Emerging computational tools including 3D visualization, machine learning, and computational fluid dynamics may help identify those patients are at greatest risk.

Puchner SB et al. Iterative image reconstruction algorithms in coronary CT angiography improve the detection of lipid-core plaque--a comparison with histology. Eur Radiol. 2015 Jan;25(1):15-23.

Lu MT et al. Noninvasive Fractional Flow Reserve Derived From Coronary CT Angiography (FFRCT): Management and Outcomes in the PROMISE Trial. JACC Cardiovasc Imaging, in press.