCS-NeuroCOVID Proposal.
Edlow BL, Boly M, Chou SH, Fischer D, Kondziella D, Li LM, Mac Donald CL, McNett M, Newcombe VFJ, Stevens RD, Menon DK; GCS-NeuroCOVID. Neurocrit Care. 2021 Apr;34(2):365-370. doi: 10.1007/s12028-021-01192-6.


The use of hydrogel-delivered extracellular vesicles in recovery of motor function in stroke: a testable experimental hypothesis for clinical translation including behavioral and neuroimaging assessment approaches.
Tsintou M, Dalamagkas K, Moore TL, Rathi Y, Kubicki M, Rosene DL, Makris N. Neural Regen Res. 2021 Apr;16(4):605-613. doi: 10.4103/1673-5374.295269.


Cerebral microbleeds and prediction of intracranial haemorrhage.
Greenberg SM. Lancet Neurol. 2021 Apr;20(4):252-254. doi: 10.1016/S1474-4422(21)00065-X.


Associations Between Trauma, Sleep, and Cognitive Impairment Among Latino and Asian Older Adults.
Saadi A, Cruz-Gonzalez M, Hwang A, Cohen L, Alegria M. J Am Geriatr Soc. 2021 Apr;69(4):1019-1026. doi: 10.1111/jgs.16986.


Ultra-high field (7T) functional magnetic resonance imaging in amyotrophic lateral sclerosis: a pilot study.
Barry RL, Babu S, Anteraper SA, Triantafyllou C, Keil B, Rowe OE, Rangaprakash D, Paganoni S, Lawson R, Dheel C, Cernasov PM, Rosen BR, Ratai EM, Atassi N. Neuroimage Clin. 2021 Mar 30;30:102648. doi: 10.1016/j.nicl.2021.102648.


HIV Increases Sleep-based Brain Age Despite Antiretroviral Therapy.
Leone MJ, Sun H, Boutros CL, Liu L, Ye E, Sullivan L, Thomas RJ, Robbins GK, Mukerji SS, Westover MB. Sleep. 2021 Mar 30:zsab058. doi: 10.1093/sleep/zsab058.


Home Use of a Percutaneous Wireless Intracortical Brain-Computer Interface by Individuals With Tetraplegia.
Simeral JD, Hosman T, Saab J, Flesher SN, Vilela M, Franco B, Kelemen J, Brandman DM, Ciancibello JG, Rezaii PG, Eskandar EN, Rosler DM, Shenoy KV, Henderson JM, Nurmikko AV, Hochberg LR. IEEE Trans Biomed Eng. 2021 Mar 30;PP. doi: 10.1109/TBME.2021.3069119. 


Injustice in Health: Now Is the Time to Change the Story.
Ogedegbe G, Inouye SK. Ann Intern Med. 2021 Mar 30. doi: 10.7326/M21-1279. 


Intracranial foreign body granuloma mimicking brain tumor recurrence: a case series.
Winter SF, Forst DA, Oakley DH, Batchelor TT, Dietrich J. Oncologist. 2021 Mar 29. doi: 10.1002/onco.13766. 


Parkinson's Disease Causative Mutation in Vps35 Disturbs Tetherin Trafficking to Cell Surfaces and Facilitates Virus Spread.
Ding Y, Li Y, Chhetri G, Peng X, Wu J, Wang Z, Zhao B, Zhao W, Li X. Cells. 2021 Mar 28;10(4):746. doi: 10.3390/cells10040746. 


Parkinson's Disease Causative Mutation in Vps35 Disturbs Tetherin Trafficking to Cell Surfaces and Facilitates Virus Spread.
Ding Y, Li Y, Chhetri G, Peng X, Wu J, Wang Z, Zhao B, Zhao W, Li X. Cells. 2021 Mar 28;10(4):746. doi: 10.3390/cells10040746.


The neurology of IGG4-related disease.
Saitakis G, Chwalisz BK. J Neurol Sci. 2021 Mar 27:117420. doi: 10.1016/j.jns.2021.117420.


Cerebral amyloid angiopathy and related inflammatory disorders.
Chwalisz BK. J Neurol Sci. 2021 Mar 27:117425. doi: 10.1016/j.jns.2021.117425.

Re: Predictors and outcomes of hemorrhagic stroke in reversible cerebral vasoconstriction syndrome (Garg et al., Volume 421, 117312, February 15, 2021).
Singhal AB. J Neurol Sci. 2021 Mar 27:117427. doi: 10.1016/j.jns.2021.117427.


Expectations and blind spots for structural variation detection from long-read assemblies and short-read genome sequencing technologies.
Zhao X, Collins RL, Lee WP, Weber AM, Jun Y, Zhu Q, Weisburd B, Huang Y, Audano PA, Wang H, Walker M, Lowther C, Fu J; Human Genome Structural Variation Consortium, Gerstein MB, Devine SE, Marschall T, Korbel JO, Eichler EE, Chaisson MJP, Lee C, Mills RE, Brand H, Talkowski ME. Am J Hum Genet. 2021 Mar 26:S0002-9297(21)00098-7. doi: 10.1016/j.ajhg.2021.03.014.  


Patient reported outcomes in ALS: characteristics of the self-entry ALS Functional Rating Scale-revised and the Activities-specific Balance Confidence Scale.
Chew S, Burke KM, Collins E, Church R, Paganoni S, Nicholson K, Babu S, Scalia JB, De Marchi F, Ellrodt AL, Moura LMVR, Chan J, Berry JD. Amyotroph Lateral Scler Frontotemporal Degener. 2021 Mar 26:1-11. doi: 10.1080/21678421.2021.1900259.


Association of APOE Genotype With Heterogeneity of Cognitive Decline Rate in Alzheimer Disease.
Qian J, Betensky RA, Hyman BT, Serrano-Pozo A. Neurology. 2021 Mar 26:10.1212/WNL.0000000000011883. doi: 10.1212/WNL.0000000000011883. 


A Phase 2 Proof-of-Concept, Randomized, Placebo-Controlled Trial of CX-8998 in Essential Tremor.
Papapetropoulos S, Lee MS, Versavel S, Newbold E, Jinnah HA, Pahwa R, Lyons KE, Elble R, Ondo W, Zesiewicz T, Hedera P, Handforth A, Elder J, Versavel M. Mov Disord. 2021 Mar 25. doi: 10.1002/mds.28584.


Utilization of Advanced Imaging for Acute Ischemic Stroke: The Ongoing Quest for Optimized Stroke Systems of Care.
Turner AC, Zachrison KS. Circ Cardiovasc Qual Outcomes. 2021 Mar 24:CIRCOUTCOMES121007845. doi: 10.1161/CIRCOUTCOMES.121.007845.  


Interplay Between Endocrine Disruptors and Immunity: Implications for Diseases of Autoreactive Etiology.
Popescu M, Feldman TB, Chitnis T. Front Pharmacol. 2021 Mar 23;12:626107. doi: 10.3389/fphar.2021.626107. eCollection 2021.


Associations between memory loss and trauma in US asylum seekers: A retrospective review of medico-legal affidavits.
Saadi A, Hampton K, de Assis MV, Mishori R, Habbach H, Haar RJ. PLoS One. 2021 Mar 23;16(3):e0247033. doi: 10.1371/journal.pone.0247033. eCollection 2021.


Microscale Physiological Events on the Human Cortical Surface.
Paulk AC, Yang JC, Cleary DR, Soper DJ, Halgren M, O'Donnell AR, Lee SH, Ganji M, Ro YG, Oh H, Hossain L, Lee J, Tchoe Y, Rogers N, Kiliç K, Ryu SB, Lee SW, Hermiz J, Gilja V, Ulbert I, Fabó D, Thesen T, Doyle WK, Devinsky O, Madsen JR, Schomer DL, Eskandar EN, Lee JW, Maus D, Devor A, Fried SI, Jones PS, Nahed BV, Ben-Haim S, Bick SK, Richardson RM, Raslan AM, Siler DA, Cahill DP, Williams ZM, Cosgrove GR, Dayeh SA, Cash SS. Cereb Cortex. 2021 Mar 22:bhab040. doi: 10.1093/cercor/bhab040.


Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via splice redirection.
Roy JCL, Vitalo A, Andrew MA, Mota-Silva E, Kovalenko M, Burch Z, Nhu AM, Cohen PE, Grabczyk E, Wheeler VC, Mouro Pinto R. Nucleic Acids Res. 2021 Mar 22:gkab152. doi: 10.1093/nar/gkab152.   


Impairment of visual cortical plasticity by amyloid-beta species.
William CM, Stern MA, Pei X, Saqran L, Ramani M, Frosch MP, Hyman BT. Neurobiol Dis. 2021 Mar 22;154:105344. doi: 10.1016/j.nbd.2021.105344.  


Obesity is associated with the Optic Neuritis severity in Male patients with Multiple Sclerosis.
Chu DT, Rosso M, Gonzalez CT, Saxena S, Healy BC, Weiner HL, Chitnis T. Mult Scler Relat Disord. 2021 Mar 21;51:102910. doi: 10.1016/j.msard.2021.102910.


Disposition of Proteins and Lipids in Synaptic Membrane Compartments Is Altered in Q175/Q7 Huntington's Disease Mouse Striatum.
Iuliano M, Seeley C, Sapp E, Jones EL, Martin C, Li X, DiFiglia M, Kegel-Gleason KB. Front Synaptic Neurosci. 2021 Mar 18;13:618391. doi: 10.3389/fnsyn.2021.618391.


Low-field portable brain MRI in CNS demyelinating disease.
Mateen FJ, Cooley CZ, Stockmann JP, Rice DR, Vogel AC, Wald LL. Mult Scler Relat Disord. 2021 Mar 18;51:102903. doi: 10.1016/j.msard.2021.102903.


Association of CSF Alzheimer's disease biomarkers with postoperative delirium in older adults.
Fong TG, Vasunilashorn SM, Gou Y, Libermann TA, Dillon S, Schmitt E, Arnold SE, Kivisäkk P, Carlyle B, Oh ES, Vlassakov K, Kunze L, Hshieh T, Jones RN, Marcantonio ER, Inouye SK; RISE Study Group. Alzheimers Dement (N Y). 2021 Mar 17;7(1):e12125. doi: 10.1002/trc2.12125. eCollection 2021.  


Cerebral microbleeds and prediction of intracranial haemorrhage.
Greenberg SM. Lancet Neurol. 2021 Apr;20(4):252-254. doi: 10.1016/S1474-4422(21)00065-X. Epub 2021 Mar 17. 


Quantitative Methods for the Detection of Tau Seeding Activity in Human Biofluids.
Lathuiliere A, Hyman BT. Front Neurosci. 2021 Mar 19;15:654176. doi: 10.3389/fnins.2021.654176. eCollection 2021.


Brain-Computer Interfaces in Neurorecovery and Neurorehabilitation.
Young MJ, Lin DJ, Hochberg LR. Semin Neurol. 2021 Mar 19. doi: 10.1055/s-0041-1725137. 


Persistent repression of tau in the brain using engineered zinc finger protein transcription factors.
Wegmann S, DeVos SL, Zeitler B, Marlen K, Bennett RE, Perez-Rando M, MacKenzie D, Yu Q, Commins C, Bannon RN, Corjuc BT, Chase A, Diez L, Nguyen HB, Hinkley S, Zhang L, Goodwin A, Ledeboer A, Lam S, Ankoudinova I, Tran H, Scarlott N, Amora R, Surosky R, Miller JC, Robbins AB, Rebar EJ, Urnov FD, Holmes MC, Pooler AM, Riley B, Zhang HS, Hyman BT. Sci Adv. 2021 Mar 19;7(12):eabe1611. doi: 10.1126/sciadv.abe1611.  


High-throughput phenotyping with temporal sequences.
Estiri H, Strasser ZH, Murphy SN. J Am Med Inform Assoc. 2021 Mar 18;28(4):772-781. doi: 10.1093/jamia/ocaa288.


Amyloid PET Imaging in Self-Identified Non-Hispanic Black Participants of the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) Study.
Deters KD, Napolioni V, Sperling RA, Greicius MD, Mayeux R, Hohman T, Mormino EC. Neurology. 2021 Mar 16;96(11):e1491-e1500. doi: 10.1212/WNL.0000000000011599.


Contextual MEG and EEG Source Estimates Using Spatiotemporal LSTM Networks.
Dinh C, Samuelsson JG, Hunold A, Hämäläinen MS, Khan S. Front Neurosci. 2021 Mar 9;15:552666. doi: 10.3389/fnins.2021.552666. eCollection 2021.


Neurological complications of cancer immunotherapy (CAR T cells).
Rubin DB, Vaitkevicius H. J Neurol Sci. 2021 Mar 18:117405. doi: 10.1016/j.jns.2021.117405


Functional dystonia: A case-control study and risk prediction algorithm.
Stephen CD, Perez DL, Chibnik LB, Sharma N. Ann Clin Transl Neurol. 2021 Mar 16. doi: 10.1002/acn3.51307.    


The Importance of Delirium and Delirium Prevention in Older Adults During Lockdowns.
Inouye SK. JAMA. 2021 Mar 15. doi: 10.1001/jama.2021.2211.


Degeneration Versus Development: Hunting-Out the D-Unit of Huntington's Disease.
Lu S, Lu B. Neurosci Bull. 2021 Mar 15.


Autoimmune encephalitis: new hammers in the toolbox.
Linnoila J. J Neurol Neurosurg Psychiatry. 2021 Mar 15:jnnp-2021-326096. doi: 10.1136/jnnp-2021-326096.


Teaching Video NeuroImages: Shedding Light on Sunflower Syndrome.
Nascimento FA, Thiele EA. Neurology. 2021 Mar 15:10.1212/WNL.0000000000011776. doi: 10.1212/WNL.0000000000011776.  


Closed-Eye Visual Hallucinations Associated With Clarithromycin.
Young MJ, Caplan RA, Connolly I, Matiello M, Mateen FJ. J Neuropsychiatry Clin Neurosci. 2021 Mar 12:appineuropsych20100253. doi: 10.1176/appi.neuropsych.20100253.


Children with autism spectrum disorder show altered functional connectivity and abnormal maturation trajectories in response to inverted faces.
Mamashli F, Kozhemiako N, Khan S, Nunes AS, McGuiggan NM, Losh A, Joseph RM, Ahveninen J, Doesburg SM, Hämäläinen MS, Kenet T. Autism Res. 2021 Mar 11. doi: 10.1002/aur.2497. 


IGF2R circular RNA hsa_circ_0131235 expression in the middle temporal cortex is associated with AD pathology.
Bigarré IM, Trombetta BA, Guo YJ, Arnold SE, Carlyle BC. Brain Behav. 2021 Mar 11:e02048. doi: 10.1002/brb3.2048.   


Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda.
Perez DL, Nicholson TR, Asadi-Pooya AA, Bègue I, Butler M, Carson AJ, David AS, Deeley Q, Diez I, Edwards MJ, Espay AJ, Gelauff JM, Hallett M, Horovitz SG, Jungilligens J, Kanaan RAA, Tijssen MAJ, Kozlowska K, LaFaver K, LaFrance WC Jr, Lidstone SC, Marapin RS, Maurer CW, Modirrousta M, Reinders AATS, Sojka P, Staab JP, Stone J, Szaflarski JP, Aybek S. Neuroimage Clin. 2021;30:102623. doi: 10.1016/j.nicl.2021.102623. Epub 2021 Mar 11.


Blood-Based Detection of BRAF V600E in Gliomas and Brain Tumor Metastasis.
Kang KM, Muralidharan K, Yekula A, Small JL, Rosh ZS, Jones PS, Carter BS, Balaj L. Cancers (Basel). 2021 Mar 11;13(6):1227. doi: 10.3390/cancers13061227.


High epileptiform discharge burden predicts delayed cerebral ischemia after subarachnoid hemorrhage.
Kim JA, Zheng WL, Elmer J, Jing J, Zafar SF, Ghanta M, Moura V Junior, Gilmore EJ, Hirsch LJ, Patel A, Rosenthal E, Westover MB. Clin Neurophysiol. 2021 Mar 10:S1388-2457(21)00063-8. doi: 10.1016/j.clinph.2021.01.022.


Behavioral and Neurodynamic Effects of Word Learning on Phonotactic Repair.
Gow DW, Schoenhaut A, Avcu E, Ahlfors SP. Front Psychol. 2021 Mar 10;12:590155. doi: 10.3389/fpsyg.2021.590155. eCollection 2021.


Atrophy in Distinct Corticolimbic Networks Subserving Socioaffective Behavior in Semantic Variant Primary Progressive Aphasia.
Eldaief MC, Perez DL, Quimby M, Hochberg D, Touroutoglou A, Feldman Barrett L, Dickerson BC. Dement Geriatr Cogn Disord. 2021 Mar 10:1-9. doi: 10.1159/000511341.  


Reply: Shouldn't Patients With Paradoxical Emboli and Thrombophilia Be Given Anticoagulant Agents?
Liu K, Song B, Palacios IF, Inglessis-Azuaje I, Lo EH, Xu Y, Buonanno FS, Ning M. JACC Cardiovasc Interv. 2021 Mar 8;14(5):583-584. doi: 10.1016/j.jcin.2021.01.002.


Affective symptoms and regional cerebral tau burden in early-stage Alzheimer's disease.
Tommasi NS, Gonzalez C, Briggs D, Properzi MJ, Gatchel JR, Marshall GA; Alzheimer’s Disease Neuroimaging Initiative**. Int J Geriatr Psychiatry. 2021 Mar 8. doi: 10.1002/gps.5530. 


Individualized prediction of COVID-19 adverse outcomes with MLHO.
Estiri H, Strasser ZH, Murphy SN. Sci Rep. 2021 Mar 5;11(1):5322. doi: 10.1038/s41598-021-84781-x.


In vivo brain imaging of mitochondrial Ca2+ in neurodegenerative diseases with multiphoton microscopy. Calvo-Rodriguez M, Kharitonova EK, Bacskai BJ. Biochim Biophys Acta Mol Cell Res. 2021 Mar 5:118998. doi: 10.1016/j.bbamcr.2021.118998.  


Hereditary Myelopathies.
Walker MA. Semin Neurol. 2021 Mar 4. doi: 10.1055/s-0041-1725153. 


Principles of Neural Repair and Their Application to Stroke Recovery Trials.
Lin DJ, Cramer SC. Semin Neurol. 2021 Mar 4. doi: 10.1055/s-0041-1725140. 


Xenopus models suggest convergence of gene signatures on neurogenesis in autism.
Brennand KJ, Talkowski ME. Neuron. 2021 Mar 3;109(5):743-745. doi: 10.1016/j.neuron.2021.02.017.


Decomposition of Reaching Movements Enables Detection and Measurement of Ataxia.
Oubre B, Daneault JF, Whritenour K, Khan NC, Stephen CD, Schmahmann JD, Lee SI, Gupta AS. Cerebellum. 2021 Mar 2. doi: 10.1007/s12311-021-01247-6.


Abnormal dynamic functional connectivity is linked to recovery after acute ischemic stroke.
Bonkhoff AK, Schirmer MD, Bretzner M, Etherton M, Donahue K, Tuozzo C, Nardin M, Giese AK, Wu O, D Calhoun V, Grefkes C, Rost NS. Hum Brain Mapp. 2021 Mar 2. doi: 10.1002/hbm.25366.


The Quest for Covert Consciousness: Bringing Neuroethics to the Bedside.
Young MJ, Edlow BL. Neurology. 2021 Mar 2:10.1212/WNL.0000000000011734. doi: 10.1212/WNL.0000000000011734.


High-Density EEG in Current Clinical Practice and Opportunities for the Future.
Stoyell SM, Wilmskoetter J, Dobrota MA, Chinappen DM, Bonilha L, Mintz M, Brinkmann BH, Herman ST, Peters JM, Vulliemoz S, Seeck M, Hämäläinen MS, Chu CJ. J Clin Neurophysiol. 2021 Mar 1;38(2):112-123. doi: 10.1097/WNP.0000000000000807. 


Refugee Mental Health-An Urgent Call for Research and Action.
Saadi A, Al-Rousan T, AlHeresh R. JAMA Netw Open. 2021 Mar 1;4(3):e212543. doi: 10.1001/jamanetworkopen.2021.2543.


Therapeutic Neuromodulation for Bipolar Disorder-The Case for Biomarker-Driven Treatment Development.
Camprodon JA. JAMA Netw Open. 2021 Mar 1;4(3):e211055. doi: 10.1001/jamanetworkopen.2021.1055.


Clinical, radiological and genomic features and targeted therapy in BRAF V600E mutant adult glioblastoma.
Lim-Fat MJ, Song KW, Iorgulescu JB, Andersen BM, Forst DA, Jordan JT, Gerstner ER, Reardon DA, Wen PY, Arrillaga-Romany I. J Neurooncol. 2021 Mar 1. doi: 10.1007/s11060-021-03719-5. 


Holding Out Hope After Traumatic Brain Injury.
Kim JA, Sheth KN. JAMA Neurol. 2021 Mar 1. doi: 10.1001/jamaneurol.2020.5328. 


The (Extracellular) Matrix Reloaded: Imaging Matrix Metalloproteinase Activity.
Lillis KP. Epilepsy Curr. 2021 Jan 28;21(2):120-121. doi: 10.1177/1535759720988547. eCollection 2021 Mar-Apr.


Clinical and electrophysiological evaluation of myasthenic features in an alpha-dystroglycanopathy cohort (FKRP-predominant).
Gonzalez-Perez P, Smith C, Sebetka WL, Gedlinske A, Perlman S, Mathews KD. Neuromuscul Disord. 2020 Mar;30(3):213-218. doi: 10.1016/j.nmd.2020.01.002.


Stroke in Pregnancy: A Multidisciplinary Approach.
Camargo EC, Singhal AB. Obstet Gynecol Clin North Am. 2021 Mar;48(1):75-96. doi: 10.1016/j.ogc.2020.11.004. 


Neuro-ophthalmic Complications of Immune-Checkpoint Inhibitors.
Mukharesh L, Chwalisz BK. Semin Ophthalmol. 2021 Feb 27:1-9. doi: 10.1080/08820538.2021.1890796.  


Bright spotty lesions as an imaging marker for neuromyelitis optica spectrum disorder.
Salama S, Levy M. Mult Scler. 2021 Feb 26:1352458521994259. doi: 10.1177/1352458521994259.


Teleneurology-Enabled Determination of Death by Neurologic Criteria After Cardiac Arrest or Severe Neurologic Injury.
Matiello M, Turner AC, Estrada J, Whitney CM, Kitch BT, Lee PT, Girkar U, Palacios R, Singla P, Schwamm L. Neurology. 2021 Feb 26:10.1212/WNL.0000000000011751. doi: 10.1212/WNL.0000000000011751. 


The combined use of steroids and immune checkpoint inhibitors in brain metastasis patients: a systematic review and meta-analysis.
Jessurun CAC, Hulsbergen AFC, de Wit AE, Tewarie IA, Snijders TJ, Verhoeff J, Phillips J, Reardon DA, Mekary RA, Broekman MLD. Neuro Oncol. 2021 Feb 25:noab046. doi: 10.1093/neuonc/noab046. 


Hippocampal sharp wave ripples during invasive monitoring: A physiologic finding.
McLaren JR, Shi W, Misko AL, Emerton BC, Chu CJ. Clin Neurophysiol. 2021 Feb 24;132(5):1077-1079. doi: 10.1016/j.clinph.2021.02.003.


Machine and deep learning in MS research are just powerful statistics - No.
Healy BC. Mult Scler. 2021 Feb 24:1352458520978648. doi: 10.1177/1352458520978648.


One-Year Medicare Costs Associated With Delirium in Older Patients Undergoing Major Elective Surgery.
Gou RY, Hshieh TT, Marcantonio ER, Cooper Z, Jones RN, Travison TG, Fong TG, Abdeen A, Lange J, Earp B, Schmitt EM, Leslie DL, Inouye SK; SAGES Study Group. JAMA Surg. 2021 Feb 24. doi: 10.1001/jamasurg.2020.7260.


Understanding Sunflower syndrome: Results of an online questionnaire.
Barnett JR, Fleming BM, Doshi SP, Freedman J, Ambrosio NR, Geenen KR, Bruno PL, Thiele EA. Epilepsy Behav. 2021 Feb 24;117:107856. doi: 10.1016/j.yebeh.2021.107856.  


Association of Memory Impairment with Concomitant Tau Pathology in Patients with Cerebral Amyloid Angiopathy.
Schoemaker D, Charidimou A, Zanon Zotin MC, Raposo N, Johnson KA, Sanchez JS, Greenberg SM, Viswanathan A. Neurology. 2021 Feb 24:10.1212/WNL.0000000000011745. doi: 10.1212/WNL.0000000000011745. 


Neurologic Manifestations of the World Health Organization's List of Pandemic and Epidemic Diseases.
McEntire CRS, Song KW, McInnis RP, Rhee JY, Young M, Williams E, Wibecan LL, Nolan N, Nagy AM, Gluckstein J, Mukerji SS, Mateen FJ. Front Neurol. 2021 Feb 22;12:634827. doi: 10.3389/fneur.2021.634827.  


Neuropsychiatry, Palliative Care, and Culture: What Matters Beyond Diagnosis.
Chemali Z, Biffi A, Buch K, Song KW, Osman H. Prim Care Companion CNS Disord. 2021 Feb 24;23(2):20l02610. doi: 10.4088/PCC.20l02610. PMID: 34000122


Ptosis as Clinical Presentation in a Patient With Emery-Dreifuss Muscular Dystrophy Type 5.
Douglas KAA, Douglas VP, Gaier ED, Chwalisz BK. J Neuroophthalmol. 2021 Feb 19. doi: 10.1097/WNO.0000000000001187.


A high proportion of novel ACAN mutations and their prevalence in a large cohort of Chinese short stature children.
Lin L, Li M, Luo J, Li P, Zhou S, Yang Y, Chen K, Weng Y, Ge X, Mireguli M, Wei H, Yang H, Li G, Sun Y, Cui L, Zhang S, Chen J, Zeng G, Xu L, Luo X, Shen Y. J Clin Endocrinol Metab. 2021 Feb 19:dgab088. doi: 10.1210/clinem/dgab088.  


Serum NFL levels predict progression of motor impairment and reduction in putamen dopamine transporter binding ratios in de novo Parkinson's disease: An 8-year longitudinal study.
Ye R, Locascio JJ, Goodheart AE, Quan M, Zhang B, Gomperts SN. Parkinsonism Relat Disord. 2021 Feb 17;85:11-16. doi: 10.1016/j.parkreldis.2021.02.008.


Optical coherence tomography of arteriolar diameter and capillary perfusion during spreading depolarizations.
Anzabi M, Li B, Wang H, Kura S, Sakadžić S, Boas D, Østergaard L, Ayata C. J Cereb Blood Flow Metab. 2021 Feb 16:271678X21994013. doi: 10.1177/0271678X21994013.


Is the COVID-19 pandemic magnifying disparities in stroke treatment?
Regenhardt RW, Young MJ, Leslie-Mazwi TM. J Neurointerv Surg. 2021 Feb 16:neurintsurg-2021-017292. doi: 10.1136/neurintsurg-2021-017292.   


Regional Changes in Patterns of Stroke Presentation During the COVID-19 Pandemic.
Etherton MR, Zachrison KS, Yan Z, Sveikata L, Bretzner M, Estrada J, Viswanathan A, Singhal AB, Schwamm LH. Stroke. 2021 Feb 16:STROKEAHA120031300. doi: 10.1161/STROKEAHA.120.031300.


Association of Digital Clock Drawing with PET Amyloid and Tau Pathology in Normal Older Adults.
Rentz DM, Papp KV, Mayblyum DV, Sanchez JS, Klein H, Souillard-Mandar W, Sperling RA, Johnson KA. Neurology. 2021 Feb 15:10.1212/WNL.0000000000011697. doi: 10.1212/WNL.0000000000011697. 


Regional prefrontal cortical atrophy predicts specific cognitive-behavioral symptoms in ALS-FTD.
Ratti E, Domoto-Reilly K, Caso C, Murphy A, Brickhouse M, Hochberg D, Makris N, Cudkowicz ME, Dickerson BC. Brain Imaging Behav. 2021 Feb 15. doi: 10.1007/s11682-021-00456-1.


Machine learning identifies candidates for drug repurposing in Alzheimer's disease.
Rodriguez S, Hug C, Todorov P, Moret N, Boswell SA, Evans K, Zhou G, Johnson NT, Hyman BT, Sorger PK, Albers MW, Sokolov A. Nat Commun. 2021 Feb 15;12(1):1033. doi: 10.1038/s41467-021-21330-0. 


Workshop report. Circadian rhythm sleep-wake disorders: gaps and opportunities.
Duffy JF, Abbott SM, Burgess HJ, Crowley SJ, Emens JS, Epstein LJ, Gamble KL, Hasler BP, Kristo DA, Malkani RG, Rahman SA, Thomas SJ, Wyatt JK, Zee PC, Klerman EB. Sleep. 2021 Feb 14:zsaa281. doi: 10.1093/sleep/zsaa281.


Evaluation of Fluorinated Cromolyn Derivatives as Potential Therapeutics for Alzheimer's Disease.
Shoup TM, Griciuc A, Normandin MD, Quinti L, Walsh LV, Dhaynaut M, Moon SH, Guehl NJ, Brugarolas P, Elmaleh DR, Fakhri GE, Tanzi RE. J Alzheimers Dis. 2021 Feb 12. doi: 10.3233/JAD-201419.


A Virtual, Randomized, Control Trial of a Digital Therapeutic for Speech, Language, and Cognitive Intervention in Post-stroke Persons With Aphasia.
Braley M, Pierce JS, Saxena S, De Oliveira E, Taraboanta L, Anantha V, Lakhan SE, Kiran S. Front Neurol. 2021 Feb 12;12:626780. doi: 10.3389/fneur.2021.626780.


Comparison of Two Clinical Upper Motor Neuron Burden Rating Scales in ALS Using Quantitative Brain Imaging.
Makary MM, Weerasekara A, Rodham H, Hightower BG, Tseng CJ, Chan J, Chew S, Paganoni S, Ratai EM, Zürcher NR, Hooker JM, Atassi N, Babu S. ACS Chem Neurosci. 2021 Feb 12. doi: 10.1021/acschemneuro.0c00772.


18F-AV-1451 positron emission tomography in neuropathological substrates of corticobasal syndrome.
Goodheart AE, Locascio JJ, Samore WR, Collins JA, Brickhouse M, Schultz A, Touroutoglou A, Johnson KA, Frosch MP, Growdon JH, Dickerson BC, Gomperts SN. Brain. 2021 Feb 12;144(1):266-277. doi: 10.1093/brain/awaa383.  


Differential gene expression data from the human central nervous system across Alzheimer's disease, Lewy body diseases, and the amyotrophic lateral sclerosis and frontotemporal dementia spectrum.
Noori A, Mezlini AM, Hyman BT, Serrano-Pozo A, Das S. Data Brief. 2021 Feb 11;35:106863. doi: 10.1016/j.dib.2021.106863.


Amyloid PET imaging in self-identified non-Hispanic Blacks from the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) Study.
Deters K, Napolioni V, Sperling RA, Greicius MD, Mayeux R, Hohman T, Mormino EC. Neurology. 2021 Feb 10:10.1212/WNL.0000000000011599. doi: 10.1212/WNL.0000000000011599.


Validation of an Internationally Derived Patient Severity Phenotype to Support COVID-19 Analytics from Electronic Health Record Data.
Klann JG, Weber GM, Estiri H, Moal B, Avillach P, Hong C, Castro V, Maulhardt T, Tan ALM, Geva A, Beaulieu-Jones BK, Malovini A, South AM, Visweswaran S, Omenn GS, Ngiam KY, Mandl KD, Boeker M, Olson KL, Mowery DL, Morris M, Follett RW, Hanauer DA, Bellazzi R, Moore JH, Loh NW, Bell DS, Wagholikar KB, Chiovato L, Tibollo V, Rieg S, Li ALLJ, Jouhet V, Schriver E, Samayamuthu MJ, Xia Z, Hutch M, Luo Y; Consortium for Clinical Characterization of COVID-19 by EHR (4CE) (CONSORTIA AUTHOR), Kohane IS, Brat GA, Murphy SN. J Am Med Inform Assoc. 2021 Feb 10:ocab018. doi: 10.1093/jamia/ocab018. 


Implementation of high-cadence cycling for Parkinson's disease in the community setting: A pragmatic feasibility study.
McKee KE, Johnson RK, Chan J, Wills AM. Brain Behav. 2021 Feb 9:e02053. doi: 10.1002/brb3.2053.


Is MRI in the Angiographic Suite a New Frontier?
Lev MH, Leslie-Mazwi TM. Radiology. 2021 Feb 9:204563. doi: 10.1148/radiol.2021204563.  


Mind the translational gap: using iPS cell models to bridge from genetic discoveries to perturbed pathways and therapeutic targets.
Pintacuda G, Martín JM, Eggan KC. Mol Autism. 2021 Feb 8;12(1):10. doi: 10.1186/s13229-021-00417-x.  


Neuropsychiatric symptoms in a occipito-temporal infarction with remarkable long-term functional recovery.
Tanev KS, Federico LE, Sydnor VJ, Leveroni CL, Hassan K, Biffi A. Cortex. 2021 Feb 6;137:205-214. doi: 10.1016/j.cortex.2021.01.013.


Reimagining Stroke Rehabilitation and Recovery Across the Care Continuum: Results from a Design-Thinking Workshop to Identify Challenges and Propose Solutions.
DiCarlo JA, Gheihman G, Lin DJ; 2019 Northeast Cerebrovascular Consortium Conference Stroke Recovery Workshop Participants. Arch Phys Med Rehabil. 2021 Feb 5:S0003-9993(21)00142-8. doi: 10.1016/j.apmr.2021.01.074.


Predicting COVID-19 mortality with electronic medical records.
Estiri H, Strasser ZH, Klann JG, Naseri P, Wagholikar KB, Murphy SN. NPJ Digit Med. 2021 Feb 4;4(1):15. doi: 10.1038/s41746-021-00383-x.


Functional Dystonia: Differentiation From Primary Dystonia and Multidisciplinary Treatments.
Frucht L, Perez DL, Callahan J, MacLean J, Song PC, Sharma N, Stephen CD. Front Neurol. 2021 Feb 4;11:605262. doi: 10.3389/fneur.2020.605262. eCollection 2020.


CTA Protocols in a Telestroke Network Improve Efficiency for Both Spoke and Hub Hospitals.
Yu AT, Regenhardt RW, Whitney C, Schwamm LH, Patel AB, Stapleton CJ, Viswanathan A, Hirsch JA, Lev M, Leslie-Mazwi TM. AJNR Am J Neuroradiol. 2021 Feb 4. doi: 10.3174/ajnr.A6950.


The role of innate immune genes in Alzheimer's disease.
Griciuc A, Tanzi RE. Curr Opin Neurol. 2021 Feb 3. doi: 10.1097/WCO.0000000000000911. 


Lacunes, Microinfarcts and Vascular Dysfunction in Cerebral Amyloid Angiopathy.
Gokcal E, Horn MJ, van Veluw SJ, Frau-Pascual A, Das AS, Pasi M, Fotiadis P, Warren AD, Schwab K, Rosand J, Viswanathan A, Polimeni JR, Greenberg SM, Gurol ME. Neurology. 2021 Feb 3:10.1212/WNL.0000000000011631. doi: 10.1212/WNL.0000000000011631.


Challenges and Opportunities in Multimodal Monitoring and Data Analytics in Traumatic Brain Injury.
Foreman B, Lissak IA, Kamireddi N, Moberg D, Rosenthal ES. Curr Neurol Neurosci Rep. 2021 Feb 2;21(3):6. doi: 10.1007/s11910-021-01098-y.


Patterns of antidepressant therapy and clinical outcomes among ischaemic stroke survivors.
Etherton MR, Shah S, Haolin X, Xian Y, Maisch L, Hannah D, Lindholm B, Lytle B, Thomas L, Smith EE, Fonarow GC, Schwamm LH, Bhatt DL, Hernandez AF, O'Brien EC. Stroke Vasc Neurol. 2021 Feb 1:svn-2020-000691. doi: 10.1136/svn-2020-000691


Clinical Characteristics and Outcomes Associated With Oral Anticoagulant Use Among Patients Hospitalized With Intracerebral Hemorrhage.
Xian Y, Zhang S, Inohara T, Grau-Sepulveda M, Matsouaka RA, Peterson ED, Piccini JP, Smith EE, Sheth KN, Bhatt DL, Fonarow GC, Schwamm LH. JAMA Netw Open. 2021 Feb 1;4(2):e2037438. doi: 10.1001/jamanetworkopen.2020.37438.


Robust Stability of Melatonin Circadian Phase, Sleep Metrics, and Chronotype Across Months in Young Adults Living in Real-World Settings.
McHill AW, Sano A, Hilditch CJ, Barger LK, Czeisler CA, Picard R, Klerman EB. J Pineal Res. 2021 Feb 1:e12720. doi: 10.1111/jpi.12720.


Language preference does not influence stroke patients' symptom recognition or emergency care time metrics.
Zachrison KS, Natsui S, Luan Erfe BM, Mejia NI, Schwamm LH. Am J Emerg Med. 2021 Feb;40:177-180. doi: 10.1016/j.ajem.2020.10.064.


The best matrix for the brain: advances in secondary CNS lymphoma.Dietrich J. Lancet Haematol. 2021 Feb;8(2):e96-e97. doi: 10.1016/S2352-3026(20)30431-2.  


Inequities in neurology amplified by the COVID-19 pandemic.
Nolen L, Mejia NI. Nat Rev Neurol. 2021 Feb;17(2):67-68. doi: 10.1038/s41582-020-00452-x. 


Telemedicine Can Support Measurable and High-Quality Epilepsy Care During the COVID-19 Pandemic.
Moura LMVR, Donahue MA, Smith JR, Dass D, Sanches PR, Ayub N, McGraw C, Zafar SF, Cash SS, Hoch DB. Am J Med Qual. 2021 Jan-Feb 01;36(1):5-16. doi: 10.1097/01.JMQ.0000733444.71245.6c.


Author Correction: Evaluating drug targets through human loss-of-function genetic variation.
Minikel EV, Karczewski KJ, Martin HC, Cummings BB, Whiffin N, Rhodes D, Alföldi J, Trembath RC, van Heel DA, Daly MJ; Genome Aggregation Database Production Team; Genome Aggregation Database Consortium, Schreiber SL, MacArthur DG. Nature. 2021 Feb;590(7846):E56. doi: 10.1038/s41586-020-03177-5.


Author Correction: A structural variation reference for medical and population genetics.
Collins RL, Brand H, Karczewski KJ, Zhao X, Alföldi J, Francioli LC, Khera AV, Lowther C, Gauthier LD, Wang H, Watts NA, Solomonson M, O'Donnell-Luria A, Baumann A, Munshi R, Walker M, Whelan CW, Huang Y, Brookings T, Sharpe T, Stone MR, Valkanas E, Fu J, Tiao G, Laricchia KM, Ruano-Rubio V, Stevens C, Gupta N, Cusick C, Margolin L; Genome Aggregation Database Production Team; Genome Aggregation Database Consortium, Taylor KD, Lin HJ, Rich SS, Post WS, Chen YI, Rotter JI, Nusbaum C, Philippakis A, Lander E, Gabriel S, Neale BM, Kathiresan S, Daly MJ, Banks E, MacArthur DG, Talkowski ME. Nature. 2021 Feb;590(7846):E55. doi: 10.1038/s41586-020-03176-6.


Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.
Dujardin S, Commins C, Lathuiliere A, Beerepoot P, Fernandes AR, Kamath TV, De Los Santos MB, Klickstein N, Corjuc DL, Corjuc BT, Dooley PM, Viode A, Oakley DH, Moore BD, Mullin K, Jean-Gilles D, Clark R, Atchison K, Moore R, Chibnik LB, Tanzi RE, Frosch MP, Serrano-Pozo A, Elwood F, Steen JA, Kennedy ME, Hyman BT. Nat Med. 2021 Jan 29. doi: 10.1038/s41591-021-01251-7.


Uridine-responsive epileptic encephalopathy due to inherited variants in CAD: A Tale of Two Siblings.
McGraw CM, Mahida S, Jayakar P, Koh HY, Taylor A, Resnick T, Rodan L, Schwartz MA, Ejaz A, Sankaran VG, Berry G, Poduri A. Ann Clin Transl Neurol. 2021 Jan 26. doi: 10.1002/acn3.51272.  


Case Report: Deep Brain Stimulation to the Ventral Internal Capsule/Ventral Striatum Induces Repeated Transient Episodes of Voltage-Dependent Tourette-Like Behaviors.
Camprodon JA, Chou T, Testo AA, Deckersbach T, Scharf JM, Dougherty DD. Front Hum Neurosci. 2021 Jan 25;14:590379. doi: 10.3389/fnhum.2020.590379.


Serum neurofilament levels and patient-reported outcomes in multiple sclerosis.
Galetta K, Deshpande C, Healy BC, Glanz B, Ziehn M, Saxena S, Paul A, Saleh F, Collins M, Gaitan-Walsh P, Castro-Mendoza P, Weiner HL, Chitnis T. Ann Clin Transl Neurol. 2021 Jan 25. doi: 10.1002/acn3.51305. 


A transdiagnostic and biopsychosocial-informed perspective across functional seizures and functional movement disorder.
Saxena A, Perez DL. Epilepsy Behav. 2021 Jan 25:107749. doi: 10.1016/j.yebeh.2020.107749.


Unmasking Covert Language Processing in the Intensive Care Unit with EEG.
Edlow BL, Naccache L. Ann Neurol. 2021 Jan 25. doi: 10.1002/ana.26030.


Child Neurology: Intractable Epilepsy and Transient Deficits in a Patient with a History of HSV Encephalitis.
Manzano GS, Danish HH, Chu CJ, Kimchi EY. Neurology. 2021 Jan 25:10.1212/WNL.0000000000011606. doi: 10.1212/WNL.0000000000011606. 


Electroencephalography, Hospital Complications, and Longitudinal Outcomes After Subarachnoid Hemorrhage.
Lissak IA, Locascio JJ, Zafar SF, Schleicher RL, Patel AB, Leslie-Mazwi T, Stapleton CJ, Koch MJ, Kim JA, Anderson K, Rosand J, Westover MB, Kimberly WT, Rosenthal ES. Neurocrit Care. 2021 Jan 22. doi: 10.1007/s12028-020-01177-x. 


MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols.
Wilcock D, Jicha G, Blacker D, Albert MS, D'Orazio LM, Elahi FM, Fornage M, Hinman JD, Knoefel J, Kramer J, Kryscio RJ, Lamar M, Moghekar A, Prestopnik J, Ringman JM, Rosenberg G, Sagare A, Satizabal CL, Schneider J, Seshadri S, Sur S, Tracy RP, Yasar S, Williams V, Singh H, Mazina L, Helmer KG, Corriveau RA, Schwab K, Kivisäkk P, Greenberg SM; MarkVCID Consortium. Alzheimers Dement. 2021 Jan 21. doi: 10.1002/alz.12215. 


Intranasal delivery of experimental compounds in orthotopic brain tumor mouse models.
Eyme KM, Carvalho L, Badr CE. STAR Protoc. 2021 Jan 21;2(1):100290. doi: 10.1016/j.xpro.2020.100290. eCollection 2021 Mar 19.


MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols.
Lu H, Kashani AH, Arfanakis K, Caprihan A, DeCarli C, Gold BT, Li Y, Maillard P, Satizabal CL, Stables L, Wang DJJ, Corriveau RA, Singh H, Smith EE, Fischl B, van der Kouwe A, Schwab K, Helmer KG, Greenberg SM; MarkVCID Consortium. Alzheimers Dement. 2021 Jan 21. doi: 10.1002/alz.12216. 


MRI Lesion State Modulates the Relationship Between Serum Neurofilament Light and Age in Multiple Sclerosis.
Rosso M, Healy BC, Saxena S, Paul A, Bjornevik K, Kuhle J, Benkert P, Leppert D, Guttmann C, Bakshi R, Weiner HL, Chitnis T. J Neuroimaging. 2021 Jan 21. doi: 10.1111/jon.12826.


Should neurosurgeons continue to work in the absence of personal protective equipment during the COVID-19 era?
Eijkholt M, Hulsbergen A, Muskens I, Mathiesen TI, Bolger C, Feldman Z, Kitchen N, Samprón N, Sandvik U, Tisell M, Broekman M. Acta Neurochir (Wien). 2021 Jan 20. doi: 10.1007/s00701-021-04703-8


The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography.
Sanchez JS, Becker JA, Jacobs HIL, Hanseeuw BJ, Jiang S, Schultz AP, Properzi MJ, Katz SR, Beiser A, Satizabal CL, O'Donnell A, DeCarli C, Killiany R, El Fakhri G, Normandin MD, Gómez-Isla T, Quiroz YT, Rentz DM, Sperling RA, Seshadri S, Augustinack J, Price JC, Johnson KA. Sci Transl Med. 2021 Jan 20;13(577):eabc0655. doi: 10.1126/scitranslmed.abc0655.


Breakdowns in Informativeness of Naturalistic Speech Production in Primary Progressive Aphasia.
Gallée J, Cordella C, Fedorenko E, Hochberg D, Touroutoglou A, Quimby M, Dickerson BC. Brain Sci. 2021 Jan 20;11(2):E130. doi: 10.3390/brainsci11020130.


Machine Learning-Driven Metabolomic Evaluation of Cerebrospinal Fluid: Insights Into Poor Outcomes After Aneurysmal Subarachnoid Hemorrhage.
Koch M, Acharjee A, Ament Z, Schleicher R, Bevers M, Stapleton C, Patel A, Kimberly WT. Neurosurgery. 2021 Jan 19:nyaa557. doi: 10.1093/neuros/nyaa557. 


Fibroblasts from idiopathic Parkinson's disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2.
Thomas R, Moloney EB, Macbain ZK, Hallett PJ, Isacson O. Mol Brain. 2021 Jan 19;14(1):16. doi: 10.1186/s13041-020-00712-3.  


Circadian and Sleep Dysfunctions in Neurodegenerative Disorders-An Update.
Fifel K, Videnovic A. Front Neurosci. 2021 Jan 18;14:627330. doi: 10.3389/fnins.2020.627330.


Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19.
Conklin J, Frosch MP, Mukerji SS, Rapalino O, Maher MD, Schaefer PW, Lev MH, Gonzalez RG, Das S, Champion SN, Magdamo C, Sen P, Harrold GK, Alabsi H, Normandin E, Shaw B, Lemieux JE, Sabeti PC, Branda JA, Brown EN, Westover MB, Huang SY, Edlow BL. J Neurol Sci. 2021 Jan 15;421:117308. doi: 10.1016/j.jns.2021.117308.


Focal sleep spindle deficits reveal focal thalamocortical dysfunction and predict cognitive deficits in childhood epilepsy with centrotemporal spikes.
Kramer MA, Stoyell SM, Chinappen D, Ostrowski LM, Spencer ER, Morgan AK, Emerton BC, Jing J, Westover MB, Eden UT, Stickgold R, Manoach DS, Chu CJ. J Neurosci. 2021 Jan 14:JN-RM-2009-20. doi: 10.1523/JNEUROSCI.2009-20.2020.  


Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation.
Amaral AC, Perez-Nievas BG, Siao Tick Chong M, Gonzalez-Martinez A, Argente-Escrig H, Rubio-Guerra S, Commins C, Muftu S, Eftekharzadeh B, Hudry E, Fan Z, Ramanan P, Takeda S, Frosch MP, Wegmann S, Gomez-Isla T. iScience. 2021 Jan 13;24(2):102058. doi: 10.1016/j.isci.2021.102058.


Continuous Glibenclamide Prevents Hemorrhagic Transformation in a Rodent Model of Severe Ischemia-Reperfusion.
Igarashi T, Sastre C, Wolcott Z, Kimberly WT. J Stroke Cerebrovasc Dis. 2021 Jan 12;30(3):105595. doi: 10.1016/j.jstrokecerebrovasdis.2020.105595. 


Implications of COVID-19 sequelae for health-care personnel.
Praschan N, Josephy-Hernandez S, Kim DD, Kritzer MD, Mukerji S, Newhouse A, Pasinski M, Chemali Z. Lancet Respir Med. 2021 Jan 11:S2213-2600(20)30575-0. doi: 10.1016/S2213-2600(20)30575-0.


Auditory cues reveal intended movement information in middle frontal gyrus neuronal ensemble activity of a person with tetraplegia.
Hosman T, Hynes JB, Saab J, Wilcoxen KG, Buchbinder BR, Schmansky N, Cash SS, Eskandar EN, Simeral JD, Franco B, Kelemen J, Vargas-Irwin CE, Hochberg LR. Sci Rep. 2021 Jan 11;11(1):98. doi: 10.1038/s41598-020-77616-8.


The paradoxical effect of COVID-19 outbreak on loneliness.
Bartrés-Faz D, Macià D, Cattaneo G, Borràs R, Tarrero C, Solana J, Tormos JM, Pascual-Leone A. BJPsych Open. 2021 Jan 11;7(1):e30. doi: 10.1192/bjo.2020.163.


Beware of Optimism Bias in the Context of the COVID-19 Pandemic.
Pascual-Leone A, Cattaneo G, Macià D, Solana J, Tormos JM, Bartrés-Faz D. Ann Neurol. 2021 Jan 11. doi: 10.1002/ana.26001.


Mutations causing Lopes-Maciel-Rodan Syndrome are huntingtin hypomorphs.
Jung R, Lee Y, Barker D, Correia K, Shin B, Loupe J, Collins RL, Lucente D, Ruliera J, Gillis T, Mysore JS, Rodan L, Picker J, Lee JM, Howland D, Lee R, Kwak S, MacDonald ME, Gusella JF, Seong IS. Hum Mol Genet. 2021 Jan 11:ddaa283. doi: 10.1093/hmg/ddaa283.


Considerations on clinical biomarkers analyses using immunoassays.
Moscovitch-Lopatin M. J Immunoassay Immunochem. 2021 Jan 11:1-3. doi: 10.1080/15321819.2021.1872358.


Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration.
Patnaik D, Pao PC, Zhao WN, Silva MC, Hylton NK, Chindavong PS, Pan L, Tsai LH, Haggarty SJ. ACS Chem Neurosci. 2021 Jan 8. doi: 10.1021/acschemneuro.0c00308.


Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin.
Cheah PS, Prabhakar S, Yellen D, Beauchamp RL, Zhang X, Kasamatsu S, Bronson RT, Thiele EA, Kwiatkowski DJ, Stemmer-Rachamimov A, György B, Ling KH, Kaneki M, Tannous BA, Ramesh V, Maguire CA, Breakefield XO. Sci Adv. 2021 Jan 8;7(2):eabb1703. doi: 10.1126/sciadv.abb1703.


Inequities in neurology amplified by the COVID-19 pandemic.
Nolen L, Mejia NI. Nat Rev Neurol. 2021 Jan 7:1-2. doi: 10.1038/s41582-020-00452-x.


Tractography-Pathology Correlations in Traumatic Brain Injury: A TRACK-TBI Study.
Nolan AL, Petersen C, Iacono D, Mac Donald CL, Mukherjee P, van der Kouwe A, Jain S, Stevens A, Diamond B, Wang R, Markowitz AJ, Fischl B, Perl D, Manley GT, Keene CD, Diaz-Arrastia R, Edlow BL. J Neurotrauma. 2021 Jan 7. doi: 10.1089/neu.2020.7373.


Case 26-2020: A Woman with Altered Mental Status and Left-Sided Weakness. Reply.
Singhal AB, Mukerji SS, Chwalisz BK. N Engl J Med. 2021 Jan 7;384(1):92. doi: 10.1056/NEJMc2030849.


Association of CSF Biomarkers with Hippocampal-dependent Memory in Preclinical Alzheimer Disease.
Trelle AN, Carr VA, Wilson EN, Swarovski MS, Hunt MP, Toueg TN, Tran TT, Channappa D, Corso NK, Thieu MK, Jayakumar M, Nadiadwala A, Guo W, Tanner NJ, Bernstein JD, Litovsky CP, Guerin SA, Khazenzon AM, Harrison MB, Rutt BK, Deutsch GK, Chin FT, Davidzon GA, Hall JN, Sha SJ, Fredericks CA, Andreasson KI, Kerchner GA, Wagner AD, Mormino EC. Neurology. 2021 Jan 6:10.1212/WNL.0000000000011477. doi: 10.1212/WNL.0000000000011477.


Beyond gait and balance: urinary and bowel dysfunction in X-linked adrenoleukodystrophy.
Corre CS, Grant N, Sadjadi R, Hayden D, Becker C, Gomery P, Eichler FS. Orphanet J Rare Dis. 2021 Jan 6;16(1):14. doi: 10.1186/s13023-020-01596-1.


Diminished Learning Over Repeated Exposures (LORE) in preclinical Alzheimer's disease.
Samaroo A, Amariglio RE, Burnham S, Sparks P, Properzi M, Schultz AP, Buckley R, Johnson KA, Sperling RA, Rentz DM, Papp KV. Alzheimers Dement (Amst). 2021 Jan 5;12(1):e12132. doi: 10.1002/dad2.12132. eCollection 2020.


MRI Characteristics of NMO, MOG and MS Related Optic Neuritis.
Winter A, Chwalisz B. Semin Ophthalmol. 2021 Jan 4:1-10. doi: 10.1080/08820538.2020.1866027.  


Common and distinct neural substrates of sentence production and comprehension.
Lukic S, Thompson CK, Barbieri E, Chiappetta B, Bonakdarpour B, Kiran S, Rapp B, Parrish TB, Caplan D. Neuroimage. 2021 Jan 1;224:117374. doi: 10.1016/j.neuroimage.2020.117374.


Neuroimaging in Frontotemporal Lobar Degeneration: Research and Clinical Utility.
Dev SI, Dickerson BC, Touroutoglou A. Adv Exp Med Biol. 2021;1281:93-112. doi: 10.1007/978-3-030-51140-1_7.


APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches.
Serrano-Pozo A, Das S, Hyman BT. Lancet Neurol. 2021 Jan;20(1):68-80. doi: 10.1016/S1474-4422(20)30412-9.


A Synergistic Engineering Approach to Build Human Brain Spheroids.
von Maydell D, Jorfi M. Methods Mol Biol. 2021;2258:151-169. doi: 10.1007/978-1-0716-1174-6_11. 


Huntington's Disease Pathogenesis: Two Sequential Components.
Hong EP, MacDonald ME, Wheeler VC, Jones L, Holmans P, Orth M, Monckton DG, Long JD, Kwak S, Gusella JF, Lee JM. J Huntingtons Dis. 2021;10(1):35-51. doi: 10.3233/JHD-200427.  


The role of biomarkers and neuroimaging in ischemic/hemorrhagic risk assessment for cardiovascular/cerebrovascular disease prevention.
Gokcal E, Horn MJ, Gurol ME. Handb Clin Neurol. 2021;177:345-357. doi: 10.1016/B978-0-12-819814-8.00021-4.


Modifiers of CAG/CTG Repeat Instability: Insights from Mammalian Models.
Wheeler VC, Dion V. J Huntingtons Dis. 2021;10(1):123-148. doi: 10.3233/JHD-200426.


Neuroimaging in Frontotemporal Lobar Degeneration: Research and Clinical Utility.
Dev SI, Dickerson BC, Touroutoglou A. Adv Exp Med Biol. 2021;1281:93-112. doi: 10.1007/978-3-030-51140-1_7.


The Computerized Cognitive Composite (C3) in an Alzheimer's Disease Secondary Prevention Trial.
Papp KV, Rentz DM, Maruff P, Sun CK, Raman R, Donohue MC, Schembri A, Stark C, Yassa MA, Wessels AM, Yaari R, Holdridge KC, Aisen PS, Sperling RA. J Prev Alzheimers Dis. 2021;8(1):59-67. doi: 10.14283/jpad.2020.38.


Item-Level Investigation of Participant and Study Partner Report on the Cognitive Function Index from the A4 Study Screening Data.
Amariglio RE, Sikkes SAM, Marshall GA, Buckley RF, Gatchel JR, Johnson KA, Rentz DM, Donohue MC, Raman R, Sun CK, Yaari R, Holdridge KC, Sims JR, Grill JD, Aisen PS, Sperling RA. J Prev Alzheimers Dis. 2021;8(3):257-262. doi: 10.14283/jpad.2021.8.


Endocrine dysfunction in adrenoleukodystrophy.
Engelen M, Kemp S, Eichler F. Handb Clin Neurol. 2021;182:257-267. doi: 10.1016/B978-0-12-819973-2.00018-6.


Emotional disorders and the cerebellum: Neurobiological substrates, neuropsychiatry, and therapeutic implications.
Schmahmann JD. Handb Clin Neurol. 2021;183:109-154. doi: 10.1016/B978-0-12-822290-4.00016-5.

 Earlier Publications