Framingham Heart Study
Over a decade of collaboration with the Framingham Heart Study has yielded fundamental information about the relationship between coronary artery calcium, ectopic fat, and cardiovascular disease. More recent work applied the 2013 ACC/AHA statin guidelines and 2015 CMS lung cancer screening eligibility guidelines to characterize the risk of cardiovascular events and subclinical atherosclerosis in these clinically relevant populations.

Lu MT et al. Lung Cancer Screening Eligibility in the Community: Cardiovascular Risk Factors, Coronary Artery Calcification, and Cardiovascular Events. Circulation 2016;134(12):897-9.

Pursnani A et al. Guideline-Based Statin Eligibility, Coronary Artery Calcification, and Cardiovascular Events. JAMA 2015;314(2):134-41.

Cardiometabolic Disease, Cardiac Structure, and Risk
Metabolic syndrome is a well-established risk factor for cardiovascular disease (CVD). Although obesity has frequently been cited as central to CVD risk, emerging literature suggests that cardiometabolic risk may evolve independently from body mass index (BMI). The goal of this research is to understand the determinants of cardiometabolic disease and their impact on cardiac structure, function, and prognosis.

Shah RV et al. Fitness in young adulthood is associated with improved survival and cardiovascular risk: the CARDIA Study. JAMA Internal Medicine 2016; 176(1): 87-95.

Rayner J et al. Normalization of visceral fat and complete reversal of cardiovascular remodeling accompany gastric bypass, but not banding. J Am Coll Cardiol 2015; 66: 2569-2570.