Our laboratory at Massachusetts General Hospital focuses on the structure determination of macromolecules, including membrane proteins, employing electron cryomicroscopy.
Our lab at Massachusetts General Hospital studies study hepatorenal syndrome in order to understand how advanced liver disease (cirrhosis) affects kidney function.
The M. Amin Arnaout laboratory at Massachusetts General Hospital researches the molecular basis of human disease to guide development of new and safer therapies, using genetics, genomics, biochemistry, cell biology, structural and computational biology and animal models.
The Jodie L. Babitt Lab at Massachusetts General Hospital is focused on elucidating the molecular and cellular mechanisms involved in iron homeostasis
The Brown Lab at Massachusetts General Hospital researches mechanisms and signals that regulate the distribution of important proteins in the kidney, controlling urine concentration and systemic acid base balance.
The Kalim Lab at Massachusetts General Hospital conducts translational research exploring protein and metabolite alterations that occur in uremia and can contribute to the adverse outcomes of kidney disease.
The main focus in the Hua Lu Laboratory at Massachusetts General Hospital is to study the mechanism of the trafficking of a water channel protein, AQP2.
The Morizane Lab focuses on kidney disease studies using stem cell-derived tissues. Specifically, we are generating 3D kidney tissues termed organoids from human pluripotent stem cells (hPSCs). Learn more.
The primary research focus of this lab at Massachusetts General Hospital is calciphylaxis (also known as calcific uremic arteriolopathy) and it aims to develop effective treatments and diagnostic tests for patients with calciphylaxis. I am also conducting research in the areas of hyponatremia, nephrolithiasis, and olfaction-malnutrition.
The focus of the Niles Lab at Massachusetts General Hospital has been on the characterization of anti-neutrophil cytoplasmic antibodies (ANCA), the development of tests for their detection, the correlation of the presence of the antibodies with different forms of vasculitis, and the value of such tests in clinical practice.