Group Members

Jochen K Lennerz, MD, PhD

Medical Director, Center for Integrated Diagnostics, Massachusetts General Hospital
Assistant Professor of Pathology, Harvard Medical School

Dr. Lennerz is board-certified in Anatomic-and Molecular Genetic Pathology and joined Mass General Department of Pathology and Center for Integrated Diagnostics as a staff pathologist and assistant professor in 2014.  Dr. Lennerz trained as a pathologist assistant in Berlin Germany (1994) and studied both medicine and molecular medicine at the University Erlangen Germany where he also received his MD, PhD.  He did his residency training in Anatomic Pathology (2008) and a fellowship in Molecular Genetic Pathology (2009) at Washington University in St. Louis.  After completion of a two-year gastrointestinal and liver pathology fellowship at Mass General (2011), he led a research group on biomarkers in lymphoma at Ulm University Germany.  Dr. Lennerz joined the CID in 2014 and his interests are biomarkers, digital pathology, and financial sustainability of molecular genetic diagnostics.

Lauren Ritterhouse, MD, PhD

Associate Director, Center for Integrated Diagnostics, Massachusetts General Hospital
Assistant Professor of Pathology, Harvard Medical School

A. John Iafrate, MD, PhD

Professor of Pathology, Massachusetts General Hospital
Professor of Pathology, Harvard Medical School
Vice Chair of Academic Affairs

Dr. Iafrate is a board-certified pathologist who joined Mass General in 2005. He formerly directed the Center for Integrated Diagnostics at Mass General and oversees a translational research laboratory that supports both Pathology and the Mass General Cancer Center. He is an MD, PhD, having received his dual degree from the State University of New York at Stony Brook in 2000 and was trained in Anatomic and Molecular Genetic Pathology at Brigham and Women’s Hospital. His post-doctoral work involved the discovery and description of a novel source of human genetic diversity termed copy number variation (CNV). Since arriving at MGH, he has established a cancer diagnostics lab focusing on genetic fingerprints that help guide novel targeted therapies. His laboratory launched SNAPSHOT several years ago, an assay that tests over 100 of the most common mutations in tumors. His research is focused on lung and brain tumors, and he has been closely involved in the clinical development of crizotinib and companion diagnostics in ALK-positive lung cancers. 

 

Long Phi Le, MD, PhD

Assistant in Pathology, Massachusetts General Hospital
Assistant Professor of Pathology, Harvard Medical School
Director of Computational Pathology 

Long Phi Le is an Associate Chief of Informatics at Massachusetts General Hospital (MGH), Director of Computational Department in Pathology at MGH, Director of Technology and Development for the Center for Integrated Diagnostics at MGH, Assistant Pathologist at MGH and an Assistant Professor of Pathology at the Harvard Medical School. He is a graduate of Massachusetts Institute of Technology (1999) and received his MD and PhD from the University of Alabama at Birmingham School of Medicine in 2006. He completed his residency training in Clinical Pathology at the Massachusetts General Hospital and his Molecular Genetic Pathology Fellowship at Brigham and Women's Hospital (2010). He joined the Mass General Pathology Department in 2010.

 

Dora Dias-Santagata, PhD, FACMG

Assistant Molecular Pathologist, Massachusetts General Hospital
Assistant Professor of Pathology, Harvard Medical School

Dr. Dias-Santagata is board-certified in Clinical Molecular Genetics and joined the Mass General staff in 2007 to co-direct the Translational Research Laboratory, a mutual collaboration between the Mass General Department of Pathology and the Cancer Center. She received her PhD from the Mount Sinai School of Medicine in New York (2004), and pursued post-doctoral research work at the Brigham and Women’s Hospital in Boston. She developed and co-directed the clinical implementation of SNaPshot, a pioneering tumor genotyping strategy that has been adopted by the oncology community at Mass General since March 2009, to help guide therapeutic decisions. Her research efforts include the molecular characterization of rare malignancies, lung and thyroid cancers, in an effort to uncover underlying genetic driver amenable for therapeutic intervention and mechanisms of acquired resistance to therapy. 

 

Miguel N. Rivera, MD

Assistant in Pathology, Massachusetts General Hospital
Assistant Professor of Pathology, Harvard Medical School

Dr. Rivera is a board certified pathologist who directs a research laboratory at the Mass General Department of Pathology and the Mass General Cancer Center. He also serves as attending physician in the Center for Integrated Diagnostics at Mass General. Dr. Rivera received an AB in Molecular Biology from Princeton University in 1996 and an MD from Harvard Medical School in 2001. He completed his Anatomic Pathology residency at Brigham and Women’s Hospital and a fellowship in Molecular Diagnostics at the Harvard Combined Program. During his postdoctoral fellowship, Dr. Rivera identified the tumor suppressor gene WTX which is implicated in both tumor formation and stem cell biology. His research currently focuses on the connections between cancer and normal developmental processes and on the use of genomic technologies to identify pathways that are active in tumors and that may serve as therapeutic targets.

 

Valentina Nardi, MD

Assistant in Pathology, Massachusetts General Hospital
Instructor, Harvard Medical School

Dr. Nardi received her MD degree and board certification in Hematology in Genoa, Italy. She pursued post-doctoral research in Boston, under the supervision of Dr. George Daley at Children's Hospital Boston, developing an interest and expertise in chronic myeloid leukemia, resistance to targeted therapies, and development and applications of new technologies to detect and monitor drug resistance over time. Dr. Nardi developed an interest in molecular diagnostics and went on to complete her Anatomic Pathology residency and a Hematopathology fellowship at the Massachusetts General Hospital and the Harvard Medical School Molecular Genetic Pathology Fellowship.

 


Leadership Team

Julie Miller Batten, MLS (ASCP)
Operations Director, Center for Integrated Diagnostics

A. Bernard Collins
Outreach and Clinical Affiliates Manager, Department of Pathology
Technical Director, Research and Development Immunopathology Unit
Associate in Pathology, Harvard Medical School

Nick Jessop
Case Manager, Center for Integrated Diagnostics

Hetal Marble, PhD
Manager of the Translational Research Lab, Center for Integrated Diagnostics

Contact

For Technical Questions: 617-643-2716

For Billing, Specimen Submission, and Testing Status Questions: 617-724-1285