Research in ischemic stroke focuses on the prevention, treatment and recovery from strokes that occur following a sudden blockage of the arteries supplying the brain.

There are almost 800,000 strokes each year in the U.S., which is the leading cause of neurological mortality and disability worldwide. Some of the questions our faculty address include:

  • How can we improve the care of patients treated with endovascular thrombectomy?
  • What genetic risk factors predispose patients to develop stroke?
  • Can new treatments prevent brain edema?
  • Can neurotechnology help with recovery after a stroke?

Faculty Studying This Topic


Bay Leslie-MazwiBay Leslie-Mazwi, MD     
Clinical profile
Research profile

Completed and Ongoing Clinical Trials

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia 

CHARM: Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction

DEFUSE-3: Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3

GAMES-RP: Glyburide Advantage in Malignant Edema and Stroke