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In 2020, the Mass General Neurology faculty published more than 1,000 papers in journals like Neurology, Stroke, and JAMA Neurology, and we are on track to surpass that record for 2021. Our research efforts advance our mission to rapidly discover new treatments to reduce and eliminate the devastating impact of neurological disorders.

Motor tract reorganization after acute central nervous system injury: a translational perspective.
Takase H, Regenhardt RW. Neural Regen Res. 2021 Jun;16(6):1144-1149. doi: 10.4103/1673-5374.300330.


The use of hydrogel-delivered extracellular vesicles in recovery of motor function in stroke: a testable experimental hypothesis for clinical translation including behavioral and neuroimaging assessment approaches.
Tsintou M, Dalamagkas K, Moore TL, Rathi Y, Kubicki M, Rosene DL, Makris N. Neural Regen Res. 2021 Apr;16(4):605-613. doi: 10.4103/1673-5374.295269.


Decomposition of Reaching Movements Enables Detection and Measurement of Ataxia.
Oubre B, Daneault JF, Whritenour K, Khan NC, Stephen CD, Schmahmann JD, Lee SI, Gupta AS. Cerebellum. 2021 Mar 2. doi: 10.1007/s12311-021-01247-6.


Abnormal dynamic functional connectivity is linked to recovery after acute ischemic stroke.
Bonkhoff AK, Schirmer MD, Bretzner M, Etherton M, Donahue K, Tuozzo C, Nardin M, Giese AK, Wu O, D Calhoun V, Grefkes C, Rost NS. Hum Brain Mapp. 2021 Mar 2. doi: 10.1002/hbm.25366.


The Quest for Covert Consciousness: Bringing Neuroethics to the Bedside.
Young MJ, Edlow BL. Neurology. 2021 Mar 2:10.1212/WNL.0000000000011734. doi: 10.1212/WNL.0000000000011734.


Clinical, radiological and genomic features and targeted therapy in BRAF V600E mutant adult glioblastoma.
Lim-Fat MJ, Song KW, Iorgulescu JB, Andersen BM, Forst DA, Jordan JT, Gerstner ER, Reardon DA, Wen PY, Arrillaga-Romany I. J Neurooncol. 2021 Mar 1. doi: 10.1007/s11060-021-03719-5. 


Holding Out Hope After Traumatic Brain Injury.
Kim JA, Sheth KN. JAMA Neurol. 2021 Mar 1. doi: 10.1001/jamaneurol.2020.5328.


Stroke in Pregnancy: A Multidisciplinary Approach.
Camargo EC, Singhal AB. Obstet Gynecol Clin North Am. 2021 Mar;48(1):75-96. doi: 10.1016/j.ogc.2020.11.004. 


Neuro-ophthalmic Complications of Immune-Checkpoint Inhibitors.
Mukharesh L, Chwalisz BK. Semin Ophthalmol. 2021 Feb 27:1-9. doi: 10.1080/08820538.2021.1890796.  


Bright spotty lesions as an imaging marker for neuromyelitis optica spectrum disorder.
Salama S, Levy M. Mult Scler. 2021 Feb 26:1352458521994259. doi: 10.1177/1352458521994259.


Teleneurology-Enabled Determination of Death by Neurologic Criteria After Cardiac Arrest or Severe Neurologic Injury.
Matiello M, Turner AC, Estrada J, Whitney CM, Kitch BT, Lee PT, Girkar U, Palacios R, Singla P, Schwamm L. Neurology. 2021 Feb 26:10.1212/WNL.0000000000011751. doi: 10.1212/WNL.0000000000011751. 


The combined use of steroids and immune checkpoint inhibitors in brain metastasis patients: a systematic review and meta-analysis.
Jessurun CAC, Hulsbergen AFC, de Wit AE, Tewarie IA, Snijders TJ, Verhoeff J, Phillips J, Reardon DA, Mekary RA, Broekman MLD. Neuro Oncol. 2021 Feb 25:noab046. doi: 10.1093/neuonc/noab046.


Machine and deep learning in MS research are just powerful statistics - No.
Healy BC. Mult Scler. 2021 Feb 24:1352458520978648. doi: 10.1177/1352458520978648.


One-Year Medicare Costs Associated With Delirium in Older Patients Undergoing Major Elective Surgery.
Gou RY, Hshieh TT, Marcantonio ER, Cooper Z, Jones RN, Travison TG, Fong TG, Abdeen A, Lange J, Earp B, Schmitt EM, Leslie DL, Inouye SK; SAGES Study Group. JAMA Surg. 2021 Feb 24. doi: 10.1001/jamasurg.2020.7260.


Understanding Sunflower syndrome: Results of an online questionnaire.
Barnett JR, Fleming BM, Doshi SP, Freedman J, Ambrosio NR, Geenen KR, Bruno PL, Thiele EA. Epilepsy Behav. 2021 Feb 24;117:107856. doi: 10.1016/j.yebeh.2021.107856.  


Association of Memory Impairment with Concomitant Tau Pathology in Patients with Cerebral Amyloid Angiopathy.
Schoemaker D, Charidimou A, Zanon Zotin MC, Raposo N, Johnson KA, Sanchez JS, Greenberg SM, Viswanathan A. Neurology. 2021 Feb 24:10.1212/WNL.0000000000011745. doi: 10.1212/WNL.0000000000011745.


Ptosis as Clinical Presentation in a Patient With Emery-Dreifuss Muscular Dystrophy Type 5.
Douglas KAA, Douglas VP, Gaier ED, Chwalisz BK. J Neuroophthalmol. 2021 Feb 19. doi: 10.1097/WNO.0000000000001187.


A high proportion of novel ACAN mutations and their prevalence in a large cohort of Chinese short stature children.
Lin L, Li M, Luo J, Li P, Zhou S, Yang Y, Chen K, Weng Y, Ge X, Mireguli M, Wei H, Yang H, Li G, Sun Y, Cui L, Zhang S, Chen J, Zeng G, Xu L, Luo X, Shen Y. J Clin Endocrinol Metab. 2021 Feb 19:dgab088. doi: 10.1210/clinem/dgab088.  


Serum NFL levels predict progression of motor impairment and reduction in putamen dopamine transporter binding ratios in de novo Parkinson's disease: An 8-year longitudinal study.
Ye R, Locascio JJ, Goodheart AE, Quan M, Zhang B, Gomperts SN. Parkinsonism Relat Disord. 2021 Feb 17;85:11-16. doi: 10.1016/j.parkreldis.2021.02.008.


Optical coherence tomography of arteriolar diameter and capillary perfusion during spreading depolarizations.
Anzabi M, Li B, Wang H, Kura S, Sakadžić S, Boas D, Østergaard L, Ayata C. J Cereb Blood Flow Metab. 2021 Feb 16:271678X21994013. doi: 10.1177/0271678X21994013.


Is the COVID-19 pandemic magnifying disparities in stroke treatment?
Regenhardt RW, Young MJ, Leslie-Mazwi TM. J Neurointerv Surg. 2021 Feb 16:neurintsurg-2021-017292. doi: 10.1136/neurintsurg-2021-017292.   


Regional Changes in Patterns of Stroke Presentation During the COVID-19 Pandemic.
Etherton MR, Zachrison KS, Yan Z, Sveikata L, Bretzner M, Estrada J, Viswanathan A, Singhal AB, Schwamm LH. Stroke. 2021 Feb 16:STROKEAHA120031300. doi: 10.1161/STROKEAHA.120.031300.


Association of Digital Clock Drawing with PET Amyloid and Tau Pathology in Normal Older Adults.
Rentz DM, Papp KV, Mayblyum DV, Sanchez JS, Klein H, Souillard-Mandar W, Sperling RA, Johnson KA. Neurology. 2021 Feb 15:10.1212/WNL.0000000000011697. doi: 10.1212/WNL.0000000000011697. 


Regional prefrontal cortical atrophy predicts specific cognitive-behavioral symptoms in ALS-FTD.
Ratti E, Domoto-Reilly K, Caso C, Murphy A, Brickhouse M, Hochberg D, Makris N, Cudkowicz ME, Dickerson BC. Brain Imaging Behav. 2021 Feb 15. doi: 10.1007/s11682-021-00456-1.


Machine learning identifies candidates for drug repurposing in Alzheimer's disease.
Rodriguez S, Hug C, Todorov P, Moret N, Boswell SA, Evans K, Zhou G, Johnson NT, Hyman BT, Sorger PK, Albers MW, Sokolov A. Nat Commun. 2021 Feb 15;12(1):1033. doi: 10.1038/s41467-021-21330-0. 


Workshop report. Circadian rhythm sleep-wake disorders: gaps and opportunities.
Duffy JF, Abbott SM, Burgess HJ, Crowley SJ, Emens JS, Epstein LJ, Gamble KL, Hasler BP, Kristo DA, Malkani RG, Rahman SA, Thomas SJ, Wyatt JK, Zee PC, Klerman EB. Sleep. 2021 Feb 14:zsaa281. doi: 10.1093/sleep/zsaa281.


Evaluation of Fluorinated Cromolyn Derivatives as Potential Therapeutics for Alzheimer's Disease.
Shoup TM, Griciuc A, Normandin MD, Quinti L, Walsh LV, Dhaynaut M, Moon SH, Guehl NJ, Brugarolas P, Elmaleh DR, Fakhri GE, Tanzi RE. J Alzheimers Dis. 2021 Feb 12. doi: 10.3233/JAD-201419.


A Virtual, Randomized, Control Trial of a Digital Therapeutic for Speech, Language, and Cognitive Intervention in Post-stroke Persons With Aphasia.
Braley M, Pierce JS, Saxena S, De Oliveira E, Taraboanta L, Anantha V, Lakhan SE, Kiran S. Front Neurol. 2021 Feb 12;12:626780. doi: 10.3389/fneur.2021.626780.


Comparison of Two Clinical Upper Motor Neuron Burden Rating Scales in ALS Using Quantitative Brain Imaging.
Makary MM, Weerasekara A, Rodham H, Hightower BG, Tseng CJ, Chan J, Chew S, Paganoni S, Ratai EM, Zürcher NR, Hooker JM, Atassi N, Babu S. ACS Chem Neurosci. 2021 Feb 12. doi: 10.1021/acschemneuro.0c00772.


18F-AV-1451 positron emission tomography in neuropathological substrates of corticobasal syndrome.
Goodheart AE, Locascio JJ, Samore WR, Collins JA, Brickhouse M, Schultz A, Touroutoglou A, Johnson KA, Frosch MP, Growdon JH, Dickerson BC, Gomperts SN. Brain. 2021 Feb 12;144(1):266-277. doi: 10.1093/brain/awaa383. 


Amyloid PET imaging in self-identified non-Hispanic Blacks from the Anti-Amyloid in Asymptomatic Alzheimer's Disease (A4) Study.
Deters K, Napolioni V, Sperling RA, Greicius MD, Mayeux R, Hohman T, Mormino EC. Neurology. 2021 Feb 10:10.1212/WNL.0000000000011599. doi: 10.1212/WNL.0000000000011599.


Validation of an Internationally Derived Patient Severity Phenotype to Support COVID-19 Analytics from Electronic Health Record Data.
Klann JG, Weber GM, Estiri H, Moal B, Avillach P, Hong C, Castro V, Maulhardt T, Tan ALM, Geva A, Beaulieu-Jones BK, Malovini A, South AM, Visweswaran S, Omenn GS, Ngiam KY, Mandl KD, Boeker M, Olson KL, Mowery DL, Morris M, Follett RW, Hanauer DA, Bellazzi R, Moore JH, Loh NW, Bell DS, Wagholikar KB, Chiovato L, Tibollo V, Rieg S, Li ALLJ, Jouhet V, Schriver E, Samayamuthu MJ, Xia Z, Hutch M, Luo Y; Consortium for Clinical Characterization of COVID-19 by EHR (4CE) (CONSORTIA AUTHOR), Kohane IS, Brat GA, Murphy SN. J Am Med Inform Assoc. 2021 Feb 10:ocab018. doi: 10.1093/jamia/ocab018. 


Implementation of high-cadence cycling for Parkinson's disease in the community setting: A pragmatic feasibility study.
McKee KE, Johnson RK, Chan J, Wills AM. Brain Behav. 2021 Feb 9:e02053. doi: 10.1002/brb3.2053.


Is MRI in the Angiographic Suite a New Frontier?
Lev MH, Leslie-Mazwi TM. Radiology. 2021 Feb 9:204563. doi: 10.1148/radiol.2021204563.  


Mind the translational gap: using iPS cell models to bridge from genetic discoveries to perturbed pathways and therapeutic targets.
Pintacuda G, Martín JM, Eggan KC. Mol Autism. 2021 Feb 8;12(1):10. doi: 10.1186/s13229-021-00417-x.  


Neuropsychiatric symptoms in a occipito-temporal infarction with remarkable long-term functional recovery.
Tanev KS, Federico LE, Sydnor VJ, Leveroni CL, Hassan K, Biffi A. Cortex. 2021 Feb 6;137:205-214. doi: 10.1016/j.cortex.2021.01.013.


Reimagining Stroke Rehabilitation and Recovery Across the Care Continuum: Results from a Design-Thinking Workshop to Identify Challenges and Propose Solutions.
DiCarlo JA, Gheihman G, Lin DJ; 2019 Northeast Cerebrovascular Consortium Conference Stroke Recovery Workshop Participants. Arch Phys Med Rehabil. 2021 Feb 5:S0003-9993(21)00142-8. doi: 10.1016/j.apmr.2021.01.074.


Predicting COVID-19 mortality with electronic medical records.
Estiri H, Strasser ZH, Klann JG, Naseri P, Wagholikar KB, Murphy SN. NPJ Digit Med. 2021 Feb 4;4(1):15. doi: 10.1038/s41746-021-00383-x.


Functional Dystonia: Differentiation From Primary Dystonia and Multidisciplinary Treatments.
Frucht L, Perez DL, Callahan J, MacLean J, Song PC, Sharma N, Stephen CD. Front Neurol. 2021 Feb 4;11:605262. doi: 10.3389/fneur.2020.605262. eCollection 2020.


CTA Protocols in a Telestroke Network Improve Efficiency for Both Spoke and Hub Hospitals.
Yu AT, Regenhardt RW, Whitney C, Schwamm LH, Patel AB, Stapleton CJ, Viswanathan A, Hirsch JA, Lev M, Leslie-Mazwi TM. AJNR Am J Neuroradiol. 2021 Feb 4. doi: 10.3174/ajnr.A6950.


The role of innate immune genes in Alzheimer's disease.
Griciuc A, Tanzi RE. Curr Opin Neurol. 2021 Feb 3. doi: 10.1097/WCO.0000000000000911. 


Lacunes, Microinfarcts and Vascular Dysfunction in Cerebral Amyloid Angiopathy.
Gokcal E, Horn MJ, van Veluw SJ, Frau-Pascual A, Das AS, Pasi M, Fotiadis P, Warren AD, Schwab K, Rosand J, Viswanathan A, Polimeni JR, Greenberg SM, Gurol ME. Neurology. 2021 Feb 3:10.1212/WNL.0000000000011631. doi: 10.1212/WNL.0000000000011631.


Challenges and Opportunities in Multimodal Monitoring and Data Analytics in Traumatic Brain Injury.
Foreman B, Lissak IA, Kamireddi N, Moberg D, Rosenthal ES. Curr Neurol Neurosci Rep. 2021 Feb 2;21(3):6. doi: 10.1007/s11910-021-01098-y.


Patterns of antidepressant therapy and clinical outcomes among ischaemic stroke survivors.
Etherton MR, Shah S, Haolin X, Xian Y, Maisch L, Hannah D, Lindholm B, Lytle B, Thomas L, Smith EE, Fonarow GC, Schwamm LH, Bhatt DL, Hernandez AF, O'Brien EC. Stroke Vasc Neurol. 2021 Feb 1:svn-2020-000691. doi: 10.1136/svn-2020-000691


Clinical Characteristics and Outcomes Associated With Oral Anticoagulant Use Among Patients Hospitalized With Intracerebral Hemorrhage.
Xian Y, Zhang S, Inohara T, Grau-Sepulveda M, Matsouaka RA, Peterson ED, Piccini JP, Smith EE, Sheth KN, Bhatt DL, Fonarow GC, Schwamm LH. JAMA Netw Open. 2021 Feb 1;4(2):e2037438. doi: 10.1001/jamanetworkopen.2020.37438.


Robust Stability of Melatonin Circadian Phase, Sleep Metrics, and Chronotype Across Months in Young Adults Living in Real-World Settings.
McHill AW, Sano A, Hilditch CJ, Barger LK, Czeisler CA, Picard R, Klerman EB. J Pineal Res. 2021 Feb 1:e12720. doi: 10.1111/jpi.12720.


Language preference does not influence stroke patients' symptom recognition or emergency care time metrics.
Zachrison KS, Natsui S, Luan Erfe BM, Mejia NI, Schwamm LH. Am J Emerg Med. 2021 Feb;40:177-180. doi: 10.1016/j.ajem.2020.10.064.


The best matrix for the brain: advances in secondary CNS lymphoma.Dietrich J. Lancet Haematol. 2021 Feb;8(2):e96-e97. doi: 10.1016/S2352-3026(20)30431-2.  


Inequities in neurology amplified by the COVID-19 pandemic.
Nolen L, Mejia NI. Nat Rev Neurol. 2021 Feb;17(2):67-68. doi: 10.1038/s41582-020-00452-x.


Author Correction: Evaluating drug targets through human loss-of-function genetic variation.
Minikel EV, Karczewski KJ, Martin HC, Cummings BB, Whiffin N, Rhodes D, Alföldi J, Trembath RC, van Heel DA, Daly MJ; Genome Aggregation Database Production Team; Genome Aggregation Database Consortium, Schreiber SL, MacArthur DG. Nature. 2021 Feb;590(7846):E56. doi: 10.1038/s41586-020-03177-5.


Author Correction: A structural variation reference for medical and population genetics.
Collins RL, Brand H, Karczewski KJ, Zhao X, Alföldi J, Francioli LC, Khera AV, Lowther C, Gauthier LD, Wang H, Watts NA, Solomonson M, O'Donnell-Luria A, Baumann A, Munshi R, Walker M, Whelan CW, Huang Y, Brookings T, Sharpe T, Stone MR, Valkanas E, Fu J, Tiao G, Laricchia KM, Ruano-Rubio V, Stevens C, Gupta N, Cusick C, Margolin L; Genome Aggregation Database Production Team; Genome Aggregation Database Consortium, Taylor KD, Lin HJ, Rich SS, Post WS, Chen YI, Rotter JI, Nusbaum C, Philippakis A, Lander E, Gabriel S, Neale BM, Kathiresan S, Daly MJ, Banks E, MacArthur DG, Talkowski ME. Nature. 2021 Feb;590(7846):E55. doi: 10.1038/s41586-020-03176-6.


Author Correction: Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.
Dujardin S, Commins C, Lathuiliere A, Beerepoot P, Fernandes AR, Kamath TV, De Los Santos MB, Klickstein N, Corjuc DL, Corjuc BT, Dooley PM, Viode A, Oakley DH, Moore BD, Mullin K, Jean-Gilles D, Clark R, Atchison K, Moore R, Chibnik LB, Tanzi RE, Frosch MP, Serrano-Pozo A, Elwood F, Steen JA, Kennedy ME, Hyman BT. Nat Med. 2021 Jan 29. doi: 10.1038/s41591-021-01251-7.


Uridine-responsive epileptic encephalopathy due to inherited variants in CAD: A Tale of Two Siblings.
McGraw CM, Mahida S, Jayakar P, Koh HY, Taylor A, Resnick T, Rodan L, Schwartz MA, Ejaz A, Sankaran VG, Berry G, Poduri A. Ann Clin Transl Neurol. 2021 Jan 26. doi: 10.1002/acn3.51272.  


Case Report: Deep Brain Stimulation to the Ventral Internal Capsule/Ventral Striatum Induces Repeated Transient Episodes of Voltage-Dependent Tourette-Like Behaviors.
Camprodon JA, Chou T, Testo AA, Deckersbach T, Scharf JM, Dougherty DD. Front Hum Neurosci. 2021 Jan 25;14:590379. doi: 10.3389/fnhum.2020.590379.


Serum neurofilament levels and patient-reported outcomes in multiple sclerosis.
Galetta K, Deshpande C, Healy BC, Glanz B, Ziehn M, Saxena S, Paul A, Saleh F, Collins M, Gaitan-Walsh P, Castro-Mendoza P, Weiner HL, Chitnis T. Ann Clin Transl Neurol. 2021 Jan 25. doi: 10.1002/acn3.51305. 


A transdiagnostic and biopsychosocial-informed perspective across functional seizures and functional movement disorder.
Saxena A, Perez DL. Epilepsy Behav. 2021 Jan 25:107749. doi: 10.1016/j.yebeh.2020.107749.


Unmasking Covert Language Processing in the Intensive Care Unit with EEG.
Edlow BL, Naccache L. Ann Neurol. 2021 Jan 25. doi: 10.1002/ana.26030.


Child Neurology: Intractable Epilepsy and Transient Deficits in a Patient with a History of HSV Encephalitis.
Manzano GS, Danish HH, Chu CJ, Kimchi EY. Neurology. 2021 Jan 25:10.1212/WNL.0000000000011606. doi: 10.1212/WNL.0000000000011606. 


Electroencephalography, Hospital Complications, and Longitudinal Outcomes After Subarachnoid Hemorrhage.
Lissak IA, Locascio JJ, Zafar SF, Schleicher RL, Patel AB, Leslie-Mazwi T, Stapleton CJ, Koch MJ, Kim JA, Anderson K, Rosand J, Westover MB, Kimberly WT, Rosenthal ES. Neurocrit Care. 2021 Jan 22. doi: 10.1007/s12028-020-01177-x. 


MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols.
Wilcock D, Jicha G, Blacker D, Albert MS, D'Orazio LM, Elahi FM, Fornage M, Hinman JD, Knoefel J, Kramer J, Kryscio RJ, Lamar M, Moghekar A, Prestopnik J, Ringman JM, Rosenberg G, Sagare A, Satizabal CL, Schneider J, Seshadri S, Sur S, Tracy RP, Yasar S, Williams V, Singh H, Mazina L, Helmer KG, Corriveau RA, Schwab K, Kivisäkk P, Greenberg SM; MarkVCID Consortium. Alzheimers Dement. 2021 Jan 21. doi: 10.1002/alz.12215. 


Intranasal delivery of experimental compounds in orthotopic brain tumor mouse models.
Eyme KM, Carvalho L, Badr CE. STAR Protoc. 2021 Jan 21;2(1):100290. doi: 10.1016/j.xpro.2020.100290. eCollection 2021 Mar 19.


MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols.
Lu H, Kashani AH, Arfanakis K, Caprihan A, DeCarli C, Gold BT, Li Y, Maillard P, Satizabal CL, Stables L, Wang DJJ, Corriveau RA, Singh H, Smith EE, Fischl B, van der Kouwe A, Schwab K, Helmer KG, Greenberg SM; MarkVCID Consortium. Alzheimers Dement. 2021 Jan 21. doi: 10.1002/alz.12216. 


MRI Lesion State Modulates the Relationship Between Serum Neurofilament Light and Age in Multiple Sclerosis.
Rosso M, Healy BC, Saxena S, Paul A, Bjornevik K, Kuhle J, Benkert P, Leppert D, Guttmann C, Bakshi R, Weiner HL, Chitnis T. J Neuroimaging. 2021 Jan 21. doi: 10.1111/jon.12826.


Should neurosurgeons continue to work in the absence of personal protective equipment during the COVID-19 era?
Eijkholt M, Hulsbergen A, Muskens I, Mathiesen TI, Bolger C, Feldman Z, Kitchen N, Samprón N, Sandvik U, Tisell M, Broekman M. Acta Neurochir (Wien). 2021 Jan 20. doi: 10.1007/s00701-021-04703-8


The cortical origin and initial spread of medial temporal tauopathy in Alzheimer's disease assessed with positron emission tomography.
Sanchez JS, Becker JA, Jacobs HIL, Hanseeuw BJ, Jiang S, Schultz AP, Properzi MJ, Katz SR, Beiser A, Satizabal CL, O'Donnell A, DeCarli C, Killiany R, El Fakhri G, Normandin MD, Gómez-Isla T, Quiroz YT, Rentz DM, Sperling RA, Seshadri S, Augustinack J, Price JC, Johnson KA. Sci Transl Med. 2021 Jan 20;13(577):eabc0655. doi: 10.1126/scitranslmed.abc0655.


Breakdowns in Informativeness of Naturalistic Speech Production in Primary Progressive Aphasia.
Gallée J, Cordella C, Fedorenko E, Hochberg D, Touroutoglou A, Quimby M, Dickerson BC. Brain Sci. 2021 Jan 20;11(2):E130. doi: 10.3390/brainsci11020130.


Machine Learning-Driven Metabolomic Evaluation of Cerebrospinal Fluid: Insights Into Poor Outcomes After Aneurysmal Subarachnoid Hemorrhage.
Koch M, Acharjee A, Ament Z, Schleicher R, Bevers M, Stapleton C, Patel A, Kimberly WT. Neurosurgery. 2021 Jan 19:nyaa557. doi: 10.1093/neuros/nyaa557. 


Fibroblasts from idiopathic Parkinson's disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2.
Thomas R, Moloney EB, Macbain ZK, Hallett PJ, Isacson O. Mol Brain. 2021 Jan 19;14(1):16. doi: 10.1186/s13041-020-00712-3.  


Circadian and Sleep Dysfunctions in Neurodegenerative Disorders-An Update.
Fifel K, Videnovic A. Front Neurosci. 2021 Jan 18;14:627330. doi: 10.3389/fnins.2020.627330.


Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19.
Conklin J, Frosch MP, Mukerji SS, Rapalino O, Maher MD, Schaefer PW, Lev MH, Gonzalez RG, Das S, Champion SN, Magdamo C, Sen P, Harrold GK, Alabsi H, Normandin E, Shaw B, Lemieux JE, Sabeti PC, Branda JA, Brown EN, Westover MB, Huang SY, Edlow BL. J Neurol Sci. 2021 Jan 15;421:117308. doi: 10.1016/j.jns.2021.117308.


Focal sleep spindle deficits reveal focal thalamocortical dysfunction and predict cognitive deficits in childhood epilepsy with centrotemporal spikes.
Kramer MA, Stoyell SM, Chinappen D, Ostrowski LM, Spencer ER, Morgan AK, Emerton BC, Jing J, Westover MB, Eden UT, Stickgold R, Manoach DS, Chu CJ. J Neurosci. 2021 Jan 14:JN-RM-2009-20. doi: 10.1523/JNEUROSCI.2009-20.2020.  


Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation.
Amaral AC, Perez-Nievas BG, Siao Tick Chong M, Gonzalez-Martinez A, Argente-Escrig H, Rubio-Guerra S, Commins C, Muftu S, Eftekharzadeh B, Hudry E, Fan Z, Ramanan P, Takeda S, Frosch MP, Wegmann S, Gomez-Isla T. iScience. 2021 Jan 13;24(2):102058. doi: 10.1016/j.isci.2021.102058.


Continuous Glibenclamide Prevents Hemorrhagic Transformation in a Rodent Model of Severe Ischemia-Reperfusion.
Igarashi T, Sastre C, Wolcott Z, Kimberly WT. J Stroke Cerebrovasc Dis. 2021 Jan 12;30(3):105595. doi: 10.1016/j.jstrokecerebrovasdis.2020.105595. 


Implications of COVID-19 sequelae for health-care personnel.
Praschan N, Josephy-Hernandez S, Kim DD, Kritzer MD, Mukerji S, Newhouse A, Pasinski M, Chemali Z. Lancet Respir Med. 2021 Jan 11:S2213-2600(20)30575-0. doi: 10.1016/S2213-2600(20)30575-0.


Auditory cues reveal intended movement information in middle frontal gyrus neuronal ensemble activity of a person with tetraplegia.
Hosman T, Hynes JB, Saab J, Wilcoxen KG, Buchbinder BR, Schmansky N, Cash SS, Eskandar EN, Simeral JD, Franco B, Kelemen J, Vargas-Irwin CE, Hochberg LR. Sci Rep. 2021 Jan 11;11(1):98. doi: 10.1038/s41598-020-77616-8.


The paradoxical effect of COVID-19 outbreak on loneliness.
Bartrés-Faz D, Macià D, Cattaneo G, Borràs R, Tarrero C, Solana J, Tormos JM, Pascual-Leone A. BJPsych Open. 2021 Jan 11;7(1):e30. doi: 10.1192/bjo.2020.163.


Beware of Optimism Bias in the Context of the COVID-19 Pandemic.
Pascual-Leone A, Cattaneo G, Macià D, Solana J, Tormos JM, Bartrés-Faz D. Ann Neurol. 2021 Jan 11. doi: 10.1002/ana.26001.


Mutations causing Lopes-Maciel-Rodan Syndrome are huntingtin hypomorphs.
Jung R, Lee Y, Barker D, Correia K, Shin B, Loupe J, Collins RL, Lucente D, Ruliera J, Gillis T, Mysore JS, Rodan L, Picker J, Lee JM, Howland D, Lee R, Kwak S, MacDonald ME, Gusella JF, Seong IS. Hum Mol Genet. 2021 Jan 11:ddaa283. doi: 10.1093/hmg/ddaa283.


Considerations on clinical biomarkers analyses using immunoassays.
Moscovitch-Lopatin M. J Immunoassay Immunochem. 2021 Jan 11:1-3. doi: 10.1080/15321819.2021.1872358.


Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration.
Patnaik D, Pao PC, Zhao WN, Silva MC, Hylton NK, Chindavong PS, Pan L, Tsai LH, Haggarty SJ. ACS Chem Neurosci. 2021 Jan 8. doi: 10.1021/acschemneuro.0c00308.


Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin.
Cheah PS, Prabhakar S, Yellen D, Beauchamp RL, Zhang X, Kasamatsu S, Bronson RT, Thiele EA, Kwiatkowski DJ, Stemmer-Rachamimov A, György B, Ling KH, Kaneki M, Tannous BA, Ramesh V, Maguire CA, Breakefield XO. Sci Adv. 2021 Jan 8;7(2):eabb1703. doi: 10.1126/sciadv.abb1703.


Inequities in neurology amplified by the COVID-19 pandemic.
Nolen L, Mejia NI. Nat Rev Neurol. 2021 Jan 7:1-2. doi: 10.1038/s41582-020-00452-x.


Tractography-Pathology Correlations in Traumatic Brain Injury: A TRACK-TBI Study.
Nolan AL, Petersen C, Iacono D, Mac Donald CL, Mukherjee P, van der Kouwe A, Jain S, Stevens A, Diamond B, Wang R, Markowitz AJ, Fischl B, Perl D, Manley GT, Keene CD, Diaz-Arrastia R, Edlow BL. J Neurotrauma. 2021 Jan 7. doi: 10.1089/neu.2020.7373.


Case 26-2020: A Woman with Altered Mental Status and Left-Sided Weakness. Reply.
Singhal AB, Mukerji SS, Chwalisz BK. N Engl J Med. 2021 Jan 7;384(1):92. doi: 10.1056/NEJMc2030849.


Association of CSF Biomarkers with Hippocampal-dependent Memory in Preclinical Alzheimer Disease.
Trelle AN, Carr VA, Wilson EN, Swarovski MS, Hunt MP, Toueg TN, Tran TT, Channappa D, Corso NK, Thieu MK, Jayakumar M, Nadiadwala A, Guo W, Tanner NJ, Bernstein JD, Litovsky CP, Guerin SA, Khazenzon AM, Harrison MB, Rutt BK, Deutsch GK, Chin FT, Davidzon GA, Hall JN, Sha SJ, Fredericks CA, Andreasson KI, Kerchner GA, Wagner AD, Mormino EC. Neurology. 2021 Jan 6:10.1212/WNL.0000000000011477. doi: 10.1212/WNL.0000000000011477.


Beyond gait and balance: urinary and bowel dysfunction in X-linked adrenoleukodystrophy.
Corre CS, Grant N, Sadjadi R, Hayden D, Becker C, Gomery P, Eichler FS. Orphanet J Rare Dis. 2021 Jan 6;16(1):14. doi: 10.1186/s13023-020-01596-1.


Diminished Learning Over Repeated Exposures (LORE) in preclinical Alzheimer's disease.
Samaroo A, Amariglio RE, Burnham S, Sparks P, Properzi M, Schultz AP, Buckley R, Johnson KA, Sperling RA, Rentz DM, Papp KV. Alzheimers Dement (Amst). 2021 Jan 5;12(1):e12132. doi: 10.1002/dad2.12132. eCollection 2020.


MRI Characteristics of NMO, MOG and MS Related Optic Neuritis.
Winter A, Chwalisz B. Semin Ophthalmol. 2021 Jan 4:1-10. doi: 10.1080/08820538.2020.1866027. 


Neuroimaging in Frontotemporal Lobar Degeneration: Research and Clinical Utility.
Dev SI, Dickerson BC, Touroutoglou A. Adv Exp Med Biol. 2021;1281:93-112. doi: 10.1007/978-3-030-51140-1_7.


APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches.
Serrano-Pozo A, Das S, Hyman BT. Lancet Neurol. 2021 Jan;20(1):68-80. doi: 10.1016/S1474-4422(20)30412-9.


A Synergistic Engineering Approach to Build Human Brain Spheroids.
von Maydell D, Jorfi M. Methods Mol Biol. 2021;2258:151-169. doi: 10.1007/978-1-0716-1174-6_11. 


Huntington's Disease Pathogenesis: Two Sequential Components.
Hong EP, MacDonald ME, Wheeler VC, Jones L, Holmans P, Orth M, Monckton DG, Long JD, Kwak S, Gusella JF, Lee JM. J Huntingtons Dis. 2021;10(1):35-51. doi: 10.3233/JHD-200427.  


The role of biomarkers and neuroimaging in ischemic/hemorrhagic risk assessment for cardiovascular/cerebrovascular disease prevention.
Gokcal E, Horn MJ, Gurol ME. Handb Clin Neurol. 2021;177:345-357. doi: 10.1016/B978-0-12-819814-8.00021-4.


Modifiers of CAG/CTG Repeat Instability: Insights from Mammalian Models.
Wheeler VC, Dion V. J Huntingtons Dis. 2021;10(1):123-148. doi: 10.3233/JHD-200426.


Neuroimaging in Frontotemporal Lobar Degeneration: Research and Clinical Utility.
Dev SI, Dickerson BC, Touroutoglou A. Adv Exp Med Biol. 2021;1281:93-112. doi: 10.1007/978-3-030-51140-1_7.


The Computerized Cognitive Composite (C3) in an Alzheimer's Disease Secondary Prevention Trial.
Papp KV, Rentz DM, Maruff P, Sun CK, Raman R, Donohue MC, Schembri A, Stark C, Yassa MA, Wessels AM, Yaari R, Holdridge KC, Aisen PS, Sperling RA. J Prev Alzheimers Dis. 2021;8(1):59-67. doi: 10.14283/jpad.2020.38.


White Matter Acute Infarct Volume After Thrombectomy for Anterior Circulation Large Vessel Occlusion Stroke is Associated with Long Term Outcomes.
Regenhardt RW, Etherton MR, Das AS, Schirmer MD, Hirsch JA, Stapleton CJ, Patel AB, Leslie-Mazwi TM, Rost NS. J Stroke Cerebrovasc Dis. 2020 Dec 29;30(3):105567. doi: 10.1016/j.jstrokecerebrovasdis.2020.105567.


Financial Capacity and Regional Cerebral Tau in Cognitively Normal Older Adults, Mild Cognitive Impairment, and Alzheimer's Disease Dementia.
Gonzalez C, Tommasi NS, Briggs D, Properzi MJ, Amariglio RE, Marshall GA; Alzheimer’s Disease Neuroimaging Initiative. J Alzheimers Dis. 2020 Dec 29. doi: 10.3233/JAD-201122.


Tocilizumab in Covid-19. Reply.
Stone JH, Horick NK, Healy BC. N Engl J Med. 2020 Dec 22;384(1):10.1056/NEJMc2032911#sa2. doi: 10.1056/NEJMc2032911.


Advances in Stroke: Digital Health.
Silva GS, Schwamm LH. Stroke. 2021 Jan;52(1):351-355. doi: 10.1161/STROKEAHA.120.033239. Epub 2020 Dec 22.


Nelson Syndrome: Clival Invasion of Corticotroph Pituitary Adenoma Resulting in Alternating Sixth Nerve Palsies.
Douglas VP, Douglas KAA, Rapalino O, Champion SN, Chwalisz BK. J Neuroophthalmol. 2020 Dec 22;Publish Ahead of Print. doi: 10.1097/WNO.0000000000001141.


Impact of the COVID-19 Pandemic on Continuous EEG Utilization.
Zafar SF, Khozein RJ, LaRoche SM, Westover MB, Gilmore EJ. J Clin Neurophysiol. 2020 Dec 22;Publish Ahead of Print. doi: 10.1097/WNP.0000000000000802.


Fatal neurotoxicity after chimeric antigen receptor T-cell therapy: An unexpected case of fludarabine-associated progressive leukoencephalopathy.
Winter SF, Martinez-Lage M, Clement NF, Hochberg EP, Dietrich J. Eur J Cancer. 2020 Dec 22;144:178-181. doi: 10.1016/j.ejca.2020.11.021. 


The STARS Phase 2 Study: A Randomized Controlled Trial of Gaboxadol in Angelman Syndrome.
Bird LM, Ochoa-Lubinoff C, Tan WH, Heimer G, Melmed RD, Rakhit A, Visootsak J, During MJ, Holcroft C, Burdine RD, Kolevzon A, Thibert RL. Neurology. 2020 Dec 21:10.1212/WNL.0000000000011409. doi: 10.1212/WNL.0000000000011409.


Encephalitis and Meningitis in Western Africa: A Scoping Review of Pathogens.
Rezaei SJ, Mateen FJ. Trop Med Int Health. 2020 Dec 19. doi: 10.1111/tmi.13539.


Effects of Mexiletine on Hyperexcitability in Sporadic ALS: Preliminary Findings from A Small Phase II Randomized Controlled Trial.
Weiss MD, Macklin EA, McIlduff CE, Vucic S, Wainger BJ, Kiernan MC, Goutman SA, Goyal NA, Rutkove SB, Ladha SS, Amy Chen IH, Harms MB, Brannagan TH, Lacomis D, Zivkovic S, Ma M, Wang LH, Simmons Z, Rivner MH, Shefner JM, Cudkowicz ME, Atassi N; Mexiletine-2 ALS Study Group. Muscle Nerve. 2020 Dec 19. doi: 10.1002/mus.27146.


Saving cognitive outcome data in Alzheimer's disease clinical trials during the COVID-19 pandemic: Commentary on the virtual administration of the ADAS-Cog.
Schwab NA, DesRuisseaux LA, Weinberg MS, Arnold SE. Alzheimers Dement (N Y). 2020 Dec 16;6(1):e12081. doi: 10.1002/trc2.12081.


SVA insertion in X-linked Dystonia Parkinsonism alters histone H3 acetylation associated with TAF1 gene.
Petrozziello T, Dios AM, Mueller KA, Vaine CA, Hendriks WT, Glajch KE, Mills AN, Mangkalaphiban K, Penney EB, Ito N, Fernandez-Cerado C, Legarda GPA, Velasco-Andrada MS, Acuña PJ, Ang MA, Muñoz EL, Diesta CCE, Macalintal-Canlas R, Acuña G, Sharma N, Ozelius LJ, Bragg DC, Sadri-Vakili G. PLoS One. 2020 Dec 14;15(12):e0243655. doi: 10.1371/journal.pone.0243655. eCollection 2020.


Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies.
Edlow BL, Claassen J, Schiff ND, Greer DM. Nat Rev Neurol. 2020 Dec 14:1-22. doi: 10.1038/s41582-020-00428-x.


Patent Foramen Ovale Attributable Cryptogenic Embolism With Thrombophilia Has Higher Risk for Recurrence and Responds to Closure.
Liu K, Song B, Palacios IF, Inglessis-Azuaje I, Deng W, McMullin D, Wang X, Lo EH, Xu Y, Buonanno FS, Ning M. JACC Cardiovasc Interv. 2020 Dec 14;13(23):2745-2752. doi: 10.1016/j.jcin.2020.09.059.


High-throughput phenotyping with temporal sequences.
Estiri H, Strasser ZH, Murphy SN. J Am Med Inform Assoc. 2020 Dec 14:ocaa288. doi: 10.1093/jamia/ocaa288.


Dual hereditary and Immune-Mediated neuromuscular diagnoses after cancer immunotherapy.
Jiwa NS, Lawrence DP, Guidon AC. Muscle Nerve. 2020 Dec 13. doi: 10.1002/mus.27143.


Reply: Reference values for the Cerebellar Cognitive Affective Syndrome Scale: age and education matter.
Schmahmann JD, Vangel MG, Hoche F, Guell X, Sherman JC. Brain. 2020 Dec 13:awaa419. doi: 10.1093/brain/awaa419.


Classification of the Disposition of Patients Hospitalized with COVID-19: Reading Discharge Summaries using Natural Language Processing.
Fernandes M, Sun H, Jain A, Alabsi HS, Brenner LN, Ye E, Ge W, Collens SI, Leone M, Das S, Robbins GK, Mukerji SS, Westover MB. JMIR Med Inform. 2020 Dec 12. doi: 10.2196/25457.


A pilot protocol to assess the feasibility of a virtual multiple crossover, randomized controlled trial design using methylphenidate in mild cognitive impairment.
DesRuisseaux LA, Williams VJ, McManus AJ, Gupta AS, Carlyle BC, Azami H, Gerber JA, Bolling AM, Cook CL, Betensky RA, Arnold SE. Trials. 2020 Dec 11;21(1):1016. doi: 10.1186/s13063-020-04752-x.


Quantifying neurologic disease using biosensor measurements in-clinic and in free-living settings in multiple sclerosis.
Chitnis T, Glanz BI, Gonzalez C, Healy BC, Saraceno TJ, Sattarnezhad N, Diaz-Cruz C, Polgar-Turcsanyi M, Tummala S, Bakshi R, Bajaj VS, Ben-Shimol D, Bikhchandani N, Blocker AW, Burkart J, Cendrillon R, Cusack MP, Demiralp E, Jooste SK, Kharbouch A, Lee AA, Lehár J, Liu M, Mahadevan S, Murphy M, Norton LC, Parlikar TA, Pathak A, Shoeb A, Soderberg E, Stephens P, Stoertz AH, Thng F, Tumkur K, Wang H, Rhodes J, Rudick RA, Ransohoff RM, Phillips GA, Bruzik E, Marks WJ, Weiner HL, Snyder TM. NPJ Digit Med. 2019 Dec 11;2(1):123. doi: 10.1038/s41746-019-0197-7.


When real life conditions do not follow textbook diagnosis: A diagnostic challenge from a neuropsychiatric clinic.
Razafsha M, Buch K, Vitolo OV, Chemali Z. Int J Psychiatry Med. 2020 Dec 9:91217420979629. doi: 10.1177/0091217420979629.


Caregiver Satisfaction with a Video Telehealth Home Safety Evaluation for Dementia.
Gately ME, Tickle-Degnen L, Trudeau SA, Ward N, Ladin K, Moo LR. Int J Telerehabil. 2020 Dec 8;12(2):35-42. doi: 10.5195/ijt.2020.6337.


A Simplified Brain Blocking Protocol Optimized for the Diagnosis of Neurodegenerative Disease Saves Time and Money While Preserving Anatomic Relationships.
Clement NF, DeWitt JC, Frosch MP, Martinez-Lage M, Samore WR, Hedley-Whyte ET. Arch Pathol Lab Med. 2020 Dec 8. doi: 10.5858/arpa.2020-0322-OA.


Molecular imaging of Alzheimer's disease-related gamma-secretase in mice and nonhuman primates.
Xu Y, Wang C, Wey HY, Liang Y, Chen Z, Choi SH, Ran C, Rynearson KD, Bernales DR, Koegel RE, Fiedler SA, Striar R, Wagner SL, Tanzi RE, Zhang C. J Exp Med. 2020 Dec 7;217(12):e20182266. doi: 10.1084/jem.20182266.


Autobiography Series: A Half Century of Neuropathology.
Hedley-Whyte ET. J Neuropathol Exp Neurol. 2020 Dec 4;79(12):1385-1403. doi: 10.1093/jnen/nlaa135.


Sodium Phenylbutyrate-Taurursodiol for ALS. Reply.
Paganoni S, Cudkowicz ME. N Engl J Med. 2020 Dec 3;383(23):2294. doi: 10.1056/NEJMc2030710.


Neurophysiologic Mapping of Thalamocortical Tract in Asleep Craniotomies: Promising Results From an Early Experience.
Simon MV, Lee DK, Choi BD, Talati PA, Yang JC, Koch MJ, Jones PS, Curry WT. Oper Neurosurg (Hagerstown). 2020 Dec 2:opaa330. doi: 10.1093/ons/opaa330.


Public Health Responses to COVID-19: Whose Lives Do We Flatten Along With "The Curve?".
Ganesh A, Rato JM, Chennupati VM, Rojek A, Viswanathan A. Front Public Health. 2020 Dec 2;8:564111. doi: 10.3389/fpubh.2020.564111. eCollection 2020.


 Trajectory of Unawareness of Memory Decline in Individuals With Autosomal Dominant Alzheimer Disease.
Vannini P, Hanseeuw BJ, Gatchel JR, Sikkes SAM, Alzate D, Zuluaga Y, Moreno S, Mendez L, Baena A, Ospina-Lopera P, Tirado V, Henao E, Acosta-Baena N, Giraldo M, Lopera F, Quiroz YT. JAMA Netw Open. 2020 Dec 1;3(12):e2027472. doi: 10.1001/jamanetworkopen.2020.27472.


Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence.
Deng W, Yin S, McMullin D, Inglessis-Azuaje I, Elmariah S, Hung J, Lo EH, Palacios IF, Buonanno FS, Ning M. Ann Intern Med. 2020 Dec 1;173(11):946-947. doi: 10.7326/L20-1274.


Considering learning disabilities and attention-deficit hyperactivity disorder when assessing for neurodegenerative disease.
Colvin MK, Sherman JC. Neurol Clin Pract. 2020 Dec;10(6):520-526. doi: 10.1212/CPJ.0000000000000799.


Cautionary notes on diagnosing functional neurologic disorder as a neurologist-in-training.
Perez DL, Hunt A, Sharma N, Flaherty A, Caplan D, Schmahmann JD. Neurol Clin Pract. 2020 Dec;10(6):484-487. doi: 10.1212/CPJ.0000000000000779.


Palliative and Supportive Care in Neuro-oncology.
Forst DA. Continuum (Minneap Minn). 2020 Dec;26(6):1673-1685. doi: 10.1212/CON.0000000000000940.


Neurotoxicity of Cancer Therapies.
Dietrich J. Continuum (Minneap Minn). 2020 Dec;26(6):1646-1672. doi: 10.1212/CON.0000000000000943.


Stability of the timing of food intake at daily and monthly timescales in young adults.
McHill AW, Hilditch CJ, Fischer D, Czeisler CA, Garaulet M, Scheer FAJL, Klerman EB. Sci Rep. 2020 Nov 30;10(1):20849. doi: 10.1038/s41598-020-77851-z.


Classification of evoked responses to inverted faces reveals both spatial and temporal cortical response abnormalities in Autism spectrum disorder.
Nunes AS, Mamashli F, Kozhemiako N, Khan S, McGuiggan NM, Losh A, Joseph RM, Ahveninen J, Doesburg SM, Hämäläinen MS, Kenet T. Neuroimage Clin. 2020 Nov 30;29:102501. doi: 10.1016/j.nicl.2020.102501.


A practical approach to the management of cerebral amyloid angiopathy.
Kozberg MG, Perosa V, Gurol ME, van Veluw SJ. Int J Stroke. 2020 Nov 29:1747493020974464. doi: 10.1177/1747493020974464.


Isolated Cervical Dystonia: Management and Barriers to Care.
Supnet ML, Acuna P, Carr SJ, Kristoper de Guzman J, Al Qahtani X, Multhaupt-Buell T, Francoeur T, Aldykiewicz GE, Alluri PR, Campion L, Paul L, Ozelius L, Penney EB, Stephen CD, Dy-Hollins M, Sharma N. Front Neurol. 2020 Nov 27;11:591418. doi: 10.3389/fneur.2020.591418.


Isolated dystonia: clinical and genetic updates.
Domingo A, Yadav R, Ozelius LJ. J Neural Transm (Vienna). 2020 Nov 27. doi: 10.1007/s00702-020-02268-x.


Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals.
Chhatwal JP, Schultz AP, Dang Y, Ostaszewski B, Liu L, Yang HS, Johnson KA, Sperling RA, Selkoe DJ. Nat Commun. 2020 Nov 27;11(1):6024. doi: 10.1038/s41467-020-19543-w.


Vascular dysfunction promotes regional hypoxia after bevacizumab therapy in recurrent glioblastoma patients.
Gerstner ER, Emblem KE, Yen YF, Dietrich J, Jordan JT, Catana C, Wenchin KL, Hooker JM, Duda DG, Rosen BR, Kalpathy-Cramer J, Jain RK, Batchelor TT. Neurooncol Adv. 2020 Nov 17;2(1):vdaa157. doi: 10.1093/noajnl/vdaa157. eCollection 2020 Jan-Dec. 


Antisense oligonucleotide and adjuvant exercise therapy reverse fatigue in old mice with myotonic dystrophy.
Hu N, Kim E, Antoury L, Li J, González-Pérez P, Rutkove SB, Wheeler TM. Mol Ther Nucleic Acids. 2020 Nov 26;23:393-405. doi: 10.1016/j.omtn.2020.11.014. eCollection 2021 Mar 5.


Tauopathies: Deciphering Disease Mechanisms to Develop Effective Therapies.
Silva MC, Haggarty SJ. Int J Mol Sci. 2020 Nov 25;21(23):E8948. doi: 10.3390/ijms21238948.


Treatment Approaches and Outcomes for Acute Anterior Circulation Stroke Patients with Tandem Lesions
Neal M Nolan, Robert W Regenhardt, Matthew J Koch, Scott B Raymond, Christopher J Stapleton, James D Rabinov, Scott B Silverman, Thabele M Leslie-Mazwi, Aman B Patel. J Stroke Cerebrovasc Dis. 2020 Nov 25;30(2):105478. doi: 10.1016/j.jstrokecerebrovasdis.2020.105478.


What can we learn from brain autopsy in COVID-19?
Mukerji SS, Solomon IH. Neurosci Lett. 2020 Nov 25:135528. doi: 10.1016/j.neulet.2020.135528.


KCC2 chloride transport contributes to the termination of ictal epileptiform activity.
Dzhala VI, Staley KJ. eNeuro. 2020 Nov 24:ENEURO.0208-20.2020. doi: 10.1523/ENEURO.0208-20.2020.


Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.
Wainger BJ, Macklin EA, Vucic S, McIlduff CE, Paganoni S, Maragakis NJ, Bedlack R, Goyal NA, Rutkove SB, Lange DJ, Rivner MH, Goutman SA, Ladha SS, Mauricio EA, Baloh RH, Simmons Z, Pothier L, Kassis SB, La T, Hall M, Evora A, Klements D, Hurtado A, Pereira JD, Koh J, Celnik PA, Chaudhry V, Gable K, Juel VC, Phielipp N, Marei A, Rosenquist P, Meehan S, Oskarsson B, Lewis RA, Kaur D, Kiskinis E, Woolf CJ, Eggan K, Weiss MD, Berry JD, David WS, Davila-Perez P, Camprodon JA, Pascual-Leone A, Kiernan MC, Shefner JM, Atassi N, Cudkowicz ME. JAMA Neurol. 2020 Nov 23. doi: 10.1001/jamaneurol.2020.4300.


Seeking Clarity About Confusion.
Sherer M, Katz DI, Bodien YG. Arch Phys Med Rehabil. 2020 Nov 21:S0003-9993(20)31160-6. doi: 10.1016/j.apmr.2020.10.111.


Author Correction: Ensemble learning predicts multiple sclerosis disease course in the SUMMIT study.
Zhao Y, Wang T, Bove R, Cree B, Henry R, Lokhande H, Polgar-Turcsanyi M, Anderson M, Bakshi R, Weiner HL, Chitnis T; SUMMIT Investigators. NPJ Digit Med. 2020 Nov 20;3(1):155. doi: 10.1038/s41746-020-00361-9. PMID: 33299133


Therapeutic Strategies to Target Calcium Dysregulation in Alzheimer's Disease.
Calvo-Rodriguez M, Kharitonova EK, Bacskai BJ. Cells. 2020 Nov 20;9(11):2513. doi: 10.3390/cells9112513.


Ascending arousal network connectivity during recovery from traumatic coma.
Snider SB, Bodien YG, Frau-Pascual A, Bianciardi M, Foulkes AS, Edlow BL. Neuroimage Clin. 2020;28:102503. doi: 10.1016/j.nicl.2020.102503. Epub 2020 Nov 19.


Trappc9 deficiency in mice impairs learning and memory by causing imbalance of dopamine D1 and D2 neurons.
Ke Y, Weng M, Chhetri G, Usman M, Li Y, Yu Q, Ding Y, Wang Z, Wang X, Sultana P, DiFiglia M, Li X. Sci Adv. 2020 Nov 18;6(47):eabb7781. doi: 10.1126/sciadv.abb7781.


Predicting treatment outcomes for bilinguals with aphasia using computational modeling: Study protocol for the PROCoM randomised controlled trial.
Peñaloza C, Dekhtyar M, Scimeca M, Carpenter E, Mukadam N, Kiran S. BMJ Open. 2020 Nov 18;10(11):e040495. doi: 10.1136/bmjopen-2020-040495.


Approaches to Disease Modification for Parkinson's Disease: Clinical Trials and Lessons Learned.
Hung AY, Schwarzschild MA. Neurotherapeutics. 2020 Nov 17. doi: 10.1007/s13311-020-00964-w.


Not All Lobar Hemorrhages Are Created Equal.
Das AS, Gurol ME. Stroke. 2020 Nov 17:STROKEAHA120032404. doi: 10.1161/STROKEAHA.120.032404.


A pilot randomized, controlled, double-blind trial of bumetanide to treat neonatal seizures
Soul JS, Bergin AM, Stopp C, Hayes B, Singh A, Fortuno CR, O'Reilly D, Krishnamoorthy K, Jensen FE, Rofeberg V, Dong M, Vinks AA, Wypij D, Staley KJ; Boston Bumetanide Trial Group. Ann Neurol. 2020 Nov 17. doi: 10.1002/ana.25959. 


Cerebrovascular disease progression in patients with ACTA2 Arg179 Pathogenic Variants.
Lauer A, Speroni SL, Patel JB, Regalado E, Choi M, Smith E, Kalpathy-Kramer J, Caruso P, Milewicz DM, Musolino PL. Neurology. 2020 Nov 16:10.1212/WNL.0000000000011210. doi: 10.1212/WNL.0000000000011210.


Case 35-2020: A 59-Year-Old Woman with Type 1 Diabetes Mellitus and Obtundation.
Caplan DN, Rapalino O, Karaa A, Rosovsky RP, Uljon S. N Engl J Med. 2020 Nov 12;383(20):1974-1983. doi: 10.1056/NEJMcpc2002412.


Versatile Role of Rab27a in Glioma: Effects on Release of Extracellular Vesicles, Cell Viability, and Tumor Progression.
van Solinge TS, Abels ER, van de Haar LL, Hanlon KS, Maas SLN, Schnoor R, de Vrij J, Breakefield XO, Broekman MLD. Front Mol Biosci. 2020 Nov 12;7:554649. doi: 10.3389/fmolb.2020.554649. eCollection 2020.


Altered functional connectivity of cortical networks in semantic variant Primary Progressive Aphasia.
Popal H, Quimby M, Hochberg D, Dickerson BC, Collins JA. Neuroimage Clin. 2020;28:102494. doi: 10.1016/j.nicl.2020.102494. Epub 2020 Nov 11.


Reply: No grey matter alterations in longitudinal data of migraine patients.
Burke MJ, Fox MD. Brain. 2020 Nov 11:awaa301. doi: 10.1093/brain/awaa301.


Prevalence, severity, and associations of depression in people with epilepsy in Guinea: A single-center study.
Sylla M, Vogel AC, Bah AK, Tassiou NR, Barry SD, Djibo BA, Toure ML, Foksona S, Konate M, Cisse FA, Mateen FJ. Epilepsy Behav. 2020 Nov 11;113:107475. doi: 10.1016/j.yebeh.2020.107475.


Delayed reemergence of consciousness in survivors of severe COVID-19
Edlow BL, Claassen J, Victor JD, Brown EN, Schiff ND. Neurocrit Care. 2020 Nov 10. doi: 10.1007/s12028-020-01133-9.


New therapies for neuromyelitis optica spectrum disorder
Levy M, Fujihara K, Palace J. Lancet Neurology. 2020 Nov 10. DOI: https://doi.org/10.1016/S1474-4422(20)30392-6


Eastern equine encephalitis and use of IV immunoglobulin therapy and high-dose steroids
Wilcox DR, Collens SI, Solomon IH, Mateen FJ, Mukerji SS. Neurol Neuroimmunol Neuroinflamm. 2020 Nov 10;8(1):e917. doi: 10.1212/NXI.0000000000000917.


Implications of new genetic risk factors in prion disease
Vallabh SM, Minikel EV. Nat Rev Neurol. 2020 Nov 10. doi: 10.1038/s41582-020-00433-0.


Time-dependent, dynamic prediction of fatty acid-binding protein 4, Galectin-3, and soluble ST2 measurement with poor outcome after acute stroke.
Hansen C, Sastre C, Wolcott Z, Bevers MB, Kimberly WT. Int J Stroke. 2020 Nov 9:1747493020971166. doi: 10.1177/1747493020971166.


Alzheimer-related altered white matter microstructural integrity in Down syndrome: A model for sporadic AD?
Rosas HD, Hsu E, Mercaldo ND, Lai F, Pulsifer M, Keator D, Brickman AM, Price J, Yassa M, Hom C, Krinsky-McHale SJ, Silverman W, Lott I, Schupf N. Alzheimers Dement (Amst). 2020 Nov 7;12(1):e12040. doi: 10.1002/dad2.12040. eCollection 2020


Orally Administered 5-aminolevulinic Acid for Isolation and Characterization of Circulating Tumor-Derived Extracellular Vesicles in Glioblastoma Patients.
Maas SLN, van Solinge TS, Schnoor R, Yekula A, Senders JT, de Vrij J, Robe P, Carter BS, Balaj L, Arkesteijn GJA, Nolte-'t Hoen ENM, Broekman MLD. Cancers (Basel). 2020 Nov 7;12(11):E3297. doi: 10.3390/cancers12113297. 


Survival prediction of glioblastoma patients-are we there yet? A systematic review of prognostic modeling for glioblastoma and its clinical potential.
Tewarie IA, Senders JT, Kremer S, Devi S, Gormley WB, Arnaout O, Smith TR, Broekman MLD. Neurosurg Rev. 2020 Nov 6. doi: 10.1007/s10143-020-01430-z.


Dual-Task Gait Stability after Concussion and Subsequent Injury: An Exploratory Investigation.
Howell DR, Bonnette S, Diekfuss JA, Grooms DR, Myer GD, Wilson JC, Meehan WP 3rd. Sensors (Basel). 2020 Nov 5;20(21):E6297. doi: 10.3390/s20216297. 


Antibody Testing in Atypical Optic Neuritis.
Truong-Le M, Chwalisz B. Semin Ophthalmol. 2020 Nov 5:1-9. doi: 10.1080/08820538.2020.1820047.


Clostridium bolteae is elevated in neuromyelitis optica spectrum disorder in India and shares sequence similarity with AQP4.
Pandit L, Cox LM, Malli C, D'Cunha A, Rooney T, Lokhande H, Willocq V, Saxena S, Chitnis T. Neurol Neuroimmunol Neuroinflamm. 2020 Nov 4;8(1):e907. doi: 10.1212/NXI.0000000000000907.


Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.
Prokopenko D, Morgan SL, Mullin K, Hofmann O, Chapman B, Kirchner R, Amberkar S, Wohlers I, Lange C, Hide W, Bertram L, Tanzi RE. medRxiv. 2020 Nov 4:2020.11.03.20225540. doi: 10.1101/2020.11.03.20225540.  


Mitochondria and Calcium in Alzheimer's Disease: From Cell Signaling to Neuronal Cell Death.
Calvo-Rodriguez M, Bacskai BJ. Trends Neurosci. 2020 Nov 4:S0166-2236(20)30224-1. doi: 10.1016/j.tins.2020.10.004.


Rodent Models of Optic Neuritis.
Redler Y, Levy M. Front Neurol. 2020 Nov 3;11:580951. doi: 10.3389/fneur.2020.580951. eCollection 2020.


Language preference does not influence stroke patients' symptom recognition or emergency care time metrics.
Zachrison KS, Natsui S, Luan Erfe BM, Mejia NI, Schwamm LH. Am J Emerg Med. 2020 Nov 2:S0735-6757(20)30962-1. doi: 10.1016/j.ajem.2020.10.064.


The human gut microbiota in people with amyotrophic lateral sclerosis.
Nicholson K, Bjornevik K, Abu-Ali G, Chan J, Cortese M, Dedi B, Jeon M, Xavier R, Huttenhower C, Ascherio A, Berry JD. Amyotroph Lateral Scler Frontotemporal Degener. 2020 Nov 2:1-9. doi: 10.1080/21678421.2020.1828475.


Delirium in Older Patients With COVID-19 Presenting to the Emergency Department.
Kennedy M, Helfand BKI, Gou RY, Gartaganis SL, Webb M, Moccia JM, Bruursema SN, Dokic B, McCulloch B, Ring H, Margolin JD, Zhang E, Anderson R, Babine RL, Hshieh T, Wong AH, Taylor RA, Davenport K, Teresi B, Fong TG, Inouye SK. JAMA Netw Open. 2020 Nov 2;3(11):e2029540. doi: 10.1001/jamanetworkopen.2020.29540.


Quantity, Content, and Context Matter: Associations Among Social Technology Use and Sleep Habits in Early Adolescents.
Charmaraman L, Richer AM, Ben-Joseph EP, Klerman EB. J Adolesc Health. 2020 Nov 1:S1054-139X(20)30588-7. doi: 10.1016/j.jadohealth.2020.09.035.


Subdural Hematoma: Predictors of Outcome and a Score to Guide Surgical Decision-Making.
Sharma R, Rocha E, Pasi M, Lee H, Patel A, Singhal AB. J Stroke Cerebrovasc Dis. 2020 Nov;29(11):105180. doi: 10.1016/j.jstrokecerebrovasdis.2020.105180.


Clinical significance of angiotensin-converting enzyme 2 receptors for severe acute respiratory syndrome coronavirus 2 (COVID-19) on peripheral small-fiber sensory neurons is unknown today.
Oaklander AL.
Pain. 2020 Nov;161(11):2431-2433. doi: 10.1097/j.pain.0000000000002050.


The ethical and legal status of neurosurgical guidelines: the neurosurgeon's golden fleece or Achilles' heel?
Tewarie IA, Hulsbergen AFC, Volovici V, Broekman MLD. Neurosurg Focus. 2020 Nov;49(5):E14. doi: 10.3171/2020.8.FOCUS20597.


Toward a Personalized Approach to Parkinson's Cell Therapy.
Herrington TM, Schweitzer J, Henchcliffe C, Carter BS, Kim KS. Mov Disord. 2020 Nov;35(11):2119-2120. doi: 10.1002/mds.28328.


Sunflower syndrome: a poorly understood photosensitive epilepsy.
Geenen KR, Patel S, Thiele EA. Dev Med Child Neurol. 2020 Oct 31. doi: 10.1111/dmcn.14723. 


Instrumental activities of daily living, amyloid, and cognition in cognitively normal older adults screening for the A4 Study.
Marshall GA, Sikkes SAM, Amariglio RE, Gatchel JR, Rentz DM, Johnson KA, Langford O, Sun CK, Donohue MC, Raman R, Aisen PS, Sperling RA, Galasko DR; Full listing of A4 Study team and site personnel available at A4STUDY.org. Alzheimers Dement (Amst). 2020 Oct 30;12(1):e12118. doi: 10.1002/dad2.12118. eCollection 2020.


Toward a more inclusive paradigm: thrombectomy for stroke patients with pre-existing disabilities.
Regenhardt RW, Young MJ, Etherton MR, Das AS, Stapleton CJ, Patel AB, Lev MH, Hirsch JA, Rost NS, Leslie-Mazwi TM. J Neurointerv Surg. 2020 Oct 30:neurintsurg-2020-016783. doi: 10.1136/neurintsurg-2020-016783.


Accurate detection of cerebellar smooth pursuit eye movement abnormalities via mobile phone video and machine learning.
Chang Z, Chen Z, Stephen CD, Schmahmann JD, Wu HT, Sapiro G, Gupta AS. Sci Rep. 2020 Oct 29;10(1):18641. doi: 10.1038/s41598-020-75661-x.


Infarct Growth despite Endovascular Thrombectomy Recanalization in Large Vessel Occlusive Stroke.
Regenhardt RW, Etherton MR, Das AS, Schirmer MD, Hirsch JA, Stapleton CJ, Patel AB, Leslie-Mazwi TM, Rost NS. J Neuroimaging. 2020 Oct 29. doi: 10.1111/jon.12796.


Smartphone data during the COVID-19 pandemic can quantify behavioral changes in people with ALS.
Beukenhorst AL, Collins E, Burke KM, Rahman SM, Clapp M, Konanki SC, Paganoni S, Miller TM, Chan J, Onnela JP, Berry JD. Muscle Nerve. 2020 Oct 29. doi: 10.1002/mus.27110.


Night-to-night variability of sleep electroencephalography-based brain age measurements.
Hogan J, Sun H, Paixao L, Westmeijer M, Sikka P, Jin J, Tesh R, Cardoso M, Cash SS, Akeju O, Thomas R, Westover MB. Clin Neurophysiol. 2020 Oct 29;132(1):1-12. doi: 10.1016/j.clinph.2020.09.029.


Corrigendum to: Recycling drug screen repurposes hydroxyurea as a sensitizer of glioblastomas to temozolomide targeting de novo DNA synthesis, irrespective of molecular subtype.
Teng J, Hejazi S, Hiddingh L, Carvalho L, de Gooijer M, Wakimoto H, Barazas M, Tannous M, Chi AS, Noske DP, Wesseling P, Wurdinger T, Batchelor TT, Tannous BA. Neuro Oncol. 2020 Oct 28:noaa166. doi: 10.1093/neuonc/noaa166.


Intravascular Endothelin-1 does not trigger or increase susceptibility to Spreading Depolarizations.
Sugimoto K, Morais A, Sadeghian H, Qin T, Chung DY, Ashina M, Hougaard A, Ayata C. J Headache Pain. 2020 Oct 27;21(1):127. doi: 10.1186/s10194-020-01194-3.


White Matter Hyperintensity Burden Is Associated With Hippocampal Subfield Volume in Stroke.
Etherton MR, Fotiadis P, Giese AK, Iglesias JE, Wu O, Rost NS. Front Neurol. 2020 Oct 26;11:588883. doi: 10.3389/fneur.2020.588883. eCollection 2020.


Association of dilated perivascular spaces and disease severity in patients with Huntington's disease.
Chan ST, Mercaldo ND, Ravina B, Hersch SM, Rosas HD. Neurology. 2020 Oct 26:10.1212/WNL.0000000000011121. doi: 10.1212/WNL.0000000000011121.


Assessment of Emergency Department and Inpatient Use and Costs in Adult and Pediatric Functional Neurological Disorders.
Stephen CD, Fung V, Lungu CI, Espay AJ. JAMA Neurol. 2020 Oct 26. doi: 10.1001/jamaneurol.2020.3753.

CoVA: An Acuity Score for Outpatient Screening that Predicts COVID-19 Prognosis.
Sun H, Jain A, Leone MJ, Alabsi HS, Brenner LN, Ye E, Ge W, Shao YP, Boutros CL, Wang R, Tesh RA, Magdamo C, Collens SI, Ganglberger W, Bassett IV, Meigs JB, Kalpathy-Cramer J, Li MD, Chu JT, Dougan ML, Stratton LW, Rosand J, Fischl B, Das S, Mukerji SS, Robbins GK, Westover MB. J Infect Dis. 2020 Oct 24:jiaa663. doi: 10.1093/infdis/jiaa663.


Rapid annotation of seizures and interictal-ictal-injury continuum EEG patterns.
Jing J, d'Angremont E, Ebrahim S, Tabaeizadeh M, Ng M, Herlopian A, Dauwels J, Westover MB. J Neurosci Methods. 2020 Oct 22:108966. doi: 10.1016/j.jneumeth.2020.108966.


CT-visible convexity subarachnoid hemorrhage is associated with cortical superficial siderosis and predicts recurrent ICH.
Li Q, Zanon Zotin MC, Warren AD, Ma Y, Gurol E, Goldstein JN, Greenberg SM, Charidimou A, Raposo N, Viswanathan A. Neurology. 2020 Oct 21:10.1212/WNL.0000000000011052. doi: 10.1212/WNL.0000000000011052.


Night Watch on the Titanic: Detecting Early Signs of Epileptogenesis in Alzheimer Disease. Lam AD, Noebels J. Epilepsy Curr. 2020 Oct 20:1535759720964775. doi: 10.1177/1535759720964775.


Synaptic and metabolic gene expression alterations in neurons that are recipients of proteopathic tau seeds.
Perez-Rando M, Dujardin S, Bennett RE, Commins C, Nibhanupudy T, Hyman BT. Acta Neuropathol Commun. 2020 Oct 19;8(1):168. doi: 10.1186/s40478-020-01049-7.


Long-Term Survival of Participants in the CENTAUR Trial of Sodium Phenylbutyrate-Taurursodiol in ALS.
Paganoni S, Hendrix S, Dickson SP, Knowlton N, Macklin EA, Berry JD, Elliott MA, Maiser S, Karam C, Caress JB, Owegi MA, Quick A, Wymer J, Goutman SA, Heitzman D, Heiman-Patterson TD, Jackson CE, Quinn C, Rothstein JD, Kasarskis EJ, Katz J, Jenkins L, Ladha S, Miller TM, Scelsa SN, Vu TH, Fournier CN, Glass JD, Johnson KM, Swenson A, Goyal NA, Pattee GL, Andres PL, Babu S, Chase M, Dagostino D, Hall M, Kittle G, Eydinov M, McGovern M, Ostrow J, Pothier L, Randall R, Shefner JM, Sherman AV, St Pierre ME, Tustison E, Vigneswaran P, Walker J, Yu H, Chan J, Wittes J, Yu ZF, Cohen J, Klee J, Leslie K, Tanzi RE, Gilbert W, Yeramian PD, Schoenfeld D, Cudkowicz ME. Muscle Nerve. 2020 Oct 16. doi: 10.1002/mus.27091.

Ensemble learning predicts multiple sclerosis disease course in the SUMMIT study.
Zhao Y, Wang T, Bove R, Cree B, Henry R, Lokhande H, Polgar-Turcsanyi M, Anderson M, Bakshi R, Weiner HL, Chitnis T; SUMMIT Investigators. NPJ Digit Med. 2020 Oct 16;3:135. doi: 10.1038/s41746-020-00338-8. eCollection 2020.


Association of cerebral small vessel disease and cognitive decline after intracerebral hemorrhage.
Pasi M, Sugita L, Xiong L, Charidimou A, Boulouis G, Pongpitakmetha T, Singh S, Kourkoulis C, Schwab K, Greenberg SM, Anderson CD, Gurol ME, Rosand J, Viswanathan A, Biffi A. Neurology. 2020 Oct 16:10.1212/WNL.0000000000011050. doi: 10.1212/WNL.0000000000011050.


Case 32-2020: A 63-Year-Old Man with Confusion, Fatigue, and Garbled Speech.
Mukerji SS, Ard KL, Schaefer PW, Branda JA. N Engl J Med. 2020 Oct 15;383(16):1578-1586. doi: 10.1056/NEJMcpc2004996.


Purifying Selection against Pathogenic Mitochondrial DNA in Human T Cells.
Walker MA, Lareau CA, Ludwig LS, Karaa A, Sankaran VG, Regev A, Mootha VK. N Engl J Med. 2020 Oct 15;383(16):1556-1563. doi: 10.1056/NEJMoa2001265.


Algorithm for automatic detection of self-similarity and prediction of residual central respiratory events during CPAP.
Oppersma E, Ganglberger W, Sun H, Thomas RJ, Westover MB. Sleep. 2020 Oct 15:zsaa215. doi: 10.1093/sleep/zsaa215.


OpBox: Open source tools for simultaneous EEG and EMG acquisition from multiple subjects.
Kimchi EY, Coughlin BF, Shanahan BE, Piantoni G, Pezaris J, Cash SS. eNeuro. 2020 Oct 15:ENEURO.0212-20.2020. doi: 10.1523/ENEURO.0212-20.2020.

Cell type-specific lipid storage changes in Parkinson's disease patient brains are recapitulated by experimental glycolipid disturbance.
Brekk OR, Honey JR, Lee S, Hallett PJ, Isacson O. Proc Natl Acad Sci U S A. 2020 Oct 15:202003021. doi: 10.1073/pnas.2003021117.

Ictal EEG in sunflower syndrome: Provoked or unprovoked seizures?
Sourbron J, Ayub N, Luo Y, Thiele EA. Epilepsy Behav. 2020 Oct 15;113:107470. doi: 10.1016/j.yebeh.2020.107470.


Segmental Myoclonus Following Hepatorenal Transplant and Tacrolimus Immunosuppression.
McLaughlin AM, Khan TR, Lauritsen J, Batley K, Waugh JL. Pediatr Neurol. 2020 Oct 14;114:40-41. doi: 10.1016/j.pediatrneurol.2020.09.008.


Paroxysmal symptoms in neuromyelitis optica spectrum disorder: Results from an online patient survey.
Lotan I, Bacon T, Kister I, Levy M. Mult Scler Relat Disord. 2020 Oct 13;46:102578. doi: 10.1016/j.msard.2020.102578.


Identifying Sensitive Measures of Cognitive Decline at Different Clinical Stages of Alzheimer's Disease.
Jutten RJ, Sikkes SAM, Amariglio RE, Buckley RF, Properzi MJ, Marshall GA, Rentz DM, Johnson KA, Teunissen CE, Van Berckel BNM, Van der Flier WM, Scheltens P, Sperling RA, Papp KV; Alzheimer Disease Neuroimaging Initiative; National Alzheimer’s Coordinating Center, the Harvard Aging Brain Study, and the Alzheimer Dementia Cohort.
J Int Neuropsychol Soc. 2020 Oct 13:1-13. doi: 10.1017/S1355617720000934. 


Generative transfer learning for measuring plausibility of EHR diagnosis records.
Estiri H, Vasey S, Murphy SN. J Am Med Inform Assoc. 2020 Oct 12:ocaa215. doi: 10.1093/jamia/ocaa215.


Psychometric longitudinal evaluation of the Chronic Acquired Polyneuropathy Patient-Reported Index (CAPPRI) in patients with Chronic Inflammatory Demyelinating Polyneuropathy.
Sadjadi R, Peric S, Gwathmey K, Bozovic I, Aleksa P, Bjelica B, Burns T, Basta I. Muscle Nerve. 2020 Oct 11. doi: 10.1002/mus.27089.


MRI in disorders of consciousness.
Snider SB, Edlow BL. Curr Opin Neurol. 2020 Oct 9. doi: 10.1097/WCO.0000000000000873.


Optogenetic spreading depression elicits trigeminal pain and anxiety behavior.
Harriott AM, Chung DY, Uner A, Bozdayi RO, Morais A, Takizawa T, Qin T, Ayata C. Ann Neurol. 2020 Oct 5. doi: 10.1002/ana.25926.


Patterns of anticonvulsant use and adverse drug events in older adults.
Moura LMVR, Smith JR, Yan Z, Blacker D, Schwamm LH, Newhouse JP, Hernandez-Diaz S, Hsu J. Pharmacoepidemiol Drug Saf. 2020 Oct 2. doi: 10.1002/pds.5139. 


Hemorrhagic Papilledema Secondary to Craniopharyngioma.
Douglas VP, Douglas KAA, Chwalisz BK. JAMA Ophthalmol. 2020 Oct 1;138(10):e200880. doi: 10.1001/jamaophthalmol.2020.0880.


Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns.
Asher DM, Belay E, Bigio E, Brandner S, Brubaker SA, Caughey B, Clark B, Damon I, Diamond M, Freund M, Hyman BT, Jucker M, Keene CD, Lieberman AP, Mackiewicz M, Montine TJ, Morgello S, Phelps C, Safar J, Schneider JA, Schonberger LB, Sigurdson C, Silverberg N, Trojanowski JQ, Frosch MP. J Neuropathol Exp Neurol. 2020 Oct 1:nlaa109. doi: 10.1093/jnen/nlaa109.


Approaches to Optimize Medication Data Analysis in Clinical Cohort Studies.
Duprey MS, Devlin JW, Briesacher BA, Travison TG, Griffith JL, Inouye SK. J Am Geriatr Soc. 2020 Oct 1. doi: 10.1111/jgs.16844.


Is the incidence of multiple sclerosis really increasing?
Hawkes CH, Giovannoni G, Lechner-Scott J, Levy M. Mult Scler Relat Disord. 2020 Oct;45:102527. doi: 10.1016/j.msard.2020.102527. Epub 2020 Sep 30.


Cryptogenic stroke: Contemporary trends, treatments, and outcomes in the United States.
Prabhakaran S, Messé SR, Kleindorfer D, Smith EE, Fonarow GC, Xu H, Zhao X, Lytle B, Cigarroa J, Schwamm LH. Neurol Clin Pract. 2020 Oct;10(5):396-405. doi: 10.1212/CPJ.0000000000000736.


If LRRK2 Set the Fire, Can Nonsteroidal Anti-inflammatory Drugs Wet the Flames?
Crotty GF, Lo RY, Schwarzschild MA. Mov Disord. 2020 Oct;35(10):1727-1730. doi: 10.1002/mds.28240.


Association of caffeine and related analytes with resistance to Parkinson's disease among LRRK2 mutation carriers: A metabolomic study.
Crotty GF, Maciuca R, Macklin EA, Wang J, Montalban M, Davis SS, Alkabsh JI, Bakshi R, Chen X, Ascherio A, Astarita G, Huntwork-Rodriguez S, Schwarzschild MA. Neurology. 2020 Sep 30:10.1212/WNL.0000000000010863. doi: 10.1212/WNL.0000000000010863.


Mesenchymal Transformation: The Rosetta Stone of Glioblastoma Pathogenesis and Therapy Resistance.
Azam Z, To ST, Tannous BA. Adv Sci (Weinh). 2020 Sep 28;7(22):2002015. doi: 10.1002/advs.202002015.


Reply to: Cluster headache by orbital myositis. Comment: Orbital myositis triggering oxygen-responsive cluster headache.
Douglas VP, Douglas KAA, Rizzo JF 3rd, Chwalisz BK. Cephalalgia. 2020 Sep 26:333102420961561. doi: 10.1177/0333102420961561.


Characterizing Clinical and Neuropathological Traits of APOE Haplotypes in African Americans and Europeans. Mezlini AM, Magdamo C, Merrill E, Chibnik LB, Blacker DL, Hyman BT, Das S. J Alzheimers Dis. 2020 Sep 25. doi: 10.3233/JAD-200228.


TAF1 Transcripts and Neurofilament Light Chain as Biomarkers for X-Linked Dystonia-Parkinsonism.
Al Ali J, Vaine CA, Shah S, Campion L, Hakoum A, Supnet ML, Acuña P, Aldykiewicz G, Multhaupt-Buell T, Ganza NGM, Lagarde JBB, De Guzman JK, Go C, Currall B, Trombetta B, Webb PK, Talkowski M, Arnold SE, Cheah PS, Ito N, Sharma N, Bragg DC, Ozelius L, Breakefield XO. Mov Disord. 2020 Sep 25. doi: 10.1002/mds.28305.


The Forest and the Trees.
Leslie-Mazwi TM, Hirsch JA. AJNR Am J Neuroradiol. 2020 Sep 24. doi: 10.3174/ajnr.A6864. 


3D Exploration of the Brainstem in 50-Micron Resolution MRI.
Rushmore RJ, Wilson-Braun P, Papadimitriou G, Ng I, Rathi Y, Zhang F, O'Donnell LJ, Kubicki M, Bouix S, Yeterian E, Lemaire JJ, Calabrese E, Johnson GA, Kikinis R, Makris N. Front Neuroanat. 2020 Sep 23;14:40. doi: 10.3389/fnana.2020.00040.


MRI-based Parcellation and Morphometry of the Individual Rhesus Monkey Brain: the macaque Harvard-Oxford Atlas (mHOA), a translational system referencing a standardized ontology.
Rushmore RJ, Bouix S, Kubicki M, Rathi Y, Rosene DL, Yeterian EH, Makris N. Brain Imaging Behav. 2020 Sep 22. doi: 10.1007/s11682-020-00357-9.


Trends in Reperfusion Therapy for In-Hospital Ischemic Stroke in the Endovascular Therapy Era.
Akbik F, Xu H, Xian Y, Shah S, Smith EE, Bhatt DL, Matsouaka RA, Fonarow GC, Schwamm LH. JAMA Neurol. 2020 Sep 21. doi: 10.1001/jamaneurol.2020.3362.


Neuro-ophthalmic manifestations of Susac syndrome.
Redler Y, Chwalisz BK. Curr Opin Ophthalmol. 2020 Sep 21. doi: 10.1097/ICU.0000000000000713.


Neuro-ophthalmic manifestations of coronavirus disease 19.
Tisdale AK, Chwalisz B. Curr Opin Ophthalmol. 2020 Sep 21. doi: 10.1097/ICU.0000000000000707.


Impact of the COVID-19 pandemic on the health care of >1,000 People living with multiple sclerosis: A cross-sectional study.
Vogel AC, Schmidt H, Loud S, McBurney R, Mateen FJ. Mult Scler Relat Disord. 2020 Sep 19;46:102512. doi: 10.1016/j.msard.2020.102512.


The neurophysiology and seizure outcomes of late onset unexplained epilepsy.
Sarkis RA, Beers L, Farah E, Al-Akaidi M, Zhang Y, Locascio JJ, Properzi MJ, Schultz AP, Chhatwal JP, Johnson KA, Sperling RA, B Pennell P, Marshall GA. Clin Neurophysiol. 2020 Sep 18;131(11):2667-2672. doi: 10.1016/j.clinph.2020.08.014.  


Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease.
Bryant AG, Hu M, Carlyle BC, Arnold SE, Frosch MP, Das S, Hyman BT, Bennett RE. Front Neurol. 2020 Sep 16;11:575953. doi: 10.3389/fneur.2020.575953.


Social support in multiple sclerosis: Associations with quality of life, depression, and anxiety.
Ratajska A, Glanz BI, Chitnis T, Weiner HL, Healy BC. J Psychosom Res. 2020 Sep 16;138:110252. doi: 10.1016/j.jpsychores.2020.110252.


Comment on COVID-19 in patients with myasthenia gravis: Author response.
Anand P, Slama MCC, Kaku M, Ong C, Cervantes-Arslanian AM, Zhou L, David WS, Guidon AC. Muscle Nerve. 2020 Sep 16. doi: 10.1002/mus.27062.


Rapid hematoma growth triggers spreading depolarizations in experimental intracortical hemorrhage.
Fischer P, Sugimoto K, Chung DY, Tamim I, Morais A, Takizawa T, Qin T, Gomez CA, Schlunk F, Endres M, Yaseen MA, Sakadzic S, Ayata C. J Cereb Blood Flow Metab. 2020 Sep 16:271678X20951993. doi: 10.1177/0271678X20951993.


Subarachnoid hemorrhage leads to early and persistent functional connectivity and behavioral changes in mice.
Chung DY, Oka F, Jin G, Harriott A, Kura S, Aykan SA, Qin T, Iii WJE, Lee H, Yaseen MA, Sakadžić S, Boas DA, Whalen MJ, Ayata C. J Cereb Blood Flow Metab. 2020 Sep 16:271678X20940152. doi: 10.1177/0271678X20940152.


Neuropathological correlates of cortical superficial siderosis in cerebral amyloid angiopathy.
Charidimou A, Perosa V, Frosch MP, Scherlek AA, Greenberg SM, van Veluw SJ. Brain. 2020 Sep 16:awaa266. doi: 10.1093/brain/awaa266.


Editorial: Performance and Participation Outcomes for Individuals With Neurological Conditions.
Josman N, Connor LT, Lin DJ. Front Neurol. 2020 Sep 15;11:878. doi: 10.3389/fneur.2020.00878.


Home Video Visits: 2-D View of the Geriatric 5-Ms.
Moo LR. J Am Geriatr Soc. 2020 Sep 15. doi: 10.1111/jgs.16843.


MRI-visible Enlarged perivascular spaces: Beyond microbleeds to predict intracerebral hemorrhage.
Raposo N, Viswanathan A. Neurology. 2020 Sep 15:10.1212/WNL.0000000000010790. doi: 10.1212/WNL.0000000000010790. 


Long-term follow-up results of the SMART coil in the endovascular treatment of intracranial aneurysms.
McAvoy MB, Cappuzzo JM, Stapleton CJ, Koch MJ, Raymond SB, Torok CM, Patel AB. Interv Neuroradiol. 2020 Sep 15:1591019920956890. doi: 10.1177/1591019920956890.

MGMT promoter methylation and hypermutant recurrence in IDH mutant lower-grade glioma.
Miller JJ, Cahill DP. Neuro Oncol. 2020 Sep 14:noaa212. doi: 10.1093/neuonc/noaa212.


Sex differences in risk of Alzheimer's disease in adults with Down syndrome.
Lai F, Mhatre PG, Yang Y, Wang MC, Schupf N, Rosas HD. Alzheimers Dement (Amst). 2020 Sep 13;12(1):e12084. doi: 10.1002/dad2.12084.

White Matter Hyperintensities Predict Response to Language Treatment in Poststroke Aphasia.
Varkanitsa M, Peñaloza C, Charidimou A, Caplan D, Kiran S. Neurorehabil Neural Repair. 2020 Sep 13:1545968320952809. doi: 10.1177/1545968320952809. 


The NEALS primary lateral sclerosis registry.
Paganoni S, De Marchi F, Chan J, Thrower SK, Staff NP, Datta N, Kisanuki YY, Drory V, Fournier C, Pioro EP, Goutman SA, Atassi N; NEALS PLS Registry Study Group. Amyotroph Lateral Scler Frontotemporal Degener. 2020 Sep 11:1-8. doi: 10.1080/21678421.2020.1804591.


Sex and Genetic Background Effects on the Outcome of Experimental Intracranial Aneurysms.
Yanagisawa T, Zhang H, Suzuki T, Kamio Y, Takizawa T, Morais A, Chung DY, Qin T, Murayama Y, Faber JE, Patel AB, Ayata C. Stroke. 2020 Sep 11:STROKEAHA120029651. doi: 10.1161/STROKEAHA.120.029651.


Clinical Reasoning: A 33-year-old with left sided hemiparesis and anarthria.
Schowalter S, Katz DI, Lin DJ. Neurology. 2020 Sep 10:10.1212/WNL.0000000000010809. doi: 10.1212/WNL.0000000000010809.


Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill Patients.
Sheth KN, Mazurek MH, Yuen MM, Cahn BA, Shah JT, Ward A, Kim JA, Gilmore EJ, Falcone GJ, Petersen N, Gobeske KT, Kaddouh F, Hwang DY, Schindler J, Sansing L, Matouk C, Rothberg J, Sze G, Siner J, Rosen MS, Spudich S, Kimberly WT. JAMA Neurol. 2020 Sep 8. doi: 10.1001/jamaneurol.2020.3263.


Huntington's Disease: Les Jeux Sont Faits?
Pfister EL, Aronin N. Trends Mol Med. 2020 Sep 4:S1471-4914(20)30206-9. doi: 10.1016/j.molmed.2020.08.004.


Preoperative Depressive Symptoms Associated with Poor Functional Recovery after Surgery.
Tang VL, Cenzer I, McCulloch CE, Finlayson E, Cooper Z, Silvestrini M, Ngo S, Schmitt EM, Inouye SK. J Am Geriatr Soc. 2020 Sep 8. doi: 10.1111/jgs.16781.


Update on neuromyelitis optica spectrum disorder.
Holroyd KB, Manzano GS, Levy M. Curr Opin Ophthalmol. 2020 Sep 3. doi: 10.1097/ICU.0000000000000703.  


Association of Plasma Neurofilament Light with Postoperative Delirium.
Fong TG, Vasunilashorn SM, Ngo L, Libermann T, Dillon S, Schmitt E, Pascual-Leone A, Arnold SE, Jones R, Marcantonio ER, Inouye SK; SAGES Study Group. Ann Neurol. 2020 Sep 3. doi: 10.1002/ana.25889.


Small but Fierce: Tracking the Role of Extracellular Vesicles in Glioblastoma Progression and Therapeutic Resistance.
Schweiger MW, Tannous BA. Adv Biosyst. 2020 Sep 3:e2000035. doi: 10.1002/adbi.202000035. Online ahead of print. PMID: 32881418


Telemedicine in Behavioral Neurology-Neuropsychiatry: Opportunities and Challenges Catalyzed by COVID-19.
Perez DL, Biffi A, Camprodon JA, Caplan DN, Chemali Z, Kritzer MD, Moo LR, Newhouse AL, Ramirez-Gomez L, Razafsha M, Tanev KS, Schmahmann JD. Cogn Behav Neurol. 2020 Sep;33(3):226-229. doi: 10.1097/WNN.0000000000000239.


"Rocking the boat" with a new drug for neuromyelitis optica spectrum disorder.
Levy M, Lechner-Scott J, Hawkes C, Giovannoni G. Mult Scler Relat Disord. 2020 Sep;44:102458. doi: 10.1016/j.msard.2020.102458.


A Theoretical Paradigm for Evaluating Risk-Benefit of Status Epilepticus Treatment.
Amorim E, McGraw CM, Westover MB. J Clin Neurophysiol. 2020 Sep;37(5):385-392. doi: 10.1097/WNP.0000000000000753.


CLoSES: A platform for closed-loop intracranial stimulation in humans.
Zelmann R, Paulk AC, Basu I, Sarma A, Yousefi A, Crocker B, Eskandar E, Williams Z, Cosgrove GR, Weisholtz DS, Dougherty DD, Truccolo W, Widge AS, Cash SS. Neuroimage. 2020 Aug 31:117314. doi: 10.1016/j.neuroimage.2020.117314.


Neighborhood-Level Social Disadvantage and Risk of Delirium Following Major Surgery.
Arias F, Chen F, Fong TG, Shiff H, Alegria M, Marcantonio ER, Gou Y, Jones RN, Travison TG, Schmitt EM, Kind AJH, Inouye SK. J Am Geriatr Soc. 2020 Aug 31. doi: 10.1111/jgs.16782.


Association of Selective Serotonin Reuptake Inhibitor Use After Intracerebral Hemorrhage With Hemorrhage Recurrence and Depression Severity.
Kubiszewski P, Sugita L, Kourkoulis C, DiPucchio Z, Schwab K, Anderson CD, Gurol ME, Greenberg SM, Viswanathan A, Rosand J, Biffi A. JAMA Neurol. 2020 Aug 31. doi: 10.1001/jamaneurol.2020.3142.


The natural compound obtusaquinone targets pediatric high-grade gliomas through ROS-mediated ER stress.
Teng J, Lashgari G, Tabet EI, Tannous BA. Neurooncol Adv. 2020 Aug 27;2(1):vdaa106. doi: 10.1093/noajnl/vdaa106. eCollection 2020 Jan-Dec.


Anterior Insular Resting-State Functional Connectivity is Related to Cognitive Reserve in Multiple Sclerosis.
Bizzo BC, Arruda-Sanchez T, Tobyne SM, Bireley JD, Lev MH, Gasparetto EL, Klawiter EC. J Neuroimaging. 2020 Aug 28. doi: 10.1111/jon.12779.


Mapping mania symptoms based on focal brain damage.
Cotovio G, Talmasov D, Barahona-Corrêa JB, Hsu J, Senova S, Ribeiro R, Soussand L, Velosa A, Silva VCE, Rost N, Wu O, Cohen AL, Oliveira-Maia AJ, Fox MD. J Clin Invest. 2020 Aug 24:136096. doi: 10.1172/JCI136096.


Engaging ALS patients and caregivers (the ALS research ambassadors) to help design the REFINE-ALS biomarker study.
Berry JD, Bedlack R, Mathews D, Agnese W, Apple S.
Amyotroph Lateral Scler Frontotemporal Degener. 2020 Aug 24:1-4. doi: 10.1080/21678421.2020.1804939.


New gene discoveries highlight functional convergence in autism and related neurodevelopmental disorders.
Moyses-Oliveira M, Yadav R, Erdin S, Talkowski ME. Curr Opin Genet Dev. 2020 Aug 23;65:195-206. doi: 10.1016/j.gde.2020.07.001.


Case 26-2020: A 60-Year-Old Woman with Altered Mental Status and Weakness on the Left Side.
Singhal AB, Gonzalez RG, Chwalisz BK, Mukerji SS. N Engl J Med. 2020 Aug 20;383(8):764-773. doi: 10.1056/NEJMcpc2004976.


Tau reduction in aged mice does not impact Microangiopathy.
Bennett RE, Hu M, Fernandes A, Perez-Rando M, Robbins A, Kamath T, Dujardin S, Hyman BT. Acta Neuropathol Commun. 2020 Aug 18;8(1):137. doi: 10.1186/s40478-020-01014-4.


Discovery of ACE2 receptors for SARS-CoV-2 (COVID-19) on peripheral small-fiber sensory neurons of uncertain clinical significance.
Oaklander AL.
Pain. 2020 Aug 18. doi: 10.1097/j.pain.0000000000002050.


Improved relapse recovery in paediatric compared to adult multiple sclerosis.
Chitnis T, Aaen G, Belman A, Benson L, Gorman M, Goyal MS, Graves JS, Harris Y, Krupp L, Lotze T, Mar S, Ness J, Rensel M, Schreiner T, Tillema JM, Waubant E, Weinstock-Guttman B, Roalstad S, Rose J, Weiner HL, Casper TC, Rodriguez M. Brain. 2020 Aug 18:awaa199. doi: 10.1093/brain/awaa199.


Gene therapy for Alzheimer's Disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation.
Griciuc A, Federico AN, Natasan J, Forte AM, McGinty D, Nguyen H, Volak A, LeRoy S, Gandhi S, Lerner EP, Hudry E, Tanzi RE, Maguire CA. Hum Mol Genet. 2020 Aug 17:ddaa179. doi: 10.1093/hmg/ddaa179.


Sex mediates relationships between regional tau pathology and cognitive decline.
Buckley RF, Scott MR, Jacobs HI, Schultz AP, Properzi MJ, Amarglio RE, Hohman TJ, Mayblyum DV, Rubinstein ZB, Manning L, Hanseeuw BJ, Mormino EC, Rentz DM, Johnson KA, Sperling RA. Ann Neurol. 2020 Aug 16. doi: 10.1002/ana.25878.


An early start to Huntington's disease.
DiFiglia M. Science. 2020 Aug 14;369(6505):771-772. doi: 10.1126/science.abd6215.


Epidermal Neurite Density in Skin Biopsies from Patients with Juvenile Fibromyalgia.
Boneparth A, Chen S, Horton DB, Moorthy LN, Farquhar I, Downs HM, Lee H, Oaklander AL. J Rheumatol. 2020 Aug 15:jrheum.200378. doi: 10.3899/jrheum.200378.


Personalized Connectome Mapping to Guide Targeted Therapy and Promote Recovery of Consciousness in the Intensive Care Unit.
Edlow BL, Barra ME, Zhou DW, Foulkes AS, Snider SB, Threlkeld ZD, Chakravarty S, Kirsch JE, Chan ST, Meisler SL, Bleck TP, Fins JJ, Giacino JT, Hochberg LR, Solt K, Brown EN, Bodien YG. Neurocrit Care. 2020 Aug 13. doi: 10.1007/s12028-020-01062-7.


Purifying Selection against Pathogenic Mitochondrial DNA in Human T Cells.
Walker MA, Lareau CA, Ludwig LS, Karaa A, Sankaran VG, Regev A, Mootha VK. N Engl J Med. 2020 Aug 12. doi: 10.1056/NEJMoa2001265.


Stronger together: Diagnostic testing for ocular myasthenia gravis.
Doughty CT, Guidon AC. Neurology. 2020 Aug 11:10.1212/WNL.0000000000010616. doi: 10.1212/WNL.0000000000010616.


Synergy between amyloid-β and tau in Alzheimer's disease.
Busche MA, Hyman BT. Nat Neurosci. 2020 Aug 10. doi: 10.1038/s41593-020-0687-6.

Rubin DB, Al Jarrah A, Li K, LaRose S, Monk AD, Ali AB, Spendley LN, Nikiforow S, Jacobson C, Vaitkevicius H. JAMA Neurol. 2020 Aug 10. doi: 10.1001/jamaneurol.2020.2703. 

Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints.
Minikel EV, Zhao HT, Le J, O'Moore J, Pitstick R, Graffam S, Carlson GA, Kavanaugh MP, Kriz J, Kim JB, Ma J, Wille H, Aiken J, McKenzie D, Doh-Ura K, Beck M, O'Keefe R, Stathopoulos J, Caron T, Schreiber SL, Carroll JB, Kordasiewicz HB, Cabin DE, Vallabh SM. Nucleic Acids Res. 2020 Aug 10:gkaa616. doi: 10.1093/nar/gkaa616.


Opposing and potentially antagonistic effects of BMP and TGF-β in multiple sclerosis: The "Yin and Yang" of neuro-immune Signaling.
Sotiropoulos MG, Chitnis T. J Neuroimmunol. 2020 Aug 7;347:577358. doi: 10.1016/j.jneuroim.2020.577358.


Accurate detection of spontaneous seizures using a generalized linear model with external validation.
Fumeaux NF, Ebrahim S, Coughlin BF, Kadambi A, Azmi A, Xu JX, Abou Jaoude M, Nagaraj SB, Thomson KE, Newell TG, Metcalf CS, Wilcox KS, Kimchi EY, Moraes MFD, Cash SS. Epilepsia. 2020 Aug 6. doi: 10.1111/epi.16628.


Association of epileptiform abnormalities and seizures in Alzheimer disease.
Lam AD, Sarkis RA, Pellerin KR, Jing J, Dworetzky BA, Hoch DB, Jacobs CS, Lee JW, Weisholtz DS, Zepeda R, Westover MB, Cole AJ, Cash SS. Neurology. 2020 Aug 6:10.1212/WNL.0000000000010612. doi: 10.1212/WNL.0000000000010612. 


Mobility Action Group: Using Quality Improvement Methods to Create a Culture of Hospital Mobility.
Lorgunpai SJ, Finke B, Burrows I, Brown CJ, Rubin FH, Wierman HR, Heisey SJ, Gartaganis S, Ling SM, Press M, Inouye SK. J Am Geriatr Soc. 2020 Aug 5. doi: 10.1111/jgs.16699.


Author response: Disruption of the ascending arousal network in acute traumatic disorders of consciousness.
Edlow BL, Snider SB. Neurology. 2020 Aug 4;95(5):234. doi: 10.1212/WNL.0000000000010099.


Periodic Oscillations in Daily Reported Infections and Deaths for Coronavirus Disease 2019.
Bukhari Q, Jameel Y, Massaro JM, D'Agostino RB Sr, Khan S. JAMA Netw Open. 2020 Aug 3;3(8):e2017521. doi: 10.1001/jamanetworkopen.2020.17521.


Short-term Palliative Care for Advanced Neurologic Disease.
Brizzi KT. JAMA Netw Open. 2020 Aug 3;3(8):e2015247. doi: 10.1001/jamanetworkopen.2020.15247. PMID: 32857143


CRMP-5-IgG Associated Paraneoplastic Chorea.
Vaswani PA, Kimchi EY, Hung AY. Mov Disord Clin Pract. 2020 Aug 3;7(6):713-715. doi: 10.1002/mdc3.13019.


Exploring the use of educational materials for increasing participation in a stretching program: a quality improvement project in people with motor neuron disease.
Burke K, De Marchi F, Ellrodt AS, Doyle M, Koul M, Comeau O, Adelson E, Walter R, Kusy M, Amaya F, Anderson C, Honda J, Chan J, Berry J, Paganoni S. Eur J Phys Rehabil Med. 2020 Aug 3. doi: 10.23736/S1973-9087.20.06245-0. Online ahead of print.


Amyotrophic Lateral Sclerosis: Fuel for the Corticofugal Feud.
Wainger BJ, Brown RH Jr. Ann Neurol. 2020 Aug 2. doi: 10.1002/ana.25861. Online ahead of print.


Clinical Trial Readiness Study of Distal Myopathy and Dysphagia in Nephropathic Cystinosis.
Sadjadi R, Sullivan S, Grant N, Thomas SE, Doyle M, Hammond C, Corre C, Mello N, David WS, Eichler F. Muscle Nerve. 2020 Aug 1. doi: 10.1002/mus.27039. Online ahead of print.


Editorial: Advances in rare movement disorders.
Sharma N. Curr Opin Neurol. 2020 Aug;33(4):498-499. doi: 10.1097/WCO.0000000000000830.


Meta-analysis of mouse transcriptomic studies supports a context-dependent astrocyte reaction in acute CNS injury versus neurodegeneration.
Das S, Li Z, Noori A, Hyman BT, Serrano-Pozo A. J Neuroinflammation. 2020 Jul 31;17(1):227. doi: 10.1186/s12974-020-01898-y.
PMID: 32736565


Lower extremity entrapment neuropathies.
Madani S, Doughty C. Best Pract Res Clin Rheumatol. 2020 Jul 31:101565. doi: 10.1016/j.berh.2020.101565. Online ahead of print. PMID: 32747188


Neuroinflammation and histone H3 citrullination are increased in X-linked Dystonia Parkinsonism post-mortem prefrontal cortex.
Petrozziello T, Mills AN, Vaine CA, Penney EB, Fernandez-Cerado C, Legarda GPA, Velasco-Andrada MS, Acuña PJ, Ang MA, Muñoz EL, Diesta CCE, Macalintal-Canlas R, Acuña-Sunshine G, Ozelius LJ, Sharma N, Bragg DC, Sadri-Vakili G. Neurobiol Dis. 2020 Jul 30:105032. doi: 10.1016/j.nbd.2020.105032. Online ahead of print.
PMID: 32739252


Detecting Seizures and Epileptiform Abnormalities in Acute Brain Injury.
Singla S, Garcia GE, Rovenolt GE, Soto AL, Gilmore EJ, Hirsch LJ, Blumenfeld H, Sheth KN, Omay SB, Struck AF, Westover MB, Kim JA. Curr Neurol Neurosci Rep. 2020 Jul 27;20(9):42. doi: 10.1007/s11910-020-01060-4.
PMID: 32715371


Sirtuin activation targets IDH-mutant tumors.
Miller JJ, Fink A, Banagis JA, Nagashima H, Subramanian M, Lee CK, Melamed L, Tummala SS, Tateishi K, Wakimoto H, Cahill DP. Neuro Oncol. 2020 Jul 26:noaa180. doi: 10.1093/neuonc/noaa180. Online ahead of print.
PMID: 32710757


Hospital Elder Life Program in Long-Term Care (HELP-LTC): A Cluster Randomized Controlled Trial.
Boockvar KS, Judon KM, Eimicke JP, Teresi JA, Inouye SK. J Am Geriatr Soc. 2020 Jul 25. doi: 10.1111/jgs.16695.


The Consequences of Coronavirus-Induced Cytokine Storm Are Associated With Neurological Diseases, Which May Be Preventable.
Isacson O.
Front Neurol. 2020 Jul 24;11:745. doi: 10.3389/fneur.2020.00745. eCollection 2020.


Cerebral Microvascular Injury in Severe COVID-19.
Conklin J, Frosch MP, Mukerji S, Rapalino O, Maher M, Schaefer PW, Lev MH, Gonzalez RG, Das S, Champion SN, Magdamo C, Sen P, Harrold GK, Alabsi H, Normandin E, Shaw B, Lemieux J, Sabeti P, Branda JA, Brown EN, Westover MB, Huang SY, Edlow BL. medRxiv. 2020 Jul 24:2020.07.21.20159376. doi: 10.1101/2020.07.21.20159376. Preprint.


Identification of TNFAIP3 as relapse biomarker and potential therapeutic target for MOG antibody associated diseases.
Saxena S, Lokhande H, Gombolay G, Raheja R, Rooney T, Chitnis T. Sci Rep. 2020 Jul 24;10(1):12405. doi: 10.1038/s41598-020-69182-w.


Dementia Unspecified: A Multidisciplinary Approach.
Newhouse A, Buch K, Chemali Z. Prim Care Companion CNS Disord. 2020 Jul 23;22(4):19nr02570. doi: 10.4088/PCC.19nr02570.


Clinical Outcomes and Selection Criteria for Prodromal Huntington's Disease Trials.
Langbehn DR, Hersch S. Mov Disord. 2020 Jul 20. doi: 10.1002/mds.28222.


Opportunities of Connectomic Neuromodulation.
Horn A, Fox MD. Neuroimage. 2020 Jul 20:117180. doi: 10.1016/j.neuroimage.2020.117180.


Brain edema takes center stage.
Sheth KN, Kimberly WT. Neurosci Lett. 2020 Jul 20;736:135266. doi: 10.1016/j.neulet.2020.135266.


Pediatric Multiple Sclerosis Severity Score in a Large U.S. Cohort.
Santoro JD, Waltz M, Aaen G, Belman A, Benson L, Gorman M, Goyal MS, Graves JS, Harris Y, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Rensel M, Rodriguez M, Schreiner T, Tillema JM, Waubant E, Weinstock-Guttman B, Hurtubise BF, Roalstad S, Rose J, Casper TC, Chitnis T; U.S. Network of Pediatric MS Centers. Neurology. 2020 Jul 20:10.1212/WNL.0000000000010414. doi: 10.1212/WNL.0000000000010414.


Clinical Electroencephalography Findings and Considerations in Hospitalized Patients with Coronavirus SARS-CoV-2.
Ayub N, Cohen J, Jing J, Jain A, Tesh R, Mukerji SS, Zafar SF, Westover MB, Kimchi EY. medRxiv. 2020 Jul 15:2020.07.13.20152207. doi: 10.1101/2020.07.13.20152207. Preprint.


Creutzfeldt-Jakob disease in a man with COVID-19: SARS-CoV-2-accelerated neurodegeneration?
Young MJ, O'Hare M, Matiello M, Schmahmann JD. Brain Behav Immun. 2020 Jul 15:S0889-1591(20)31522-1. doi: 10.1016/j.bbi.2020.07.007.


Safety Considerations for Cerebellar Theta Burst Stimulation.
Hurtado-Puerto AM, Nestor K, Eldaief M, Camprodon JA. Clin Ther. 2020 Jul 14:S0149-2918(20)30279-4. doi: 10.1016/j.clinthera.2020.06.001.


Corrigendum: Interhemispheric and Intrahemispheric Connectivity From the Left Pars Opercularis Within the Language Network Is Modulated by Transcranial Stimulation in Healthy Subjects.
Yoo WK, Vernet M, Kim JH, Brem AK, Bashir S, Ifert-Miller F, Im CH, Eldaief M, Pascual-Leone A. Front Hum Neurosci. 2020 Jul 14;14:249. doi: 10.3389/fnhum.2020.00249.

The Role of Inflammation after Surgery for Elders (RISE) study: Examination of [11C]PBR28 binding and exploration of its link to post-operative delirium.
Katsumi Y, Racine AM, Torrado-Carvajal A, Loggia ML, Hooker JM, Greve DN, Hightower BG, Catana C, Cavallari M, Arnold SE, Fong TG, Vasunilashorn SM, Marcantonio ER, Schmitt EM, Xu G, Libermann TA, Barrett LF, Inouye SK, Dickerson BC, Touroutoglou A, Collins JA; RISE Study Group. Neuroimage Clin. 2020 Jul 14;27:102346. doi: 10.1016/j.nicl.2020.102346. 


Delineating the phenotypic spectrum of sulfite oxidase and molybdenum cofactor deficiency.
Misko AL, Liang Y, Kohl JB, Eichler F. Neurol Genet. 2020 Jul 14;6(4):e486. doi: 10.1212/NXG.0000000000000486. eCollection 2020 Aug.


Cost-effectiveness analysis of multimodal prognostication in cardiac arrest with EEG monitoring.
Amorim E, Mo SS, Palacios S, Ghassemi MM, Weng WH, Cash SS, Bianchi MT, Westover MB. Neurology. 2020 Jul 13:10.1212/WNL.0000000000009916. doi: 10.1212/WNL.0000000000009916.

Genomic Mechanisms in Alzheimer's Disease.
Bertram L, Tanzi RE. Brain Pathol. 2020 Jul 13. doi: 10.1111/bpa.12882.


Accuracy of ICD-10-CM claims-based definitions for epilepsy and seizure type.
Smith JR, Jones FJS, Fureman BE, Buchhalter JR, Herman ST, Ayub N, McGraw C, Cash SS, Hoch DB, Moura LMVR. Epilepsy Res. 2020 Jul 11;166:106414. doi: 10.1016/j.eplepsyres.2020.106414.


Neuromyelitis optica practice and prescribing changes in the setting of Covid19: A survey of neurologists.
Rezaei SJ, Vogel AC, Gazdag B, Alakel N, Kumar AR, Mateen FJ. J Neuroimmunol. 2020 Jul 11;346:577320. doi: 10.1016/j.jneuroim.2020.577320


Optimizing the accuracy of cortical volumetric analysis in traumatic brain injury.
Diamond BR, Donald CLM, Frau-Pascual A, Snider SB, Fischl B, Dams-O'Connor K, Edlow BL. MethodsX. 2020 Jul 11;7:100994. doi: 10.1016/j.mex.2020.100994. eCollection 2020.


Transitive Sequencing Medical Records for Mining Predictive and Interpretable Temporal Representations.
Estiri H, Strasser ZH, Klann JG, McCoy TH Jr, Wagholikar KB, Vasey S, Castro VM, Murphy ME, Murphy SN. Patterns (N Y). 2020 Jul 10;1(4):100051. doi: 10.1016/j.patter.2020.100051. Epub 2020 Jun 18.


Experimental studies of mitochondrial and lysosomal function in in vitro and in vivo models relevant to Parkinson's disease genetic risk.
Thomas R, Hallett PJ, Isacson O. Int Rev Neurobiol. 2020;154:279-302. doi: 10.1016/bs.irn.2020.02.004. Epub 2020 Jul 10.
PMID: 32739007


Peri-Infarct Hot-Zones Have Higher Susceptibility to Optogenetic Functional Activation-Induced Spreading Depolarizations.
Sugimoto K, Chung DY, Böhm M, Fischer P, Takizawa T, Aslihan Aykan S, Qin T, Yanagisawa T, Harriott A, Oka F, Yaseen MA, Sakadžić S, Ayata C. Stroke. 2020 Jul 9:STROKEAHA120029618. doi: 10.1161/STROKEAHA.120.029618. Online ahead of print.
PMID: 32640946


National Geriatric Network Rapidly Addresses Trainee Telehealth Needs in Response to COVID-19.
Nearing KA, Lum HD, Dang S, Powers B, McLaren J, Gately M, Hung W, Moo L. J Am Geriatr Soc. 2020 Jul 8. doi: 10.1111/jgs.16704. [Epub ahead of print] PMID: 32639578


Impact of COVID-19 on U.S. and Canadian neurologists' therapeutic approach to multiple sclerosis: a survey of knowledge, attitudes, and practices.
Mateen FJ, Rezaei S, Alakel N, Gazdag B, Kumar AR, Vogel A. J Neurol. 2020 Jul 7. doi: 10.1007/s00415-020-10045-9. [Epub ahead of print]
PMID: 32638107


Advances toward precision medicine for bipolar disorder: mechanisms & molecules.
Haggarty SJ, Karmacharya R, Perlis RH. Mol Psychiatry. 2020 Jul 7. doi: 10.1038/s41380-020-0831-4. [Epub ahead of print] Review.
PMID: 32636474


Patterns of CAG repeat instability in the central nervous system and periphery in Huntington's disease and in spinocerebellar ataxia type 1.
Mouro Pinto R, Arning L, Giordano JV, Razghandi P, Andrew MA, Gillis T, Correia K, Mysore JS, Grote Urtubey DM, Parwez CR, Hein von SM, Clark HB, Nguyen HP, Förster E, Beller A, Jayadaev S, Keene CD, Bird TD, Lucente D, Vonsattel JP, Orr H, Saft C, Petrasch-Parwez E, Wheeler VC. Hum Mol Genet. 2020 Jul 7:ddaa139. doi: 10.1093/hmg/ddaa139.


Temporal profile of lymphocyte counts and relationship with infections with fingolimod therapy in paediatric patients with multiple sclerosis: Results from the PARADIGMS study.
Chitnis T, Banwell B, Krupp L, Arnold DL, Bar-Or A, Brück W, Giovannoni G, Greenberg B, Ghezzi A, Waubant E, Rostasy K, Deiva K, Huppke P, Wolinsky JS, Zhang Y, Azmon A, K-Laflamme A, Karan R, Gärtner J. Mult Scler. 2020 Jul 7:1352458520936934. doi: 10.1177/1352458520936934. [Epub ahead of print]
PMID: 32633694


Intact Brain Network Function in an Unresponsive Patient with COVID-19.
Fischer D, Threlkeld ZD, Bodien YG, Kirsch JE, Huang SY, Schaefer PW, Rapalino O, Hochberg LR, Rosen BR, Edlow BL. Ann Neurol. 2020 Jul 1. doi: 10.1002/ana.25838. [Epub ahead of print]
PMID: 32613682


White Matter Atrophy in Cerebral Amyloid Angiopathy.
Fotiadis P, Reijmer YD, Van Veluw SJ, Martinez-Ramirez S, Karahanoglu FI, Gokcal E, Schwab KM; Alzheimer’s Disease Neuroimaging Initiative study group, Goldstein JN, Rosand J, Viswanathan A, Greenberg SM, Gurol ME. Neurology. 2020 Jul 1. pii: 10.1212/WNL.0000000000010017. doi: 10.1212/WNL.0000000000010017. [Epub ahead of print]
PMID: 32611644


Zika Virus: Learning from the Past as We Prepare for the Future.
Mochida GH. J Pediatr. 2020 Jul;222:15-16. doi: 10.1016/j.jpeds.2020.04.006.
PMID: 32586516


Slow Wave Sleep Is a Promising Intervention Target for Alzheimer's Disease.
Lee YF, Gerashchenko D, Timofeev I, Bacskai BJ, Kastanenka KV. Front Neurosci. 2020 Jun 30;14:705. doi: 10.3389/fnins.2020.00705. eCollection 2020.
PMID: 32714142


Thrombolysis beyond 4.5 h in Acute Ischemic Stroke.
Etherton MR, Gadhia RR, Schwamm LH. Curr Neurol Neurosci Rep. 2020 Jun 30;20(8):35. doi: 10.1007/s11910-020-01055-1. Review.
PMID: 32607627


Evaluating the Clinical Impact of Rapid Response Electroencephalography: The DECIDE Multicenter Prospective Observational Clinical Study.
Vespa PM, Olson DM, John S, Hobbs KS, Gururangan K, Nie K, Desai MJ, Markert M, Parvizi J, Bleck TP, Hirsch LJ, Westover MB. Crit Care Med. 2020 Jun 29. doi: 10.1097/CCM.0000000000004428. [Epub ahead of print]
PMID: 32618687


Leaky memories: Impact of APOE4 on blood-brain barrier and dementia.
Li W, Lo EH. J Cereb Blood Flow Metab. 2020 Jun 29:271678X20938146. doi: 10.1177/0271678X20938146. [Epub ahead of print]
PMID: 32600092


Disease of the Year: COVID-19 and Its Neuro-ophthalmic Complications.
Chwalisz BK, Dinkin MJ. J Neuroophthalmol. 2020 Jun 26. doi: 10.1097/WNO.0000000000001046. [Epub ahead of print] PMID: 32604246 


Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons.
Silva MC, Nandi GA, Tentarelli S, Gurrell IK, Jamier T, Lucente D, Dickerson BC, Brown DG, Brandon NJ, Haggarty SJ. Nat Commun. 2020 Jun 26;11(1):3258. doi: 10.1038/s41467-020-16984-1.
PMID: 32591533


A standardized nomenclature for spectrogram EEG patterns: Inter-rater agreement and correspondence with common intensive care unit EEG patterns.
Zafar SF, Amorim E, Williamsom CA, Jing J, Gilmore EJ, Haider HA, Swisher C, Struck A, Rosenthal ES, Ng M, Schmitt S, Lee JW, Brandon Westover M. Clin Neurophysiol. 2020 Jun 24:S1388-2457(20)30369-2. doi: 10.1016/j.clinph.2020.05.032. Online ahead of print.
PMID: 32660817


Upregulation of Alzheimer's Disease Amyloid-β Protein Precursor in Astrocytes Both in vitro and in vivo.
Liang Y, Raven F, Ward JF, Zhen S, Zhang S, Sun H, Miller SJ, Choi SH, Tanzi RE, Zhang C. J Alzheimers Dis. 2020 Jun 24. doi: 10.3233/JAD-200128. [Epub ahead of print]
PMID: 32597805


Tau PET imaging with 18F-PI-2620 in aging and neurodegenerative diseases.
Mormino EC, Toueg TN, Azevedo C, Castillo JB, Guo W, Nadiadwala A, Corso NK, Hall JN, Fan A, Trelle AN, Harrison MB, Hunt MP, Sha SJ, Deutsch G, James M, Fredericks CA, Koran ME, Zeineh M, Poston K, Greicius MD, Khalighi M, Davidzon GA, Shen B, Zaharchuk G, Wagner AD, Chin FT. Eur J Nucl Med Mol Imaging. 2020 Jun 23. doi: 10.1007/s00259-020-04923-7. [Epub ahead of print]
PMID: 32572562


COVID-19 Outpatient Screening: a Prediction Score for Adverse Events.
Sun H, Jain A, Leone MJ, Alabsi HS, Brenner LN, Ye E, Ge W, Shao YP, Boutros CL, Wang R, Tesh RA, Magdamo C, Collens SI, Ganglberger W, Bassett IV, Meigs JB, Kalpathy-Cramer J, Li MD, Chu JT, Dougan M, Stratton L, Rosand J, Fischl B, Das S, Mukerji SS, Robbins GK, Westover MB. medRxiv. 2020 Jun 22. pii: 2020.06.17.20134262. doi: 10.1101/2020.06.17.20134262.
PMID: 32607523


Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease.
Dujardin S, Commins C, Lathuiliere A, Beerepoot P, Fernandes AR, Kamath TV, De Los Santos MB, Klickstein N, Corjuc DL, Corjuc BT, Dooley PM, Viode A, Oakley DH, Moore BD, Mullin K, Jean-Gilles D, Clark R, Atchison K, Moore R, Chibnik LB, Tanzi RE, Frosch MP, Serrano-Pozo A, Elwood F, Steen JA, Kennedy ME, Hyman BT.
Nat Med. 2020 Jun 22. doi: 10.1038/s41591-020-0938-9. [Epub ahead of print]
PMID: 32572268


Association Between Immunosuppressive Treatment and Outcomes of Cerebral Amyloid Angiopathy-Related Inflammation.
Regenhardt RW, Thon JM, Das AS, Thon OR, Charidimou A, Viswanathan A, Gurol ME, Chwalisz BK, Frosch MP, Cho TA, Greenberg SM. JAMA Neurol. 2020 Jun 22. doi: 10.1001/jamaneurol.2020.1782. [Epub ahead of print]
PMID: 32568365


Chasing Protection in Parkinson's Disease: Does Exercise Reduce Risk and Progression?
Crotty GF, Schwarzschild MA. Front Aging Neurosci. 2020 Jun 19;12:186. doi: 10.3389/fnagi.2020.00186. eCollection 2020. Review.
PMID: 32636740


Commentary in response to 'Impact of the COVID-19 pandemic on the process and outcome of thrombectomy for acute ischemic stroke'.
Leslie-Mazwi TM, Chandra RV, Hirsch JA. J Neurointerv Surg. 2020 Jun 19. pii: neurintsurg-2020-016426. doi: 10.1136/neurintsurg-2020-016426. [Epub ahead of print]
PMID: 32561659 


Determining the Need for Thrombectomy-Capable Stroke Centers Based on Travel Time to the Nearest Comprehensive Stroke Center.
Baker DW, Tschurtz BA, Aliaga AE, Williams SC, Jauch EC, Schwamm LH. Jt Comm J Qual Patient Saf. 2020 Jun 18:S1553-7250(20)30157-4. doi: 10.1016/j.jcjq.2020.06.005. Online ahead of print.
PMID: 32736996


Brain insulin signaling, Alzheimer's disease pathology, and cognitive function.
Arvanitakis Z, Wang HY, Capuano AW, Khan A, Taïb B, Anokye-Danso F, Schneider JA, Bennett DA, Ahima RS, Arnold SE. Ann Neurol. 2020 Jun 18. doi: 10.1002/ana.25826. [Epub ahead of print]
PMID: 32557841


Cerebrospinal fluid and plasma biomarkers in individuals at risk for genetic prion disease.
Vallabh SM, Minikel EV, Williams VJ, Carlyle BC, McManus AJ, Wennick CD, Bolling A, Trombetta BA, Urick D, Nobuhara CK, Gerber J, Duddy H, Lachmann I, Stehmann C, Collins SJ, Blennow K, Zetterberg H, Arnold SE. BMC Med. 2020 Jun 18;18(1):140. doi: 10.1186/s12916-020-01608-8.
PMID: 32552681


High mitochondrial calcium levels precede neuronal death in vivo in Alzheimer's disease.
Calvo-Rodriguez M, Bacskai BJ. Cell Stress. 2020 Jun 18;4(7):187-190. doi: 10.15698/cst2020.07.226.
PMID: 32656500


Whole-blood dysregulation of actin-cytoskeleton pathway in adult spinal muscular atrophy patients.
Siranosian JJ, Nery FC, Alves CRR, Siranosian BA, Lyons NJ, Eichelberger EJ, Garner R, Da Silva Duarte Lepez S, Johnstone AJ, Subramanian A, Swoboda KJ. Ann Clin Transl Neurol. 2020 Jun 17. doi: 10.1002/acn3.51092. [Epub ahead of print]
PMID: 32558393


Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects.
Kim KH, Hong EP, Shin JW, Chao MJ, Loupe J, Gillis T, Mysore JS, Holmans P, Jones L, Orth M, Monckton DG, Long JD, Kwak S, Lee R, Gusella JF, MacDonald ME, Lee JM. Am J Hum Genet. 2020 Jun 16. pii: S0002-9297(20)30159-2. doi: 10.1016/j.ajhg.2020.05.012. [Epub ahead of print]
PMID: 32589923


Innate immune signaling in the olfactory epithelium reduces odorant receptor levels: modeling transient smell loss in COVID-19 patients.
Rodriguez S, Cao L, Rickenbacher GT, Benz EG, Magdamo C, Ramirez Gomez LA, Holbrook E, Dhilla Albers A, Gallagher R, Westover MB, Evans KE, Tatar D, Mukerji S, Zafonte R, Boyer EW, Yu CR, Albers MW. medRxiv. 2020 Jun 16. pii: 2020.06.14.20131128. doi: 10.1101/2020.06.14.20131128.
PMID: 32587994


Implementing standardized provider documentation in a tertiary epilepsy clinic.
Jones FJS, Smith JR, Ayub N, Herman ST, Buchhalter JR, Fureman BE, Cash SS, Hoch DB, Moura LMVR. Neurology. 2020 Jun 16. pii: 10.1212/WNL.0000000000009778. doi: 10.1212/WNL.0000000000009778. [Epub ahead of print]
PMID: 32546650


Stander Use in Spinal Muscular Atrophy: Results From a Large Natural History Database.
Townsend EL, Simeone SD, Krosschell KJ, Zhang RZ, Swoboda KJ; Project Cure SMA Investigatorʼs Network. Pediatr Phys Ther. 2020 Jun 16. doi: 10.1097/PEP.0000000000000713. [Epub ahead of print]
PMID: 32569095


Characterizing Sunflower syndrome: a clinical series.
Barnett JR, Fleming BM, Geenen KR, Sourbron J, Freedman JH, Bruno PL, Thiele EA. Epileptic Disord. 2020 Jun 15. doi: 10.1684/epd.2020.1161. [Epub ahead of print]
PMID: 32554362


β-Glucocerebrosidase Activity in GBA-linked Parkinson's Disease: The Type of Mutation Matters.
Huh YE, Ruby Chiang MS, Locascio JJ, Liao Z, Liu G, Choudhury K, Kuras YI, Tuncali I, Videnovic A, Hunt AL, Schwarzschild MA, Hung AY, Herrington TM, Hayes MT, Hyman BT, Wills AM, Gomperts SN, Growdon JH, Sardi SP, Scherzer CR. Neurology. 2020 Jun 15. pii: 10.1212/WNL.0000000000009989. doi: 10.1212/WNL.0000000000009989. [Epub ahead of print]
PMID: 32540937


Author Correction: Potential circadian effects on translational failure for neuroprotection.
Esposito E, Li W, Mandeville ET, Park JH, Şencan I, Guo S, Shi J, Lan J, Lee J, Hayakawa K, Sakadžić S, Ji X, Lo EH. Nature. 2020 Jun 13. doi: 10.1038/s41586-020-2427-1. [Epub ahead of print]
PMID: 32533095


A computational paradigm for real-time MEG neurofeedback for dynamic allocation of spatial attention.
Rana KD, Khan S, Hämäläinen MS, Vaina LM. Biomed Eng Online. 2020 Jun 12;19(1):45. doi: 10.1186/s12938-020-00787-y.
PMID: 32532277


Neurological Manifestation of COVID-19 and the Enhanced Role of Physiatrists.
Iaccarino MA, Tenforde AS, Zafonte RD, Silver JK, Hefner J, Paganoni S. Am J Phys Med Rehabil. 2020 Jun 10. doi: 10.1097/PHM.0000000000001502. [Epub ahead of print]
PMID: 32541351


Combining Imaging and Genetics to Predict Recurrence of Anticoagulation-Associated Intracerebral Hemorrhage.
Biffi A, Urday S, Kubiszewski P, Gilkerson L, Sekar P, Rodriguez-Torres A, Bettin M, Charidimou A, Pasi M, Kourkoulis C, Schwab K, DiPucchio Z, Behymer T, Osborne J, Morgan M, Moomaw CJ, James ML, Greenberg SM, Viswanathan A, Gurol ME, Worrall BB, Testai FD, McCauley JL, Falcone GJ, Langefeld CD, Anderson CD, Kamel H, Woo D, Sheth KN, Rosand J. Stroke. 2020 Jun 10:STROKEAHA120028310. doi: 10.1161/STROKEAHA.120.028310. [Epub ahead of print]
PMID: 32517581


Pemetrexed in Recurrent or Progressive Central Nervous System Lymphoma: A Phase I Multicenter Clinical Trial.
Dietrich J, Versmee L, Drappatz J, Eichler AF, Nayak L, Norden A, Wong E, Pisapia MR, Jones SS, Gordon AB, Chabner BA, Hochberg F, Batchelor TT. Oncologist. 2020 Jun 10. doi: 10.1634/theoncologist.2020-0489. [Epub ahead of print]
PMID: 32520407 


Longitudinal biomarkers in amyotrophic lateral sclerosis.
Huang F, Zhu Y, Hsiao-Nakamoto J, Tang X, Dugas JC, Moscovitch-Lopatin M, Glass JD, Brown RH Jr, Ladha SS, Lacomis D, Harris JM, Scearce-Levie K, Ho C, Bowser R, Berry JD. Ann Clin Transl Neurol. 2020 Jun 9. doi: 10.1002/acn3.51078. [Epub ahead of print]
PMID: 32515902


Extracellular Vesicles Induce Mesenchymal Transition and Therapeutic Resistance in Glioblastomas through NF-κB/STAT3 Signaling.
Schweiger MW, Li M, Giovanazzi A, Fleming RL, Tabet EI, Nakano I, Würdinger T, Chiocca EA, Tian T, Tannous BA.
Adv Biosyst. 2020 Jun 9:e1900312. doi: 10.1002/adbi.201900312. [Epub ahead of print]
PMID: 32519463 


Genetics of Gene Expression in the Aging Human Brain Reveal TDP-43 Proteinopathy Pathophysiology.
Yang HS, White CC, Klein HU, Yu L, Gaiteri C, Ma Y, Felsky D, Mostafavi S, Petyuk VA, Sperling RA, Ertekin-Taner N, Schneider JA, Bennett DA, De Jager PL. Neuron. 2020 Jun 8. pii: S0896-6273(20)30356-1. doi: 10.1016/j.neuron.2020.05.010. [Epub ahead of print]
PMID: 32526197


FastSurfer - A fast and accurate deep learning based neuroimaging pipeline.
Henschel L, Conjeti S, Estrada S, Diers K, Fischl B, Reuter M. Neuroimage. 2020 Jun 8:117012. doi: 10.1016/j.neuroimage.2020.117012. [Epub ahead of print]
PMID: 32526386


Advances in rare movement disorders.
Sharma N. Curr Opin Neurol. 2020 Jun 8. doi: 10.1097/WCO.0000000000000830. [Epub ahead of print]
PMID: 32520806


Whole Blood SMN Protein Levels Correlate with Severity of Denervation in Spinal Muscular Atrophy.
Alves CRR, Zhang R, Johnstone AJ, Garner R, Eichelberger EJ, Da Silva Duarte Lepez S, Yi V, Stevens V, Poxson R, Schwartz R, Zaworski P, Swoboda KJ. Muscle Nerve. 2020 Jun 8. doi: 10.1002/mus.26995. [Epub ahead of print]
PMID: 32511765


Exploring Predictors of Response to Dacomitinib in EGFR-Amplified Recurrent Glioblastoma.
Chi AS, Cahill DP, Reardon DA, Wen PY, Mikkelsen T, Peereboom DM, Wong ET, Gerstner ER, Dietrich J, Plotkin SR, Norden AD, Lee EQ, Nayak L, Tanaka S, Wakimoto H, Lelic N, Koerner MV, Klofas LK, Bertalan MS, Arrillaga-Romany IC, Betensky RA, Curry WT, Borger DR, Balaj L, Kitchen RR, Chakrabortty SK, Valentino MD, Skog J, Breakefield XO, Iafrate AJ, Batchelor TT. JCO Precis Oncol. 2020 Jun 8;4:PO.19.00295. doi: 10.1200/PO.19.00295.


Using Brain Imaging to Improve Spatial Targeting of Transcranial Magnetic Stimulation for Depression.
Cash RFH, Weigand A, Zalesky A, Siddiqi SH, Downar J, Fitzgerald PB, Fox MD. Biol Psychiatry. 2020 Jun 7:S0006-3223(20)31668-1. doi: 10.1016/j.biopsych.2020.05.033.


Metabolic heterogeneity and adaptability in brain tumors.
Badr CE, Silver DJ, Siebzehnrubl FA, Deleyrolle LP. Cell Mol Life Sci. 2020 Jun 6. doi: 10.1007/s00018-020-03569-w. [Epub ahead of print] Review.
PMID: 32506168


Inferior temporal tau is associated with accelerated prospective cortical thinning in clinically normal older adults.
Scott MR, Hampton OL, Buckley RF, Chhatwal JP, Hanseeuw BJ, Jacobs HIL, Properzi MJ, Sanchez JS, Johnson KA, Sperling RA, Schultz AP.Neuroimage. 2020 Jun 5:116991. doi: 10.1016/j.neuroimage.2020.116991. [Epub ahead of print]
PMID: 32512123


Transcriptional consequences of MBD5 disruption in mouse brain and CRISPR-derived neurons.
Seabra CM, Aneichyk T, Erdin S, Tai DJC, De Esch CEF, Razaz P, An Y, Manavalan P, Ragavendran A, Stortchevoi A, Abad C, Young JI, Maciel P, Talkowski ME, Gusella JF. Mol Autism. 2020 Jun 5;11(1):45. doi: 10.1186/s13229-020-00354-1.
PMID: 32503625


Effect of Mandarin Verb Network Strengthening Treatment (VNeST) in Mandarin-English bilinguals with aphasia: A single-case experimental design.
Li R, Li W, Kiran S. Neuropsychol Rehabil. 2020 Jun 5:1-30. doi: 10.1080/09602011.2020.1773278. [Epub ahead of print]
PMID: 32498670


Pre-treatment graph measures of a functional semantic network are associated with naming therapy outcomes in chronic aphasia.
Johnson JP, Meier EL, Pan Y, Kiran S. Brain Lang. 2020 Jun 4;207:104809. doi: 10.1016/j.bandl.2020.104809. [Epub ahead of print]
PMID: 32505940


White matter hyperintensity burden in acute stroke patients differs by ischemic stroke subtype.
Giese AK, Schirmer MD, Dalca AV, Sridharan R, Donahue KL, Nardin M, Irie R, McIntosh EC, Mocking SJT, Xu H, Cole JW, Giralt-Steinhauer E, Jimenez-Conde J, Jern C, Kleindorfer DO, Lemmens R, Wasselius J, Lindgren A, Rundek T, Sacco RL, Schmidt R, Sharma P, Slowik A, Thijs V, Worrall BB, Woo D, Kittner SJ, McArdle PF, Mitchell BD, Rosand J, Meschia JF, Wu O, Golland P, Rost NS; International Stroke Genetics Consortium and the MRI-GENIE Investigators. Neurology. 2020 Jun 3. pii: 10.1212/WNL.0000000000009728. doi: 10.1212/WNL.0000000000009728. [Epub ahead of print]
PMID: 32493718


Changes in patient and physician attitudes resulting from COVID-19 in neuromyelitis optica spectrum disorder and multiple sclerosis.
Salama S, Giovannoni G, Hawkes CH, Lechner-Scott J, Waubant E, Levy M. Mult Scler Relat Disord. 2020 Jul;42:102259. doi: 10.1016/j.msard.2020.102259. Epub 2020 Jun 3.
PMID: 32571580


Potential circadian effects on translational failure for neuroprotection.
Esposito E, Li W, T Mandeville E, Park JH, Şencan I, Guo S, Shi J, Lan J, Lee J, Hayakawa K, Sakadžić S, Ji X, Lo EH. Nature. 2020 Jun 3. doi: 10.1038/s41586-020-2348-z. [Epub ahead of print]
PMID: 32494010


COVID-19 and neuromuscular disorders.
Guidon AC, Amato AA. Neurology. 2020 Jun 2;94(22):959-969. doi: 10.1212/WNL.0000000000009566. Epub 2020 Apr 13. Review.
PMID: 32284362


Defining Treatment-Related Adverse Effects in Patients with Glioma: Distinctive Features of Pseudoprogression and Treatment-Induced Necrosis.
Winter SF, Vaios EJ, Muzikansky A, Martinez-Lage M, Bussière MR, Shih HA, Loeffler J, Karschnia P, Loebel F, Vajkoczy P, Dietrich J. Oncologist. 2020 Jun 2. doi: 10.1634/theoncologist.2020-0085. [Epub ahead of print]
PMID: 32488924


Vagus Nerve Stimulation Paired With Upper-Limb Rehabilitation After Stroke: One-Year Follow-up.
Dawson J, Engineer ND, Prudente CN, Pierce D, Francisco G, Yozbatiran N, Tarver WB, Casavant R, Kline DK, Cramer SC, Van de Winckel A, Kimberley TJ. Neurorehabil Neural Repair. 2020 Jun 1:1545968320924361. doi: 10.1177/1545968320924361. [Epub ahead of print]
PMID: 32476617


Expert-level automated sleep staging of long-term scalp EEG recordings using deep learning.
Abou Jaoude M, Sun H, Pellerin KR, Pavlova M, Sarkis RA, Cash SS, Westover MB, Lam AD. Sleep. 2020 Jun 1. pii: zsaa112. doi: 10.1093/sleep/zsaa112. [Epub ahead of print]
PMID: 32478820


Clinical and radiographic course of arrested cerebral adrenoleukodystrophy.
Mallack EJ, van de Stadt S, Caruso PA, Musolino PL, Sadjadi R, Engelen M, Eichler FS. Neurology. 2020 Jun 1. pii: 10.1212/WNL.0000000000009626. doi: 10.1212/WNL.0000000000009626. [Epub ahead of print]
PMID: 32482842


Risk Factors in Elite, Adolescent Male Soccer Players: Prospective Study.
Sugimoto D, Loiacono AJ, Blenis A, Morse JM, Borg DR, Meehan WP 3rd. Clin Pediatr (Phila). 2020 Jun;59(6):596-605. doi: 10.1177/0009922820916895.
PMID: 32423344


Seizure onset location shapes dynamics of initiation.
Salami P, Peled N, Nadalin JK, Martinet LE, Kramer MA, Lee JW, Cash SS. Clin Neurophysiol. 2020 May 29;131(8):1782-1797. doi: 10.1016/j.clinph.2020.04.168. [Epub ahead of print]
PMID: 32512346


Alternatives to amyloid for Alzheimer's disease therapies-a symposium report.
Cable J, Holtzman DM, Hyman BT, Tansey MG, Colonna M, Kellis M, Brinton RD, Albert M, Wellington CL, Sisodia SS, Tanzi RE. Ann N Y Acad Sci. 2020 May 29. doi: 10.1111/nyas.14371. [Epub ahead of print]
PMID: 32472577


A structural variation reference for medical and population genetics.
Collins RL, Brand H, Karczewski KJ, Zhao X, Alföldi J, Francioli LC, Khera AV, Lowther C, Gauthier LD, Wang H, Watts NA, Solomonson M, O'Donnell-Luria A, Baumann A, Munshi R, Walker M, Whelan CW, Huang Y, Brookings T, Sharpe T, Stone MR, Valkanas E, Fu J, Tiao G, Laricchia KM, Ruano-Rubio V, Stevens C, Gupta N, Cusick C, Margolin L; Genome Aggregation Database Production Team; Genome Aggregation Database Consortium, Taylor KD, Lin HJ, Rich SS, Post WS, Chen YI, Rotter JI, Nusbaum C, Philippakis A, Lander E, Gabriel S, Neale BM, Kathiresan S, Daly MJ, Banks E, MacArthur DG, Talkowski ME.
Nature. 2020 May;581(7809):444-451. doi: 10.1038/s41586-020-2287-8. Epub 2020 May 27.
PMID: 32461652


Evaluating drug targets through human loss-of-function genetic variation.
Minikel EV, Karczewski KJ, Martin HC, Cummings BB, Whiffin N, Rhodes D, Alföldi J, Trembath RC, van Heel DA, Daly MJ; Genome Aggregation Database Production Team; Genome Aggregation Database Consortium, Schreiber SL, MacArthur DG. Nature. 2020 May;581(7809):459-464. doi: 10.1038/s41586-020-2267-z. Epub 2020 May 27.
PMID: 32461653


H3.3 Nucleosome Assembly Mutants Display a Late-Onset Maternal Effect.
Burkhart KB, Sando SR, Corrionero A, Horvitz HR. Curr Biol. 2020 May 26. pii: S0960-9822(20)30560-1. doi: 10.1016/j.cub.2020.04.046. [Epub ahead of print]
PMID: 32470364


RNA delivery by extracellular vesicles in mammalian cells and its applications.
O'Brien K, Breyne K, Ughetto S, Laurent LC, Breakefield XO. Nat Rev Mol Cell Biol. 2020 May 26. doi: 10.1038/s41580-020-0251-y. [Epub ahead of print] Review.
PMID: 32457507 


Author response: RCVS2 score and diagnostic approach for reversible cerebral vasoconstriction syndrome.
Singhal AB, Rocha EA. Neurology. 2020 May 26;94(21):946. doi: 10.1212/WNL.0000000000009500.
PMID: 32451341


Temporal association of sNfL and gad-enhancing lesions in multiple sclerosis
Rosso M, Gonzalez CT, Healy BC, Saxena S, Paul A, Bjornevik K, Kuhle J, Benkert P, Leppert D, Guttmann C, Bakshi R, Weiner HL, Chitnis T.Ann Clin Transl Neurol. 2020 May 25. doi: 10.1002/acn3.51060. [Epub ahead of print]
PMID: 32452160


Medical and Paramedical Care of Patients With Cerebellar Ataxia During the COVID-19 Outbreak: Seven Practical Recommendations of the COVID 19 Cerebellum Task Force.
Manto M, Dupre N, Hadjivassiliou M, Louis ED, Mitoma H, Molinari M, Shaikh AG, Soong BW, Strupp M, Van Overwalle F, Schmahmann JD. Front Neurol. 2020 May 22;11:516. doi: 10.3389/fneur.2020.00516. eCollection 2020.
PMID: 32574247


Youth With Concussion Have Less Adaptable Gait Patterns Than Their Uninjured Peers: Implications for Concussion Management.
Howell DR, Bonnette S, Diekfuss JA, Grooms DR, Myer GD, Meehan WP 3rd.
J Orthop Sports Phys Ther. 2020 May 22:1-24. doi: 10.2519/jospt.2020.9133. [Epub ahead of print]
PMID: 32441192


Lower Grade Gliomas.
Youssef G, Miller JJ. Curr Neurol Neurosci Rep. 2020 May 22;20(7):21. doi: 10.1007/s11910-020-01040-8. Review.
PMID: 32444979


Preserving Access: A Review of Stroke Thrombectomy during the COVID-19 Pandemic.
Leslie-Mazwi TM, Fargen KM, Levitt M, Derdeyn CP, Feske SK, Patel AB, Hirsch JA. AJNR Am J Neuroradiol. 2020 May 21. doi: 10.3174/ajnr.A6606. [Epub ahead of print] Review.
PMID: 32439650


Genetic overlap and causal inferences between kidney function and cerebrovascular disease.
Marini S, Georgakis MK, Chung J, Henry JQA, Dichgans M, Rosand J, Malik R, Anderson CD. Neurology. 2020 May 21. pii: 10.1212/WNL.0000000000009642. doi: 10.1212/WNL.0000000000009642. [Epub ahead of print]
PMID: 32439819


Neural activity underlying the detection of an object movement by an observer during forward self-motion: dynamic decoding and temporal evolution of directional cortical connectivity.
Kozhemiako N, Nunes AS, Samal A, Rana KD, Calabro FJ, Hämäläinen MS, Khan S, Vaina LM. Prog Neurobiol. 2020 May 21:101824. doi: 10.1016/j.pneurobio.2020.101824. [Epub ahead of print]
PMID: 32446882


Protein changes in synaptosomes of Huntington's disease knock-in mice are dependent on age and brain region.
Sapp E, Seeley C, Iuliano M, Weisman E, Vodicka P, DiFiglia M, Kegel-Gleason KB. Neurobiol Dis. 2020 May 19;141:104950. doi: 10.1016/j.nbd.2020.104950. [Epub ahead of print]
PMID: 32439598


Reader response: Use of β2-adrenoreceptor agonist and antagonist drugs and risk of Parkinson disease.
Scherzer CR, Riise T, Locascio JJ. Neurology. 2020 May 19;94(20):898-899. doi: 10.1212/WNL.0000000000009449.
PMID: 32423986


Evidence-Based Physiatry: Efficacy of Home-Based Telerehabilitation vs In-Clinic Therapy for Adults After Stroke.
Tenforde AS, Zafonte R, Hefner J, Iaccarino MA, Silver J, Paganoni S. Am J Phys Med Rehabil. 2020 May 18. doi: 10.1097/PHM.0000000000001475.


Mutant Allele-Specific CRISPR Disruption in DYT1 Dystonia Fibroblasts Restores Cell Function
Cruz L, György B, Cheah PS, Kleinstiver BP, Eimer WA, Garcia SP, Sharma N, Ozelius LJ, Bragg DC, Joung JK, Norberto de Souza O, Macedo Timmers LFS, Breakefield XO. Mol Ther Nucleic Acids. 2020 May 15;21:1-12. doi: 10.1016/j.omtn.2020.05.009.


Commentary on Composite cognitive and functional measures for early stage Alzheimer's disease trials.
Rentz DM, Papp KV. Alzheimers Dement (Amst). 2020 May 15;12(1):e12012. doi: 10.1002/dad2.12012.


Ethical triage during the COVID-19 pandemic: a toolkit for neurosurgical resource allocation.
Hulsbergen AFC, Eijkholt MM, Balak N, Brennum J, Bolger C, Bohrer AM, Feldman Z, Holsgrove D, Kitchen N, Mathiesen TI, Moojen WA, Samprón N, Sames M, Sandvik U, Tisell M, Broekman MLD. Acta Neurochir (Wien). 2020 May 14:1-6. doi: 10.1007/s00701-020-04375-w.


Case 15-2020: A 79-Year-Old Man with Hyponatremia and Involuntary Movements of the Arm and Face.
Cooper CM, Cheung PW, Penney EB, Linnoila JJ. N Engl J Med. 2020 May 14;382(20):1943-1950. doi: 10.1056/NEJMcpc1913477.


C9orf72 suppresses systemic and neural inflammation induced by gut bacteria.
Burberry A, Wells MF, Limone F, Couto A, Smith KS, Keaney J, Gillet G, van Gastel N, Wang JY, Pietilainen O, Qian M, Eggan P, Cantrell C, Mok J, Kadiu I, Scadden DT, Eggan K. Nature. 2020 May 13. doi: 10.1038/s41586-020-2288-7. [Epub ahead of print]
PMID: 32483373


Novel Gene Fusions in Glioblastoma Tumor Tissue and Matched Patient Plasma.
Wang L, Yekula A, Muralidharan K, Small JL, Rosh ZS, Kang KM, Carter BS, Balaj L.Cancers (Basel). 2020 May 13;12(5). pii: E1219. doi: 10.3390/cancers12051219.
PMID: 32414213


Clinical trials in REM sleep behavioural disorder: challenges and opportunities.
Videnovic A, Ju YS, Arnulf I, Cochen-De Cock V, Högl B, Kunz D, Provini F, Ratti PL, Schiess MC, Schenck CH, Trenkwalder C; Treatment and Trials Working Group of the International RBD Study Group.J Neurol Neurosurg Psychiatry. 2020 May 13. pii: jnnp-2020-322875. doi: 10.1136/jnnp-2020-322875. [Epub ahead of print] Review.
PMID: 32404379


Management of Patients with Cerebellar Ataxia During the COVID-19 Pandemic: Current Concerns and Future Implications.
Manto M, Dupre N, Hadjivassiliou M, Louis ED, Mitoma H, Molinari M, Shaikh AG, Soong BW, Strupp M, Van Overwalle F, Schmahmann JD. Cerebellum. 2020 May 13:1-7. doi: 10.1007/s12311-020-01139-1. [Epub ahead of print]
PMID: 32410881


Reactivation of Motor-Related Gamma Activity in Human NREM Sleep.
Eichenlaub JB, Biswal S, Peled N, Rivilis N, Golby AJ, Lee JW, Westover MB, Halgren E, Cash SS.Front Neurosci. 2020 May 12;14:449. doi: 10.3389/fnins.2020.00449. eCollection 2020.
PMID: 32477056


Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence.
Deng W, Yin S, McMullin D, Inglessis-Azuaje I, Elmariah S, Hung J, Lo EH, Palacios IF, Buonanno FS, Ning M. Ann Intern Med. 2020 May 12. doi: 10.7326/M19-3583. [Epub ahead of print]
PMID: 32422058


Examining Cognitive Decline Across Black and White Participants in the Harvard Aging Brain Study.
Amariglio RE, Buckley RF, Rabin JS, Papp KV, Quiroz YT, Mormino EC, Sparks KP, Johnson KA, Rentz DM, Sperling RA. J Alzheimers Dis. 2020 May 12. doi: 10.3233/JAD-191291. [Epub ahead of print]
PMID: 32417775


Understanding the needs of people with ALS: a national survey of patients and caregivers.
Brizzi KT, Bridges JFP, Yersak J, Balas C, Thakur N, Galvin M, Hardiman O, Heatwole C, Ravits J, Simmons Z, Bruijn L, Chan J, Bedlack R, Berry JD.Amyotroph Lateral Scler Frontotemporal Degener. 2020 May 12:1-9. doi: 10.1080/21678421.2020.1760889. [Epub ahead of print]
PMID: 32396393


The efficacy of cannabidiol on renal angiomyolipoma and subependymal giant cell tumor volume in tuberous sclerosis complex.
Barnett JR, Grinspoon RA, Harisinghani M, Caruso PA, Thiele EA.
J Clin Neurosci. 2020 May 11. pii: S0967-5868(20)30565-8. doi: 10.1016/j.jocn.2020.05.030. [Epub ahead of print]
PMID: 32409220


A novel pathogenic frameshift variant unmasked by a large de novo deletion at 13q21.33-q31.1 in a Chinese patient with neuronal ceroid lipofuscinosis type 5.
Li W, Fan X, Zhang Y, Huang L, Jiang T, Qin Z, Su J, Luo J, Yi S, Zhang S, Shen Y. BMC Med Genet. 2020 May 11;21(1):100. doi: 10.1186/s12881-020-01039-5.
PMID: 32393339


COVID-19 in Patients with Myasthenia Gravis.
Anand P, Slama MCC, Kaku M, Ong C, Cervantes-Arslanian AM, Zhou L, David WS, Guidon AC.Muscle Nerve. 2020 May 11. doi: 10.1002/mus.26918. [Epub ahead of print]
PMID: 32392389


The Alzheimer Disease-Causing Presenilin-1 L435F Mutation Causes Increased Production of Soluble Aβ43 Species in Patient-Derived iPSC-Neurons, Closely Mimicking Matched Patient Brain Tissue.
Oakley DH, Chung M, Klickstein N, Commins C, Hyman BT, Frosch MP. J Neuropathol Exp Neurol. 2020 May 10. pii: nlaa025. doi: 10.1093/jnen/nlaa025. [Epub ahead of print]
PMID: 32388561


Sports Medicine Staffing Patterns and Incidence of Injury in Collegiate Men's Ice Hockey.
Baugh CM, Kerr ZY, Kroshus E, Lanser BL, Lindley TR, Meehan WP 3rd. J Athl Train. 2020 May 8. doi: 10.4085/1062-6050-0464.19. [Epub ahead of print]
PMID: 32383984


Visualization of PS/γ-Secretase Activity in Living Cells.
Maesako M, Sekula NM, Aristarkhova A, Feschenko P, Anderson LC, Berezovska O. iScience. 2020 May 7;23(6):101139. doi: 10.1016/j.isci.2020.101139. [Epub ahead of print]
PMID: 32438286


Delirium: a missing piece in the COVID-19 pandemic puzzle.
O'Hanlon S, Inouye SK. Age Ageing. 2020 May 6. pii: afaa094. doi: 10.1093/ageing/afaa094. [Epub ahead of print] No abstract available.
PMID: 32374367


Virtual care: new models of caring for our patients and workforce.
Schwamm LH, Estrada J, Erskine A, Licurse A. Lancet Digit Health. 2020 May 6. doi: 10.1016/S2589-7500(20)30104-7. [Epub ahead of print] PMID: 32382724


Lipocalin-2 is increased in amyotrophic lateral sclerosis.
Petrozziello T, Mills AN, Farhan SMK, Mueller KA, Granucci EJ, Glajch KE, Chan J, Chew S, Berry JD, Sadri-Vakili G. Muscle Nerve. 2020 May 5. doi: 10.1002/mus.26911. [Epub ahead of print]
PMID: 32369618 


Replay of Learned Neural Firing Sequences during Rest in Human Motor Cortex.
Eichenlaub JB, Jarosiewicz B, Saab J, Franco B, Kelemen J, Halgren E, Hochberg LR, Cash SS.
Cell Rep. 2020 May 5;31(5):107581. doi: 10.1016/j.celrep.2020.107581.
PMID: 32375031


Reply: The influence of sample size and arbitrary statistical thresholds in lesion-network mapping.
Cohen AL, Fox MD. Brain. 2020 May 4. pii: awaa095. doi: 10.1093/brain/awaa095. [Epub ahead of print] No abstract available.
PMID: 32365379


Sports Medicine Staffing Across National Collegiate Athletic Association Division I, II, and III Schools: Evidence for the Medical Model.
Baugh CM, Kroshus E, Lanser BL, Lindley TR, Meehan WP 3rd. J Athl Train. 2020 May 4. doi: 10.4085/1062-6050-0463-19. [Epub ahead of print]
PMID: 32364760


Kalirin Interacts with TRAPP and Regulates Rab11 and Endosomal Recycling.
Wang X, Weng M, Ke Y, Sapp E, DiFiglia M, Li X. Cells. 2020 May 4;9(5). pii: E1132. doi: 10.3390/cells9051132.
PMID: 32375403


A digital embrace to blunt the curve of COVID19 pandemic.
Schwamm, L.H., Erskine, A. & Licurse, A. npj Digit. Med. 3, 64. 2020 May 4.
doi: 10.1038/s41746-020-0279-6


Reply: A lack of consistent brain grey matter alterations in migraine.
Burke MJ, Fox MD. Brain. 2020 May 3. pii: awaa124. doi: 10.1093/brain/awaa124.

 Earlier Publications