Jayaraj (Jay) Rajagopal, MD, was named the new incumbent of the Bernard and Mildred Kayden Endowed MGH Research Institute Chair.
The Rajagopal laboratory is interested in modern cellular and developmental biology approaches to reframing the cellular basis of lung biology. These inquiries serve as a framework to understand how the reactivation and distortion of normal developmental processes results in human lung disease.
His laboratory made the surprising discovery that a fully mature functional cell can durably dedifferentiate into a stem cell. His lab has also identified several new principles of cell communication during regeneration, as well as several new lung cell types including the initial description of pulmonary ionocytes. Current interests include establishing the functions of this new menagerie of cells and their roles in disease.
Dr. Rajagopal is an investigator in the Center for Regenerative Medicine at Massachusetts General Hospital, a professor of medicine at Harvard Medical School and a Howard Hughes Medical Institute (HHMI) Faculty Scholar. He is also an associate member at the Broad Institute and on the faculty of the Harvard Stem Cell Institute.
He directs the Stanbury Unit of the Mass General Department of Medicine that focuses on the training of young physician-scientists and he has been a Robertson Investigator of the New York Stem Cell Institute, a Kevin and Polly Maroni MGH Research Scholar and an Outstanding Investigator of the International Society for Stem Cell Research.
Learn more about Dr. Rajagopal's work.