Laboratory for Translational Neurorecovery: David J. Lin, MD
Overview and Ongoing Projects
At the core of the Laboratory for Translational Neurorecovery is a hypothesis-driven and quantitative approach to clinical research informed by both fundamental human neuroscience and neural engineering.
(I) Stroke Motor Rehabilitation and Recovery Study (SMaHRT)
The MGH Stroke Motor reHabilitation and Recovery sTudy (SMaHRT) is an observational, natural history, and interdisciplinary research study of motor recovery after stroke. We collect rehabilitation-focused outcomes starting during the acute stroke hospitalization at Massachusetts General Hospital and continuing over time across the post-acute care continuum. We are closely integrated with the MGH Neurorecovery Clinic. We apply quantitative methods to analyzing outcomes data informed by neuro- and rehab- sciences.
(II) Systems Neuroscience Subserving Stroke Motor Recovery
We apply quantitative analysis of data from neuroimaging, EEG, and Transcranial Magnetic Stimulation (TMS) to understand how neural structure and function contribute to stroke motor recovery. This work is in close collaboration with the Laboratory for Restorative Neurotechnology and the Brain Recovery Lab. To date, work in our lab has established novel and automated methods for quantifying injury to key brain structures responsible for arm motor recovery after stroke.
(III) Novel EEG Brain-Computer Interface to Enhance Arm Motor Recovery after Stroke
We are working with a multidisciplinary team to design a novel EEG-driven Brain-Computer Interface Arm Orthosis System to maximize arm motor neurorehabilitation. We inform our engineering with neuroscientific insights from the natural history of stroke recovery as well as cutting-edge neural decoding strategies. This work is in close collaboration with the Laboratory for Restorative Neurotechnology (BrainGate).
Faculty and Staff
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David J. Lin, MD Principal Investigator Director, MGH Neurorecovery Clinic | Neuro-intensivist, Mass General Instructor in Neurology, Harvard Medical School |
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Kimberly Erler, PhD, OTR/L Assistant Professor Department of Occupational Therapy MGH Institute of Health Professions |
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Julie A. DiCarlo, MS Lab Manager Clinical Research Coordinator II |
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Iris Wu, BA Data Analyst Clinical Research Coordinator II |
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Taya Hamilton, PT Physical Therapist/Clinical Neurotechnology Consultant Clinical Research Coordinator II |
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Marina Petrilli, BA Occupational Therapy Student MGH Institute of Health Professions |
Collaborators
Director, Brain Recovery Lab
Lab Alumni
Alison Cloutier, MS, Clinical Research Coordinator II
Nicole Lam, BS, Occupational Therapy Student, MGH Institute of Health Professions
Publications
See the latest publications from our laboratory.
Open Research Positions
We are seeking a highly-motivated individual to advance neurophysiological biomarkers of motor recovery after stroke. Experience with EEG acquisition and analysis is preferred, along with an interest in MRI and Transcranial Magnetic Stimulation (TMS). The goal of this study is to identify optimal neurophysiological biomarkers of upper extremity motor recovery that will directly inform the development of new neurotechnologies including Brain Computer Interfaces to improve upper extremity motor recovery.
Funding
Support the Laboratory for Translational Neurorecovery
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