Laboratory for Translational Neurorecovery: David J. Lin, MD
Overview and Ongoing Projects
At the core of the Laboratory for Translational Neurorecovery is a hypothesis-driven and quantitative approach to clinical research informed by both fundamental human neuroscience and neural engineering.
(I) Stroke Motor Rehabilitation and Recovery Study (SMaHRT)
The MGH Stroke Motor reHabilitation and Recovery sTudy (SMaHRT) is an observational, natural history, and interdisciplinary research study of motor recovery after stroke. We collect rehabilitation-focused outcomes starting during the acute stroke hospitalization at Massachusetts General Hospital and continuing over time across the post-acute care continuum. We are closely integrated with the MGH Neurorecovery Clinic. We apply quantitative methods to analyzing outcomes data informed by neuro- and rehab- sciences.
(II) Systems Neuroscience Subserving Stroke Motor Recovery
We apply quantitative analysis of data from neuroimaging, EEG, and Transcranial Magnetic Stimulation (TMS) to understand how neural structure and function contribute to stroke motor recovery. This work is in close collaboration with the Laboratory for Restorative Neurotechnology and the Brain Recovery Lab. To date, work in our lab has established novel and automated methods for quantifying injury to key brain structures responsible for arm motor recovery after stroke.
(III) Novel EEG Brain-Computer Interface to Enhance Arm Motor Recovery after Stroke
We are working with a multidisciplinary team to design a novel EEG-driven Brain-Computer Interface Arm Orthosis System to maximize arm motor neurorehabilitation. We inform our engineering with neuroscientific insights from the natural history of stroke recovery as well as cutting-edge neural decoding strategies. This work is in close collaboration with the Laboratory for Restorative Neurotechnology (BrainGate).
Faculty and Staff
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David J. Lin, MD Principal Investigator Director, MGH Neurorecovery Clinic | Neuro-intensivist, Mass General Instructor in Neurology, Harvard Medical School |
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Kimberly Erler, PhD, OTR/L Assistant Professor Department of Occupational Therapy MGH Institute of Health Professions |
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Julie A. DiCarlo, MS Lab Manager Clinical Research Coordinator II |
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Iris Wu, BA Data Analyst Clinical Research Coordinator II |
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Taya Hamilton, PT Physical Therapist/Clinical Neurotechnology Consultant Clinical Research Coordinator II |
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Marina Petrilli, BA Occupational Therapy Student MGH Institute of Health Professions |
Collaborators
Director, Brain Recovery Lab
Lab Alumni
Alison Cloutier, MS, Clinical Research Coordinator II
Nicole Lam, BS, Occupational Therapy Student, MGH Institute of Health Professions
Publications
See the latest publications from our laboratory.
Open Research Positions
We are always looking for passionate and talented individuals to join our team. Please email Dr. David Lin for direct inquiries.
Support
Work in the Lin Lab is currently supported by the American Academy of Neurology, the Andrew David Heitman Foundation, the American Society of Neurorehabilitation, the American Heart Association/Northeast Cerebrovascular Consortium, the Veterans Health Administration, the Mass General Center for Neurotechnology and Neurorecovery, and the Mass General Department of Neurology.
Dr. Lin has received past support from the American Heart Association/Northeast Cerebrovascular Consortium, the American Society of Neurorehabilitation, and the National Institutes of Health.
Donor support helps to advance science and enhance patient care. If you would like to make a donation to the Laboratory for Translational Neurorecovery, please visit giving.massgeneral.org, check the box to designate your gift to a specific area and note “Lin Laboratory for Translational Neurorecovery.” You can also contact Elizabeth Barberio at ebarberio@partners.org for more information.