Transplant Center Kidney/Pancreas/Islet Programs

The Kidney/Pancreas/Islet Transplant Programs at Massachusetts General Hospital provide new and unique treatment options for patients with end-stage renal disease (kidney failure) and/or type 1 diabetes.
Request an appointment or refer a patient online Download our patient guide to transplantation (PDF)

Call to request an appointment or refer a patient: 877-644-2860


Islet Cells
Islet Cells

A pioneer in organ transplantation since 1963, Massachusetts General Hospital offers patients both well-established and leading-edge treatment options for chronic kidney disease and type 1 diabetes.

Our groundbreaking work in tolerance induction for kidney transplant recipients has allowed patients to live drug-free after their transplantations. Our patients also have access to the latest clinical trials as our dedicated researchers continue to turn laboratory breakthroughs into improvements in patient care.

Learn about our programs:


High Kidney Transplant Volumes

Mass General performs significantly more kidney transplants than other Massachusetts institutions. Our high volume of kidney transplants – and skilled team of kidney transplant surgeons, anesthesiologists, nurses and social workers who guide patients through every stage of care– help us to attain excellent results in treating patients who need a kidney transplant. Learn more.

Conditions & Diseases

The links below provide more information about conditions and diseases that might be treated within this program.

  • Analgesic Nephropathy

    Analgesic nephropathy is a chronic kidney disease that gradually leads to end-stage renal disease and the need for permanent dialysis or a kidney transplant.

  • Biliary Cirrhosis / Bile Duct Cancer

    Biliary cirrhosis is a rare form of liver cirrhosis, caused by disease or defects of the bile ducts.

  • Diabetes

    Type 1 diabetes may also be known by a variety of other names, including the following: insulin-dependent diabetes mellitus (IDDM), juvenile diabetes, brittle diabetes, or sugar diabetes.

  • Diabetic Nephropathy (Kidney Disease)

    Nephropathy is the deterioration of the kidneys. The final stage of nephropathy is called end-stage renal disease, or ESRD.

  • End Stage Renal Disease (ESRD)

    Renal failure refers to temporary or permanent damage to the kidneys that results in loss of normal kidney function.

  • Glomerulonephritis

    Glomerulonephritis is a type of glomerular kidney disease in which the kidneys' filters become inflamed and scarred, and slowly lose their ability to remove wastes and excess fluid from the blood to make urine.

  • Glomerulosclerosis

    Glomerulosclerosis is the term used to describe scarring that occurs within the kidneys in the small balls of tiny blood vessels called the glomeruli.

  • Goodpasture Syndrome

    Goodpasture syndrome is a rare, autoimmune disease that can affect the lungs and kidneys.

  • Hematuria (Blood in the Urine)

    Hematuria is the presence of red blood cells (RBCs) in the urine.

  • Hemolytic Uremic Syndrome

    Hemolytic uremic syndrome is a rare condition that mostly affects children under the age of 10. It is often characterized by damage to the lining of blood vessel walls, destruction of red blood cells, and kidney failure.

  • Hypoparathyroidism

    Underactive parathyroid glands do not produce enough parathyroid hormones. This causes low levels of calcium in the blood.

  • Immunoglobulin A (IgA) Nephropathy

    IgA nephropathy is a chronic kidney disease that may progress over a period of 10 to 20 years, and can lead to end-stage renal disease.

  • Nephrotic Syndrome

    Nephrotic syndrome is a condition often characterized by the following: very high levels of protein in the urine, low levels of protein in the blood, swelling, especially around the eyes, feet, and hands, as well as high cholesterol.

  • Pancreatic Cancer

    Pancreatic cancer is the fourth most common cause of cancer death in men and women in the US. Pancreatic cancer occurs when malignant cells grow out of control.

  • Polycystic Kidney Disease

    Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts filled with fluid in the kidneys.

  • Renal Vascular Disease

    Renal vascular disease is the name given to a variety of complications that affect the arteries and veins of the kidneys.

Patient Outcomes

 Kidney Transplant Volumes

Kidney Transplant Volumes  
Mass General performs more kidney transplants than other Massachusetts institutions.

Patient Education

Mass General is dedicated to ensuring that people understand their health care choices and have the necessary information to make decisions affecting their health and well being. The related support and wellness information listed below can play a role in treatment options.



  • Kidney transplant patients meet their matches - 4/3/2012, Mass General

    John Marzelli and Esperanza Yoblonsky were suffering from IgA nephropathy and both needed a new kidney; they found the answer in the Mass General Transplant Center’s internal exchange program.

  • Andrew Johnson Bounces Back After Kidney Transplant - 9/16/2011, Mass General

    Toddler Andrew Johnson is thriving since receiving his mother’s kidney in a transplant at MassGeneral Hospital for Children.

  • A grateful family thanks MGH Transplant Center staff - 4/15/2011, Mass General

    MGH Hotline 4.15.11 When 35-year-old Eric Walker was diagnosed with kidney failure in 2006, the life of the once energetic husband and father of three young children changed completely.

  • Overcoming chronic kidney disease - 4/11/2011, Mass General

    When 14-year-old Kassie Holmes was faced with going back on dialysis or receiving a kidney transplant, Avram Traum, MD, recommended a transplant regiment that did not include steroids.

  • Transplant Center recognized for organ donation rate - 12/15/2009, Mass General

    The Department of Health and Human Services awarded the Transplant Center a Medal of Honor for its outstanding achievements in organ donation, including a donation rate of 75 percent or more eligible donors.

  • Mass General experts discuss diabetes - 11/3/2009, Mass General

    Our physicians discuss the education, management and prevention of diabetes, a condition affecting nearly 24 million adults and children in the United States.

  • Transplant Center recognized as a leader in patient education - 9/8/2009, Mass General

    Clinicians at the Transplant Center received a National Health Information Award for developing an outstanding patient education book and streamlining the patient evaluation process.

  • From transplant to triumph - 8/24/2009, Mass General

    Seven years after undergoing a groundbreaking transplant procedure developed at Massachusetts General Hospital, Jennifer Searl competes in her third World Transplant Games in Australia.

  • Transplant Center patients and donor families celebrate National Donate Life Month - 4/29/2009, Mass General

    The Transplant Center celebrated Donate Life Month by raising public awareness about the importance of organ donation and also extending thanks to the many organ donors and families who have given the generous gift of life to others.

  • New procedure, new life - 12/1/2008, Clinical

    Eight years ago, Jennifer Searl used a handicapped permit to get around campus at the University of New Hampshire. Last October, Searl, 26, ran a half-marathon and felt so good afterward she immediately signed up for another. In between these two extremes lies not only a journey of a thousand steps, but one taken along a path Searl herself blazed - with help from the Massachusetts General Hospital Transplant Center.



Contact Us

Kidney/Pancreas/Islet Transplant Programs

55 Fruit Street Boston, MA 02114
  • Near Public Transit
  • Accessible
  • Phone: 877-644-2860
Request an appointment or refer a patient online Download our patient guide to transplantation (PDF)

Call to request an appointment or refer a patient: 877-644-2860

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