pancreas

Pancreas/Islet Transplant Program

The Pancreas/Islet Transplant Program at the Massachusetts General Hospital Transplant Center provides innovative treatment, transplant and management options for patients with type 1 diabetes, including recent kidney transplant recipients.
Request an appointment Refer a patient

Call to request an appointment or refer a patient: 877-644-2860

Overview

Pancreas
Pancreas
Islet Cells
Islet Cells

 

 

 

About the Program

A regional leader in pancreas and islet transplantation, Massachusetts General Hospital continues to achieve some of the best outcomes in pancreas transplantation in the country. We are also one of the few centers in the country to offer islet transplantation, a pioneering, minimally invasive technique that replaces the insulin producing cells of the pancreas with less surgical risk and a shorter recovery time than a whole organ transplant.


For patients who require both a kidney and a pancreas or islet transplant, we offer convenient access to both procedures, as well as the ease and reassurance of receiving comprehensive, innovative care at one center.

Leadership in Islet Transplantation

The Mass General islet team is part of the multicenter Clinical Islet Transplantation Consortium (CIT), dedicated to advancing the technique of islet transplantation. We also operate the only active FDA-approved facility for the isolation and preparation of islets for human transplantation.

Patients with type 1 diabetes who are not candidates for whole organ pancreas transplantation may be eligible to undergo islet transplantation through a clinical trialcurrently underway at our Transplant Center. 

Mass General has also initiated an islet auto transplant program for patients with chronic pancreatitis, in which patients requiring surgical removal of their pancreas have the insulin-producing islets isolated from the removed pancreas and replaced in the patient’s body to prevent the development of diabetes.

To learn more about islet auto transplantation, call James Markmann, MD, PhD, at 617-643-4533.

Pancreas and Islet Transplantation Evaluation

All patients receive integrated, comprehensive care to treat their diabetes, beginning with a careful assessment and discussion with the patient to ensure that transplantation is his/her best treatment option. Candidates work with a transplant coordinator, who participates in the initial evaluation, gathers medical information and previous test results, and manages the patient’s full evaluation, which includes patient education, medical, surgical and psychosocial evaluation, and transplant-specific testing. Learn more about the pre-transplant evaluation

Pancreas transplant candidates are placed on the national United Network for Organ Sharing (UNOS) waiting list, which manages the distribution of organs nationwide. Learn more about waiting list

Post-transplant Care

After transplantation, patients are followed by our team of surgeons, endocrinologists and nurses who manage the post-transplant needs of the patient, including communication with the patient’s primary care physicians and referral to other specialists, as needed. Learn more about post-transplant care

 

Our Team

Surgeons

  • Elias, Nahel, MD, FACS

    617-726-5277

    Accepting New Patients

    Clinical Interests
    • Kidney (renal) transplant
    • Liver transplant
    • Hepatobiliary surgery
    • Liver cancer
    • Hepatocellular carcinoma, Cholangiocarcinoma, Liver tumors
    • Hepatitis C
    Board Certifications
    • Surgery
    Locations
    • Boston: Massachusetts General Hospital

  • Markmann, James F., MD, PhD

    617-643-4533

    Accepting New Patients

    Clinical Interests
    •  Pancreas and islet transplant
    • Hepatobiliary surgery
    • Vascular access for hemodialysis
    • Kidney (renal) transplant
    • Minimally Invasive Surgery
    • Liver Transplant
    Board Certifications
    • Surgery
    Locations
    • Boston: Massachusetts General Hospital

  • Yeh, Heidi MD

    617-726-6631

    Accepting New Patients

    Board Certifications
    • Surgery
    Locations
    • Boston: Massachusetts General Hospital

  • Kawai, Tatsuo MD, PhD

    617-726-0289

    Accepting New Patients

    Clinical Interests
    • Laparoscopic donor nephrectomy
    • Organ transplantation (kidney, liver and pancreas)
    • Vascular access surgery for renal failure
    Locations
    • Boston: Massachusetts General Hospital

  • Kimura, Shoko MD

    617-643-4533

    Accepting New Patients

    Locations
    • Boston: Massachusetts General Hospital
  • Dageforde, Leigh Anne MD, MPH

    617-726-5277

    Accepting New Patients

    Clinical Interests
    • Transplant surgery
    • Hepatobiliary surgery
    • Hepatocellular carcinoma, Cholangiocarcinoma, Liver tumors
    • Liver cancer
    • Hepatocellular carcinoma
    • Liver transplant
    • Liver surgery
    • Kindney (renal) transplant
    • Pancreas and islet transplant
    • Kidney disease in solid organ transplant recipients
    • Kidney disease
    • Liver tumors
    • Liver, billary and pancreatic disease
    • Liver disease
    • Liver tumors
    • Liver, billary and pancreatic disease
    • Liver disease
    • Liver failure
    Board Certifications
    • Surgery
    Locations
    • Boston: Massachusetts General Hospital

  • Cosimi, Benedict MD

    617-726-5277

    Accepting New Patients

    Clinical Interests
    • Hepatobiliary surgery
    • Melanoma
    • Gastrointestinal surgery
    • Kidney (renal) transplant
    Board Certifications
    • Surgery
    Locations
    • Boston: Massachusetts General Hospital

Diabetologists/Endocrinologists

  • Nathan, David M., MD

    617-726-8722

    Accepting New Patients

    Clinical Interests
    • Diabetes management
    • Endocrinology
    • Intensive therapies of diabetes
    Board Certifications
    • Internal Medicine
    • Endocrinology
    • Diabetes & Metabolism
    Locations
    • Boston: Massachusetts General Hospital

  • Cagliero, Enrico, MD

    617-726-8722

    Accepting New Patients

    Clinical Interests
    • Diabetes management
    • Endocrinology
    • Lipid disorders
    Board Certifications
    • Internal Medicine
    • Endocrinology
    • Diabetes & Metabolism
    Locations
    • Boston: Massachusetts General Hospital

Infectious Disease Specialists

  • Fishman, Jay, MD

    617-726-3812

    Accepting New Patients

    Clinical Interests
    • Infection in immunocompromised hosts
    • Viral and fungal infections
    • Medical education
    • Infections after transplant
    • Molecular diagnostics
    • Infectious diseases
    Board Certifications
    • Infectious Disease
    Locations
    • Boston: Massachusetts General Hospital

  • Kim, Arthur, MD

    617-726-3906

    Accepting New Patients

    Clinical Interests
    • Hepatitis B virus (HBV)
    • Hepatitis C virus (HCV)
    • AIDS and HIV infection
    • HIV/HCV coinfection
    • Substance abuse
    • Travel medicine
    • Immunocompromised patient
    • Immunology
    Board Certifications
    • Internal Medicine
    • Infectious Disease
    Locations
    • Boston: Massachusetts General Hospital

  • Kotton, Camille, MD

    617-724-0082

    Accepting New Patients

    Clinical Interests
    • Vaccines and immunizations
    • Reducing infectious risks in Transplant recipients
    • Immunocompromised patient
    Board Certifications
    • Infectious Disease
    Locations
    • Boston: Massachusetts General Hospital

  • Poznansky, Mark, MD, PhD

    617-726-3906

    Accepting New Patients

    Locations
    • Boston: Massachusetts General Hospital

  • Rosenberg, Eric, MD

    617-724-7519

    Not Accepting New Patients

    Clinical Interests
    • Infectious diseases
    • Clinical microbiology
    Board Certifications
    • Infectious Disease
    Locations
    • Boston: Massachusetts General Hospital

  • El-Khoury, Joseph, MD

    617-726-3906

    Accepting New Patients

    Board Certifications
    • Infectious Disease
    Locations
    • Boston: Massachusetts General Hospital
  • Mansour, Michael, MD, PhD

    617-726-6726

    Accepting New Patients

    Board Certifications
    • Internal Medicine
    • Infectious Disease
    Locations
    • Boston: Massachusetts General Hospital

  • Letourneau, Alyssa, MD

    617-726-3812

    Accepting New Patients

    Clinical Interests
    • Immunocompromised patient
    • Mycobacterial infection
    Board Certifications
    • Pediatrics
    • Internal Medicine
    • Infectious Disease
    Locations
    • Boston: Massachusetts General Hospital

  • Turbett, Sarah, MD

    617-726-3812

    Accepting New Patients

    Board Certifications
    • Internal Medicine
    • Infectious Disease
    Locations
    • Boston: Massachusetts General Hospital

  • Sen, Pritha, MD

    617-726-3812

    Accepting New Patients

    Board Certifications
    • Internal Medicine
    • Infectious Disease
    Locations
    • Boston: Massachusetts General Hospital

Psychiatrists

  • Ivkovic, Ana, MD

    617-726-2984

    Accepting New Patients

    Board Certifications
    • Psychiatry
    Locations
    • Boston: Massachusetts General Hospital

  • Purcell, John, MD

    617-726-1736

    Accepting New Patients

    Clinical Interests
    • Anxiety
    • Depression
    • Psychiatry
    Board Certifications
    • Psychiatry
    Locations
    • Boston: Massachusetts General Hospital

  • Prager, Laura, MD

    617-724-5600

    Accepting New Patients

    Board Certifications
    • Child & Adolescent Psychiatry
    • Psychiatry
    Locations
    • Boston: Massachusetts General Hospital

  • Smith, Felicia, MD

    617-643-6349

    Accepting New Patients

    Clinical Interests
    • Emergency psychiatry
    • Psychosomatic medicine
    Board Certifications
    • Psychiatry
    • Psychosomatic Medicine
    Locations
    • Boston: Massachusetts General Hospital

  • Kolappa, Kavitha, MD, MPH

    617-726-2984

    Accepting New Patients

    Locations
    • Boston: Massachusetts General Hospital

Conditions & Diseases

The links below provide more information about conditions and diseases that might be treated within this program.

  • Analgesic Nephropathy

    Analgesic nephropathy is a chronic kidney disease that gradually leads to end-stage renal disease and the need for permanent dialysis or a kidney transplant.

  • Biliary Cirrhosis / Bile Duct Cancer

    Biliary cirrhosis is a rare form of liver cirrhosis, caused by disease or defects of the bile ducts.

  • Diabetes

    Type 1 diabetes may also be known by a variety of other names, including the following: insulin-dependent diabetes mellitus (IDDM), juvenile diabetes, brittle diabetes, or sugar diabetes.

  • Diabetic Nephropathy (Kidney Disease)

    Nephropathy is the deterioration of the kidneys. The final stage of nephropathy is called end-stage renal disease, or ESRD.

  • End Stage Renal Disease (ESRD)

    Renal failure refers to temporary or permanent damage to the kidneys that results in loss of normal kidney function.

  • Glomerulonephritis

    Glomerulonephritis is a type of glomerular kidney disease in which the kidneys' filters become inflamed and scarred, and slowly lose their ability to remove wastes and excess fluid from the blood to make urine.

  • Glomerulosclerosis

    Glomerulosclerosis is the term used to describe scarring that occurs within the kidneys in the small balls of tiny blood vessels called the glomeruli.

  • Goodpasture Syndrome

    Goodpasture syndrome is a rare, autoimmune disease that can affect the lungs and kidneys.

  • Hematuria (Blood in the Urine)

    Hematuria is the presence of red blood cells (RBCs) in the urine.

  • Hemolytic Uremic Syndrome

    Hemolytic uremic syndrome is a rare condition that mostly affects children under the age of 10. It is often characterized by damage to the lining of blood vessel walls, destruction of red blood cells, and kidney failure.

  • Hypoparathyroidism

    Underactive parathyroid glands do not produce enough parathyroid hormones. This causes low levels of calcium in the blood.

  • Immunoglobulin A (IgA) Nephropathy

    IgA nephropathy is a chronic kidney disease that may progress over a period of 10 to 20 years, and can lead to end-stage renal disease.

  • Nephrotic Syndrome

    Nephrotic syndrome is a condition often characterized by the following: very high levels of protein in the urine, low levels of protein in the blood, swelling, especially around the eyes, feet, and hands, as well as high cholesterol.

  • Pancreatic Cancer

    Pancreatic cancer is the fourth most common cause of cancer death in men and women in the US. Pancreatic cancer occurs when malignant cells grow out of control.

  • Polycystic Kidney Disease

    Polycystic kidney disease (PKD) is a genetic disorder characterized by the growth of numerous cysts filled with fluid in the kidneys.

  • Renal Vascular Disease

    Renal vascular disease is the name given to a variety of complications that affect the arteries and veins of the kidneys.

News

  • Kidney transplant patients meet their matches - 4/3/2012, Mass General

    John Marzelli and Esperanza Yoblonsky were suffering from IgA nephropathy and both needed a new kidney; they found the answer in the Mass General Transplant Center’s internal exchange program.

  • Andrew Johnson Bounces Back After Kidney Transplant - 9/16/2011, Mass General

    Toddler Andrew Johnson is thriving since receiving his mother’s kidney in a transplant at MassGeneral Hospital for Children.

  • A grateful family thanks MGH Transplant Center staff - 4/15/2011, Mass General

    MGH Hotline 4.15.11 When 35-year-old Eric Walker was diagnosed with kidney failure in 2006, the life of the once energetic husband and father of three young children changed completely.

  • Overcoming chronic kidney disease - 4/11/2011, Mass General

    When 14-year-old Kassie Holmes was faced with going back on dialysis or receiving a kidney transplant, Avram Traum, MD, recommended a transplant regiment that did not include steroids.

  • Transplant Center recognized for organ donation rate - 12/15/2009, Mass General

    The Department of Health and Human Services awarded the Transplant Center a Medal of Honor for its outstanding achievements in organ donation, including a donation rate of 75 percent or more eligible donors.

  • Mass General experts discuss diabetes - 11/3/2009, Mass General

    Our physicians discuss the education, management and prevention of diabetes, a condition affecting nearly 24 million adults and children in the United States.

  • Transplant Center recognized as a leader in patient education - 9/8/2009, Mass General

    Clinicians at the Transplant Center received a National Health Information Award for developing an outstanding patient education book and streamlining the patient evaluation process.

  • From transplant to triumph - 8/24/2009, Mass General

    Seven years after undergoing a groundbreaking transplant procedure developed at Massachusetts General Hospital, Jennifer Searl competes in her third World Transplant Games in Australia.

  • Transplant Center patients and donor families celebrate National Donate Life Month - 4/29/2009, Mass General

    The Transplant Center celebrated Donate Life Month by raising public awareness about the importance of organ donation and also extending thanks to the many organ donors and families who have given the generous gift of life to others.

  • New procedure, new life - 12/1/2008, Clinical

    Eight years ago, Jennifer Searl used a handicapped permit to get around campus at the University of New Hampshire. Last October, Searl, 26, ran a half-marathon and felt so good afterward she immediately signed up for another. In between these two extremes lies not only a journey of a thousand steps, but one taken along a path Searl herself blazed - with help from the Massachusetts General Hospital Transplant Center.

Video

Contact

Contact Us

Kidney Transplant Programs

165 Cambridge St. Suite 301 Boston, MA 02114
  • Near Public Transit
  • Accessible
  • Phone: 877-644-2860
Request an appointment Refer a patient

Call to request an appointment or refer a patient: 877-644-2860

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